Abstract: Such receptacles are integrated or may be integrated with pressure means and at the exit-side end (2) comprise a closable exit opening (3) for the liquid medical substance filled in the receptacle. With known receptacles the exit opening (3) is difficult to close in a germ-tight and fluid tight manner. Furthermore a relatively high pressure must be exerted on the medically effective substance in order to penetrate all skin layers of the patient. For avoiding these disadvantages the invention envisages integrally forming a hollow-spike-like continuation (5) of a predetermined length corresponding to the thickness of the dermis of the human being at the exit side end (2), said continuation comprising the exit opening (3) and extending the exit channel. A conventional closure cap may be placed in a simple manner on this continuation (5) in a fluid-tight and germ-tight manner.

Abstract: The glass container stores and preserves pharmaceutical or diagnostic solutions for medicinal purposes. So that the container is free of silicones and other residues, it is provided with an amorphous, transparent anti-adherent coating (4) over its entire interior surface from its bottom over the wall (3) to the closure device (2). This anti-adherent coating (4) is free of heavy metals, free of silicones, is stable after autoclaving at about 120° C. for about 20 min or hot air sterilization for 30 min at 300° C., has a contact angle for wetting with water of ≧80°, contains silicon, oxygen, carbon, fluorine and hydrogen and is deposited by a PECVD method, especially a PICVD method. If the coating contains less than 0.1% by weight fluorine, then it contains greater than or equal to 10% by weight carbon, but if it contains greater than or equal to 0.1% fluorine then it contains greater than or equal to 5% by weight carbon.

Abstract: The glass container stores and preserves pharmaceutical or diagnostic solutions for medicinal purposes. In order to provide a silicone-free but residue free bottle after emptying, the glass container is provided with an amorphous transparent and pharmaceutically acceptable anti-adherent coating (4) over the entire interior surface of the glass container from its bottom over the wall (3) to the closure device (2). This anti-adherent coating (4) has a contact angle for wetting with water of ≧80°, even after autoclaving at about 120° C. for about 20 min, contains silicon, oxygen, carbon and hydrogen and is deposited according to a PECVD method, especially a PICVD method.

Abstract: The process for applying a thermally attached lubricating coating on an interior wall of a cylindrical medicinal container includes applying a thermally attachable lubricant to an interior wall of the container; uniformly spreading or homogenizing the applied lubricant on the wall to form a lubricating coating and thermally attaching the lubricating coating by irradiating the lubricating coating with infrared radiation selectively in a cylindrical region of the container at elevated temperatures above a maximum operating temperature of the container. The apparatus for performing the process includes an insertable spraying device for applying the thermally attachable lubricant (3) to the interior wall of the container (1) from a supply reservoir; a device for homogenizing the lubricant to form the lubricating coating (4) and a rod-shaped infrared radiation source (5) insertable into an interior space of the container.

Abstract: The improved glass container for freeze-dried products includes a casing section (1) with a bottom portion (3) and an outlet portion (2). The casing section (1) is thin-walled in comparison to the bottom portion (3) and the outlet portion (2) is formed so as to be closable by a closure device. The bottom portion (3) has a nonuniform geometry and is provided with at least one interior depression (3b), a reinforced section (3a) and an outer bottom surface (3o) that is completely planar or planar with a comparatively slight central indentation (3c) but with a sufficient contact area for a cooling plate used in freeze-drying. The structure of the bottom portion guarantees a uniform crystalline lyophilizate structure. The glass container has a very low breakage rate and can be nearly completely emptied.

Abstract: Glass containers specifically for the storage of pharmaceutical or diagnostic solutions whose surface which comes into contact with the solutions is coated with a layer of oxides and/or nitrides of the elements Si, Ti, Ta, Al or mixtures thereof applied by means of a plasma CVD process.

Abstract: A cap of a closure arrangement of a prefilled disposable syringe is only removed in advance of utilizing the syringe. The disposable syringe has a syringe body (2, 3) and an injection needle (4) integrated in this body. The closure arrangement includes a stiff plastic cap (5) pushed onto the syringe head (2) and includes a lining (6) in the interior thereof which seals the needle tip. In another syringe type without integrated needle, a connecting cone of a conical connection is formed on the syringe body. The closure arrangement includes an elastomeric closure cap (tip-cap) seated on the connecting cone. The closure cap is covered by a stiff plastic cap connected to the syringe body. In both types of disposable syringes, the plastic cap is welded or cemented while forming a desired break location (7) with the syringe body (2, 3).

Abstract: The improved container for liquid and solid medicinal preparations, especially freeze-dried products, includes a casing section (1) with a bottom portion (3) and an outlet portion (2). The casing section (1) is thin-walled in comparison to the bottom portion (3) and the outlet portion (2) is formed so as to be closable by a closure device. The bottom portion (3) has a nonuniform geometry and is provided with at least one interior depression (3b), a reinforced section (3a) and an outer bottom surface (3o) that is completely planar or planar with a comparatively slight central indentation (3c). The container is lightweight and stable which guarantees a uniform lyophilizate structure. In the case of a glass container the container of the invention has a very low breakage rate and can be nearly completely emptied.

Abstract: The syringe for transferring a medical substance from a container (10) provided with an elastomeric closure into an infusion container has a plastic syringe body (1). In order to avoid the danger of injury to a user by medical hollow needles previously used on syringes, a plastic hollow peg (9) is arranged at the front end of the plastic syringe body (1) instead of the typical sharp hollow needle. However the plastic hollow peg (9) is formed so that it can pierce the elastomeric closure (11) of the container (10). The hollow peg (9) is preferably in one piece with the syringe body (1). A transfer arrangement including a syringe (1), a preparation container (10) and a holder (10a) that holds the syringe on the preparation container is also described.

Abstract: This invention relates to optical, preferably ophthalmic lenses with a body made of plastic, in particular for spectacle glasses, and the plastic incorporates cycloolefinic polymers and the plastic body is coated with a transparent coating resistant to corrosion. Another object of this invention is a process for the production of these lenses. The lenses according to the invention are especially resistant to greases, sweat and/or solvents.

Abstract: The process for applying a thermally attached lubricating coating on an interior wall of a cylindrical medicinal container includes applying a thermally attachable lubricant to an interior wall of the container; uniformly spreading or homogenizing the applied lubricant on the wall to form a lubricating coating and thermally attaching the lubricating coating by irradiating the lubricating coating with infrared radiation selectively in a cylindrical region of the container at elevated temperatures above a maximum operating temperature of the container. The apparatus for performing the process includes an insertable spraying device for applying the thermally attachable lubricant (3) to the interior wall of the container (1) from a supply reservoir; a device for homogenizing the lubricant to form the lubricating coating (4) and a rod-shaped infrared radiation source (5) insertable into an interior space of the container.

Abstract: A metering receptacle has an elongate hollow body which at one end has a closable exit opening, and which at the other end is closable by way of a plastic plunger stopper. The plunger stopper is at the same time longitudinally displaceable in the hollow body by way of a plunger rod. The metering receptacle is configured such that the plunger stopper is formed of two parts, with a sealing stopper part of plastic which is rigidly positionable in the elongate hollow body and has a centric bore for the passage of the plunger rod, and with a longitudinally displaceable plunger part of lubricious plastic which is connected to the plunger rod.

Abstract: Syringes for medical purposes have syringe bodies which typically have a syringe body (2) on which a syringe head (3) is formed at the outlet end. A finger support (1) is at the other end. This finger support has an enlarged support surface in two mirror-symmetrical opposite-lying regions. To increase the support surface further, the finger support (1) is so configured that the two regions (1a, 1b) have a parabola-shaped configuration whose respective apexes are directed away from the syringe body (2). The two regions go over one into the other in the region (1c, 1d) of the mirror axis in an arcuate shape. In this way, the ergonomic manipulation of the syringes is improved and a high packing density of the syringes when magazining is made possible.

Abstract: The device for transporting medicinal containers includes a rigid plastic carrier plate (1) provided with a plurality of openings (2) for receiving the respective containers (3). The openings have respective open cross-sections adapted to corresponding cross-sections of the containers and the carrier plate (1) has a predetermined thickness, so that the containers (3) are held fixed and centered in the openings (2) without vibrating or rattling and so that no scratch marks are produced on the medicinal containers (3) during transport. Preferred embodiments include collars around the openings projecting from the carrier plate, especially to securely hold syringes with finger supports resting on the collars, tapering conical openings with a narrow portion and/or annular projections within the openings to engage and hold the containers.

Abstract: Prefilled, disposable syringes for injecting preparations with a fill volume of less than 5 ml are typically made of glass. The disposable syringe in this invention avoids the use of glass as a construction material. The body of the syringe with barrel, grip and nozzle is made of transparent, glass-like plastic with a very low gas permeability and is designed to be resistant to gamma rays and/or ethylene oxide gas, whereby the hypodermic needle is directly integrated within the plastic nozzle.

Abstract: The pharmaceutical packing device has a hollow plastic body (1) of axial length (I) and a cylindrical portion (7) extending over at least a part of its axial length and an interior silicone lubricant layer (3) provided on an interior surface of the plastic body in the cylindrical portion (7). The lubricant layer (3) provides a sliding surface for a flexible piston (4) slidably mounted in the hollow plastic body, thus forming an injector device. The silicone lubricant layer (3) is made by a method including preparing a mixture of reactive silicone oil and non-reactive silicone oil, applying this mixture to the interior surface at a temperature of at least 40° C. in a single step without activation of the surface to form a preliminary layer and cross-linking the reactive silicone oil in the preliminary layer to form the silicone lubricant layer.

Abstract: The invention concerns a container for injection, infusion, and diagnostic preparations, serving, on the one hand, as a long-term storage container, and, on the other, as a device for directly dispensing the preparations. The container has a glass barrel with a glass headpiece with a connector cone that acts as a nozzle. This is molded onto a glass barrel, thereby forming a single unit. A separate plastic, threaded section of an interlocking, conical joint is mounted onto the connector cone, accommodating a secured sealing cap that can be removed from the connector cone. The other opening of the glass barrel is sealed by a plunger that has a connection spot for a plunger rod. Furthermore, the container has a plastic grip mounted onto the inner wall of the glass barrel. Since the container, including the external profile, is, on the whole, designed to resemble a standard syringe, it ensures that the invented container can be accommodated by all current syringe pumps.

Abstract: The pharmaceutical packing device has a hollow plastic body (1) of axial length (1) and a cylindrical portion (7) extending over at least a part of its axial length and an interior silicone lubricant layer (3) provided on an interior wall of the plastic body in the cylindrical portion (7). The lubricant layer (3) provides a sliding surface for a flexible piston (4) slidably mounted in the hollow plastic body, thus forming an injector device. The silicone lubricant layer (3) is a mixture of a reactive silicone oil with a non-reactive silicone oil according to the invention. This lubricant layer is provided in a one-step method in a simple manner. Especially this method avoids or minimizes the amount of droplets of silicone oil fed into the contents of the hollow plastic body (1).

Abstract: The invention consists of a glass bottle (1) fitted with a narrowed neck (2) which can be filled under pressure with chiefly a medically active substance sprayable by aerosol and with a propellant and which exhibits an opening which may be closed using a dosage valve (5). This glass bottle (1) has a sprayed on synthetic coating (4) to protect it against shattering and splintering, preventing the user from being injured by the broken bottle. To substantially enhance this safety, the neck (2) of the bottle (1) has been fitted with a bulge like edge (3) at the opening which is also coated with the synthetic material (4) and onto which the dosage valve (5) is mechanically attached by turning. Furthermore, the coating (4) consists of an elastic synthetic material with pronounced increased shrinkage properties used for the summoning of pre-stressing force on the glass body (1) and it exhibits several hole like pressure relieving openings (7) permitting rapid pressure release in case of shattering.

Abstract: The piston burette for storing and dispensing a reagent used in analytical or metering work includes a calibrated burette cylinder (11) and a piston (13) slidably mounted in it.