Abstract: The present invention relates to compounds of formula 1 or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, stroke, alopecia, CNS disorders, neurodegenerative disorders, or diabetes.

Abstract: The present invention relates to 18-methyl-6,7-methylene-17-pregn-4-ene-21,17?-carbolactones of general formula I wherein the 6,7-methylene group can be in ?- or ? position, pharmaceutical preparations containing at least one isomer of formula I and use thereof in the treatment of endometriosis.

Abstract: A method relates to authority checks governing user access to business object attachments in a store of business object attachments. The business object attachments are semantically associated with business objects of one or more remote computer systems. The method includes, at a content management interface layer that is communicatively coupled to the store of business object attachments, sending a request for user authority checks on a parent business object of a business object attachment to an originating computer system and receiving results of the user authority checks from the originating computer system.

Abstract: The invention relates to AKR1C3 inhibitors and to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular bleeding disorders and endometriosis.

Abstract: A navigation system may display a map element represented by a spline including a plurality of vertices. Label coordinate values derived from coordinate values of the plurality of vertices may be retrieved from a database. A label assigned to the map element may be displayed based on the stored label coordinate values. The assigned label may be adapted to the geometric form of at least a portion of the map element.

Abstract: A navigation device comprises a search tree which indicates next valid characters. The search tree has a plurality of nodes. The nodes are respectively associated with a character. At least some of the nodes respectively include a predetermined indicator to indicate that there is an alternate spelling for a character with which the respective node is associated. A processor is configured to receive a character input and to identify at least one next valid character using the search tree. The processor is configured to identify the at least one next valid character in dependence on whether the predetermined indicator in the search tree indicates that another character has an alternate spelling, the alternate spelling of the other character being the character input.

Abstract: A method evaluates two scattered-light signals in a hazard alarm operating in accordance with the scattered light principle. The particles to be detected are irradiated with light in a first wavelength range and with light in a second wavelength range. The light scattered by the particles is converted into a first and second non-normalized scattered light signal. The two scattered light signals are normalized in relation to one another such that their amplitude curve approximately coincides for larger particles such as dust and steam. The two normalized scattered light signals are transformed into a polar angle and a distance as polar coordinates of a polar coordinate system. Finally a respective smoke density signal and a respective dust/steam density signal is formed from a current distance value, wherein for this purpose the respective current distance values, depending on a current polar angle value, are weighted in opposition to one another.

Abstract: An improved circuit interrupter assembly provides enablement of an interlock feature for a circuit interrupter situated within a cabinet having an external handle for switching the circuit interrupter between ON and OFF conditions when the cabinet door is closed. The improved circuit interrupter assembly includes a motion transfer apparatus that provides such enablement of the interlock feature for cabinets of any of a variety of depths. The motion transfer apparatus includes a Bowden cable that extends between a first retention assembly situated at the door of the cabinet and a second retention assembly situated at the interlock feature of the circuit interrupter. The Bowden cable has a biased drive cable that extends between a pair of elements and which thus transfers the motion of the cabinet door in its closed position to enable cooperation with the interlock.

Abstract: An improved circuit breaker switch handle extension is described. The circuit breaker switch handle extension is used to control and limit operation of a circuit breaker switch handle to which it is attached. The handle extension includes positive stop features that prevent damage or destruction of the circuit breaker switch handle when excessive or undesirable force is applied to the handle extension.

Abstract: A method and apparatus for locating a transponder is provided. A carrier signal is transmitted by a base station and a transponder transmits a locating signal that is generated through phase modulation and backscattering of the carrier signal sent by the base station when the transponder is within a transmission range of the base station, whereby the transponder is located on the basis of the locating signal.

Abstract: The invention relates to system and method for generating a 3-dimensional representation of a tunnel. Road network data is provided having a plurality of road segments, at least one road segment being a tunnel road segment, including the information that said at least one road segment is a road segment located in a tunnel. The tunnel segment in the road network is identified, providing a geographical elevation map including elevation data of the geographical region in which the tunnel road segment is located, providing predefined patterns representing predefined parts of a 3-dimensional tunnel body, generating the 3-dimensional representation of the tunnel based on the tunnel road segment, the elevation map and the predefined patterns, and storing the 3-dimensional representation of the tunnel in connection with the road network as a 3-dimensional object which is located at the geographical position of the tunnel road segment.

Abstract: A system may generate a database of a geographical map of a navigation device. The geographical map covering a geographical area which is divided into several update regions. The system may identify at least one object in the geographical map which covers an object area in the geographical area. The object area can be divided into different parts which are located in different update regions. The system can store in the database, for each of said at least one object, information indicating that the object area overlaps with plural update regions, the information including pointers to update regions in which the respective different parts of the object area are stored.

Abstract: A head restraint with a basic structure which serves to adjust the head restraint and to receive a person's head. The basic structure has a holding structure and at least one framework structure, wherein the framework structure has flexurally elastic flanks and deflectable cross struts which lie between the flanks and are arranged on the flanks via an elastic connector, as a result of which a force pulse which acts on the cross struts of the at least one framework structure via a flexurally elastic flank and which acts on a front side of the at least one framework structure from one direction causes a compensating, autoreactive deformation of the at least one framework structure at another point in the opposite direction.

Abstract: A vehicle navigation system includes a map database storing map data. The map data has links representing road segments, road number icons, and additional road information icons. At least one of the links is associated with at least one of the road number icons and at least one of the additional road information icons. The vehicle navigation system may furthermore include a processing unit coupled to the map database and configured to control outputting of route guidance information via an output device. The outputting of route guidance information may include displaying a road number icon and an additional road information icon together with a link if the link is associated with the road number icon and the additional road information icon.

Abstract: A method and apparatus for locating a transponder is provided. A carrier signal is transmitted by a base station and a transponder transmits a locating signal that is generated through phase modulation and backscattering of the carrier signal sent by the base station when the transponder is within a transmission range of the base station, whereby the transponder is located on the basis of the locating signal.

Abstract: A smartphone or media player mobile communication terminal features a camera, an output unit, a data memory and a processor connected thereto. The data memory stores applications. The applications are loaded and executed by the processor. A fire alarm application is stored in the data memory, which in response to a user request, is loaded by the processor and executed. The fire alarm application features suitable program elements for analyzing the video image data recorded by the camera in respect of at least one item of information characteristic of fire and, if this information is present, for outputting an alarm via the output unit. The fire alarm application can be downloaded from an online Internet store portal for computer programs and designed for execution on the portable mobile communication terminal.

Abstract: A navigation system may use digital maps to represent cartographic features during guidance along a route to a destination requested by a user. A system and method are provided for management of icons used to represent the cartographic features by storing data for multiple icons in a data array representing an image containing the plurality of icons.

Abstract: The invention concerns a composition comprising as component (A): 10% to 97% by weight, based on the total weight of the composition, of one or more monocarboxylic esters of the general formula R1—CO—OR2, in which R1 is a saturated or unsaturated, branched or straight-chain, aliphatic group having 11 to 23 carbon atoms and R2 is a branched or straight-chain aliphatic group, a cycloaliphatic group or aromatic group having 1 to 13 carbon atoms, and the sum of the carbon atoms of the groups R1 and R2 is not more than 30, the monocarboxylic ester or esters possessing a boiling point of more than 250° C. under a standard pressure of 101.3 kPa, and as component (B): 3% to 90% by weight, based on the total weight of the composition, of one or more dispersants, the composition possessing a viscosity at 25° C. of less than 5000 mPas. The invention further concerns the use of the composition as a dispersion medium, millbases obtained from the composition, and the use of the millbases.

Abstract: A system and method for parameter driven data format conversion in a client/server architecture are disclosed. A format conversion framework is provided in a protocol layer between the client and the server. The format conversion framework passes a format conversion identifier (ID) with a request from the client from the client to the server. A conversion module is looked up by the format conversion framework based on the format conversion ID, the conversion module providing a conversion routine. The format conversion framework then executes the conversion routine on a result returned from the server to the client based on the request, the conversion routine converting a format of the result into a format used by the client.

Abstract: A method relates to authority checks governing user access to business object attachments in a store of business object attachments. The business object attachments are semantically associated with business objects of one or more remote computer systems. The method includes, at a content management interface layer that is communicatively coupled to the store of business object attachments, sending a request for user authority checks on a parent business object of a business object attachment to an originating computer system and receiving results of the user authority checks from the originating computer system.