Abstract: A device for performing a surgical procedure can comprise a shaft extending from a proximal portion to a distal portion, a light conductor extending at least partially through the shaft to be exposed at the distal portion, and a damage mitigator positioned to receive light from the light conductor to discharge the light from the device. A method of preventing damage to an optical fiber in a medical device having laser treatment capabilities can comprise emitting a laser beam from the optical fiber, fragmenting a biological stone with the laser beam, and mitigating damage to the optical fiber from fragmentation of the biological stone.

Abstract: Systems, devices, and methods for determining a distance between a distal end of an endoscope and a target during an endoscopic procedure are disclosed. A surgical laser feedback control system comprises a feedback analyzer and a controller. The feedback analyzer can receive at least two reflected signals from a target in response to electromagnetic radiation directed at the target. The at least two reflected signals correspond to respective different distances between a distal end of a device of a surgical laser system and the target. The feedback analyzer can determine a distance between the distal end of the device of the surgical laser system and the target based on the at least two reflected signals. The controller can generate a control signal to the surgical laser system to perform a predetermined operation based on the determined distance.

Abstract: A laser tissue ablation system can include an optical fiber, with a distal end being extendible from an endoscope body of an endoscope. The optical fiber can deliver therapeutic laser light from the distal end of the optical fiber toward a target site, and receive return light into the distal end of the optical fiber. The laser tissue ablation system can include a sensor that can spectrally measure the return light. The laser tissue ablation system can include processor circuitry that can form a first determination, from the spectral measurement of the return light, whether flashing event light is present in the return light. The flashing event light can be generated when a flashing event occurs at the distal end of the optical fiber. The processor circuitry can generate, in response to the first determination, a flashing event data signal that indicates whether the flashing event has occurred.

Abstract: Systems, devices, and methods for endoscopic mapping of a target and tracking of endoscope locations inside a subject's body during a procedure are disclosed. An exemplary system comprises an imaging system configured to capture an endoscopic image of the target that includes a footprint of an aiming beam directed at the target, and a video processor configured to identifying one or more landmarks from the captured endoscopic image and determine their respective locations relative to the aiming beam footprint, and generate a target map by integrating a plurality of endoscopic images based on landmarks identified from one or more of the plurality of endoscopic images. The target map can be used to track endoscope location during an endoscopic procedure.

Abstract: Systems, devices, and methods for endoscopic mapping of a target and tracking of endoscope locations inside a subject's body during a procedure are disclosed. An exemplary system comprises an imaging system configured to capture an endoscopic image of the target that includes a footprint of an aiming beam directed at the target, and a video processor configured to identifying one or more landmarks from the captured endoscopic image and determine their respective locations relative to the aiming beam footprint, and generate a target map by integrating a plurality of endoscopic images based on landmarks identified from one or more of the plurality of endoscopic images. The target map can be used to track endoscope location during an endoscopic procedure.

Abstract: Systems, devices, and methods for delivering laser energy directed toward target tissue using a spectroscopic feedback. An exemplary laser feedback control system comprises a feedback analyzer to receive a signal from a target tissue using a spectroscopic sensor, and a laser controller to determine whether the received signal generally equals a first preset. If the received signal meets the first preset, the laser controller can send a control signal to a laser system to change from a first state to a second state of the first laser system. The laser system can deliver laser energy via an optical fiber towards the target tissue.

Abstract: Systems, devices, and methods for delivering laser energy directed toward target tissue using a spectroscopic feedback. An exemplary laser feedback control system comprises a feedback analyzer to receive a signal from a target tissue using a spectroscopic sensor, and a laser controller to determine whether the received signal generally equals a first preset. If the received signal meets the first preset, the laser controller can send a control signal to a laser system to change from a first state to a second state of the first laser system. The laser system can deliver laser energy via an optical fiber towards the target tissue.

Abstract: Systems, devices, and methods for determining advancement of a surgical laser fiber in an endoscope and providing interlocking feedback for the surgical laser are disclosed. An exemplary method includes directing light from a distal end of an endoscope to a target, optically detecting an amount of the light reflected from the target, transmitting the optically detected amount of light through a laser fiber extending through a working channel of the endoscope, determining, based on the optically detected amount of light, a position of a distal end of the laser fiber relative to the distal end of the endoscope, and generating a control signal to the surgical laser system to adjust laser emission through the laser fiber.

Abstract: A probe of a target identification system can be extended via a first lumen of a viewing instrument, such as for illuminating an area beyond a distal end of the viewing instrument via an optical path of the viewing instrument. An optical response to the illumination of the area can be received via an optical path of the probe and can be split from other optical signals of the optical path. The optical response information can be used to identify characteristics of a target and to adjust parameters of a working instrument such as a working instrument contemporaneously using the probe.

Abstract: A method of identifying an illumination light source in a surgical system comprises steps of receiving a signal from a target after the target is illuminated by the illumination light source, performing spectroscopic analysis of the received signal, and based at least in part on the spectroscopic analysis, determining a characteristic of the illumination light source. A method of treating a target comprises receiving a signal from the target after the target is illuminated by an illumination light source, performing spectroscopic analysis of the received signal, based at least in part on the spectroscopic analysis, determining a first characteristic of the illumination light source and a second characteristic of the target, and based at least in part on the determined characteristics of the illumination light source and the target, operating a surgical system to treat the target.

Abstract: A system for spectroscopic signal detection can comprise a spectrometer, a light source emitter configurable to emit a first signal toward a target, and an aiming light source emitter configurable to emit a second signal having a visible spectrum toward the target. The system can include a first optical component such as a filter for attenuating or removing noise associated with the second signal from a third signal from the target back to the spectrometer.

Abstract: Systems, devices, and methods for determining advancement of a surgical laser fiber in an endoscope and providing interlocking feedback for the surgical laser are disclosed. An exemplary method includes directing light from a distal end of an endoscope to a target, optically detecting an amount of the light reflected from the target, transmitting the optically detected amount of light through a laser fiber extending through a working channel of the endoscope, determining, based on the optically detected amount of light, a position of a distal end of the laser fiber relative to the distal end of the endoscope, and generating a control signal to the surgical laser system to adjust laser emission through the laser fiber.

Abstract: Systems, devices, and methods for identifying a target in a body using a spectroscopic feedback from the target are disclosed. An exemplary surgical feedback control system comprises a feedback analyzer configured to receive a reflected signal from a target in response to electromagnetic radiation directed at a target, and a controller in operative communication with the feedback analyzer. The controller can generate a control signal to a surgical system to perform a predetermined operation based upon the received reflected signal, including determining a composition of the target, or programming a laser setting to direct laser energy to the target.

Abstract: Systems, devices, and methods for delivering laser energy to a target in an endoscopic procedure are disclosed. An exemplary method comprises providing a first laser pulse train and a different second laser pulse train emitting from a distal end of an endoscope and incident on a target. The first laser pulse train has a first laser energy level, and the second laser pulse train has a second laser energy level higher than the first laser energy level. In an example, the first laser pulse train is used to form cracks on a surface of a calculi structure, and the second laser pulse train causes fragmentation of the calculi structure after the cracks are formed.

Abstract: Systems, devices, and methods for identifying a target in a body using a spectroscopic feedback from the target are disclosed. An exemplary surgical feedback control system comprises a feedback analyzer configured to receive a reflected signal from a target in response to electromagnetic radiation directed at a target, and a controller in operative communication with the feedback analyzer. The controller can generate a control signal to a surgical system to perform a predetermined operation based upon the received reflected signal, including determining a composition of the target, or programming a laser setting to direct laser energy to the target.

Abstract: A laser can be controlled based on different tissue compositions, such as in real time. After a first time period, a first composition of a in vivo target site can be identified. Based on the first composition, a plurality of lasers can be controlled to emit light at a first wavelength where controlling includes activating a first combination of the plurality of lasers. After a second time period, a second composition of the in vivo target site different from the first composition can be identified. Based on the second composition, a plurality of lasers can be controlled to emit light at a second wavelength, such as can include activating a second combination of the plurality of lasers. The first combination of the plurality of lasers can be different from the second combination of the plurality of lasers.

Abstract: Various aspects of methods, systems, and use cases may be used to deploy a light source to a targeted organ location via a working channel of an endoscope, such as in a manner that leaves the working channel free for use by another instrument and that can avoid requiring an additional channel, beyond the working channel, for illumination of a target region.

Abstract: A method for determining a characteristic of material at a target is provided. A target is illuminated with a pulsed light source. A fluorescence signal from the target when the pulsed light source is an “off” state is then sensed. Based on analysis of the fluorescence signal, a characteristic of material at the target is identified. A device can then be controlled based on the identified characteristic of the material at the target.

Abstract: Systems, devices, and methods for delivering laser energy to a target in an endoscopic procedure are disclosed. An exemplary method comprises providing a first laser pulse train and a different second laser pulse train emitting from a distal end of an endoscope and incident on a target. The first laser pulse train has a first laser energy level, and the second laser pulse train has a second laser energy level higher than the first laser energy level. In an example, the first laser pulse train is used to form cracks on a surface of a calculi structure, and the second laser pulse train causes fragmentation of the calculi structure after the cracks are formed.

Abstract: A probe of a target identification system can be extended via a first lumen of a viewing instrument, such as for illuminating an area beyond a distal end of the viewing instrument via an optical path of the viewing instrument. An optical response to the illumination of the area can be received via an optical path of the probe and can be split from other optical signals of the optical path. The optical response information can be used to identify characteristics of a target and to adjust parameters of a working instrument such as a working instrument contemporaneously using the probe.