Patents by Inventor Shinji Sugihara

Shinji Sugihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10633469
    Abstract: A method for producing a hydroxyl group-containing vinyl ether polymer according to the present invention includes: a step of radical polymerizing at least one vinyl ether selected from vinyl ether having a hydroxyl group represented by the following formula (2): wherein R7 represents an alkylene group which is straight-chained, branched or comprises an alicyclic structure, and p is 1, 2, or 3, in the presence of water as a polymerization solvent and an azo compound represented by the following formula (1) as a polymerization initiator: wherein R1 to R4 each independently represent a hydrogen atom or an alkyl group and R5 and R6 each independently represent an alkoxy group optionally having a substituent group or an alkyl amino group optionally having a substituent group.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: April 28, 2020
    Assignee: Maruzen Petrochemical Co., Ltd.
    Inventors: Shinji Sugihara, Norihiro Yoshida
  • Patent number: 10570232
    Abstract: An alkenyl ether-vinyl ester copolymer contains a repeating unit derived from a hydroxyl group-containing alkenyl ether represented by the following formula (1), and a repeating unit derived from a vinyl ester represented by the following formula (2): where R1, R2, and R3 each independently represents a hydrogen atom or an alkyl group having from 1 to 4 carbon atoms; R4 represents a linear or branched alkylene group having from 2 to 4 carbon atoms; R5 represents an acyl group having from 1 to 20 carbon atoms; and p represents an integer of from 1 to 3. The alkenyl ether-vinyl ester copolymer exhibits temperature responsiveness showing a change in hydrophilicity and hydrophobicity at a prescribed temperature as a critical point and has a lower critical solution temperature to water of from 1° C. to 99° C.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: February 25, 2020
    Assignee: Maruzen Petrochemical Co., Ltd.
    Inventor: Shinji Sugihara
  • Patent number: 10508292
    Abstract: A method of producing a lipid, containing the steps of culturing a transformant obtained by introducing a gene encoding the following protein (a) or (b) into cyanobacteria, and producing a lipid: (a) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and (b) a protein consisting of an amino acid sequence having 60% or more identity with the amino acid sequence of the protein (a), and having ?-ketoacyl-ACP synthase activity.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: December 17, 2019
    Assignee: Kao Corporation
    Inventors: Akihito Kawahara, Shinji Sugihara
  • Patent number: 10487344
    Abstract: A method of producing lipids, containing the steps of: culturing a transformant in which the expression of a gene encoding the following protein (A) or (B) is enhanced, and producing fatty acids or lipids containing these fatty acids as components: (A) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and (B) a protein consisting of an amino acid sequence having 44% or more identity with the amino acid sequence of the protein (A), and having acyltransferase activity.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: November 26, 2019
    Assignee: Kao Corporation
    Inventor: Shinji Sugihara
  • Patent number: 10370478
    Abstract: To provide a method for producing a polymer that is capable of providing an alkenyl ether polymer having a molecular weight, a molecular weight distribution, and a composition that are controlled, with a vinyl ether having a hydroxyl group, and a block copolymer thereof. To provide a polymer obtained by the method as a macro chain transfer agent capable of performing reversible addition fragmentation chain transfer polymerization. Livingness can be imparted to radical polymerization of a hydroxyl group-containing vinyl ether by performing the radical polymerization in the presence of a particular RAFT agent and a radical polymerization initiator, and a block copolymer with another radically polymerizable vinyl monomer can be obtained by using the resulting living polymer as a macro chain transfer agent capable of performing reversible addition fragmentation chain transfer polymerization.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: August 6, 2019
    Assignee: Maruzen Petrochemical Co., Ltd.
    Inventor: Shinji Sugihara
  • Patent number: 10337037
    Abstract: A method of producing lipids, containing the steps of: culturing a transformant in which the expression of a gene encoding the following protein (A) or (B) is enhanced, and producing long-chain fatty acids or the lipids containing these fatty acids as components, wherein: protein (A) is a protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and protein (B) is a protein consisting of an amino acid sequence having 70% or more identity with the amino acid sequence of the protein (A), and having ?-ketoacyl-ACP synthase activity.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: July 2, 2019
    Assignee: Kao Corporation
    Inventors: Tatsuro Ozaki, Shinji Sugihara
  • Publication number: 20190071698
    Abstract: A method of producing lipids, containing the steps of: culturing a transformant wherein the expressions of a gene encoding any one of the following proteins (A) to (F) and a gene encoding an acyl-ACP thioesterase are enhanced, and producing fatty acids or lipids containing these fatty acids as components: (A) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 2; (B) a protein consisting of an amino acid sequence having 89% or more identity with the amino acid sequence of the protein (A), and having acyl-CoA synthetase activity; (C) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 4; (D) a protein consisting of an amino acid sequence having 49% or more identity with the amino acid sequence of the protein (C), and having acyl-CoA synthetase activity; (E) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 6; and (F) a protein consisting of an amino acid sequence having 85% or more identity with the amino acid sequence of the protein (E), a
    Type: Application
    Filed: March 31, 2017
    Publication date: March 7, 2019
    Applicant: Kao Corporation
    Inventor: Shinji SUGIHARA
  • Publication number: 20190010525
    Abstract: A method of producing lipids, containing the steps of: culturing a transformant in which the expression of a gene encoding the following protein (A) or (B) is enhanced, and producing long-chain fatty acids or the lipids containing these fatty acids as components, wherein: protein (A) is a protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and protein (B) is a protein consisting of an amino acid sequence having 70% or more identity with the amino acid sequence of the protein (A), and having ?-ketoacyl-ACP synthase activity.
    Type: Application
    Filed: August 2, 2016
    Publication date: January 10, 2019
    Applicant: KAO CORPORATION
    Inventors: Tatsuro OZAKI, Shinji SUGIHARA
  • Publication number: 20180371127
    Abstract: [Object] To provide a method for producing a vinyl ether polymer having a hydroxyl group on the side chain, wherein the vinyl ether polymer having a low viscosity and excellent workability and processability is produced in a simple and efficient method. [Means for solving problem] The present invention relates to a method for producing a vinyl ether polymer having a hydroxyl group on the side chain, characterized in that vinyl ether comprising a hydroxyl group is subjected to radical polymerization by using an oil-soluble azo polymerization initiator, in the presence of a mixed solvent comprising water and an organic solvent selected from alcohol or cyclic ether radical polymerization.
    Type: Application
    Filed: December 14, 2016
    Publication date: December 27, 2018
    Applicant: MARUZEN PETROCHEMICAL CO., LTD.
    Inventors: Norihiro YOSHIDA, Shinji SUGIHARA
  • Patent number: 10066248
    Abstract: The present disclosure provides a gene encoding a protein having ?-ketoacyl-ACP synthase activity having at least 60% or more identity with the amino acid sequence set forth in SEQ ID NO:1, the protein encoded by the gene, a method of producing a transformant by transforming a host with the gene, a transformant that is transformed with the gene, and a method of producing a lipid, especially, a lipid containing a medium chain fatty acid or ester thereof, by culturing the transformed host that expresses the gene. In some embodiments, the transformant also has a gene encoding an acyl-ACP thioesterase.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: September 4, 2018
    Assignee: KAO CORPORATION
    Inventors: Shinji Sugihara, Tatsuro Ozaki, Hiroko Endo, Takeshi Saito, Takuto Tojo, Hiroyuki Ohta, Koichi Hori
  • Publication number: 20180245110
    Abstract: A method of producing lipids, containing the steps of: culturing a transformant in which the expression of a gene encoding the following protein (A) or (B) is enhanced, and producing fatty acids or lipids containing these fatty acids as components: (A) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and (B) a protein consisting of an amino acid sequence having 44% or more identity with the amino acid sequence of the protein (A), and having acyltransferase activity.
    Type: Application
    Filed: September 1, 2016
    Publication date: August 30, 2018
    Applicant: Kao Corporation
    Inventor: Shinji SUGIHARA
  • Publication number: 20180223299
    Abstract: A method of improving lipid productivity, containing the steps of: enhancing the expression of a gene encoding the following protein (A) or (B), and improving the productivity of medium-chain fatty acids or lipids containing these fatty acids as components produced in a cell of a transformant, or the total amount of all fatty acids produced in a cell of a transformant: (A) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and (B) a protein consisting of an amino acid sequence having 64% or more identity with the amino acid sequence of the protein (A), and having glycerol-3-phosphate dehydrogenase activity.
    Type: Application
    Filed: September 1, 2016
    Publication date: August 9, 2018
    Applicant: KAO CORPORATION
    Inventor: Shinji Sugihara
  • Publication number: 20180179305
    Abstract: A method for producing a hydroxyl group-containing vinyl ether polymer according to the present invention includes: a step of radical polymerizing at least one vinyl ether selected from vinyl ether having a hydroxyl group represented by the following formula (2): wherein R7 represents an alkylene group which is straight-chained, branched or comprises an alicyclic structure, and p is 1, 2, or 3, in the presence of water as a polymerization solvent and an azo compound represented by the following formula (1) as a polymerization initiator: wherein R1 to R4 each independently represent a hydrogen atom or an alkyl group and R5 and R6 each independently represent an alkoxy group optionally having a substituent group or an alkyl amino group optionally having a substituent group.
    Type: Application
    Filed: June 29, 2016
    Publication date: June 28, 2018
    Applicant: MARUZEN PETROCHEMICAL CO., LTD.
    Inventors: Shinji SUGIHARA, Norihiro YOSHIDA
  • Publication number: 20180155477
    Abstract: An alkenyl ether-vinyl ester copolymer contains a repeating unit derived from a hydroxyl group-containing alkenyl ether represented by the following formula (1), and a repeating unit derived from a vinyl ester represented by the following formula (2): where R1, R2 and R3 each independently represents a hydrogen atom or an alkyl group having from 1 to 4 carbon atoms, R4 represents a linear or branched alkylene group having from 2 to 4 carbon atoms; R5 represents an acyl group having from 1 to 20 carbon atoms; and p represents an integer of from 1 to 3. The alkenyl ether-vinyl ester copolymer exhibits temperature responsiveness showing a change in hydrophilicity and hydrophobicity at a prescribed temperature as a critical point and has a lower critical solution temperature to water of from 1° C. to 99° C.
    Type: Application
    Filed: May 2, 2016
    Publication date: June 7, 2018
    Applicant: Maruzen Petrochemical Co., Ltd.
    Inventor: Shinji SUGIHARA
  • Publication number: 20180135084
    Abstract: A method of producing a lipid, containing the steps of: culturing a transformant obtained by introducing a gene encoding the following protein (a) or (b) into cyanobacteria, and producing a lipid: (a) a protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and (b) a protein consisting of an amino acid sequence having 60% or more identity with the amino acid sequence of the protein (a), and having ?-ketoacyl-ACP synthase activity.
    Type: Application
    Filed: May 20, 2016
    Publication date: May 17, 2018
    Applicant: Kao Corporation
    Inventors: Akihito KAWAHARA, Shinji SUGIHARA
  • Publication number: 20180118869
    Abstract: To provide a method for producing a polymer that is capable of providing an alkenyl ether polymer having a molecular weight, a molecular weight distribution, and a composition that are controlled, with a vinyl ether having a hydroxyl group, and a block copolymer thereof. To provide a polymer obtained by the method as a macro chain transfer agent capable of performing reversible addition fragmentation chain transfer polymerization. Livingness can be imparted to radical polymerization of a hydroxyl group-containing vinyl ether by performing the radical polymerization in the presence of a particular RAFT agent and a radical polymerization initiator, and a block copolymer with another radically polymerizable vinyl monomer can be obtained by using the resulting living polymer as a macro chain transfer agent capable of performing reversible addition fragmentation chain transfer polymerization.
    Type: Application
    Filed: May 2, 2016
    Publication date: May 3, 2018
    Applicant: Maruzen Petrochemical Co., Ltd.
    Inventor: Shinji SUGIHARA
  • Patent number: 9777085
    Abstract: A method of producing a homopolymer or random copolymer of hydroxyl group-containing vinyl ether by polymerizing a monomer component comprising at least one hydroxyl group-containing vinyl ether using an oil-soluble radical polymerization initiator in the absence or presence of a solvent.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: October 3, 2017
    Assignee: Maruzen Petrochemical Co., Ltd.
    Inventors: Shinji Sugihara, Tomohiro Masukawa
  • Publication number: 20170107545
    Abstract: [Problems] To provide a method of producing a medium chain fatty acid or a lipid containing this fatty acid as a component by using a ?-ketoacyl-ACP synthase, and a gene, a protein and a transformant for use in this method. [Means to solve] A method of producing a medium chain fatty acid or a lipid containing this fatty acid as a component, containing the steps of: introducing a gene encoding the following protein (A) or (B) into a host, and thereby obtaining a transformant, and collecting a medium chain fatty acid or a lipid containing this fatty acid as a component from the resulting transformant; and a gene, a protein and a transformant for use in this method: (A) A protein consisting of the amino acid sequence set forth in SEQ ID NO: 1; and (B) A protein consisting of an amino acid sequence having 90% or more identity with the amino acid sequence set forth in SEQ ID NO: 1, and having medium chain acyl-ACP-specific ?-ketoacyl-ACP synthase activity.
    Type: Application
    Filed: July 30, 2015
    Publication date: April 20, 2017
    Applicant: Kao Corporation
    Inventors: Takuto TOJO, Shinji SUGIHARA
  • Publication number: 20170044580
    Abstract: A method of producing a lipid, containing the following steps (1) and (2); and a transformant obtained by introducing a gene encoding the following protein (a) or (b) into a host: (1) introducing a gene encoding the following protein (a) or (b) into a host, and thereby obtaining a transformant, and (2) collecting a lipid from the resulting transformant: (a) A protein consisting of an amino acid sequence set forth in SEQ ID NO: 1; and (b) A protein consisting of an amino acid sequence having 60% or more identity with the amino acid sequence of the protein (a), and having ?-ketoacyl-ACP synthase activity.
    Type: Application
    Filed: February 23, 2015
    Publication date: February 16, 2017
    Applicant: Kao Corporation
    Inventors: Shinji SUGIHARA, Tatsuro OZAKI, Hiroko ENDO, Takeshi SAITO, Takuto TOJO, Hiroyuki OHTA, Koichi HORI
  • Patent number: 9547315
    Abstract: An internal pressure sensor detects an internal pressure of the fuel tank, which stores fuel. A solenoid valve is configured to close to seal the fuel tank and is configured to open to open the fuel tank. An internal pressure acquisition unit is configured to acquire an internal pressure of the fuel tank from the internal pressure sensor. A drive control unit is configured to control the solenoid valve to open when the internal pressure of the fuel tank is greater than or equal to a first predetermined value, which is a negative value, and is less than a second predetermined value, which is 0 or a positive value.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: January 17, 2017
    Assignee: DENSO CORPORATION
    Inventors: Yuichiro Miura, Shinji Sugihara