Abstract: The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression.

Abstract: The precision of up-sampling operations in a layered coding system is preserved when operating on video data with high bit-depth. In response to bit-depth requirements of the video coding or decoding system, scaling and rounding parameters are determined for a separable up-scaling filter. Input data are first filtered across a first spatial direction using a first rounding parameter to generate first up-sampled data. First intermediate data are generated by scaling the first up-sampled data using a first shift parameter. The intermediate data are then filtered across a second spatial direction using a second rounding parameter to generate second up-sampled data. Second intermediate data are generated by scaling the second up-sampled data using a second shift parameter. Final up-sampled data may be generated by clipping the second intermediate data.

Abstract: Methods and apparatus are provided for determining quantization parameter predictors from a plurality of neighboring quantization parameters. An apparatus includes an encoder for encoding image data for at least a portion of a picture using a quantization parameter predictor for a current quantization parameter to be applied to the image data. The quantization parameter predictor is determined using multiple quantization parameters from previously coded neighboring portions. A difference between the current quantization parameter and the quantization parameter predictor is encoded for signaling to a corresponding decoder.

Abstract: There are provided methods and apparatus for video usability information (VUI) for scalable video coding (SVC). An apparatus includes an encoder (100) for encoding video signal data into a bitstream. The encoder specifies video user information, excluding hypothetical reference decoder parameters, in the bitstream using a high level syntax element. The video user information corresponds to a set of interoperability points in the bitstream relating to scalable video coding (340, 355).

Abstract: In a method to improve backwards compatibility when decoding high-dynamic range images coded in a wide color gamut (WCG) space which may not be compatible with legacy color spaces, hue and/or saturation values of images in an image database are computed for both a legacy color space (say, YCbCr-gamma) and a preferred WCG color space (say, IPT-PQ). Based on a cost function, a reshaped color space is computed so that the distance between the hue values in the legacy color space and rotated hue values in the preferred color space is minimized HDR images are coded in the reshaped color space. Legacy devices can still decode standard dynamic range images assuming they are coded in the legacy color space, while updated devices can use color reshaping information to decode HDR images in the preferred color space at full dynamic range.

Abstract: Provided herein are methods, compositions, kits, and systems for the detection of neutralization targets such as neutralizing antibodies.

Abstract: A method for controlling deformation of a large-scale crankshaft comprising detecting and recording stress value(s) of part(s) to be regulated by the crankshaft; fixing the crankshaft on a tool to couple transmitting ends of high-energy acoustic beam transducers with the part(s) to be regulated; turning on the high-energy acoustic beam transducers to emit high-energy acoustic beams into the crankshaft, controlling working frequencies of the high-energy acoustic beam transducers within a range of 10-30 kHz, and setting a predicted regulation and control time according to the stress value(s) of the part(s) to be regulated; and closing the high-energy acoustic beam transducers when the predicted regulation and control time is reached, and taking the crankshaft out of the tool.

Abstract: The present application relates to the technical field of the research on energetic composite materials, and in particular to a device and a method for controlling transverse and longitudinal stress waves during the curing process of energetic composite materials. The device for controlling transverse and longitudinal stress waves comprises a curing vessel containing an energetic composite materials to be cured; a vertical exciter that is vertically incident to the curing vessel; and a plurality of oblique exciters which are arranged around the vertical exciter and obliquely incident to the curing vessel, wherein the oblique exciters have inclination angles between a first critical angle and a second critical angle. By means of incident transverse and longitudinal waves, the internal radial residual stress and the internal axial residual stress are reduced and homogenized, so as to improve stability and mechanical property of the energetic composite materials during curing.

Abstract: Methods and apparatus are provided for improved entropy encoding and decoding. An apparatus includes a video encoder (200) for encoding at least a block in a picture by transforming a residue of the block to obtain transform coefficients, quantizing the transform coefficients to obtain quantized transform coefficients, and entropy coding the quantized transform coefficients. The quantized transform coefficients are encoded using a flag to indicate that a current one of the quantized transform coefficients being processed is a last non-zero coefficient for the block having a value greater than or equal to a specified value.

Abstract: Methods and apparatus are provided for unified significance map coding. An apparatus includes a video encoder (400) for encoding transform coefficients for at least a portion of a picture. The transform coefficients are obtained using a plurality of transforms. One or more context sharing maps are generated for the transform coefficients based on a unified rule. The one or more context sharing maps are for providing at least one context that is shared among at least some of the transform coefficients obtained from at least two different ones of the plurality of transforms.

Abstract: Sample data and metadata related to spatial regions in images may be received from a coded video signal. It is determined whether specific spatial regions in the images correspond to a specific region of luminance levels. In response to determining the specific spatial regions correspond to the specific region of luminance levels, signal processing and video compression operations are performed on sets of samples in the specific spatial regions. The signal processing and video compression operations are at least partially dependent on the specific region of luminance levels.

Abstract: Methods and apparatus are provided for determining quantization parameter predictors from a plurality of neighboring quantization parameters. An apparatus includes an encoder for encoding image data for at least a portion of a picture using a quantization parameter predictor for a current quantization parameter to be applied to the image data. The quantization parameter predictor is determined using multiple quantization parameters from previously coded neighboring portions. A difference between the current quantization parameter and the quantization parameter predictor is encoded for signaling to a corresponding decoder.

Abstract: A device for performing an assay comprises a tube, a cap, an insert, and a reaction container. The tube includes a lateral flow strip disposed therein. The cap is coupled to the tube and includes a hollow interior defined at least partially therethrough. The insert is configured to be at least partially received within the hollow interior of the cap. The reaction container includes a cavity configured to store one or more fluids therein, and is rotatably coupled to the cap such that rotation of the cap relative to the reaction container causes (i) mixing of the one or more fluids and (ii) at least a portion of the mixed fluids to be delivered from the reaction container to the lateral flow strip via the insert.

Abstract: The present disclosure relates to a method for reducing and homogenizing residual stress of a component, which comprises: detecting stress value(s) of regulation portion(s) of the component; placing the component in a container containing a fluid medium so as to immerse the component in the fluid medium; emitting, by an acoustic wave generator, an elastic wave to the fluid medium in a manner of emitting towards the regulation portion(s) of the component, and determining an emitting period of time and a frequency of the elastic wave based on the stress value(s); returning to the step S1 when the emitting period of time has elapsed, until the stress value(s) is stable. The method and the device solve the problems that it is difficult to reduce and homogenize the residual stress on high-precision machined components, complex structural components, thin-walled structural components, and low-stiffness components.

Abstract: A multi-signal fluorescent probe, represented by: A method for preparing the multi-signal fluorescent probe includes: (a) adding 2-methoxyphenothiazine and ethyl iodide into a mixture of dichloromethane (DCM) and acetonitrile followed by a first reaction and a first post-treatment to obtain 10-ethyl-2-methoxy-10H-phenothiazine; (b) adding boron tribromide into the 10-ethyl-2-methoxy-10H-phenothiazine under an inert gas followed by a second reaction under an ice bath and a second post-treatment to obtain 10-ethyl-10H-phenothiazin-2-ol; and (c) mixing the 10-ethyl-10H-phenothiazin-2-ol, malonic acid, zinc chloride and phosphorus oxychloride followed by a third reaction and a third post-treatment to obtain the multi-signal fluorescent probe. A use of the multi-signal fluorescent probe in the detection of intracellular ONOO- and Na2S2 is also provided.

Abstract: The technology described herein is directed to methods, kits, compositions, devices, and systems for detecting a target nucleic acid, such as a viral RNA. In one aspect, described herein are methods of detecting the target nucleic acid. In other aspects, described herein are compositions, kits, devices, and systems suitable to practice the methods described herein to detect the target nucleic acid.

Abstract: Methods, systems, and bitstream syntax are described for constrained processing in video coding. Using one or more syntax elements and either explicit or implicit signaling, an encoder may signal to compliant decoders that certain features of the main profile, such as subpictures and multi-layered scalable coding, are disabled.

Abstract: A method for reducing and homogenizing residual stress of a metal frame based on elastic acoustic waves that includes determining an injection scheme of elastic acoustic waves based on residual stress distribution and material characteristics of a metal frame, where the injection scheme comprises at least one of the number of injection directions and corresponding injection direction(s), an excitation scheme and working parameters of the elastic acoustic waves; placing the metal frame in a substrate and fixing the inner and outer frames of the metal frame; assembling an excitation device for the elastic acoustic waves based on the determined excitation scheme of the elastic acoustic waves; injecting the acoustic waves into the metal frame from at least one direction; and performing the reduction and homogenization for multiple rounds if the reduction and homogenization of the residual stress of the metal frame in a single round does not meet the requirement.

Abstract: An ultrasonic test device and test method for service stress of a moving mechanical component, where the device comprises an ultrasonic probe, a coupling fluid, a pressure-maintaining cover and universal wheels. The cover is vertically arranged above an inspected position of an inspected component, an interior of the pressure-maintaining cover is filled with coupling fluid, a bottom of the cover is provided with a structure permeable to the coupling fluid to form a coupling fluid film between the inspected position and the bottom of the cover, and a top of the cover is equipped with the ultrasonic probe. A detection part at a lower part of the ultrasonic probe extends into the coupling fluid of the cover and is vertical to the bottom of the cover without contact. The distance between the ultrasonic probe and the inspected component is kept unchanged through the universal wheels.

Abstract: A device and a method for ultrasonic detecting a rotating member based on magnetic fluid coupling, wherein the device comprises an ultrasonic probe, magnetic field protection rings, magnetic fluid and a magnetic fluid protection cover. The ultrasonic probe is arranged above the rotating member that is horizontally placed. Front ends of a transmitting ultrasonic transducer and a receiving ultrasonic transducer of the ultrasonic probe are provided with the magnetic field protection rings for generating magnetic fields in the magnetic field protection rings. The protective cover is sleeved on a circumferential outer side of the rotating member where a detected position is located, and the front ends of the ultrasonic probe are arranged to penetrate through the magnetic fluid protective cover. A cavity formed between the magnetic fluid protective cover and the rotating member is filled with the magnetic fluid and the magnetic fluid is a liquid mixture solution.