Patents by Inventor Nader Najafi
Nader Najafi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090143696Abstract: An anchor for an implantable sensing device, a sensor unit formed by the anchor and sensing device, and a surgical procedure for implanting the sensor unit for monitoring a physiological parameter within a cavity of a living body, such as an intracranial physiological property. The anchor includes a shank portion and a head portion. The shank portion defines a distal end of the anchor and has a bore defining an opening at the distal end. The head portion defines a proximal end of the anchor and has a larger cross-sectional dimension than the shank portion. The sensor unit comprises the anchor and the sensing device placed and secured within the bore of the anchor so that a sensing element of the sensing device is exposed for sensing the physiological parameter within the cavity.Type: ApplicationFiled: December 1, 2008Publication date: June 4, 2009Applicant: Integrated Sensing Systems, Inc.Inventors: Nader Najafi, Catherine Hook-Morgan, David Joseph Goetzinger, Sonbol Massoud-Ansari
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Publication number: 20090118779Abstract: A modular platform for wireless implantable devices. The platform enables different functional units which either measure or affect a parameter of the patient's body to be interchanged. The modularity of the platform also enables the functional unit to be remote from the remainder of the implantable device. Finally, the modularity of the platform enables different types of power sources to supply power to the wireless implantable device.Type: ApplicationFiled: November 6, 2008Publication date: May 7, 2009Inventors: Nader Najafi, Sonbol Massoud-Ansari
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Publication number: 20090105557Abstract: A system for monitoring a charge-based physiological parameter within an internal organ of a living body, and a sensor adapted to be implanted in the living body and an organ therein. The sensor includes sensing elements adapted to sense the charge-based physiological parameter within the organ, and the sensing elements include at least first and second sensing elements that are electrically conductive, aligned, spaced apart and exposed at the exterior of the sensor. The sensor further includes a device for passing an alternating current from the first to the second sensing elements through an ionic solution contacting the sensing elements. The sensor also includes a device for generating a signal corresponding to the impedance of the ionic solution based on the alternating current.Type: ApplicationFiled: October 17, 2008Publication date: April 23, 2009Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Nader Najafi, Douglas Ray Sparks
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Publication number: 20090105784Abstract: An implantable system and method for deep brain stimulation (DBS) treatments. The implantable system is sufficiently small and self-contained to enable implantation of the entire system within the brain, or optionally within the brain and the surrounding tissue. The system comprises an implantable inductor on which a voltage is induced when subjected to an electromagnetic field, and an implantable device comprising a housing, stimulating elements at an exterior surface of the housing, and electronics within the housing and electrically connected to the implantable inductor. The electronics produces a brain-stimulating current from the voltage induced on the implantable inductor and then delivers the brain-stimulating current to the stimulating elements. Deep brain stimulation is performed by subjecting the inductor to an electromagnetic field to induce a voltage on the inductor that powers the electronics to produce and deliver the brain-stimulating current to the stimulating elements.Type: ApplicationFiled: October 20, 2008Publication date: April 23, 2009Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Sonbol Massoud-Ansari, Nader Najafi
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Publication number: 20090075129Abstract: A microfluidic device and sensing method that utilize a resonating tube configured to have sufficient sensitivity to be capable of sensing the volume of a gas present as bubbles in a liquid or the flow rate and/or density of a gas or gas mixture flowing through the tube. The tube has a freestanding tube portion supported above a surface of a substrate so as to be capable of vibrating in a plane normal to the surface of the substrate. As a gas-containing fluid flows through an internal passage of the tube, a drive signal vibrates the freestanding tube portion at a resonant frequency thereof. Coriolis-induced deflections of the freestanding tube portion are sensed relative to the substrate to produce an output corresponding to the sensed deflections, and the drive signal and/or the output are assessed to determine the volume, density and/or flow rate of the gas of the gas-containing fluid.Type: ApplicationFiled: November 7, 2008Publication date: March 19, 2009Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Douglas Ray Sparks, Richard Thayre Smith, Nader Najafi
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Patent number: 7483805Abstract: A sensing and analysis system, method, and network that make use of a very portable and compact sensor unit and a physically separate electronic unit that serves to power and control the sensor unit, process and optionally display the output of the sensor unit, and transmit the sensor output to other locations, such as over a network. The sensor unit includes a housing, a sensing element within the housing and responsive to an input, and electronic circuitry within the housing and in communication with the sensing element to produce an electrical output based on an output signal generated by the sensing element. A communication providing device delivers instructions generated by the electronic unit to the sensor unit and delivers the electrical output from the sensor unit to the electronic unit.Type: GrantFiled: March 20, 2007Date of Patent: January 27, 2009Assignee: Integrated Sensing Systems, Inc.Inventors: Douglas Ray Sparks, Vincent Cruz, Nader Najafi
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Publication number: 20090005656Abstract: A minimally-invasive surgical procedure for monitoring a physiological parameter within an internal organ of a living body. The procedure entails making a first incision in the body to enable access to the organ. An endoscopic instrument is then inserted through the first incision and a second incision is made therewith through an external wall of the organ and into the internal cavity thereof. A sensing unit is placed in the second incision such that the second incision is occluded by the unit and a proximal end of the unit is outside the organ. The unit includes a sensing device having a sensing element adapted to sense the physiological parameter within the organ, and an anchor to which the sensing device is secured. The first incision is closed, after which a readout device outside the body telemetrically communicates with the sensing device to obtain a reading of the physiological parameter.Type: ApplicationFiled: June 25, 2008Publication date: January 1, 2009Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Nader Najafi, Catherine Hook Morgan
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Publication number: 20080314161Abstract: A microfluidic device for assessing properties of a fluid. The device utilizes a microtube capable of different vibration modes for promoting certain performance and/or structural aspects of the device. The microtube is supported by a base so as to be spaced apart from a substrate surface. The microtube has a peripheral portion surrounding the base, arms supporting the peripheral portion from the base, and a continuous internal microchannel having at least first and second microchannel portions. Each microchannel portion defines a separate flow route, and each flow route originates at the base, continues through a portion of the peripheral portion, and returns to the base. The first and second microchannel portions are fluidically connected to inlet and outlet ports, respectively, within the base. Vibration of the microtube is induced and sensed by driving and sensing elements. Fluid properties are determined from outputs of the sensing elements.Type: ApplicationFiled: June 23, 2008Publication date: December 25, 2008Applicant: Integrated Sensing Systems, Inc.Inventors: Douglas Ray Sparks, Diane Riley, Nader Najafi
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Publication number: 20080269573Abstract: A system and surgical procedure for monitoring physiological parameters within an internal organ of a living body. The procedure entails making a first incision to expose the organ and a second incision through an external wall of the organ and into an internal cavity. A sensing unit is placed in the second incision such that a proximal end thereof remains outside the organ. The unit includes a sensing device having a sensing element for sensing the physiological parameter within the organ, and an anchor to which the sensing device is secured. The unit occludes the second incision and a distal end of the unit does not extend more than one centimeter into the cavity. The anchor is then secured to the wall of the organ, after which the first incision is closed and a readout device telemetrically communicates with the sensing device to obtain a reading of the physiological parameter.Type: ApplicationFiled: April 29, 2008Publication date: October 30, 2008Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Nader Najafi, Sonbol Massoud-Ansari, Catherine Hook Morgan
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Patent number: 7437912Abstract: A method and device for assessing rheological properties of a fluid, including lubricity and viscosity. The invention utilizes a tube into which the fluid is introduced, and relies on tracking the movement of the fluid through the tube either alone or with one or more particles intentionally introduced into the fluid to assess the rheological properties of the fluid. The method and device generally entail flowing the fluid and the optional suspended particle through a passage within the tube, and assessing a rheological property of the fluid within the tube by tracking the movement of the fluid and/or particle through the portion relative to the flow of the fluid through the portion.Type: GrantFiled: July 19, 2005Date of Patent: October 21, 2008Assignee: Integrated Sensing Systems, Inc.Inventors: Douglas Ray Sparks, Nader Najafi
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Publication number: 20080214978Abstract: A method of treating a bodily fluid withdrawn and then returned to a living body. The method involves withdrawing the bodily fluid from the living body and causing the bodily fluid to flow through a treatment system, altering at least the density of the bodily fluid through the action of a second fluid as the bodily fluid flows through the treatment system, sensing at least the density and flow rate of the bodily fluid before the density thereof is altered by the second fluid, sensing at least the density and flow rate of the bodily fluid after the density thereof is altered by the second fluid, sensing at least the density and flow rate of the second fluid, controlling the density and/or flow rate of the second fluid based on the sensed densities and flow rates, and returning the bodily fluid to the living body.Type: ApplicationFiled: April 21, 2008Publication date: September 4, 2008Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Douglas Ray Sparks, Nader Najafi
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Publication number: 20080154535Abstract: A sensing and analysis system, method, and network that make use of a very portable and compact sensor unit and a physically separate electronic unit that serves to power and control the sensor unit, process and optionally display the output of the sensor unit, and transmit the sensor output to other locations, such as over a network. The sensor unit includes a housing, a sensing element within the housing and responsive to an input, and electronic circuitry within the housing and in communication with the sensing element to produce an electrical output based on an output signal generated by the sensing element. A communication providing device delivers instructions generated by the electronic unit to the sensor unit and delivers the electrical output from the sensor unit to the electronic unit.Type: ApplicationFiled: March 20, 2007Publication date: June 26, 2008Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Douglas Ray Sparks, Vincent Cruz, Nader Najafi
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Publication number: 20080152676Abstract: A device capable of delivering precise amounts of one or more antidotes to treat a victim exposed to biological and chemical agents (biochem agents), and also preferably sensing the presence of biochem agents. The delivery device includes a plurality of reservoirs containing antidotes, a manifold to which the reservoirs are fluidically and removably coupled, an outlet on the manifold, a device for selectively releasing at least one of the antidotes from the reservoirs into the manifold, a device for sensing flow of the at least one released antidote, and a device for stopping flow of the at least one released antidote in response to specified amounts of the at least one released antidote having passed through the flow sensing device.Type: ApplicationFiled: February 15, 2008Publication date: June 26, 2008Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Douglas Ray Sparks, Nader Najafi
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Patent number: 7381628Abstract: A process for producing a tube suitable for microfluidic devices. The process uses first and second wafers, each having a substantially uniform doping level. The first wafer has a first portion into which a channel is etched partially therethrough between second and third portions of the first wafer. The first wafer is then bonded to the second wafer so that a first portion of the second wafer overlies the first portion of the first wafer and encloses the channel to define a passage. The second wafer is then thinned so that the first portion thereof defines a thinned wall of the passage. Second and third portions of the second wafer and part of the second and third portions of the first wafer are then removed, and the thinned wall defined by the second wafer is bonded to a substrate such that the passage projects over a recess in the substrate surface. The second and third portions of the first wafer are then removed to define a tube with a freestanding portion.Type: GrantFiled: February 20, 2006Date of Patent: June 3, 2008Assignee: Integrated Sensing Systems, Inc.Inventors: Douglas Ray Sparks, Nader Najafi
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Patent number: 7354429Abstract: A device and method capable of sensing the presence of biochem agents, and preferably also capable of delivering precise amounts of one or more antidotes to treat a victim exposed to the agents. The device includes a freestanding tube portion having an internal passage containing a substance selective to a chemical or biological agent so that matter accumulates within the freestanding tube portion when a fluid drawn through the tube portion contains the agent. When vibrated at resonance, the resonant frequency of the tube portion is indicative of the accumulation of matter and thereby the presence of the agent to which the substance is selective. The device then preferably delivers precise amounts of one or more appropriate antidotes to treat the victim. The device is a sufficiently small and lightweight unit to permit being carried by an individual.Type: GrantFiled: May 27, 2004Date of Patent: April 8, 2008Assignee: Integrated Sensing Systems, Inc.Inventors: Douglas Ray Sparks, Nader Najafi
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Patent number: 7351603Abstract: A process for producing a tube suitable for microfluidic devices. The process uses a uniformly-doped first material having a first portion into which a channel is etched partially through the first material between second and third portions of the first material. The first material is then bonded to a second material so that a first portion of the second material overlies the first portion of the first material and encloses the channel to define a passage. The second and third portions of the second material and part of the second and third portions of the first material are then removed, and the first portion of the second material is bonded to a substrate such that the passage projects over a recess in the substrate surface. The second and third portions of the first material are then removed to define a tube with a freestanding portion.Type: GrantFiled: August 22, 2005Date of Patent: April 1, 2008Assignee: Integrated Sensing Systems, Inc.Inventors: Douglas Ray Sparks, Nader Najafi
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Publication number: 20080077016Abstract: A system for monitoring physical properties of structures within animate and inanimate objects, including internal organs and bones of humans. The system includes sensing and readout devices. The sensing device is adapted to be implanted in a body and attached to a structure within the body, and includes an electrical circuit containing a first inductor coil formed at least in part by a conductor with portions thereof separated by gaps. The first inductor coil is adapted to be physically coupled to the structure so that changes in shape and size of the structure cause changes in shape and/or size of the first inductor coil and/or changes in the gaps, which alter the inductance of the first inductor coil when current flows through the electrical circuit. The readout device is not adapted to be implanted in the patient, and includes an inductor coil capable of electromagnetic telecommunication and/or electromagnetic powering of the sensing device.Type: ApplicationFiled: September 24, 2007Publication date: March 27, 2008Applicant: INTEGRATED SENSING SYSTEMS, INC.Inventors: Douglas Sparks, Nader Najafi
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Publication number: 20080065050Abstract: A device and method capable of sensing the presence of biochem agents, and preferably also capable of delivering precise amounts of one or more antidotes to treat a victim exposed to the agents. The device includes a freestanding tube portion having an internal passage containing a substance selective to a chemical or biological agent so that matter accumulates within the freestanding tube portion when a fluid drawn through the tube portion contains the agent. When vibrated at resonance, the resonant frequency of the tube portion is indicative of the accumulation of matter and thereby the presence of the agent to which the substance is selective. The device then preferably delivers precise amounts of one or more appropriate antidotes to treat the victim. The device is a sufficiently small and lightweight unit to permit being carried by an individual.Type: ApplicationFiled: May 27, 2004Publication date: March 13, 2008Applicant: INTEGRATED SENSING SYSTEMSInventors: Douglas Ray Sparks, Nader Najafi
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Publication number: 20080051863Abstract: An anchor and procedure for placing a medical implant, such as for monitoring physiological parameters. The anchor includes a central body in which a medical implant can be received. Arms and members extend radially from first and second ends, respectively, of the central body. Each member defines a leg extending toward distal portions of the arms to provide a clamping action. The anchor and its implant are placed by coupling first and second guidewires to first and second portions of the anchor, placing an end of a delivery catheter in a wall where implantation is desired, inserting the anchor in the catheter with the guidewires to locate the anchor within the wall, deploying the arms of the anchor at one side of the wall followed by deployment of the members at the opposite side of the wall, and thereafter decoupling the guidewires from the anchor.Type: ApplicationFiled: November 1, 2007Publication date: February 28, 2008Applicant: Integrated Sensing Systems, Inc.Inventors: Richard Schneider, Nader Najafi, David Goetzinger
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Patent number: 7317951Abstract: An anchor and procedure for placing a medical implant, such as for monitoring physiological parameters. The anchor includes a central body in which a medical implant can be received. Arms and members extend radially from first and second ends, respectively, of the central body. Each member defines a leg extending toward distal portions of the arms to provide a clamping action. The anchor and its implant are placed by coupling first and second guidewires to first and second portions of the anchor, placing an end of a delivery catheter in a wall where implantation is desired, inserting the anchor in the catheter with the guidewires to locate the anchor within the wall, deploying the arms of the anchor at one side of the wall followed by deployment of the members at the opposite side of the wall, and thereafter decoupling the guidewires from the anchor.Type: GrantFiled: July 24, 2004Date of Patent: January 8, 2008Assignee: Integrated Sensing Systems, Inc.Inventors: Richard Lee Schneider, Nader Najafi, David J. Goetzinger