Abstract: A multi-signal fluorescent probe, represented by: A method for preparing the multi-signal fluorescent probe includes: (a) adding 2-methoxyphenothiazine and ethyl iodide into a mixture of dichloromethane (DCM) and acetonitrile followed by a first reaction and a first post-treatment to obtain 10-ethyl-2-methoxy-10H-phenothiazine; (b) adding boron tribromide into the 10-ethyl-2-methoxy-10H-phenothiazine under an inert gas followed by a second reaction under an ice bath and a second post-treatment to obtain 10-ethyl-10H-phenothiazin-2-ol; and (c) mixing the 10-ethyl-10H-phenothiazin-2-ol, malonic acid, zinc chloride and phosphorus oxychloride followed by a third reaction and a third post-treatment to obtain the multi-signal fluorescent probe. A use of the multi-signal fluorescent probe in the detection of intracellular ONOO? and Na2S2 is also provided.

Abstract: A testing device includes an elongated member and a tube assembly. The tube assembly has a first end and a second end. The tube assembly is configured to receive the elongated member at the second end. The tube assembly includes a plurality of chambers, including a first chamber and a second chamber. The first chamber and the second chamber are separated by a membrane. The tube assembly further includes a spring positioned at the second end of the tube assembly. The tube assembly further includes a spring retainer configured to prevent the spring from decompressing when in a locked position and permit the spring to decompress when in an unlocked position.

Abstract: A quantization parameter signalling mechanism for both SDR and HDR content in video coding is described using two approaches. The first approach is to send the user-defined QpC table directly in high level syntax. This leads to more flexible and efficient QP control for future codec development and video content coding. The second approach is to signal luma and chroma QPs independently. This approach eliminates the need for QpC tables and removes the dependency of chroma quantization parameter on luma QP.

Abstract: There are provided methods and apparatus for video usability information (VUI) for scalable video coding (SVC). An apparatus includes an encoder (100) for encoding video signal data into a bitstream. The encoder specifies video user information, excluding hypothetical reference decoder parameters, in the bitstream using a high level syntax element. The video user information corresponds to a set of interoperability points in the bitstream relating to scalable video coding (340, 355).

Abstract: A device and a method for ultrasonic detecting a mechanical member based on magnetic fluid coupling. The device comprises a magnetic field generating apparatus, magnetic fluid and an ultrasonic probe. The magnetic field generating apparatus has a cylindrical structure, into which the magnetic fluid is injected, where an upper portion of the apparatus is provided with the ultrasonic probe a front end that vertically extends into a liquid level of the magnetic fluid, and a bottom portion of the apparatus covers a detected position of a member under detection. The magnetic fluid at least contains magnetic suspension particles and oil-based or water-based liquid. With the device and the method, the ultrasonic probe is coupled with the member under detection to realize ultrasonic detecting of the service stress of the member under detection.

Abstract: Methods and apparatus are provided for signaling intra prediction for large blocks for video encoders and decoders. An apparatus includes a video encoder (400) for encoding picture data for at least one large block in a picture by signaling intra prediction for the at least one large block. The intra prediction is signaled by selecting a basic coding until size and assigning a single spatial intra partition type for the basic coding until size. The single spatial intra partition type is selectable from among a plurality of spatial intra partition types. The at least one large block has a large block size greater than a block size of the basic coding unit. The intra prediction is hierarchical layer intra prediction and is performed for the at least one large block by at least one of splitting from the large block size to the basic coding until size and merging from the basic coding unit size to the large block size.

Abstract: Provided herein, in some aspects, are methods of imaging molecules without a microscope or other specialized equipment, referred to herein as “microscope-free imaging (MFI).” Herein, “molecular instruments” (e.g., DNA-based and protein-based molecules) are used, instead of microscopes, in a “bottom-up” approach for inspecting molecular targets.

Abstract: A device for reducing and homogenizing residual stress of a metal frame including a substrate, a frame fixing device and ultrasonic vibrators. A groove with an upward opening is provided in the middle of the substrate, and a shape enclosed by vertical side walls of the groove matches a shape of an outer frame of a metal frame to be processed. A plurality of through holes that are horizontally diverged are arranged around the side walls of the groove, and the through holes are vertically intersected with the groove. The ultrasonic vibrators are provided on the substrate and front ends of the ultrasonic vibrators extend into respective through holes to abut against the metal frame in the groove. The frame fixing device is also arranged in the groove where the metal frame is located, after the metal frame to be processed is placed in the groove.

Abstract: Methods and systems for frame rate scalability are described. Support is provided for input and output video sequences with variable frame rate and variable shutter angle across scenes, or for input video sequences with fixed input frame rate and input shutter angle, but allowing a decoder to generate a video output at a different output frame rate and shutter angle than the corresponding input values. Techniques allowing a decoder to decode more computationally-efficiently a specific backward compatible target frame rate and shutter angle among those allowed are also presented.

Abstract: The present disclosure is related to the technical field of propellant performance research, and in particular, to a method for reducing propellant curing residual stress by a high-energy acoustic beam. The method includes the following steps: injecting a propellant slurry into a curing container and waiting for the propellant slurry to start curing; actuating, when the propellant slurry starts curing, a high-energy acoustic beam generator and a high-energy acoustic beam transducer to continuously emit high-energy acoustic beam to the propellant slurry in the curing container until the propellant slurry is cured to form a propellant grain; and closing the high-energy acoustic beam generator and the high-energy acoustic beam transducer. The method for reducing propellant curing residual stress by high-energy acoustic beam provided in the present disclosure can reduce residual stress inside the propellant in an effective manner, thereby ensuring operation safety of the aerospace equipment.

Abstract: In a method to improve backwards compatibility when decoding high-dynamic range images coded in a wide color gamut (WCG) space which may not be compatible with legacy color spaces, hue and/or saturation values of images in an image database are computed for both a legacy color space (say, YCbCr-gamma) and a preferred WCG color space (say, IPT-PQ). Based on a cost function, a reshaped color space is computed so that the distance between the hue values in the legacy color space and rotated hue values in the preferred color space is minimized. HDR images are coded in the reshaped color space. Legacy devices can still decode standard dynamic range images assuming they are coded in the legacy color space, while updated devices can use color reshaping information to decode HDR images in the preferred color space at full dynamic range.

Abstract: In a method to improve the coding efficiency of high-dynamic range (HDR) images, a decoder parses sequence processing set (SPS) data from an input coded bitstream to detect that an HDR extension syntax structure is present in the parsed SPS data. It extracts from the HDR extension syntax structure post-processing information that includes one or more of a color space enabled flag, a color enhancement enabled flag, an adaptive reshaping enabled flag, a dynamic range conversion flag, a color correction enabled flag, or an SDR viewable flag. It decodes the input bitstream to generate a preliminary output decoded signal, and generates a second output signal based on the preliminary output signal and the post-processing information.

Abstract: The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression.

Abstract: The precision of up-sampling operations in a layered coding system is preserved when operating on video data with high bit-depth. In response to bit-depth requirements of the video coding or decoding system, scaling and rounding parameters are determined for a separable up-scaling filter. Input data are first filtered across a first spatial direction using a first rounding parameter to generate first up-sampled data. First intermediate data are generated by scaling the first up-sampled data using a first shift parameter. The intermediate data are then filtered across a second spatial direction using a second rounding parameter to generate second up-sampled data. Second intermediate data are generated by scaling the second up-sampled data using a second shift parameter. Final up-sampled data may be generated by clipping the second intermediate data.

Abstract: Methods and apparatus are provided for determining quantization parameter predictors from a plurality of neighboring quantization parameters. An apparatus includes an encoder for encoding image data for at least a portion of a picture using a quantization parameter predictor for a current quantization parameter to be applied to the image data. The quantization parameter predictor is determined using multiple quantization parameters from previously coded neighboring portions. A difference between the current quantization parameter and the quantization parameter predictor is encoded for signaling to a corresponding decoder.

Abstract: There are provided methods and apparatus for video usability information (VUI) for scalable video coding (SVC). An apparatus includes an encoder (100) for encoding video signal data into a bitstream. The encoder specifies video user information, excluding hypothetical reference decoder parameters, in the bitstream using a high level syntax element. The video user information corresponds to a set of interoperability points in the bitstream relating to scalable video coding (340, 355).

Abstract: In a method to improve backwards compatibility when decoding high-dynamic range images coded in a wide color gamut (WCG) space which may not be compatible with legacy color spaces, hue and/or saturation values of images in an image database are computed for both a legacy color space (say, YCbCr-gamma) and a preferred WCG color space (say, IPT-PQ). Based on a cost function, a reshaped color space is computed so that the distance between the hue values in the legacy color space and rotated hue values in the preferred color space is minimized HDR images are coded in the reshaped color space. Legacy devices can still decode standard dynamic range images assuming they are coded in the legacy color space, while updated devices can use color reshaping information to decode HDR images in the preferred color space at full dynamic range.

Abstract: Provided herein are methods, compositions, kits, and systems for the detection of neutralization targets such as neutralizing antibodies.

Abstract: A method for controlling deformation of a large-scale crankshaft comprising detecting and recording stress value(s) of part(s) to be regulated by the crankshaft; fixing the crankshaft on a tool to couple transmitting ends of high-energy acoustic beam transducers with the part(s) to be regulated; turning on the high-energy acoustic beam transducers to emit high-energy acoustic beams into the crankshaft, controlling working frequencies of the high-energy acoustic beam transducers within a range of 10-30 kHz, and setting a predicted regulation and control time according to the stress value(s) of the part(s) to be regulated; and closing the high-energy acoustic beam transducers when the predicted regulation and control time is reached, and taking the crankshaft out of the tool.

Abstract: The present application relates to the technical field of the research on energetic composite materials, and in particular to a device and a method for controlling transverse and longitudinal stress waves during the curing process of energetic composite materials. The device for controlling transverse and longitudinal stress waves comprises a curing vessel containing an energetic composite materials to be cured; a vertical exciter that is vertically incident to the curing vessel; and a plurality of oblique exciters which are arranged around the vertical exciter and obliquely incident to the curing vessel, wherein the oblique exciters have inclination angles between a first critical angle and a second critical angle. By means of incident transverse and longitudinal waves, the internal radial residual stress and the internal axial residual stress are reduced and homogenized, so as to improve stability and mechanical property of the energetic composite materials during curing.