Abstract: Provided herein are neuroprotective molecules containing a sequence of 25-35 contiguous nucleotides that is at least 80% identical to a contiguous sequence between nucleotide 1 and nucleotide 50 of a mature human tRNA and at least four contiguous guanosine-containing nucleotides, where the sequence of 25-35 contiguous nucleotides contains a D-loop stem structure, the at least four contiguous guanosine-containing nucleotides are located at the 5? end of the neuroprotective molecule, and the neuroprotective molecule contains at least one deoxyribonucleotide.

Abstract: Systems and methods for dispensing a product are provided. A plurality of product ingredients are associated with a product dispenser that is operable to form a plurality of selectable products from the plurality of products ingredients. Input for a selected product is received and a recipe that defines the ratio of product ingredients for forming the selected product is identified. The dispense of each of the respective product ingredients is commenced based at least in part on the identified recipe, and the dispense of each of the respective product ingredients is independently monitored during the dispense of the selected product.

Abstract: Provided is a computing-system monitor configured to monitor a plurality of computing-systems each having a plurality of monitored computing-instances. The computing-system monitor may include a plurality of collectors, each collector executed by one of a plurality of monitored computing-instances, wherein the plurality of monitored computing-instances each are part of one of a plurality of separately monitored computing systems, and wherein each of the collectors is operable to output metrics of a corresponding monitored computing-instance executing that collector. The computing-system monitor may also include an analytics platform, the analytics platform having a plurality of analytic computing-instances, the analytics platform being operable to receive metrics output by the plurality of collectors, calculate statistics with the analytic computing-instances based on the received metrics, and output the calculated statistics.

Abstract: Provided is a computing-system monitor configured to monitor a plurality of computing-systems each having a plurality of monitored computing-instances. The computing-system monitor may include a plurality of collectors, each collector executed by one of a plurality of monitored computing-instances, wherein the plurality of monitored computing-instances each are part of one of a plurality of separately monitored computing systems, and wherein each of the collectors is operable to output metrics of a corresponding monitored computing-instance executing that collector. The computing-system monitor may also include an analytics platform, the analytics platform having a plurality of analytic computing-instances, the analytics platform being operable to receive metrics output by the plurality of collectors, calculate statistics with the analytic computing-instances based on the received metrics, and output the calculated statistics.

Abstract: An apparatus for perforating a length of pierceable material which includes a first roller, the length of pierceable material being in engagement with and at least partially circumscribing said first roller; and a second roller disposed in close proximity to the first roller. The second roller, which is provided with a plurality of piercing members, is movable from a first position wherein the piercing members are spaced apart from the first roller to a second position wherein selected ones of the piercing members pierce the length of pierceable material. Uniquely, the first roller has a plurality of transversely spaced grooves that receive the extremities of the piercing members when the first roller is in the second position.

Abstract: A system for distributed authentication includes a client machine, in a first domain in a federation, that receives from a user a first set of authentication credentials. The system also includes an intermediate machine in a second domain in the federation, a server, also in the second domain, a password management program executing on the server and a non-federated resource. The intermediate machine authenticates the user responsive to receiving the first set of authentication credentials and identifies a second set of authentication credentials. The server in the second domain authenticates the user, responsive to the second set of authentication credentials. The password management program, executing on the server, retrieves a third set of authentication credentials associated with the user. The non-federated resource authenticates the user, responsive to receiving, from the password management program, the third set of authentication credentials.

Abstract: A peptide analogue which is not more than 50 amino acids in length, and which is capable of being recognized by a T cell receptor that recognizes an epitope comprising sequence 62PQPELPY68 (SEQ ID NO:1), and fusion proteins, pharmaceutical compositions, and kits comprising the same, are provided herewith. Also provided are methods of diagnosing coeliac disease, or susceptibility to coeliac disease, in an individual comprising contacting a sample from the individual with a peptide analogue and determining in vitro whether T cells in the sample recognize the peptide analogue.

Abstract: Disclosed is a security and alarm system. When sensors detect something of note, they alert a master unit which in turn captures pertinent information (e.g., an image or sound) and sends the alert and the captured information. The recipient of the alert (for example, an owner of the system or a security service) evaluates the information and takes appropriate action such as alerting a local police department. Some embodiments offer two-way service: In addition to delivering alerts, the system responds to alerts from an authorized user requesting current information. Two-way communications allow some embodiments to deliver “Breach of Peace” alerts to users. In one scenario, a public security service sends out a warning within a geographical area that the peace has been breached. The system receives the warning and alerts its user to the situation. The user can then take appropriate action.

Abstract: A system for distributed authentication includes a client machine, in a first domain in a federation, that receives from a user a first set of authentication credentials. The system also includes an intermediate machine in a second domain in the federation, a server, also in the second domain, a password management program executing on the server and a non-federated resource. The intermediate machine authenticates the user responsive to receiving the first set of authentication credentials and identifies a second set of authentication credentials. The server in the second domain authenticates the user, responsive to the second set of authentication credentials. The password management program, executing on the server, retrieves a third set of authentication credentials associated with the user. The non-federated resource authenticates the user, responsive to receiving, from the password management program, the third set of authentication credentials.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to workload management of backend systems and provide a novel and non-obvious method, system and computer program product for limiting a request rate from a client based on a health state of a server system. In one embodiment of the invention, a computer-implemented method for limiting a request rate from a client based on a health state of a server system that includes monitoring a server system, determining a measure of health of the server system, sending the determined measure of health to a client submitting a request to the server system and receiving a subsequent request from the client that is delayed by a time period, wherein the time period is based at least in part upon the determined measure of health.

Abstract: Among other things, a case forming system is provided. The system includes a conveyance apparatus for conveying case precursors along a conveyance path and a case set-up apparatus characterized by a case forming member. Upstream case precursors are conveyed along the conveyance path for operation thereupon by the case forming member. A case forming mandrel of a mandrel assembly is movably mounted in relation to the conveyance apparatus for continuos motion with respect thereto. The continuous motion is delimited by travel of the case forming mandrel between an upstream locus and a downstream locus of the conveyance path, and reversible extension of the case forming mandrel towards case precursors during travel between the upstream locus and the downstream locus of the conveyance path.

Abstract: The invention is directed to RNA molecules that can be used to inhibit protein synthesis and to induce cells to undergo apoptosis. It also includes pharmaceutical compositions containing the RNAs that can be used in treating or preventing tumors; abnormal dermatological growths and viral infections.

Abstract: Techniques are disclosed for calculating large precision common logarithms. A common logarithm may be calculated using addition and/or subtraction of known logarithm values. Embodiments of the invention permit calculation of common logarithms of real numbers stored within character arrays, where each element of the array corresponds to a digit in the real number.

Abstract: A refrigerator includes a refrigerator cabinet, a refrigerator compartment disposed within the refrigerator cabinet, a freezer compartment disposed within the refrigerator cabinet, and a battery. There is at least one fan disposed within the refrigerator cabinet and electrically connected to the battery. The battery powers the at least one fan during a power outage to thereby circulate air from the freezer compartment to the refrigerator compartment. The at least one fan may be a direct current operated fan. The refrigerator may also include an inverter and the at least one fan may then be an alternating current operated fan electrically connected to the inverter. The battery may be disposed within the refrigerator cabinet or may be external to the refrigerator cabinet.

Abstract: The present invention provides a method and system of storing information for drawing an object on a computer system that includes providing a palette file that includes a set of first labels matched with numerical values, tagging a vector graphics file for drawing the object with second labels, translating the second labels into one or more of the first labels, and plugging in values stored in the palette file associated with the translated second labels into the tagged vector graphics file.

Abstract: A magnetic element and a method for making a magnetic element. The method includes patterning a first electrode material to form a first electrode on a substrate and depositing filler material on the substrate around the first electrode. The method further includes polishing to form a planar surface of filler and the first electrode. A magnetic cell is formed on the planar surface and a second electrode is formed on the magnetic cell. In some embodiments, the first electrode has an area that is at least 2:1 to the area of the magnetic cell.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to workload management of backend systems and provide a novel and non-obvious method, system and computer program product for limiting a request rate from a client based on a health state of a server system. In one embodiment of the invention, a computer-implemented method for limiting a request rate from a client based on a health state of a server system that includes monitoring a server system, determining a measure of health of the server system, sending the determined measure of health to a client submitting a request to the server system and receiving a subsequent request from the client that is delayed by a time period, wherein the time period is based at least in part upon the determined measure of health.

Abstract: A remote and receiver system that allows user control over current output to a direct current motor. The control of current output grants users the ability to control the speed of rotation of a direct current motor. A speed controlled direct current motor can be utilized to control motor speeds within system such as a salt spreader. This can give users control over the flow rate and the spreading area of the salt.

Abstract: The invention is directed to RNA molecules that can be used to inhibit protein synthesis and to induce cells to undergo apoptosis. It also includes pharmaceutical compositions containing the RNAs that can be used in treating or preventing tumors; abnormal dermatological growths and viral infections.

Abstract: Apparatus and method for quickly disconnecting a wetted parts subassembly from a paint spray gun wherein the wetted parts subassembly includes a spray tip, pump cylinder and piston and paint cup components including a pump housing cylinder support carrying the pump cylinder and having a pair of protrusions formed on a pump housing cylinder support, a frame having a pair of slots aligned to receive the protrusions when the pump housing cylinder support is received in the frame, a locking lever pivotably attached to the frame adjacent at least one of the slots and movable between a latched position wherein the pump housing cylinder support is retained to the frame, and an unlatched position wherein the pump housing cylinder support is removable from the frame. A passive retention feature frictionally engages the wetted parts subassembly with the frame when the wetted parts subassembly is received in the frame.