Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract: Systems and methods for optimizing the performance of a vehicle under normal operating conditions. A vehicle system adjusts one or more vehicle operating parameters in a closed-loop in response to data received from sensors. A portable vehicle communication interface module is selectively attached to the vehicle without inhibiting normal operation of the vehicle. When connected to the vehicle, the vehicle communication interface module records the adjustments made by the vehicle system in closed-loop operation. These recorded values are then used to update calibration information that the vehicle system uses as default values.

Abstract: This system creates a virtual image of the user's entire operating environment using a combination of hub speed, crank speed, inclination, and acceleration measurements. With this information, the system is able to understand the output torque and speed, and through control of the transmission, change the “gear ratio” to achieve a more desired operating condition based on the individual user's preferences. In addition, this system is designed to also work with a continuously variable transmission to avoid the shortfall of the state of the art systems, which can only get within a wide range of the optimal cadence because of the fixed ratios of a derailleur system.

Abstract: Systems and methods for optimizing the performance of a vehicle under normal operating conditions. A vehicle system adjusts one or more vehicle operating parameters in a closed-loop in response to data received from sensors. A portable vehicle communication interface module is selectively attached to the vehicle without inhibiting normal operation of the vehicle. When connected to the vehicle, the vehicle communication interface module records the adjustments made by the vehicle system in closed-loop operation. These recorded values are then used to update calibration information that the vehicle system uses as default values.

Abstract: A blood glucose measuring system which comprises a blood glucose (bG) meter and a portable communication device (PCD) and methods thereof are disclosed. The blood glucose meter comprises a measurement module and a wireless module, wherein the measurement module is operable to measure the blood glucose level of a blood sample, the wireless module is an embeddable module and communicates to the measurement module via a serial interface, and the wireless module is operable to wirelessly communicate to the portable communication device. The portable communication device is operable to wirelessly receive information from the blood glucose meter related to the blood glucose measurement.

Abstract: A display device which includes an elongate strip of sheet material having a plurality of product carrying pockets each pocket being provided with a pair of laterally spaced front sections in a plane substantially parallel to the plane of an adjacent rear section of the elongate strip, each front section being attached to the rear section at its upper edge respectively, by way of upper bridge portions, further attachment between a further section of the rear section and the front sections is provided by a lower bridge portion intermediate the front sections and which is attached adjacent the lower edges thereof.

Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract: Methods, manufactures, machines and compositions are described for nanotransfer and nanoreplication using deterministically grown sacrificial nanotemplates. An apparatus, includes a substrate and a nanoconduit material coupled to a surface of the substrate. The substrate defines an aperture and the nanoconduit material defines a nanoconduit that is i) contiguous with the aperture and ii) aligned substantially non-parallel to a plane defined by the surface of the substrate.

Abstract: In one aspect, the present invention provides a method of designing a diffractive ophthalmic lens (e.g., an intraocular lens (IOL)) that includes providing an optic having an anterior refractive surface and a posterior refractive surface, wherein the optic provides a far-focus power (e.g., in a range of about 18 to about 26 Diopters (D)). A truncated diffractive structure can be disposed on at least one of the surfaces for generating a near-focus add power (e.g., in a range of about 3 D to about 4 D). And the diffractive structure can be adjusted so as to obtain a desired distribution of optical energy between the near and far foci for a range of pupil sizes.

Abstract: A method of manufacturing a hardfaced plate (1) by applying a cladding (3) to a surface of a substrate (40) by arc welding, the method comprising moving the substrate (4) and a continuous arc welding wire feed (23) relative to each other, wherein the welding wire feed (23) is in a direction generally transverse to said given direction of relative movement. The welding wire can be fed by a welding gun (23) to the surface of the substrate (4) to be clad from one side of the given direction of relative movement at an acute angle to the surface of the substrate (40).

Abstract: Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Application Specific Integrated Circuit (OASIC). The microorganism is generally a bacterium.

Abstract: An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on the chip for processing the photocurrent. A distributed electrode configuration including a plurality of spaced apart electrodes disposed on an active region of the photodetector is preferably used to raise efficiency.

Abstract: In one aspect, the present invention provide an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior optical surface and a posterior optical surface, where the optic provides an optical power in a range of about 16 D to about 25 D as measured in a medium having an index of refraction substantially similar to that of the eye's aqueous humor (e.g., about 1.336). At least one of the optical surfaces is characterized by an aspherical base profile such that the optic exhibits a negative spherical aberration in a range of about ?0.202 microns to about ?0.190 microns across the power range.

Abstract: The present invention provides an ophthalmic lens (e.g., an intraocular lens) having an optic with an anterior surface and a posterior surface, which exhibits a shape factor (defined as a ratio of the sum of the anterior and posterior curvatures to the difference of such curvatures) in a range of about ?0.5 to about 4. In a related aspect, the shape factor of the optic lies in a range of about 0 to about 2. The above shape factors give rise to a plurality of different lens shapes, such as concave-convex, plano-convex and plano-concave.

Abstract: Aspheric diffractive lenses are disclosed for ophthalmic applications. For example, multifocal intraocular lens (IOLs) are disclosed that include an optic having an anterior surface and a posterior surface, at least one of which surfaces includes an aspherical base profile on a portion of which a plurality of diffractive zones are disposed so as to generate a far focus and a near focus. The aspherical base profile enhances image contrast at the far focus of the lens relative to that obtained by a substantially identical IOL in which the respective base profile is spherical.

Abstract: The present invention provides an intraocular lens (IOL) having an optic with a posterior and an anterior refractive surfaces, at least one of which has an aspherical profile, typically characterized by a non-zero conic constant, for controlling the aberrations of a patient's eye in which the IOL is implanted. Preferably, the IOL's asphericity, together with the aberrations of the patient's eye, cooperate to provide an image contrast characterized by a calculated modulation transfer function (MTF) of at least about 0.25 and a depth of field of at least about 0.75 Diopters.

Abstract: There is disclosed a system and method of formulating a batch comprising at least two ingredients. An embodiment is disclosed wherein a feedforward algorithm can be used to control the target blend. Subsequently a feedback closed loop control loop algorithm is provided for a multivariant blend. Use of this approach allows for a continuously autoreplenished and controlled blend. Another enhancement disclosed is the ability to control via feedforward and feedback algorithms a fast responding control mode which allows for the elimination of a tank. This approach will allow for “one pass” blending with control. Feedback control can be provided via process indicators or through analytical or parametric methods. The controller implements an automated fault detection and correction system, thereby identifying necessary maintenance prior to failure. If failure does occur the signature recognition allows rapid analysis and correction thus maximizing tool availability.

Abstract: Systems and methods are described for individually electrically addressable carbon nanofibers on insulating substrates. A method includes forming an electrically conductive interconnect on at least a part of an insulating surface on a substrate; and growing at least one fiber that is coupled to the electrically conductive interconnect.

Abstract: The present invention provides anti-microbial foam dispensing hand-sanitizer devices. The devices provide ease and convenience of use, require no water for use, and have improved residue reduction. Also provided are kits and methods of use.

Abstract: Methods, manufactures, machines and compositions are described for nanotransfer and nanoreplication using deterministically grown sacrificial nanotemplates. A method includes depositing a catalyst particle on a surface of a substrate to define a deterministically located position; growing an aligned elongated nanostructure on the substrate, an end of the aligned elongated nanostructure coupled to the substrate at the deterministically located position; coating the aligned elongated nanostructure with a conduit material; removing a portion of the conduit material to expose the catalyst particle; removing the catalyst particle; and removing the elongated nanostructure to define a nanoconduit.