Patents by Inventor Muraleedharan G. Nair

Muraleedharan G. Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6576271
    Abstract: A method for inhibiting cyclooxygenase enzymes and inflammation in a mammal using a cherry or cherry anthocyanins, bioflavonoids and phenolics is described. In particular a mixture including the anthocyanins, the bioflavonoids and the phenolics is described for this use.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: June 10, 2003
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Haibo Wang, Gale M. Strasburg, Alden M. Booren, James I. Gray
  • Patent number: 6423365
    Abstract: A method for isolating a mixture of anthocyanins, bioflavonoids and phenolics from cherries using adsorbent resins which are regenerable for reuse is described. The mixture with a consumable carrier is particularly useful in foods and as a dietary supplement or neutraceutical product.
    Type: Grant
    Filed: May 24, 1999
    Date of Patent: July 23, 2002
    Assignee: Board of Trustees of Michigan State University
    Inventor: Muraleedharan G. Nair
  • Patent number: 6361785
    Abstract: Compositions for the treatment of fungal nail disease (onychomycosis), including camphor, menthol, eucalyptus and thymol are described. The ingredients are natural and very effective in treating the nail fungus.
    Type: Grant
    Filed: September 6, 2000
    Date of Patent: March 26, 2002
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Russel S. Ramsewak, Sharon K. King, Manfred Stommel, Louise C. Selanders
  • Patent number: 6348193
    Abstract: A method for controlling bacterial fungal diseases using Pseudomonas aureofaciens in admixture with metabolites, particularly phenazine-1-carboxylic acid (PCA) is described. Pseudomonas aureofaciens is particularly useful in inhibiting the microorganisms in cultivated dicot plants, cereal crops and nursery stock and seeds. The method is environmentally safe and economical.
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: February 19, 2002
    Assignee: Board of Trustees of Michigan State University
    Inventors: Alvin Ronald Detwiler, Joseph M. Vargas, Jr., Nancy M. Dykema, Muraleedharan G. Nair
  • Patent number: 6344190
    Abstract: Compositions for the treatment of fungal nail disease (onychomycosis), including camphor, menthol, eucalyptus and thymol are described. The ingredients are natural and very effective in treating the nail fungus.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: February 5, 2002
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Russel S. Ramsewak, Sharon K. King, Manfred Stommel, Louise C. Selanders
  • Publication number: 20010020009
    Abstract: A method for inhibiting cyclooxygenase enzymes and inflammation in a mammal using a cherry or cherry anthocyanins, bioflavonoids and phenolics is described. In particular a mixture including the anthocyanins, the bioflavonoids and the phenolics is described for this use.
    Type: Application
    Filed: December 28, 2000
    Publication date: September 6, 2001
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Haibo Wang, Gale M. Strasburg, Alden M. Booren, James I. Gray
  • Publication number: 20010016573
    Abstract: A method for inhibiting a tumor in a mammal using a composition comprising an anthocyanin or cyanidin from a berry is described. The method involves using the composition in an amount and for a time to inhibit the tumor. The composition can include other antitumor agents.
    Type: Application
    Filed: February 2, 2001
    Publication date: August 23, 2001
    Applicant: Michigan State University, Board of Trustees Operating
    Inventors: Muraleedharan G. Nair, Leslie D. Bourquin, Navindra P. Seeram, Soo-Young Kang
  • Publication number: 20010002407
    Abstract: A method for inhibiting cyclooxygenase enzymes and inflammation in a mammal using a cherry or cherry anthocyanins, bioflavonoids and phenolics is described. In particular a mixture including the anthocyanins, the bioflavonoids and the phenolics is described for this use.
    Type: Application
    Filed: January 16, 2001
    Publication date: May 31, 2001
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Haibo Wang, Gale M. Strasburg, Alden M. Booren, James I. Gray
  • Patent number: 6194469
    Abstract: A method for inhibiting cyclooxygenase enzymes and inflammation in a mammal using a cherry or cherry anthocyanins, bioflavonoids and phenolics is described. In particular a mixture including the anthocyanins, the bioflavonoids and the phenolics is described for this use.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: February 27, 2001
    Assignee: Board of Trustees operating Michigan State Univeristy
    Inventors: Muraleedharan G. Nair, Haibo Wang, Gale M. Strasburg, Alden M. Booren, James I. Gray
  • Patent number: 6150408
    Abstract: Compounds that are isolatable from cherries and have antioxidant activity, and methods for isolating these compounds are described. In particular, the invention relates to 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol and 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,5-diol, which have antioxidant activity. These antioxidant compounds and compositions containing these compounds are useful as food preservatives, dietary supplements, nutraceuticals, and phytoceuticals.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: November 21, 2000
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Haibo Wang, Gale M. Strasburg, Alden M. Booren, James I. Gray
  • Patent number: 5993881
    Abstract: Anthocyanin containing fractions isolated from tart cherries and exhibiting inhibition of oxidation when introduced into various materials is described. The fractions are particularly useful in high and low moisture foods.
    Type: Grant
    Filed: April 16, 1998
    Date of Patent: November 30, 1999
    Assignee: Board of Trustees operating Michigan State University
    Inventors: James Ian Gray, Alden M. Booren, Muraleedharan G. Nair, Yu-Chen Chang, Gale M. Strasburg, Haibo Wang, Enayat A. Gomaa
  • Patent number: 5985636
    Abstract: Anthocyanin containing fractions isolated from tart cherries and exhibiting inhibition of oxidation when introduced into various materials is described. The fractions are particularly useful in high and low moisture foods.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: November 16, 1999
    Assignee: Board of Trustees operating Michigan State University
    Inventors: James Ian Gray, Alden M. Booren, Muraleedharan G. Nair, Gale M. Strasburg, Haibo Wang, Enayat A. Gomaa, Yu-Chen Chang
  • Patent number: 5981775
    Abstract: A process for the preparation of an isoflavone from a 2'-hydroxydeoxybenzoin(I) is described. The process uses prepared N,N'-dimethyl(chloromethylene) ammonium chloride as a reactant with (I) in borontrifluoride etherate or other Lewis acid as a solvent. The isoflavones are known biologically active compounds.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: November 9, 1999
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Balasubramanian Sreenivasan, Muraleedharan G. Nair
  • Patent number: 5691275
    Abstract: Compositions of an alkali metal formononetinate, particularly potassium and sodium, for stimulating the growth of mycorrhizal fungi which colonize the plant and in turn stimulate growth of the plant. The results are improved over formononetin.
    Type: Grant
    Filed: January 29, 1996
    Date of Patent: November 25, 1997
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Gene R. Safir, Robert E. Schutzki, Brendan A. Niemira
  • Patent number: 5665351
    Abstract: A method for controlling fungal diseases in turfgrasses using a Pseudomonas aureofaciens. The Pseudomonas aureofaciens is particularly useful in inhibiting dollar spot (Sclerotinia homoeocarpa) in turfgrasses. The method is environmentally safe and economical.
    Type: Grant
    Filed: September 25, 1996
    Date of Patent: September 9, 1997
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Joseph M. Vargas, Jon F. Powell, Amitabh Chandra, Alvin Ronald Detweiler
  • Patent number: 5658794
    Abstract: A method for controlling fungal diseases in turfgrasses using a Pseudomonas aureofaciens. The Pseudomonas aureofaciens is particularly useful in inhibiting dollar spot (Sclerotinia homoeocarpa) in turfgrasses. The method is environmentally safe and economical.
    Type: Grant
    Filed: December 7, 1995
    Date of Patent: August 19, 1997
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Joseph M. Vargas, Jon F. Powell, Amitabh Chandra, Alvin Ronald Detweiler
  • Patent number: 5478736
    Abstract: A process for the separation of taxanes, particularly taxol, cephalomannine, baccatin III and deacetylbaccatin III, from ornamental yew tissue is described. The process involves a specific solvent mixture of water and 50 to 95 percent by volume methanol, ethanol or acetone and treatment of the resulting extract using activated carbon, preferably charcoal. The taxanes are preferably separated from the crude extract by a normal phase chromatographic step which preferably is through vacuum and then medium pressure column chromatographic separation, using inexpensive silica gel as an absorbent. The silica gel is regenerated by heating in a furnace above about 500.degree. C. to remove adsorbed organic materials.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: December 26, 1995
    Assignee: Board of Trustees operating Michigan State University
    Inventor: Muraleedharan G. Nair
  • Patent number: 5360918
    Abstract: A method for controlling insects using nitrophenyl pyrones is described. The pyrones are preferably derived from Streptomyces sp. by a method involving growth and extraction of the pyrones. A novel pyrone, griseulin is also described.
    Type: Grant
    Filed: November 22, 1993
    Date of Patent: November 1, 1994
    Assignee: Board of Trustees operating Michigan State University
    Inventor: Muraleedharan G. Nair
  • Patent number: 5310754
    Abstract: A method for controlling insects using nitrophenyl pyrones is described. The pyrones are preferably derived from Streptomyces sp. by a method involving growth and extraction of the pyrones. A novel pyrone, griseulin is also described.
    Type: Grant
    Filed: January 15, 1993
    Date of Patent: May 10, 1994
    Assignee: Board of Trustees operating Michigan State University
    Inventor: Muraleedharan G. Nair
  • Patent number: 5279949
    Abstract: A process for the separation of taxanes, particularly taxol, from ornamental yew tissue is described. The process involves a specific solvent mixture of ethanol and water which is between 50 to 80 percent by volume ethanol and decolorizing of the resulting extract using activated carbon containing the crude taxanes. The taxanes are separated from the crude extract by a normal phase chromatographic step which preferably is through vacuum or medium pressure column chromatographic separation, using inexpensive silica gel as an absorbent.
    Type: Grant
    Filed: December 7, 1992
    Date of Patent: January 18, 1994
    Assignee: Board of Trustees operating Michigan State University
    Inventor: Muraleedharan G. Nair