Abstract: A retention assembly is for a patient interface device. The patient interface device includes a cushion member structured to engage a face of a patient. The retention assembly includes: a retention member structured to be coupled to the cushion member; a headgear member; a first interconnect member removably coupled to the retention member; and a second interconnect member removably coupled to the headgear member. The second interconnect member is removably coupled to the first interconnect member in order to couple the headgear member to the retention member.

Abstract: Provided is a spring drive cam for a spring drive of a circuit breaker including a disc-like shape configured for rotating around a rotation axis in the spring drive, whereby the disc-like shape comprises a radius (R) that changes depending on an angle (?) of the radius (R) relative to a base angle (?0), and whereby a rate (dR/d?) defined by a change of the radius (R) per change of the angle (?) is ?0.3 mm/°.

Abstract: Robotic surgical systems and methods for controlling movement of a tool relative to a tool path. An input is received from a force/torque sensor in response to user forces/torques manually applied to the tool by a user. A component of force is calculated tangential to the path based on the input. An effective feed rate is calculated to advance the tool along the path based on the tangential component. Virtual constraints are defined on movement of the tool along the path with respect to three degrees of freedom and based on the effective feed rate to promote movement of the tool along the path. Dynamics of the tool are virtually simulated based on the virtual constraints and the input from the force/torque sensor. The manipulator is commanded to advance the tool along the path based on the virtual simulation.

Abstract: The present invention relates to compositions comprising a silicate and methods of use thereof. In particular, the compositions of the present invention are suitable for treating inflammatory conditions, cancer, bacterial and viral infections, and infected and uninfected wounds. The compositions of the present invention can also be useful in treating spinal cord injury, tissue remodeling, and promoting bone growth and repair.

Abstract: A cell washer is disclosed. The cell washer includes a vessel configured to hold cells. The vessel includes an elongated body including an opening, an inner surface, and a pocket defined by a first inner surface portion of the inner surface disposed between and radially outward relative to a second inner surface portion and a third inner surface portion of the inner surface, and a cavity. The vessel also includes an actuating device capable of causing the vessel to spin about an axis.

Abstract: Phototropin is a blue light receptor, which mediates a variety of blue-light elicited physiological processes in plants and algae. In higher plants these processes include phototropism, chloroplast movement and stomatal opening. In the green alga Chlamydomonas reinhardtii, phototropin plays a vital role in progression of the sexual life cycle and in the control of the eye spot size and light sensitivity Phototropin is also involved in blue-light mediated changes in the synthesis of chlorophylls, carotenoids, chlorophyll binding proteins. We compared the transcriptome of phototropin knock out (PHOT KO) mutant and wild-type parent to analyze differences in gene expression in high light grown cultures (500 µmol photons m-2s-1). Our results indicate the up-regulation of genes involved in photosynthetic electron transport chain, carbon fixation pathway, starch, lipid, and cell cycle control genes.

Abstract: In some embodiments, a downhole drilling system may include a pulse-generating circuit, a drill bit including a first pair of electrodes electrically coupled to the pulse-generating circuit to receive a first electrical pulse from the pulse-generating circuit and form a first electrical arc between the first pair of electrodes during a pulsed drilling operation. The system further includes a sensor to record responses to the first electrical pulse during the pulsed drilling operation and a sensor analysis system communicatively coupled to the sensor, where the sensor analysis system is configured to obtain a first measurement from the sensor representing the responses recorded by the sensor during the pulsed drilling operation. Additionally, the system may determine a first value of a dielectric constant associated with a portion of a formation in proximity to the drill bit, where the first value of the dielectric constant is based on the first measurement.

Abstract: A continuous inkjet printer (5) having a printhead (7) that includes first and second ink droplet generators (8, 9), each operable to generate a stream (10) of ink droplets, and a common gutter (11) arranged to receive unprinted ink droplets from the first and second ink droplet generators (8, 9), the printer (5) further including control means configured to determine receipt into the common gutter (11) of ink droplets from the first and second ink droplet generators (8, 9), wherein the control means are operable to use a single sensor (17) to determine receipt into the common gutter (11) of ink droplets from one, both, or neither of the first and second ink droplet generators (8, 9).

Abstract: Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch.

Abstract: A personal vaporizer device, especially an electronic smoking article, comprises a cartridge which includes a reservoir for storing a liquid to be vaporized; and an elongate body portion to which the cartridge is connected. The elongate body portion comprises a cover member which is movable in a longitudinal direction of the body portion between a first position and a second position, wherein the cartridge is substantially covered or obscured by the cover member in the first position. In the second position, the cover member is retracted.

Abstract: Techniques for low power gunshot sensor testing are disclosed. An acoustic generator and an infrared generator are disposed in a housing. The housing encompasses the acoustic generator and the infrared generator. The housing covers the gunshot sensor. The acoustic generator and the infrared generator are used for testing a gunshot sensor. The infrared generator and the acoustic generator are coupled to an activation circuit. A switch is coupled to the acoustic generator and the infrared generator. The switch provides activation control of the acoustic generator and the infrared generator. The infrared generator includes a light source operating in the near-infrared (NIR) band. The light source operating in the NIR band provides testing for a gunshot muzzle flash sensor. The infrared generator includes a light source operating in the mid-infrared (MIR) band. The light source operating in the MIR band provides testing for a passive infrared (PIR) sensor.

Abstract: A battery system has a plurality of battery cells including a first battery cell. Each battery cell includes a casing enclosing an anode and a cathode. The battery system also includes a first fluid circulation system with a plurality of fluid conduits including a first fluid conduit that is adjacent to the first battery cell, where the first fluid circulation system is configured to circulate a first fluid through the battery system in a first direction. The battery system also includes a second fluid circulation system with a plurality of fluid conduits including a first fluid conduit that is adjacent to the first fluid conduit of the first fluid circulation system. The second fluid circulation system is configured to circulate a second fluid through the battery system in a second direction that is opposite the first direction.

Abstract: An interface device is structured to be connected in fluid communication with a source of breathing gas and to provide a flow of breathing gas to the airways of a patient. The interface device includes a support (24), a deformable portion (28) situated on the support, and an interface portion (32) situated on the deformable portion and being structured to be engaged with the patient in the vicinity of the airways, with the deformable portion including a plurality of deformable elements (36) that form a lattice structure and that are connected with the support at a plurality of spaced apart points of connection (44) on the support. The interface device may be formed via an additive manufacturing process.

Abstract: Powered patient support apparatuses—such as beds, cots, stretchers, or the like—include a plurality of user controls that allow a caregiver to control the steering and/or driving of one or more powered wheels from multiple different locations around the patient support apparatus (e.g. head end, foot end, and/or the sides). The control is carried out by force sensors that detect both an orientation of the applied forces and a magnitude of the applied forces. Translational and/or rotational movement is effectuated, depending upon the magnitude and direction of the forces, as well as the physical location of the applied force relative to a reference point on the support apparatus, such as the center. One or more object sensors may also be included in the support apparatus to assist in steering and/or navigating.

Abstract: The invention relates to antimicrobial peptides (AMPs). The invention also relates to uses, methods of treatment, pharmaceutical compositions and combinations with antimicrobial agents.

Abstract: The present disclosure provides methods of administering antibodies and antigen-binding fragments thereof that specifically bind to human endothelial lipase (EL) to a subject in need thereof, for example, a subject with cardiovascular disease.

Abstract: A robotic surgical system comprises a surgical tool, a manipulator configured to support the surgical tool, a force/torque sensor to measure forces and torques applied to the surgical tool, and a control system. The control system obtains a three-dimensional milling path for the surgical tool. The control system also receives one or more signals from the force/torque sensor in response to a user manually applying user forces and torques to the surgical tool. The control system determines a commanded pose to which to command the manipulator to advance the surgical tool along the milling path based on a tangential component of the user forces and torques, based on a virtual simulation using virtual constraints, and/or based on other suitable factors to promote guided, manual movement of the surgical tool along the milling path.

Abstract: A heating device includes a heating unit and device electronics. The heating unit is configured to deliver heat to a user's body. The heating unit includes a substrate and a heating element supported by the substrate. The device electronics are coupled to the heating element and are configured to store a first heating profile that includes data indicating how power should be delivered to the heating element over a first period of time. The device electronics are configured to deliver power to the heating element according to the first heating profile. The device electronics are configured to wirelessly receive a second heating profile from an external computing device. The second heating profile includes data indicating how power should be delivered to the heating element over a second period of time. The device electronics are configured to deliver power to the heating element according to the second heating profile.

Abstract: A cell washer is disclosed. The cell washer includes a vessel configured to hold cells. The vessel includes an elongated body including an opening, an inner surface, and a pocket defined by a first inner surface portion of the inner surface disposed between and radially outward relative to a second inner surface portion and a third inner surface portion of the inner surface, and a cavity. The vessel also includes an actuating device capable of causing the vessel to spin about an axis.

Abstract: A sealing arrangement for use in a patient interface device. The sealing arrangement includes a nasal pillow having a sealing surface structured to sealingly engage a surface of the patient at or about the airway. A first magnetic material is disposed in or the nasal pillow. A carrier member is positioned across a nose of the patient. Finally, a second magnetic material is positioned in or on carrier member. The first magnetic material and the second magnetic material magnetically interact in a manner that the sealing surface of the flexible member toward the surface of the patient responsive to the flexible member being disposed at or about the airway and the second magnetic material is disposed at a corresponding position to interact with the first magnetic material.