Abstract: Processor system with a general purpose processor and a cryptographic processor dedicated to performing cryptographic operations and enforcing the security of critical security parameters. The cryptographic processor prevents exposure of critical security parameters outside the cryptographic processor itself, and instead implements a limited scripting engine, which can be used by the general purpose processor to execute operations that require the critical security parameters.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: Frequency-based mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A laser modulator may introduce frequency modulation to laser light to generate a homogeneous illumination field due to increased mode mixing in the optical fiber.

Abstract: Methods and systems are provided for providing passive boost pressure monitoring for slow response with higher confidence. A response time of a boost pressure feedback control loop following a boost pressure deviation that is triggered by either system disturbances or operator torque demand is monitored. Slow boost behavior is correlated with boost control degradation affecting drivability and emissions.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A device may include a physically unclonable function (PUF) source that has at least one fuse embedded in the device. The PUF source may be responsive to an input for transmitting a signal through the fuse and providing a PUF value based on a measurement of such signal. The device also has circuitry that is configured to modify the fuse by transmitting a signal of sufficiently high current or voltage through the fuse to change its resistance, thereby changing a response of the PUF source to the input.

Abstract: A transaction device includes a bootloader that a processing unit executes during device startup. The bootloader causes the processing unit to access values from a persistent memory that are relevant to whether a glitch has occurred on a power supply for the processing unit. Based on the values that are acquired from the persistent memory, the processing unit may implement countermeasures, such as disabling certain device operations or delaying the device booting process.

Abstract: A patient monitor is disclosed for detecting patient movement or abnormal breathing. Images of a patient are obtained by a stereoscopic camera. These images are then processed by a 3D position determination module which determines measurements indicative of positions of at least part of a patient. The obtained measurements are then passed to a model generation module which generates a breathing model of the variation in position of the at least part of a patient during a breathing cycle. Subsequently abnormal breathing or patient movement can be detected by processing further images obtained by the stereoscopic camera to determine more measurements indicative of positions of at least part of a patient. These measurements are then compared with a stored breathing model by a comparison module.

Abstract: A device may include a physically unclonable function (PUF) source that has at least one fuse embedded in the device. The PUF source may be responsive to an input for transmitting a signal through the fuse and providing a PUF value based on a measurement of such signal. The device also has circuitry that is configured to modify the fuse by transmitting a signal of sufficiently high current or voltage through the fuse to change its resistance, thereby changing a response of the PUF source to the input.

Abstract: An electronic device may include a printed circuit board having a physically unclonable function (PUF) source. The electronic device may also include an integrated circuit (IC) chip positioned on the printed circuit board, and the first PUF source may be embedded in or formed on the printed circuit board external to the IC chip. The IC chip has processing circuitry that is configured to determine PUF data based on the PUF source. The processing circuitry is further configured to determine a cryptographic key or authentication token based on the PUF data and to perform at least one secure operation using the cryptographic key or authentication token.

Abstract: A patient monitor is disclosed for detecting patient movement or abnormal breathing. Images of a patient are obtained by a stereoscopic camera. These images are then processed by a 3D position determination module which determines measurements indicative of positions of at least part of a patient. The obtained measurements are then passed to a model generation module which generates a breathing model of the variation in position of the at least part of a patient during a breathing cycle. Subsequently abnormal breathing or patient movement can be detected by processing further images obtained by the stereoscopic camera to determine more measurements indicative of positions of at least part of a patient. These measurements are then compared with a stored breathing model by a comparison module.

Abstract: Methods and systems are provided for providing passive boost pressure monitoring for slow response with higher confidence. A response time of a boost pressure feedback control loop following a boost pressure deviation that is triggered by either system disturbances or operator torque demand is monitored. Slow boost behavior is correlated with boost control degradation affecting drivability and emissions.

Abstract: An example laser probe comprises one or more fibers extending from a proximal end of the laser probe to at least near a distal end of the laser probe, where the proximal end of the laser probe is configured to be coupled to a laser source via an adapter interface, and a cannula having a distal end and surrounding the one or more fibers along at least a portion of the laser probe at or near the distal end of the laser probe. The laser probe further comprises one or more lens elements, where each lens element is fused to or formed directly on the distal end of a corresponding one of the one or more fibers. In some embodiments, the laser probe is a multi-fiber, multi-spot laser probe, e.g., comprising four or more fibers and four or more corresponding lens elements.

Abstract: To address the issue of securely joining thin sections of magnesium housing, a computing device with a housing, a metal strip, and a plastic interlock structure is provided. The housing may include adjacently arranged first and second metal sections separated by a void. The metal strip may have a hole with an undercut region formed therein, and it may be joined to a surface of one of the metal sections. The plastic interlock structure may be positioned at least partially in the void, and the metal strip may be embedded in the plastic interlock structure to strengthen the joint between the metal sections of the housing. The plastic interlock structure may physically and electrically isolate adjacent metal sections from one another to form an antenna that permits transmission of radio waves.

Abstract: To address the issue of securely joining thin sections of magnesium housing, a computing device with a housing, a metal strip, and a plastic interlock structure is provided. The housing may include adjacently arranged first and second metal sections separated by a void. The metal strip may have a hole with an undercut region formed therein, and it may be joined to a surface of one of the metal sections. The plastic interlock structure may be positioned at least partially in the void, and the metal strip may be embedded in the plastic interlock structure to strengthen the joint between the metal sections of the housing. The plastic interlock structure may physically and electrically isolate adjacent metal sections from one another to form an antenna that permits transmission of radio waves.

Abstract: Described herein are a wearable apparatus and methods for detecting the presence of a targeted substance in a liquid. For example, the wearable apparatus can be a fingernail that detects illicit drugs in a beverage. The wearable apparatus comprises a detection layer comprising an indicator that is configured to display a signal upon the detection of an interaction with the targeted substance. In some examples, the wearable apparatus can include a lateral flow assay.

Abstract: Described herein are apparatus and methods for detecting substances of abuse or other analytes in liquids. For example, the apparatus and methods described herein can be used for real-time detection of analytes, such as substances of abuse. The methods comprise providing a detection area comprising a chromatographic membrane capable of receiving the liquid and allowing for migration of the liquid, the chromatographic membrane comprising an anti-analyte antibody-particle conjugate, an analyte-conjugate protein at a test line; exposing at least the first location of the apparatus to the liquid; and determining whether an interaction between the analyte-conjugate protein and the liquid occurs to detect the presence of the analyte. The chromatographic membrane may further comprise an anti-species antibody at a control line.

Abstract: Processor system with a general purpose processor and a cryptographic processor dedicated to performing cryptographic operations and enforcing the security of critical security parameters. The cryptographic processor prevents exposure of critical security parameters outside the cryptographic processor itself, and instead implements a limited scripting engine, which can be used by the general purpose processor to execute operations that require the critical security parameters.

Abstract: Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.

Abstract: Fiber-based mode mixing techniques may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibrating fiber mechanism may impart mechanical motion to a portion of the optical fiber to generate a homogeneous illumination field from a coherent light source.