Abstract: Compounds and compositions that deliver both uridine and ketoleucine are useful in treating disorders characterized by diminished muscle strength or diminished muscle lean mass. One such a compound is 5?-O-ketoleucyl-2?,3?-di-O-acetyluridine.

Abstract: A coated substrate comprising a coating extending over at least a part of the substrate. The coating is obtainable from a coating composition comprising (a) a polymeric binder; and (b) a feathering reducing agent comprising a carboxylic acid reactive functional group. The coated portion of the substrate comprises a pretreatment layer. The pretreatment layer is obtainable from a pretreatment composition that comprises a trivalent chromium compound. The invention extends to a method of coating a pre-treated substrate and a coated package, such as a metal can.

Abstract: Disclosed herein is a system for storing gas at almost constant pressure, which involves the injection and withdrawal of a liquid in a process known as hydraulic compensation. This disclosure teaches a way to minimize that dissolution by ensuring that, as the gas containment is charged up, the hydraulic compensation liquid emerges from the containment at the gas storage pressure and the pressure of that liquid is caused to fall in a number of discrete steps with settling volumes present at the nodes between these steps. These settling volumes enable some gas to come out of solution at each node having lost relatively small amounts of pressure. The gas is compressed back up to storage pressure and re-injected into the main storage containment without significant use of energy.

Abstract: Disclosed are systems and methods for generating graphical displays of analyte data and/or health information. In some implementations, the graphical displays are generating based on a self-referential dataset that are modifiable based on identified portions of the data. The modified graphical displays can indicate features in the analyte data of a host.

Abstract: A coating composition comprising (a) a polyester binder material; and (b) a feathering reducing agent. The feathering reducing agent is selected from (i) an acrylic feathering reducing agent comprising a functional group selected from hydroxyl, epoxide, phosphatized epoxide and/or acid-functional; (ii) a hydroxy-functional polyester feathering reducing agent; (iii) a feathering reducing agent comprising a functional group selected from amine, amide, imine and/or nitrile; (iv) a phosphatized epoxy feathering reducing agent; (v) a phenolic resin feathering reducing agent; and/or (vi) a feathering reducing agent comprising an oxazolyl functional group. The invention extends to a substrate coated with the coating composition and use of the coating composition to reduce feathering.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: Disclosed are systems and methods for generating graphical displays of analyte data and/or health information. In some implementations, the graphical displays are generating based on a self-referential dataset that are modifiable based on identified portions of the data. The modified graphical displays can indicate features in the analyte data of a host.

Abstract: Disclosed is a system and method for operating an imaging system. The imaging system may move or be moved to acquire image data of a subject at different positions relative to the subject. The image data may, thereafter, be combined to form a single image.

Abstract: Disclosed herein is an automated process of identifying shut-in parameters of a hydraulic fracturing operation from hydraulic fracturing treatment (HF) data. Also disclosed is a system and computer program product for automatically determining shut-in parameters from HF data. The HF data can be collected in real time during a HF from various sensors, equipment, or systems typically used in HFs or present at a well site. In one example, a method for automatically determining hydraulic fracturing parameters includes: (1) obtaining HF data, (2) determining a Rate Shut-In (RSI) time from the HF data, (3) determining a Well Shut-In (WSI) time using the RSI, and (4) calculating an Instantaneous Shut-In Pressure (ISIP) value based upon both the RSI and the WSI times, wherein determining the RSI time, the WSI time and calculating the ISIP value are automatically performed by one or more processors.

Abstract: An imidazoquinoline compound having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer is described.

Abstract: 5?-O-Phenylacetyluridine effectively delivers both phenylacetate and uridine to a subject. It can be used to treat hepatic encephalopathy and genetic disorders of the hepatic nitrogen cycle.

Abstract: An electronic pharmacy adjudication system and associated method and computer program product for performing adjudication service for a healthcare insurance claim is provided. The system includes an interface layer, an orchestration layer and a service and rules engine layer configured for receiving, processing and releasing an adjudication decision. The orchestration layer processes the healthcare insurance claim to generate a sequence of service calls to the service and rules engine layer to derive a sequence of partial decision results, which are derived by processing a set of parameters identified by the service call according to a corresponding subset of decisions rules in a rules repository. The sequence of partial decision results is then processed to derive the adjudication decision corresponding to the healthcare insurance claim.

Abstract: Anti-fogging apparatus and methods for protective eyewear which use air flow directed by designed nozzles to the surface of the lens of the protective eyewear are described. The established flow into the mask reduces or eliminates fogging on a lens of the mask. In some examples, air is directed into the interior protective area using nozzles that are positioned at particular angles relative to the lens. Said apparatus operates under particular configurations and with described methodology to improve anti-fogging ability while creating minimal disruption to the user's eyes.

Abstract: An electronic pharmacy adjudication system and associated method and computer program product for performing adjudication service for a healthcare insurance claim is provided. The system includes an interface layer, an orchestration layer and a service and rules engine layer configured for receiving, processing and releasing an adjudication decision. The orchestration layer processes the healthcare insurance claim to generate a sequence of service calls to the service and rules engine layer to derive a sequence of partial decision results, which are derived by processing a set of parameters identified by the service call according to a corresponding subset of decisions rules in a rules repository. The sequence of partial decision results is then processed to derive the adjudication decision corresponding to the healthcare insurance claim.

Abstract: A smoking article filter includes a recess to receive a filter insert unit. The filter insert unit is secured to the filter once inserted. The filter and the filter insert unit may include additives such as flavourants, colourants or sorbents.

Abstract: A smoking article filter includes a recess to receive a filter insert unit. The filter insert unit is secured to the filter once inserted. The filter and the filter insert unit may include additives such as flavourants, colourants or sorbents.

Abstract: A translating actuator acting between two extreme positions defined by mechanical stops is described. Said actuator comprises: an armature mass movable relative to the armature body, a stiff armature spring set such that the natural resting position of the armature mass is close to the centre of travel between the two extreme positions and pair of latches with sufficient holding force that the armature mass can be held at either extreme position against the restoring force of the spring and can be released quickly relative to the natural period of vibration determined by the armature mass on the armature spring.

Abstract: A system for power conversion and energy storage is described. In an embodiment the system comprise a DC rotating electrical machine (1) comprising a DC rotor; an AC rotating electrical machine (2) comprising an AC rotor; and a (thermo-) mechanical energy storage system (known as a TMESS) (3). The TMESS comprises a central shaft, said central shaft charged and discharged with shaft power and selectively mechanically coupled to the DC rotor and to the AC rotor via clutch (4) to form a shaft train. Some source of DC generation such as photovoltaic cells (5) feeds electrical power into the DC electrical machine (1). There may also be local DC loads (8) supported by the system. The AC electrical machine (2) may deliver power to local AC loads (6), or draw power from the AC electrical grid (7).

Abstract: Disclosed are compounds of general formula (I): and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.

Abstract: Disclosed are compounds of general formula (I): and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.