Abstract: A closure includes: a body having a skirt wall in which an internal thread is formed; and a cylindrical tamper evident bottom portion which is connected to the skirt wall via a plurality of breakable bridge portions, and in which an engaging pieces to be engaged with an engaging jaw portion is disposed on an inner peripheral surface of the tamper evident bottom portion. A protruding piece protruding downward is disposed on the skirt wall of the body. An unbroken connecting piece is disposed to connect the skirt wall of the body and the tamper evident bottom portion and to allow the body to be moved upward with respect to the tamper evident bottom portion. An extending portion is formed at an engaging piece serving as the engaging pieces at least in an angle region where the protruding piece is present.

Abstract: [Object] To provide a synthetic resin cap of a structure that is further improved in convenience when drinking while suppressing falling or loss of the cap when a container is opened. [Solving Means] A synthetic resin cap as a specific example of the present invention has a tamper-evident band to be fitted on an outer peripheral surface of a container mouth portion of a container, and a cap main body having a skirt wall and a top plate, and including, in the skirt wall, a fixing rib coupled with the tamper-evident band via a weakened portion and a strap portion and extending to a radially outer side of the skirt wall. The fixing rib is formed from a first inclined portion that flares downwards, and a protrusion portion that is disposed below the first inclined portion.

Abstract: A closure includes: a body having a skirt wall in which an internal thread is formed; and a cylindrical tamper evident bottom portion which is connected to the skirt wall via a plurality of breakable bridge portions, and in which an engaging means to be engaged with an engaging jaw portion is disposed on an inner peripheral surface of the tamper evident bottom portion. A protruding piece protruding downward is disposed on the skirt wall of the body. An unbroken connecting piece is disposed to connect the skirt wall of the body and the tamper evident bottom portion and to allow the body to be moved upward with respect to the tamper evident bottom portion. An extending portion is formed at an engaging piece serving as the engaging means at least in an angle region where the protruding piece is present.

Abstract: To provide a system capable of evaluating a deficiency and/or a lowered function of extrinsic coagulation factors or intrinsic coagulation factors with high sensitivity by adding new procedures and apparatuses to a blood coagulation system analysis procedure, an apparatus, or the like. A blood coagulation system analysis system includes a blood coagulation system measurement apparatus that performs blood coagulation system measurement of a blood sample; and a blood coagulation system analysis apparatus including a coagulation parameter extraction unit that extracts a coagulation parameter from a measurement result by the blood coagulation system measurement apparatus, and a blood coagulation evaluation unit that evaluates a level of blood coagulation of the blood sample on the basis of the coagulation parameter, the measurement by the blood coagulation system measurement apparatus being performed under an extrinsic system acceleration condition and an intrinsic system acceleration condition.

Abstract: Disclosed are a blood coagulation system examination module, a blood coagulation system examination system, and a blood coagulation system examination method, all of which enable to simply and easily measure thrombin potential with a whole blood sample. The blood coagulation system examination module includes a thrombin potential examination unit configured to examine thrombin potential on the basis of an electrical property of blood as measured at a specific frequency and predetermined time intervals in a predetermined period after reversal of an anticoagulation action working on the blood.

Abstract: To provide a system capable of evaluating a deficiency and/or a lowered function of extrinsic coagulation factors or intrinsic coagulation factors with high sensitivity by adding new procedures and apparatuses to a blood coagulation system analysis procedure, an apparatus, or the like. A blood coagulation system analysis system includes a blood coagulation system measurement apparatus that performs blood coagulation system measurement of a blood sample; and a blood coagulation system analysis apparatus including a coagulation parameter extraction unit that extracts a coagulation parameter from a measurement result by the blood coagulation system measurement apparatus, and a blood coagulation evaluation unit that evaluates a level of blood coagulation of the blood sample on the basis of the coagulation parameter, the measurement by the blood coagulation system measurement apparatus being performed under an extrinsic system acceleration condition and an intrinsic system acceleration condition.

Abstract: The main purpose of the present technology is to provide a technology capable of reducing the risk of erroneous determination while ensuring real-time properties in the measurement of electrical characteristics of a biological sample. In this regard, the present technology provides an electrical characteristics measurement apparatus including: at least a measurement unit that measures electrical characteristics of a biological sample over time; an analysis unit that reviews, in real time during the measurement, data related to a temporal change in the electrical characteristics and analyzes a change in state of the biological sample; and a notification unit that issues notification of an analysis result in the analysis unit at a specific time point, in which the analysis unit detects a predetermined feature point from the data related to the temporal change in the electrical characteristics to use data related to the temporal change in a period before and/or after the predetermined feature point.

Abstract: A flow channel device, a complex permittivity measuring apparatus, and a dielectric cytometry system are provided which can improve the measurement accuracy. A constriction portion having a constricted space is disposed between an inflow port and an outflow port of a flow channel. Electrodes are arranged between the inflow port and the constriction portion and between the outflow port and the constriction portion. The conductance of the constriction portion at a low-limit frequency is less than the combined conductance of an inflow channel portion and an outflow channel portion. The capacitance of the constriction portion at a high-limit frequency is less than the combined capacitance of the inflow channel portion and the outflow channel portion.

Abstract: To provide a technique which is useful in verification of measurement accuracy before measurement in the measurement of electric characteristics of a blood sample. There is provided a sample for measurement of electric characteristics at least including a liquid containing a blood coagulation factor, and micro particles. The density of each of the micro particles is different from the density of the liquid containing the blood coagulation factor. In addition, there is provided an electric characteristic measuring apparatus and an electric characteristic measuring method as well each using the sample for measurement of electric characteristics.

Abstract: There is provided a microparticle analysis apparatus including a sample channel configured to receive liquid containing a plurality of microparticles, a first pair of electrodes configured to form an alternating electric field in at least a part of the sample channel, a measuring part configured to measure impedance between the first pair of electrodes, an analyzing part configured to calculate property values of the microparticles from the impedance measured in the measuring part, and a determining part configured to determine whether data of the impedance measured in the measuring part is derived from the microparticles.

Abstract: A transmission line substrate includes at least an insulating layer of a predetermined thickness, a pair of conductor layers arranged in a state of being opposed to each other such that the insulating layer is interposed between the conductor layers, the pair of conductor layers functioning as a high-frequency transmission line, and a fault part formed so as to make the conductor layer on one side disconnected, into which a sample to be measured can be introduced.

Abstract: There is provided a microparticle analysis apparatus including a sample channel configured to receive liquid containing a plurality of microparticles, a first pair of electrodes configured to form an alternating electric field in at least a part of the sample channel, a measuring part configured to measure impedance between the first pair of electrodes, an analyzing part configured to calculate property values of the microparticles from the impedance measured in the measuring part, and a determining part configured to determine whether data of the impedance measured in the measuring part is derived from the microparticles.

Abstract: A blood coagulation analysis device and method in which information relating to the coagulability of blood is evaluated based on a change generated in a permittivity measured in a coagulation process of the blood due to addition of a substance that activates or inactivates platelets to the blood.

Abstract: Disclosed herein is a dielectric cytometric apparatus capable of analyzing cells and sorting the cells without adopting an optical analysis method and provides a dielectric cytometric cell sorting method for the apparatus. A stenosis channel allowing a single cell to flow is created on a cell injection section of a micro flow channel device used as a portion of the dielectric cytometric apparatus. A pair of measurement electrodes is created on the stenosis channel and an analyzer connected to the measurement electrodes measures the complex dielectric constant of for every cell passing through the stenosis channel. A electric-field application section provided on the downstream side of the stenosis channel applies an electric field for changing the flow of the cells inside a flow channel on the basis of information on the measured complex dielectric constants so that the cells can be sorted by making use of branch channels.

Abstract: A blood coagulation analysis device and method in which information relating to the coagulability of blood is evaluated based on a change generated in a permittivity measured in a coagulation process of the blood due to addition of a substance that activates or inactivates platelets to the blood.

Abstract: A blood coagulation system analyzing method includes acquiring information relating to the coagulability of blood based on a change generated in a complex permittivity spectrum measured in a coagulation process of the blood due to addition of a substance that activates or inactivates platelets to the blood.

Abstract: A transmission line substrate includes at least an insulating layer of a predetermined thickness, a pair of conductor layers arranged in a state of being opposed to each other such that the insulating layer is interposed between the conductor layers, the pair of conductor layers functioning as a high-frequency transmission line, and a fault part formed so as to make the conductor layer on one side disconnected, into which a sample to be measured can be introduced.

Abstract: A blood coagulation system analyzing method includes acquiring information relating to the coagulability of blood based on a change generated in a complex permittivity spectrum measured in a coagulation process of the blood due to addition of a substance that activates or inactivates platelets to the blood.

Abstract: Disclosed herein is a system for detecting interaction between substances includes a reaction field for allowing the interaction to proceed between the substances, and a voltage application section for applying a voltage to a working electrode arranged facing the reaction field such that a predetermined electrodynamic effect is given to the reaction field. The voltage application section is provided with a section for superimposingly applying two sinusoidal voltages of different frequencies to generate a beat. Also disclosed herein is a method for detecting interaction between substances in a procedure of allowing the interaction to proceed between the substances by making use of a predetermined electrodynamic effect, the method includes the step of applying two sinusoidal voltages of different frequencies superimposingly to generate a beat such that an electrochemical reaction is suppressed in a reaction field where the interaction is allowed to proceed.

Abstract: Disclosed herein is a dielectric cytometric apparatus capable of analyzing cells and sorting the cells without adopting an optical analysis method and provides a dielectric cytometric cell sorting method for the apparatus. A stenosis channel allowing a single cell to flow is created on a cell injection section of a micro flow channel device used as a portion of the dielectric cytometric apparatus. A pair of measurement electrodes is created on the stenosis channel and an analyzer connected to the measurement electrodes measures the complex dielectric constant of for every cell passing through the stenosis channel. A electric-field application section provided on the downstream side of the stenosis channel applies an electric field for changing the flow of the cells inside a flow channel on the basis of information on the measured complex dielectric constants so that the cells can be sorted by making use of branch channels.