Patents by Inventor Mark R. Hellberg

Mark R. Hellberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 15-fluoro prostaglandins as ocular hypotensives
    Patent number: 6649653
    Abstract: 15-Fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: November 18, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • Lipoxin A4 and its analogs for the treatment of dry eye
    Patent number: 6645978
    Abstract: Ophthalmic compositions containing Lipoxin A4 and its analogs and methods of their use for treating dry eve are disclosed.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: November 11, 2003
    Assignee: Alcon, Inc.
    Inventors: Daniel A. Gamache, Gustav Graff, Mark R. Hellberg, Peter G. Klimko, John M. Yanni
  • Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac
    Patent number: 6646003
    Abstract: The topical use of certain flurbiprofen amide derivatives and ketorolac amide derivatives to treat ophthalmic angiogenesis-related and inflammatory disorders of the posterior segment of the eye is disclosed.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: November 11, 2003
    Assignee: Alcon, Inc.
    Inventors: Gustav Graff, Mark R. Hellberg, John M. Yanni
  • Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
    Patent number: 6646001
    Abstract: Disclosed are methods and compositions for the treatment of glaucoma and ocular hypertension, comprising the administration of a prostaglandin FP receptor agonist and a prostaglandin synthesis inhibitor.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: November 11, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Mark R. Hellberg, Jon C. Nixon
  • Compounds with 5-ht1a activity useful for treating disorders of the outer retina
    Publication number: 20030207890
    Abstract: Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A against activity are disclosed.
    Type: Application
    Filed: September 9, 2002
    Publication date: November 6, 2003
    Inventors: Robert J Collier, Michael A Kapin, Mark R Hellberg, Thomas R Dean
  • Serotonergic 5HT2 agonists for treating glaucoma
    Publication number: 20030203912
    Abstract: Compounds with 5HT2 receptor agonist activity useful for treating glaucoma, including lowering intraocular pressure. Compositions and methods for their use are also disclosed.
    Type: Application
    Filed: May 9, 2003
    Publication date: October 30, 2003
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Mark R. Hellberg
  • Compounds with 5-ht activity useful for controlling visual field loss
    Publication number: 20030119846
    Abstract: Compounds with 5-HT1A agonist activity which are useful for controlling the visual field loss associated with glaucoma are disclosed.
    Type: Application
    Filed: September 9, 2002
    Publication date: June 26, 2003
    Inventors: Robert J. Collier Jr, Mark R. Hellberg, Thomas R. Dean
  • Compounds with 5-ht2 and 5-ht1a agonist activity for treating glaucoma
    Publication number: 20030114512
    Abstract: Compounds with both 5-HT2 and 5-HT1A agonist activity which are useful for lowering and controlling IOP and the treatment of glaucomatous optic neuropathy.
    Type: Application
    Filed: September 9, 2002
    Publication date: June 19, 2003
    Inventors: Robert J Collier, Thomas R Dean, Mark R Hellberg
  • Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
    Patent number: 6552084
    Abstract: Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders are disclosed.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: April 22, 2003
    Assignee: Alcon Universal Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, John R. Falck, Raymond E. Conrow
  • Treatment of disorders of the outer retina
    Patent number: 6509355
    Abstract: This invention is directed to the use of glutamate antagonists to treat the disorders of outer retina.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: January 21, 2003
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert J. Collier, Jr., Mark R. Hellberg, Michael A. Kapin, George E. Barnes, Michael L. Chandler
  • Disulfide derivatives useful for treating allergic diseases
    Patent number: 6506802
    Abstract: Novel disulfide derivatives useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The disulfide derivatives act as mast cell stabilizers.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: January 14, 2003
    Assignee: Alcon Universal Ltd.
    Inventors: Zixia Feng, Mark R. Hellberg, Steven T. Miller
  • Use of proteasome inhibitors to treat dry eye disorders
    Publication number: 20030008910
    Abstract: Proteasome inhibitors are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
    Type: Application
    Filed: May 17, 2002
    Publication date: January 9, 2003
    Applicant: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg
  • Disulfide derivatives useful for treating allergic diseases
    Patent number: 6500864
    Abstract: Novel disulfide derivatives useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The disulfide derivatives act as mast cell stabilizers.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: December 31, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Zixia Feng, Mark R. Hellberg, Steven T. Miller
  • Disulfide derivatives useful for treating allergic diseases
    Publication number: 20020193633
    Abstract: Novel disulfide derivatives useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The disulfide derivatives act as mast cell stabilizers.
    Type: Application
    Filed: May 22, 2002
    Publication date: December 19, 2002
    Inventors: Zixia Feng, Mark R. Hellberg, Steven T. Miller
  • Disulfide derivatives useful for treating allergic diseases
    Publication number: 20020193634
    Abstract: Novel disulfide derivatives useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The disulfide derivatives act as mast cell stabilizers.
    Type: Application
    Filed: May 22, 2002
    Publication date: December 19, 2002
    Inventors: Zixia Feng, Mark R. Hellberg, Steven T. Miller
  • Compositions containing a benzamide disulfide derivative for treating allergic diseases
    Patent number: 6492418
    Abstract: Methods and compositions for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The compositions contain a mast cell stabilizing disulfide derivative as an active ingredient.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: December 10, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Steven T. Miller, Mark R. Hellberg, Zixia Feng
  • Disulfide derivatives useful for treating allergic diseases
    Patent number: 6492552
    Abstract: Novel disulfide derivatives useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The disulfide derivatives act as mast cell stabilizers.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: December 10, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Zixia Feng, Mark R. Hellberg, Steven T. Miller
  • Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac
    Publication number: 20020183376
    Abstract: The topical use of certain flurbiprofen amide derivatives and ketorolac amide derivatives to treat ophthalmic angiogenesis-related and inflammatory disorders of the posterior segment of the eye is disclosed.
    Type: Application
    Filed: March 7, 2002
    Publication date: December 5, 2002
    Applicant: Alcon, Inc.
    Inventors: Gustav Graff, Mark R. Hellberg, John M. Yanni
  • 15-fluoro prostaglandins as acular hypotensives
    Publication number: 20020151587
    Abstract: 15-fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Application
    Filed: March 18, 2002
    Publication date: October 17, 2002
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • Aniline disulfide derivatives for treating allergic diseases
    Patent number: 6452052
    Abstract: Methods and compositions for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The compositions contain a mast cell stabilizing disulfide derivative as an active ingredient.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: September 17, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Mark R. Hellberg, Zixia Feng, Steven T. Miller