Patents by Inventor Ryuji Ueno

Ryuji Ueno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140235665
    Abstract: An object of the present invention is to provide an anti-constipation composition containing a halogenated-bi-cyclic compound as an active ingredient in a ratio of bi-cyclic/mono-cyclic structure of at least 1:1. The halogenated-bi-cyclic compound is represented by Formula (I): where X1 and X2 are preferably both fluorine atoms. The composition can be used to treat constipation without substantive side-effects, such as stomachache.
    Type: Application
    Filed: April 30, 2014
    Publication date: August 21, 2014
    Applicant: SUCAMPO AG
    Inventor: Ryuji UENO
  • Patent number: 8779187
    Abstract: The present invention discloses a soft gelatin capsule formulation of a 15-keto-prostaglandin compound, which comprises: a soft gelatin capsule shell comprising gelatin and sugar alcohol as a plasticizer, and a mixture comprising a 15-keto-prostaglandin compound and a pharmaceutically acceptable vehicle which is filled in the shell. By encapsulating the 15-keto-prostaglandin compound in the specified soft gelatin capsule shell, stability of the compound is significantly improved.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: July 15, 2014
    Assignees: Sumcampo AG, R-Tech Ueno, Ltd.
    Inventors: Yukiko Hashitera, Ryu Hirata, Yasuhiro Harada, Ryuji Ueno
  • Publication number: 20140194497
    Abstract: Provided is a composition for scalp and hair treatment, including a menthol derivative and a prostaglandin compound having two hetero atoms at the 15 position. The composition of the present invention is effective not only for preventing dandruff and itchy scalp but also for preventing or treating hair loss, baldness, or hair thinness.
    Type: Application
    Filed: February 6, 2014
    Publication date: July 10, 2014
    Applicant: R-TECH Ueno, Ltd.
    Inventors: Masato IINO, Satoshi YAMAKI, Satoshi NAKANISHI, Masahiro TAJIMA, Ryuji UENO
  • Publication number: 20140171496
    Abstract: The present invention provides a method and composition for promoting hair growth in a mammal which comprises a prostaglandin compound having two hetero atoms at the 15 position as an active ingredient thereof.
    Type: Application
    Filed: February 7, 2014
    Publication date: June 19, 2014
    Applicant: R-Tech Ueno, Ltd.
    Inventors: Ryuji UENO, Tsuyoshi HABE, Takashi SEKIDA
  • Patent number: 8748454
    Abstract: An object of the present invention is to provide an anti-constipation composition containing a halogenated-bi-cyclic compound as an active ingredient in ratio of bi-cyclic/mono-cyclic structure of at least 1:1. The halogenated-bi-cyclic compound is represented by Formula (I): where X1 and X2 are preferably both fluorine atoms. The composition can be used to treat constipation with out substantive side-effects, such as stomachache.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: June 10, 2014
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Patent number: 8748481
    Abstract: The present invention relates to a method for the long term treatment of gastrointestinal disorders in a human subject, which comprises administering an effective amount of a halogenated prostaglandin compound and/or its tautomer to the subject. The method induces substantially no electrolyte shifting during the term of the treatment. The compound used in the present invention can improve quality of life in the human subjects with gastrointestinal disorders, are similarly effective in treating male and female subjects, and also effective in a human subject aged even 65 years and older.
    Type: Grant
    Filed: September 1, 2005
    Date of Patent: June 10, 2014
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Publication number: 20140131121
    Abstract: In an electric vehicle, a power unit is installed in an internal space region of a tire of each of front and rear wheels. The unit has a plurality of power elements arranged on an inner peripheral surface of a ground contact portion of the tire. Each of the elements includes a core made of a permalloy, and a power coil wound around the core. When a periodically-changing magnetic field is generated in a region above a road by an electric supply arrangement installed in the road, each of the elements generates electric power. This electric power is supplied to a motor of the vehicle through a power distribution system. The motor drives front wheels. The electric vehicle can continuously run over long distances without charging a battery at a buttery station.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Inventors: Ryuji UENO, Misako NAKATA
  • Patent number: 8686035
    Abstract: The present invention provides a method and composition for promoting hair growth in a mammal which comprises a prostaglandin compound having two hetero atoms at the 15 position as an active ingredient thereof.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: April 1, 2014
    Assignee: R-Tech Ueno, Ltd.
    Inventors: Ryuji Ueno, Tsuyoshi Habe, Takashi Sekida
  • Patent number: 8673973
    Abstract: Provided is a method for treating ocular hypertension and glaucoma with reduced side effects such as keratoconjunctive disorders and macular edema, which comprises administering an ophthalmic composition comprising latanoprost as an active ingredient thereof to a subject in need of said treatment, wherein the ophthalmic composition contains substantially no benzalkonium chloride.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: March 18, 2014
    Assignee: Sucampo AG (USA) Inc.
    Inventor: Ryuji Ueno
  • Patent number: 8669284
    Abstract: Disclosed is a method for stabilizing a pharmaceutically active bi-cyclic compound of formula (I): comprising the step of: admixing the same with a polyol and/or a fatty acid ester other than glyceride and a composition obtained by the method. In addition a soft gelatin capsule formulation of the compound of formula (I) obtained by incorporating the compound in a soft gelatin capsule shell comprising gelatin and a polyol plasticizer.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: March 11, 2014
    Assignees: Sucampo AG, R-Tech Ueno, Ltd.
    Inventors: Ryu Hirata, Yasuhiro Harada, Ryuji Ueno
  • Publication number: 20140066506
    Abstract: Disclosed is a method for treating macular degeneration in a mammalian subject, which includes administering to the subject in need thereof an effective amount of a 15-keto-prostaglandin compound such as 13,14-dihydro-15-keto-20-ethyl-prostaglandin F2? isopropyl ester.
    Type: Application
    Filed: November 5, 2013
    Publication date: March 6, 2014
    Applicant: SUCAMPO AG
    Inventors: Ryuji UENO, John CUPPOLETTI
  • Patent number: 8662221
    Abstract: In an electric vehicle, a power unit is installed in an internal space region of a tire of each of front and rear wheels. The unit has a plurality of power elements arranged on an inner peripheral surface of a ground contact portion of the tire. Each of the elements includes a core made of a permalloy, and a power coil wound around the core. When a periodically-changing magnetic field is generated in a region above a road by an electric supply arrangement installed in the road, each of the elements generates electric power. This electric power is supplied to a motor of the vehicle through a power distribution system. The motor drives front wheels. The electric vehicle can continuously run over long distances without charging a battery at a buttery station.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: March 4, 2014
    Assignee: Rusk Intellecutal Reserve AG
    Inventors: Ryuji Ueno, Misako Nakata
  • Publication number: 20140039058
    Abstract: The present invention relates to an ophthalmic solution comprising a prostaglandin compound and viscosity-increasing compound. The ophthalmic solution of the invention is excellent in stability and can provide long lasting and increased effect when administrated topically to the eyes of a patient.
    Type: Application
    Filed: October 8, 2013
    Publication date: February 6, 2014
    Applicant: SUCAMPO AG
    Inventor: Ryuji UENO
  • Publication number: 20140031428
    Abstract: The present invention provides a novel fatty acid derivative. The present invention also provides a method for treating schizophrenia in a mammalian subject, which comprises administering to the subject in need thereof an effective amount of a fatty acid derivative.
    Type: Application
    Filed: September 26, 2013
    Publication date: January 30, 2014
    Applicant: SUCAMPO AG
    Inventor: Ryuji UENO
  • Patent number: 8609729
    Abstract: Disclosed is a method for treating macular degeneration in a mammalian subject, which comprises administering to the subject in need thereof an effective amount of a 15-keto-prostaglandin compound such as 13,14-dihydro-15-keto-20-ethyl-prostaglandin F2? isopropyl ester.
    Type: Grant
    Filed: April 12, 2010
    Date of Patent: December 17, 2013
    Assignee: Sucampo AG
    Inventors: Ryuji Ueno, John Cuppoletti
  • Patent number: 8592483
    Abstract: The present invention provides a novel fatty acid derivative. The present invention also provides a method for treating schizophrenia in a mammalian subject, which comprises administering to the subject in need thereof an effective amount of a fatty acid derivative.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: November 26, 2013
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Patent number: 8580851
    Abstract: The present invention relates to an ophthalmic solution comprising a prostaglandin compound and viscosity-increasing compound. The ophthalmic solution of the invention is excellent in stability and can provide long lasting and increased effect when administrated topically to the eyes of a patient.
    Type: Grant
    Filed: April 21, 2005
    Date of Patent: November 12, 2013
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Patent number: 8569279
    Abstract: Disclosed is a method for modulating a claudin-mediated function in a mammalian subject which comprises administering to a subject in need thereof an effective amount of a specific fatty acid derivative. The application also discloses a method for treating a dermatological disease and a method for modulating an expression of a claudin in a mammalian subject using the same fatty acid derivative as above.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: October 29, 2013
    Assignees: Sucampo AG, Osaka University
    Inventors: Ryuji Ueno, Sachiko Tsukita
  • Publication number: 20130281637
    Abstract: A fatty acid derivative-polymer conjugate including a conjugate comprising a fatty acid derivative and an alkyl substituted polylactide compound is provided. A pharmaceutical composition comprising the conjugate is also provided.
    Type: Application
    Filed: April 19, 2013
    Publication date: October 24, 2013
    Applicant: Sucampo AG
    Inventors: Ryuji UENO, Peter LICHTLEN, Robert GURNY, Michael MOLLER
  • Publication number: 20130281638
    Abstract: A tricycle compound-polymer conjugate including a conjugate comprising a tricyclo compound and an alkyl substituted polylactide compound is provided. A pharmaceutical composition comprising the conjugate is also provided.
    Type: Application
    Filed: April 19, 2013
    Publication date: October 24, 2013
    Applicant: SUCAMPO AG
    Inventors: Ryuji UENO, Peter LICHTLEN, Robert GURNY, Michael MOLLER