Abstract: The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.

Abstract: A telecommunications system (14) includes a chassis (12) defining a front (18), a rear (16), and a plurality of first signal connection locations (38) adjacent the rear (16). A plurality of removable cassettes (10) are housed within the chassis (12), each including a cassette body (68) defining a fixed portion (80) that is coupled to one of the first signal connection locations (38) on the chassis (12) and a movable portion (82) that telescopically slides relative to the fixed portion (80), wherein the movable portion (82) is configured for movement in a direction from the front (18) to the rear (16) of the chassis (12), each cassette (10) defining a plurality of second signal connection locations (58).

Abstract: The invention herein disclosed is related to epitopes useful in methods of diagnosing, treating, and preventing coeliac disease. Therapeutic compositions which comprise at least one epitope are provided.

Abstract: The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.

Abstract: The invention herein disclosed is related to epitopes useful in methods of diagnosing, treating, and preventing coeliac disease. Therapeutic compositions which comprise at least one epitope are provided.

Abstract: The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.

Abstract: Disclosed is a security and alarm system. When sensors detect something of note, they alert a master unit which in turn captures pertinent information (e.g., an image or sound) and places a mobile-telephone call to deliver the alert and the captured information. The recipient of the call (for example, an owner of the system or a security service) evaluates the information and takes appropriate action such as alerting a local police department. Some embodiments offer two-way service: In addition to delivering alerts, the system responds to calls from an authorized user requesting current information. Two-way communications allow some embodiments to deliver “Breach of Peace” alerts to users. In one scenario, a public security service sends out a warning within a geographical area that the peace has been breached. The system receives the warning and alerts its user to the situation. The user then takes appropriate action.

Abstract: A telecommunications system (14) includes a chassis (12) defining a front (18), a rear (16), and a plurality of first signal connection locations (38) adjacent the rear (16). A plurality of removable cassettes (10) are housed within the chassis (12), each including a cassette body (68) defining a fixed portion (80) that is coupled to one of the first signal connection locations (38) on the chassis (12) and a movable portion (82) that telescopically slides relative to the fixed portion (80), wherein the movable portion (82) is configured for movement in a direction from the front (18) to the rear (16) of the chassis (12), each cassette (10) defining a plurality of second signal connection locations (58).

Abstract: A method of diagnosing coeliac disease, or susceptibility to coeliac disease, in an individual comprising: (a) contacting a sample from the host with an agent selected from (i) the epitope comprising sequence which is: SEQ ID NO:1 or 2, or an equivalent sequence from a naturally occurring homologue of the gliadin represented by SEQ ID NO:3, (ii) an epitope comprising sequence comprising: SEQ ID NO:1, or an equivalent sequence from a naturally occurring homologue of the gliadin represented by SEQ ID NO:3, which epitope is an isolated oligopeptide derived from a gliadin protein, (iii) an analogue of (i) or (ii) which is capable of being recognised by a T cell receptor that recognises (i) or (ii), which in the case of a peptide analogue is not more than 50 amino acids in length, or (iv) a product comprising two or more agents as defined in (i), (ii) or (iii), and (b) determining in vitro whether T cells in the sample recognise the agent; recognition by the T cells indicating that the individual has, or is susce

Abstract: A shear blade 10 for a downhole apparatus 50 comprises a body portion 12 and a first cutting edge 21 provided at a cutting end of the shear blade 10, the first cutting edge 21 comprising a sharp edge 22 located at or near a central region of the first cutting edge 21 and at least one blunt edge 23 located at or near at least one outer portion of the first cutting edge 21. In an embodiment, the shear blade 10 has a recess or slot 40 which is provided at or near a central region of a shear face 30 and which extends partially between a first side 27 and a second side 28 and which is generally aligned with the sharp edge 22 of the first cutting edge 21 in a plane substantially parallel to an axis of the throughbore and perpendicular to the first cutting edge 21.

Abstract: A method includes displaying a left panel and a central panel, where the left panel is contiguous to the central panel and oriented on a left side of the central panel. A first selection on the left panel is detected. Content is displayed on the central panel responsive to the first selection. A second selection from the content on the central panel is detected. The central panel is displayed together with a right panel responsive to the second selection. The right panel is contiguous with the central panel and oriented on a right side of the central panel. The left panel is removed in response to the second selection. A third selection on the right panel is detected. The left panel displays choices. The central panel includes different content associated with one of the choices. The right panel includes functions for operation on selected content.

Abstract: A braking system and method for an apparatus or vehicle moved along a pathway by a drive mechanism, for halting the movement of the apparatus or vehicle in the event that the drive mechanism loses power or malfunctions. A conveyance system is provided including a structure defining a pathway, an moving apparatus supported for movement along the pathway, a drive mechanism operatively connected for moving the apparatus along the pathway, a brake rail having along one edge a multiplicity of regularly spaced teeth that define gaps between successive teeth, disposed along the pathway and secured to the structure, and a brake device mounted securely to the apparatus.

Abstract: In one aspect, a method includes etching a magnetic field sensor element covered by a bilayer hardmask. In another aspect, a method includes depositing a silicon nitride on a magnetic field sensor element, depositing a silicon dioxide on the silicon nitride, forming the bilayer mask by etching the silicon dioxide and etching the magnetic field sensor element partially covered by the bilayer hardmask. The magnetic field sensor element includes one of a giant magnetoresistance (GMR) element, a tunneling magnetoresistance (TMR) element or a magnetic tunnel junction (MTJ). The bilayer mask includes the silicon dioxide and the silicon nitride. In a further aspect, a sensor includes a magnetic field sensor element that includes one of a GMR element, a TMR element or a MTJ. The sensor also includes a bilayer hardmask disposed on the magnetic field sensor element. The bilayer mask includes a silicon dioxide and a silicon nitride.

Abstract: An oral cleaning system for communicating a status of a handheld oral cleaning device (10) to a docking station (100). The handheld oral cleaning device includes a controller (70) configured to generate a unique charging cycle for each of a plurality of different charging states. The docking station (100) is configured to receive the handheld oral cleaning device, and includes a secondary charging induction coil configured to detect the unique charging cycle for each of the plurality of different charging periods. The docking station further includes a visual indicator (120) configured to indicate, based on the detected charging cycle, one of the plurality of different charging states of the handheld oral cleaning device.

Abstract: A method of characterizing a storage area network (SAN) includes collecting information associated with the SAN, analyzing the collected information, generating an assessment of one or more aspects of the SAN based on the analyzing, and reporting the assessment. The information collected may include one or more of host information, storage information and network information. The analyzing may further include evaluating information from two or more subsystems that constitute the SAN, and the assessment may be based on technical knowledge associated with the two or more subsystems.

Abstract: A method of managing data of an electronic device includes capturing contents from user interfaces of programs displayed on a display of the electronic device. An application layer is displayed on the display when each content is captured. Each content is moved to the application layer in response to a predetermined input. Contents in the application layer are arranged in a first layout, and can be arranged in a second layout when the second layout is selected.

Abstract: Provided herein are neuroprotective molecules containing a sequence of 25-35 contiguous nucleotides that is at least 80% identical to a contiguous sequence between nucleotide 1 and nucleotide 50 of a mature human tRNA and at least four contiguous guanosine-containing nucleotides, where the sequence of 25-35 contiguous nucleotides contains a D-loop stem structure, the at least four contiguous guanosine-containing nucleotides are located at the 5? end of the neuroprotective molecule, and the neuroprotective molecule contains at least one deoxyribonucleotide.

Abstract: A method of selectively increasing the sensitivity of an insensitive munition by inducing porosity or Joule heating in munitions assembly comprising a power source, an explosive apparatus and a fuze apparatus wherein the explosive apparatus contains a sensitized main explosive composition comprising a secondary explosive and a sensitizing agent. As a result, the otherwise insensitive munition is rendered sensitive to a propagating wave shock by approximately 10 to 25%. To this end, a voltage is applied across the main conductive explosive composition within the insensitive munition. Voltages above certain thresholds cause the decomposition of the explosive material or conductive binder, which leads to an increase in porosity, and therefore the shock sensitivity.

Abstract: The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.

Abstract: A communications connection system includes a fiber optic connector including a storage device having memory configured to store physical layer information. The storage device also includes at least one contact member that is electrically connected to the memory. Certain types of fiber optic connectors have the storage device mounted to a key of the fiber optic connector. Certain types of fiber optic connectors have the storage device mounted in a cavity defined in the fiber optic connector.