Abstract: The invention relates to a device for reducing the microbiological contaminants of container products which consist predominantly of plastics materials. In said device a plastics granulate is fed to an extruder assembly (19) which melts the granulate, said granulate being subsequently supplied to a form fill seal machine for producing the relevant container product. The device also comprises a guide assembly (35) for the targeted guidance of the plasticated plastics material from the extruder assembly (19) to said machine. The device is characterised in that at least one guide assembly (35) has at least one flow or channel guide (41) for the melted plastics material, so that microbiological contaminants are guided predominantly into the interior of the wall of the polymeric tube, said interior being enclosed by regions of the plastics material that are less contaminated.

Abstract: The invention relates to a plastic container product, in particular produced by the blow-molding, filling, and sealing method, having a container wall which can be pierced by means of a cannula in predefinable areas for the purpose of access to the container content. Said plastic container product is characterized in that, in order to avoid punched parts which arise when the container wall is pierced with a cannula, the mathematical product of the container wall thickness in the piercing area and the tensile modulus of the plastic material to ISO 527 is less than 400 MPa·mm, in particular preferably less than 300 MPa·mm.

Abstract: A transfer system for containers comprises at least a first (1) and at least a second container (5), which can be interconnected in a media-transferring way by a connection system (7). Said connection device has a transfer device (27) which, held in a locked position by means of at least one locking device (25), prevents an exchange of media or permits said exchange in at least one unlocked position in which the transfer device (7) is guided longitudinally movably in a seat (9) of the connection device (7) for a transfer operation, the locking device (25) being transferable to an unlocked position by the movement of at least one of the containers (5). Said transfer system is characterized in that additional control means (13, 21) are present on the respective movable container (5) and at least partially enclose the outer periphery of this container (5) and actuate the locking device (25) of the transfer device (27) to unlock.

Abstract: The invention relates to a plastic container product, in particular produced by the blow-molding, filling, and sealing method, having a container wall which can be pierced by means of a cannula in predefinable areas for the purpose of access to the container content. Said plastic container product is characterized in that, in order to avoid punched parts which arise when the container wall is pierced with a cannula, the mathematical product of the container wall thickness in the piercing area and the tensile modulus of the plastic material to ISO 527 is less than 400 MPa·mm, in particular preferably less than 300 MPa·mm.

Abstract: A transfer system for containers comprises at least a first container (1) and at least a second container (5) which can be interconnected in a media-transferring way by a connection system (7), and is characterized in that an encryption system (13, 21, 25, 31) is provided in order to allow or prevent a media-transferring connection between the respective assignable containers (1, 5).

Abstract: The invention relates to a container having a head piece (7), which container can be or is filled with a medium and is produced of plastic materials using a blow molding, filling, and sealing method, comprising a transition region (13) between the container (1) and at least one first type of a head surface (11), which is arranged on the head piece (7) at an end face and can be penetrated by means of a piercing or cutting part and extends with a specifiable curvature. Said container is characterized in that at least one second type of a head surface (41), which likewise has a specifiable. curvature, which is the same as the curvature of the head surface (39) of the first type, but preferably is different therefrom, is present on the head piece (7), that the head surfaces transition into each other in such a way that a whole surface is formed, which spans the free end of the transition region (13) directed away from the container (1), and that the head piece (7) is an integral component of the container (1).

Abstract: 1. Dispensing device. 2.

Abstract: The invention relates to a container, in particular a plastic ampoule which is produced using a blow moulding process, and which is filled and closed in the production mould, said container having a sleeve-type neck part (4) connected to a container body (2) as an axial extension, said neck part forming a seat (6) for a pre-formed insert (8) extending along the axis (12) of the neck part (4), and said neck part being formed in the production mould, on a peripheral region (14) of the insert (8), characterised in that at least one sealing element (42; 68) is provided on the insert (8), said sealing element forming a seal in a sealing region surrounding the axis (12), in combination with a contact surface (38) formed on the seat (6) of the neck part (4).

Abstract: The invention relates to a device for producing at least one container product made of plastics material, which is molded by means of a molding device (1), provided with a predefinable container content by means of a filling device and closed by means of a closing device, characterized in that the respective finished container product is fed to a post-treatment zone in which the respective container product and/or the respective container content is subjected to a temperature-influencing effect.

Abstract: A container, in particular a plastic vial produced in the blow-moulding method and filled and closed in the mould, comprising a neck part (5) joining a container body (1), onto which neck part a one-part or multi-part cap (2) can be placed, in particular slipped, a fixing part (29) being associated with the cap (2), which fixing part is connected to the cap (2) by means of at least one predetermined breaking point (31), which can be detached by a relative rotational motion between the cap (2) and the Container body (1) or parts of the Container body, is characterized in that each predetermined breaking point (31) can be detached by rotational motions that occur both in the one rotational direction and in the other rotational direction with approximately the same angle of rotation and approximately the same torque.

Abstract: A sealing arrangement consisting of at least one container (1) and/or at least one container part, such as a closure cap placed onto the container (1), wherein the interior of the container (1) is used to accommodate a medium, particularly a fluid bottled in a sterile manner, which can be removed from the container (1) by means of a removal device such as a syringe needle, which removal device to this end penetrates at least one sealing material (9), which sealing material is connected to the container (1) and/or parts thereof. Said sealing arrangement is characterised in that the respective sealing material (9) is arranged on the outside (7) of the container (1) and/or container parts thereof facing the environment and that the respective sealing material (9) is fixedly connected to the outside (7) of the container (1) and/or container parts thereof facing the environment by means of a fused and/or adhesively bonded connection.

Abstract: The invention relates to inhalant propellant-free aerosol formulations containing at least one inert, non-volatile auxiliary substance for adjusting defined droplet sizes.

Abstract: A medicine dispensation device, in particular a multi-dose powder inhalator, for the dispensing of individual doses of medicine that has a number of medicine chambers contained in a medicine magazine shaped like a continuous loop. The medicine chambers form groups in such a manner that a mouthpiece reaches the different groups by an essentially complete rotation of the medicine magazine. This enables several medicine chambers—typically one, two or three—to be situated between two successive intake positions, which allows for a high density of medicine chambers and thus creates an inhalation device, which can be handled comfortably even when containing a great number of individual doses.

Abstract: An atomizer and a method of dispensing and atomizing fluid into individual containers through a nozzle are proposed, where in order to improve the dosing accuracy, a preliminary amount of fluid, flushing the nozzle, is dispensed before each dose is dispensed.

Abstract: The invention relates to inhalant propellant-free aerosol formulations containing at least one inert, non-volatile auxiliary substance for adjusting defined droplet sizes.

Abstract: The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches (2) for holding a medicament are formed as depicted in exemplary FIG. 1. The foil strip comprises for transporting the strip openings (4) on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.

Abstract: A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5?) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.

Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.

Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.

Abstract: A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5?) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.