Patents by Inventor Muraleedharan G. Nair

Muraleedharan G. Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10531662
    Abstract: Compounds and compositions are described herein that inhibit the biosynthesis of mycotoxins and fungal sporulation. Such compounds and compositions are useful for inhibiting mold. Methods of using such compounds and compositions are also described herein that involve applying the compositions to plants, plant parts, structures, containers, and other surfaces.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: January 14, 2020
    Assignees: Board of Trustees of Michigan State University, Sokoine University of Agriculture
    Inventors: Gale M. Strasburg, Juma A. Mmongoyo, John E. Linz, Felicia Wu, Jovin K. Mugula, Amila A. Dissanayake, Chuan-Rui Zhang, Josephine M. Wee, Muraleedharan G. Nair, Devin M. Day
  • Publication number: 20180192648
    Abstract: Compounds and compositions are described herein that inhibit the biosynthesis of mycotoxins and fungal sporulation. Such compounds and compositions are useful for inhibiting mold. Methods of using such compounds and compositions are also described herein that involve applying the compositions to plants, plant parts, structures, containers, and other surfaces.
    Type: Application
    Filed: January 8, 2018
    Publication date: July 12, 2018
    Inventors: Gale M. Strasburg, Juma A. Mmongoyo, John E. Linz, Felicia Wu, Jovin K. Mugula, Amila A. Dissanayake, Chuan-Rui Zhang, Josephine M. Wee, Muraleedharan G. Nair, Devin M. Day
  • Publication number: 20130209441
    Abstract: A process is provided for inhibition of neural damage associated with an ischemic event that includes the administration of anthocyanin compound to a subject. After allowing sufficient time for the anthocyanin compound to reach the situs of the ischemic event, inhibition of neural damage associated with the ischemic event occurs. Neural damage is further inhibited by administration of the anthocyanin compound in conjunction with an agent effective in and specifically including tissue plasminogen activator. The anthocyanin compound in specific embodiments is in pure form or a mixture of two or more anthocyanins, or anthocyanidins or aglycones thereof, with the mixture being a natural product extract. A composition is also provided that includes ananthocyanin compound to cause blood clot dissolution. The agent being in specific embodiments is tissue plasminogen activator or aspirin.
    Type: Application
    Filed: May 10, 2012
    Publication date: August 15, 2013
    Inventors: Muraleedharan G. Nair, Jiangyong Min, Arshad Majid
  • Patent number: 8337914
    Abstract: The present invention describes food supplements that contain one or more fruit extracts useful for pain relief and anti-inflammation. The food supplements may be used to inhibit inflammation mediated by cyclooxygenase and more particularly by cyclooxygenase-2.
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: December 25, 2012
    Assignees: Access Business Group International LLC, Michigan State University
    Inventors: Muraleedharan G. Nair, David L. Dewitt, Haibo Wang, David W. Krempin, Dipak K. Mody, David G. Groh, Mary A. Murray, Marc Lemay, Yong Qian, Audra J. Davies, Robin Dykhouse
  • Publication number: 20120283203
    Abstract: A process of enhancing insulin excretion in a subject includes administering to the subject a polyphenol active ingredient. The polyphenol active ingredient is a purified cyanidin-3-glycoside alone or purified cyanidin alone. The pharmaceutically acceptable carrier is administered with the polyphenol active ingredient.
    Type: Application
    Filed: April 30, 2012
    Publication date: November 8, 2012
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • Patent number: 8198249
    Abstract: A process of enhancing insulin excretion in a subject includes administering to the subject a polyphenol active ingredient. The polyphenol active ingredient is a purified cyanidin-3-glycoside alone or purified cyanidin alone. The pharmaceutically acceptable carrier is administered with the polyphenol active ingredient.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: June 12, 2012
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • Publication number: 20110003762
    Abstract: A process of enhancing insulin excretion in a subject includes administering to the subject a polyphenol active ingredient. The polyphenol active ingredient is a purified cyanidin-3-glycoside alone or purified cyanidin alone. The pharmaceutically acceptable carrier is administered with the polyphenol active ingredient.
    Type: Application
    Filed: May 4, 2010
    Publication date: January 6, 2011
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • Patent number: 7772195
    Abstract: A method for the treatment of obesity, diabetes, high cholesterol and related diseases including hyperglycemia, lipid disorders, hyperglyceridemia, dyslipidemia and atherosclerosis in mammals using anthocyanins, anthocyanidins, ursolic acid and/or betulinic acid is described. Compositions adapted for these treatments are also described.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: August 10, 2010
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • Patent number: 7737121
    Abstract: A method for stimulating insulin secretion by anthocyanidins and anthocyanins is described. The secretion can be in vivo in mammals, including humans, or in vitro.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: June 15, 2010
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, L. Karl Olson, Shaiju K. Vareed
  • Patent number: 7658937
    Abstract: A process for the preparation of hydroxyl substituted anthraquinones is described. The process couples a phthalic anhydride (substituted or unsubstituted) to benzene ring moiety substituted with at least two hydroxyl groups. Remaining hydroxy groups were converted to methoxy groups in some anthraquinones. The compounds are particularly useful for the treatment of parasitic diseases. Also, a method of treating or preventing malaria, filariasis schistosomiasis and other parasitic diseases using anthraquinones.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: February 9, 2010
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Mugunthu R. Dhananjeyan, Michael A. Kron, Youli P. Milev
  • Publication number: 20090018211
    Abstract: A method for inhibiting of COX2 and inflammation by administering a hydroxybenzaldehyde.
    Type: Application
    Filed: July 9, 2007
    Publication date: January 15, 2009
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Mulabagal Vanisree, Ruby L. Alexander-Lindo, David L. DeWitt
  • Patent number: 7341747
    Abstract: A composition for the treatment of onychomycosis (fungal nail disease) is described. The composition consists essentially of thymol, camphor, menthol and Eucalyptus citridiora as a colorless liquid oil without any carrier or solvent for these ingredients.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: March 11, 2008
    Assignee: Board of Trustees of Michigan State University
    Inventor: Muraleedharan G. Nair
  • Patent number: 7282593
    Abstract: Novel isolated and purified withanamides and withanolides are described. In particular, compounds from Withania somnifera fruit are the preferred source of the withanamides and withanolides, although they can be from other plant sources. In addition to their use as powerful antioxidants, the withanamides and withanolides can be useful for the treatment of depression, Alzheimer's Disease, obesity and migraine headaches.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: October 16, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Patent number: 7270836
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 18, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Patent number: 7264831
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 4, 2007
    Assignee: Board of Trustees of Michigan State Univeristy
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Patent number: 7264832
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 4, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Patent number: 7264833
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 4, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Patent number: 7211277
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: May 1, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Patent number: 7208182
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: April 24, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Patent number: 7195784
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: March 27, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam