Abstract: A biguanide derivative compound with N1-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a pharmaceutical composition containing the same as an active ingredient are provided. The biguanide derivative may exhibit excellent effect on activation of AMPK? and inhibition of cancer cell proliferation in a low dose, compared to conventional drugs, and thus, may be useful to treat diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovarian syndrome, metabolic syndrome, cancer, etc.

Abstract: A method and an apparatus for providing a character input interface are provided. The method for providing a character input interface in a terminal having a touchscreen, includes simultaneously displaying a first keyboard on a first region and a second keyboard including second keyboard language selection keys on a second region by the touchscreen in a character inputting mode; and changing a language of the second keyboard to a language corresponding to a second touched keyboard language selection key touched while maintaining a language of the first keyboard when input touching the second keyboard language key is received.

Abstract: The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.

Abstract: A method of erasing a memory device, the method of erasing the memory device including: performing, in a first erase period, a first erase operation on memory cells respectively connected to a plurality of word lines, wherein at least one of the memory cells, which is included in a memory block, is not erase-passed; determining, after the first erase period, an erase operation speed by applying a verify voltage to at least one of the plurality of word lines, and determining an effective erasing time for each word line based on the determined erase operation speed; and performing, in a second erase period, a second erase operation on the memory cells respectively connected to the plurality of word lines based on the determined effective erasing times.

Abstract: A memory device can include a memory block operatively connected to a common source line and a plurality of bit lines, wherein the memory block includes first and second sub-blocks each having a respective position in the memory block relative to the common source line and the plurality of bit lines. The memory device can be operated by receiving a command and an address from outside the memory device and performing a precharge operation on the memory block in response to the command, using a first precharge path through the memory block or a second precharge path through the memory block based on the respective position of the first or second sub-block that includes a word line that is configured to activate responsive to the address.

Abstract: A nonvolatile memory device performs a method which includes: causing a ready/busy signal pin of the nonvolatile memory device to indicate that the nonvolatile memory device is in a precharge busy state wherein the nonvolatile memory device is not available to perform memory access operations for its nonvolatile memory cells; applying one or more word line precharge voltages to one or more selected word lines among a plurality of word lines of the nonvolatile memory device to precharge the selected word lines; and, after at least a portion of the precharge operation, causing the ready/busy signal pin to transition from indicating the precharge busy state, to indicating that the nonvolatile memory device is in a ready state wherein the nonvolatile memory device is available to perform memory access operations for its nonvolatile memory cells.

Abstract: A non-volatile memory device includes: a memory cell array including a memory cell string including a ground selection transistor and a plurality of serially connected non-volatile memory cells; a ground selection line connected to the ground selection transistor and a plurality of word lines connected to the plurality of memory cells; a voltage generator configured to generate a program verification voltage and a read voltage applied to the plurality of word lines; and a control circuit configured to control a compensation for the program verification voltage based on a program verification temperature offset, and control a to compensation for the read voltage based on a read temperature offset.

Abstract: A biguanide derivative compound with N1-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a pharmaceutical composition containing the same as an active ingredient are provided. The biguanide derivative may exhibit excellent effect on activation of AMPK? and inhibition of cancer cell proliferation in a low dose, compared to conventional drugs, and thus, may be useful to treat diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovarian syndrome, metabolic syndrome, cancer, etc.

Abstract: A menu execution apparatus and method for conveniently providing a menu in a wireless terminal are provided. The apparatus includes a pointer unit for indicating a specific object in a menu execution recognition mode. A camera photographs the object indicated by the pointer unit in the menu execution recognition mode. A controller controls an operation for recognizing the object indicated by the pointer unit and photographed by the camera and displaying a menu for controlling the recognized object.

Abstract: A method and apparatus for easily restricting a use right and improving use convenience in a mobile terminal are provided. The method includes displaying a profile list for selecting a set operation mode of the mobile terminal from the displayed profile list; setting an operation mode of the mobile terminal as the selected operation mode, when the set operation mode is selected from the displayed profile list; and displaying a screen associated with the selected operation mode, wherein the set operation mode includes an open mode to use all functions of the mobile terminal and a limited mode to use only set functions.

Abstract: A nonvolatile memory device performs a method which includes: causing a ready/busy signal pin of the nonvolatile memory device to indicate that the nonvolatile memory device is in a precharge busy state wherein the nonvolatile memory device is not available to perform memory access operations for its nonvolatile memory cells; applying one or more word line precharge voltages to one or more selected word lines among a plurality of word lines of the nonvolatile memory device to precharge the selected word lines; and, after at least a portion of the precharge operation, causing the ready/busy signal pin to transition from indicating the precharge busy state, to indicating that the nonvolatile memory device is in a ready state wherein the nonvolatile memory device is available to perform memory access operations for its nonvolatile memory cells.

Abstract: A biguanide derivative compound with N1-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof a method of preparing the same, and a pharmaceutical composition containing the same as an active ingredient are provided. The biguanide derivative may exhibit excellent effect on activation of AMPK? and inhibition of cancer cell proliferation in a low dose, compared to conventional drugs, and thus, may be useful to treat diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovarian syndrome, metabolic syndrome, cancer, etc.

Abstract: A method and an apparatus for providing a character input interface are provided. The method for providing a character input interface in a terminal having a touchscreen, includes simultaneously displaying a first keyboard on a first region and a second keyboard including second keyboard language selection keys on a second region by the touchscreen in a character inputting mode; and changing a language of the second keyboard to a language corresponding to a second touched keyboard language selection key touched while maintaining a language of the first keyboard when input touching the second keyboard language key is received.

Abstract: A non-volatile memory device includes: a memory cell array including a memory cell string including a ground selection transistor and a plurality of serially connected non-volatile memory cells; a ground selection line connected to the ground selection transistor and a plurality of word lines connected to the plurality of memory cells; a voltage generator configured to generate a program verification voltage and a read voltage applied to the plurality of word lines; and a control circuit configured to control a compensation for the program verification voltage based on a program verification temperature offset, and control a to compensation for the read voltage based on a read temperature offset.

Abstract: A method and an apparatus for providing a character input interface are provided. The method for providing a character input interface in a terminal having a touchscreen, includes simultaneously displaying a first keyboard on a first region and a second keyboard including second keyboard language selection keys on a second region by the touchscreen in a character inputting mode; and changing a language of the second keyboard to a language corresponding to a second touched keyboard language selection key touched while maintaining a language of the first keyboard when input touching the second keyboard language key is received.

Abstract: A character input system and method is provided that enables a user to input and edit block characters via a touch-based electronic device, with a limited number of input motions. The character input method includes receiving a first interaction, displaying a first character in response to the first interaction, receiving a second interaction successively after the first interaction, identifying a second character that is formed by combining the first character with a character according to the second interaction, and displaying the second character instead of the first character.

Abstract: A method and apparatus for easily restricting a use right and improving use convenience in a mobile terminal are provided. The method includes displaying a profile list for selecting a set operation mode of the mobile terminal from the displayed profile list; setting an operation mode of the mobile terminal as the selected operation mode, when the set operation mode is selected from the displayed profile list,; and displaying a screen associated with the selected operation mode, wherein the set operation mode includes an open mode to use all functions of the mobile terminal and a limited mode to use only set functions.

Abstract: An N1-cyclic amine-N5-substituted phenyl biguanide derivative of Formula 1 or a pharmaceutically acceptable salt thereof, a method of manufacturing the same, and a pharmaceutical composition including the biguanide derivative or the pharmaceutically acceptable salt thereof as an active ingredient are provided. The biguanide derivatives have an effect of inhibiting cancer cell proliferation and also exhibit anticancer activity including inhibition of cancer metastasis and cancer recurrence, because they are effective in activating AMPK, which is associated with the control of energy metabolism, even when administered in a small dose compared with conventional drugs. Also, the biguanide derivatives are highly effective at lowering blood glucose and lipid concentration by AMPK activation, thus they may be effectively used to treat diabetes mellitus, obesity, hyperlipemia, hypercholesterolemia, fatty liver, coronary artery disease, osteoporosis, polycystic ovary syndrome and metabolic syndrome.

Abstract: A method and an apparatus are provided for providing a character input interface in a terminal having a touchscreen. A single keyboard is displayed in a keyboard area of the touchscreen. A first keyboard and a second keyboard are simultaneously displayed in place of the single keyboard in the keyboard area, upon detecting selection of a key on the single keyboard. At least one of the first keyboard and the second keyboard includes a plurality of character-type selection keys, and at least one of the plurality of character-type selection keys includes a language selection key. A controlling unit of the terminal changes a type of characters displayed on one of the first keyboard and the second keyboard, upon detecting selection of one of the plurality of character-type selection keys on the one of the first keyboard and the second keyboard.

Abstract: A method and apparatus for easily restricting a use right and improving use convenience in a mobile terminal are provided. The method includes displaying a profile list for selecting a set operation mode of the mobile terminal from the displayed profile list; setting an operation mode of the mobile terminal as the selected operation mode, when the set operation mode is selected from the displayed profile list; and displaying a screen associated with the selected operation mode, wherein the set operation mode includes an open mode to use all functions of the mobile terminal and a limited mode to use only set functions.