Abstract: The invention is a medicament magazine having at least one medicament chamber for use in a powder inhaler, wherein the magazine is formed from two foil strips applied to one another and the at least one medicament chamber is formed between the foil strips as depicted in exemplary FIGS. 1a and 1b. The medicament chambers have an internal structure (3) which comprises in its interior a space for receiving a powdered medicament and stabilizes this inner space against external mechanical influences. In another embodiment in which the internal structure preferably also has a stabilizing function, the structure has means for opening one foil strip. In addition, the medicament chamber contains a retaining device which holds the internal structure on the medicament magazine after the medicament chamber has been opened.

Abstract: The invention relates to a method for filling a capsule with a pharmaceutical active-substance formulation, wherein the capsule consists of two capsule parts (a capsule body and a capsule cap) and the two capsule parts, without being previously interlocked when empty, are only fitted together in a telescopic manner once one capsule part has been filled with a pharmaceutical active-substance formulation, as well as a device for this purpose.

Abstract: The invention relates to a method for sterilizing a film container for holding articles, foods, cosmetics, medical implants, medical plasters, medical auxiliaries, microbiological tools or a pharmaceutical active substance formulation, a method for testing the leaktightness of a film container sterilized by electron radiation or gamma radiation, and a film container for use in the methods.

Abstract: Atomizers (1) comprising a cartridge holder (4) which is arranged in the housing (3), a mouthpiece (5) which is provided on the housing (3) and in which an atomization device (6) is arranged, and a connecting tube system (7) which connects the atomization device (6) and the cartridge holder (4), wherein the atomization device (6) has at least one nozzle body (8) and the connecting tube system (7) has at least one passage (9) with a hollow plunger (10) mounted displaceably therein, wherein the hollow plunger (10) includes a valve body (21). In accordance with a first embodiment the atomizer (1) has a first hollow plunger (10a) mounted displaceably in a first passage (9a) and a second hollow plunger (10b) mounted displaceably in a second passage (9b), wherein the first hollow plunger (10a) and the second hollow plunger (10b) extend into the cartridge holder (4).

Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.

Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.

Abstract: The invention relates to aqueous aerosol preparations for inhalation, containing therapeutically active micro-organisms or parts of micro-organisms as the active ingredient.

Abstract: An inhaler for propellant-free atomization of a medicament preparation. The inhaler produces an aerosol at low speed. The inhaler is combined with an add-on device for intermediate storage of the aerosol produced, so as to allow easier inhalation, particularly for children.

Abstract: The invention is a medicament magazine having at least one medicament chamber for use in a powder inhaler, wherein the magazine is formed from two foil strips applied to one another and the at least one medicament chamber is formed between the foil strips. The medicament chambers have an internal structure (3) which comprises in its interior a space for receiving a powdered medicament and stabilises this inner space against external mechanical influences. In another embodiment in which the internal structure preferably also has a stabilising function, the structure has means for opening one foil strip. In addition, the medicament chamber contains a retaining device which holds the internal structure on the medicament magazine after the medicament chamber has been opened.

Abstract: The invention relates to inhalant, propellant-free aerosol formulations containing ethanol, said formulations having defined particle size distribution sizes.

Abstract: The invention relates to inhalant propellant-free aerosol formulations containing at least one inert, non-volatile auxiliary substance for adjusting defined droplet sizes.

Abstract: The invention concerns a medicine dispensation device, in particular a multi-dose powder inhalator, for the dispensing of individual doses of medicine as depicted in exemplary FIG. 1. Therein a number of medicine chambers are contained in a medicine magazine shaped like a continuous loop. The medicine chambers form groups in such a manner that a mouthpiece reaches the different groups by an essentially complete rotation of the medicine magazine. This enables several medicine chambers—typically one, two or three—to be situated between two successive intake positions, which allows for a high density of medicine chambers and thus creates an inhalation device, which can be handled comfortably even when containing a great number of individual doses.

Abstract: The invention relates to a medicament dispensing device, particularly a multi-dose powder inhaler, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine as depicted in exemplary FIG. 1. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5?) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.

Abstract: An atomizer (1) and a method of dispensing and atomizing fluid (2) into individual containers through a nozzle (12) are proposed. To improve the dosing accuracy, a preliminary amount of fluid (2), flushing the nozzle (12), is dispensed before each dose is dispensed.

Abstract: The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches (2) for holding a medicament are formed. The foil strip comprises for transporting the strip openings (4) on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.

Abstract: The invention relates to the first-time filling of a liquid conducting system in an inhaler. According to the invention, a pressure that is built up in the reservoir by mounting the closure thereupon is released when the reservoir is inserted into the inhaler so as to displace liquid from the reservoir by means of the liquid conducting system such that the dead volume of the liquid conducting system is filled with liquid and the nozzle is connected in an air-free manner to the liquid store.

Abstract: Atomizers (1) comprising a cartridge holder (4) which is arranged in the housing (3), a mouthpiece (5) which is provided on the housing (3) and in which an atomization device (6) is arranged, and a connecting tube system (7) which connects the atomization device (6) and the cartridge holder (4), wherein the atomization device (6) has at least one nozzle body (8) and the connecting tube system (7) has at least one passage (9) with a hollow plunger (10) mounted displaceably therein, wherein the hollow plunger (10) includes a valve body (21). In accordance with a first embodiment the atomizer (1) has a first hollow plunger (10a) mounted displaceably in a first passage (9a) and a second hollow plunger (10b) mounted displaceably in a second passage (9b), wherein the first hollow plunger (10a) and the second hollow plunger (10b) extend into the cartridge holder (4).

Abstract: A metering receptacle has an elongate hollow body which at one end has a closable exit opening, and which at the other end is closable by way of a plastic plunger stopper. The plunger stopper is at the same time longitudinally displaceable in the hollow body by way of a plunger rod. The metering receptacle is configured such that the plunger stopper is formed of two parts, with a sealing stopper part of plastic which is rigidly positionable in the elongate hollow body and has a centric bore for the passage of the plunger rod, and with a longitudinally displaceable plunger part of lubricious plastic which is connected to the plunger rod.

Abstract: The present invention relates to a new pharmaceutical blister with reduced permeability to water vapor and gas. It is proposed according to the invention to coat conventional blisters with a silicon oxide-containing functional layer to protect against gases, water vapor and organic molecules.

Abstract: The device for transporting, filling and sterilizing medicinal containers (3) includes a rigid foamed plastic carrier plate (1) provided with a plurality of first openings (2) for receiving the respective containers (3). The first openings have respective open cross-sections adapted to corresponding cross-sections of the containers and the rigid carrier plate (1) has a predetermined thickness, so that the containers (3) are clamped and held fixed in position relative to the carrier plate and centered in the first openings (2) without rattling so that no scratch marks and/or no static charges are produced on the medicinal containers (3) during transport. The rigid foamed plastic carrier plate (1) is provided with a pore-free sealed surface that facilitates sterilization. Second openings (20), which are smaller than the first opening (2) and cannot receive the containers, are also provided in the carrier plate to facilitate sterilization in an autoclave.