Patents by Inventor Takashi Miki
Takashi Miki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8868146Abstract: A re-condensation device allows an NMR analysis device to be reduced in overall size and minimizes heat penetration into a liquid helium tank. An NMR analysis device provided with said re-condensation device. The re-condensation device includes: a second cooling member, part of which is inserted into a neck tube, and which re-condenses liquid helium; and a first cooling member, part of which is inserted into the neck tube. The second cooling member is thermally connected to a chiller's second cooling stage, and the first cooling member is thermally connected to the chiller's first cooling stage. The first cooling member has: a first insertion part, which has a diameter that allows insertion into the neck tube; and an inside contact part on the outer surface of the first insertion part and that cools heat seals by contacting, from the inside, a part of the neck tube that outside contact parts contact.Type: GrantFiled: March 25, 2011Date of Patent: October 21, 2014Assignee: Kobe Steel Ltd.Inventor: Takashi Miki
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Patent number: 8834691Abstract: The objective of the invention is to enhance measurement accuracy in a device for measuring a biological sample. To attain this objective, the invention is provided with a main case (2) having a sensor insertion section (1), a measurement section (7) connected to the sensor insertion section (1), a controller (8) connected to the measurement section (7), and a display (3) connected to the controller (8). An acceleration sensor (5) is furnished for detecting a shock applied to the sensor insertion section (1).Type: GrantFiled: March 28, 2012Date of Patent: September 16, 2014Assignee: Panasonic Healthcare Co., Ltd.Inventors: Reiko Kondo, Takashi Miki, Atsushi Watanabe
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Patent number: 8785651Abstract: The present invention relates to a method for manufacturing a boronic acid ester compound, characterized by reacting an aryl halide compound and a diboron ester compound in the presence of a nitrogen-containing organic base, a nickel catalyst, a phosphine compound and a solvent. According to the manufacturing method of the present invention, even if a nickel catalyst is used as the catalyst, a desired boronic acid ester compound can be obtained in a sufficiently high yield. Furthermore, even if aryl chloride or aryl bromide having relatively low price and low reactivity, was used as the aryl halide compound, a desired boronic acid ester compound can be obtained in a sufficiently high yield.Type: GrantFiled: March 24, 2009Date of Patent: July 22, 2014Assignees: Sumitomo Chemical Company, Limited, Genentech, Inc.Inventors: Takashi Miki, Yasuharu Shimasaki, Srinivasan Babu, Zhigang Cheng, Mark E. Reynolds, Qingping Tian
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Patent number: 8726786Abstract: A stack valve 1 includes an ascending dividing valve 14 which is provide on an ascending junction path 23 and controls the flow rate of a pressure fluid supplied to a head-side chamber 4a of a bucket cylinder 4, an ascending branched path 24 which is branched from the ascending junction path 23 and connected to an unloading path 21, and an ascending cancellation switching valve 19 which is provided on the ascending branched path 24 to close or open the ascending branched path 24. The ascending dividing valve 14 and the ascending cancellation switching valve 19 are provide in the same dividing section 83.Type: GrantFiled: June 12, 2009Date of Patent: May 20, 2014Assignee: Nabtesco CorporationInventors: Takashi Miki, Yasunori Hatanaka
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Patent number: 8690493Abstract: An end mill including multiple spiral flutes in a helical shape around an axis that are formed in a periphery of the top portion of an end mill body which rotates on the axis. Cutting edges are formed at peripheral side ridge portions of wall surfaces of the flutes facing a front side in an end mill rotating direction. Honing is applied along each peripheral cutting edge such that the cutting edge has a variable honing width in the direction of the axis.Type: GrantFiled: August 12, 2008Date of Patent: April 8, 2014Assignee: Mitsubishiki Materials CorporationInventors: Takashi Miki, Yuji Takagi
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Patent number: 8669395Abstract: Provided is a new crystal A of optically active 4-amino-3-(4-chlorophenyl)butanoic acid which is far better in stability, and a process for producing the crystal and a process for producing the crystal A comprising a step of heating the following crystal B in water having a pH of 3 to 9: crystal A: a crystal of optically active 4-amino-3-(4-chlorophenyl)butanoic acid which has diffraction peaks within the range of a diffraction angle 2? of 8.7 to 9.4°, within that of 2? of 12.2 to 12.8°, and within that of 2? of 24.8 to 25.4° in a powder X-ray diffraction measurement of the crystal by use of the Cu—K? wavelength; and crystal B: a crystal of optically active 4-amino-3-(4-chlorophenyl)butanoic acid which has diffraction peaks within the range of a diffraction angle 2? of 20.8 to 21.4°, within that of 2? of 26.7 to 27.3°, and within that of 2? of 29.7 to 30.3° in a powder X-ray diffraction measurement of the crystal by use of the Cu—K? wavelength.Type: GrantFiled: December 13, 2010Date of Patent: March 11, 2014Assignee: Sumitomo Chemical Company, LimitedInventors: Takashi Miki, Masahiro Takeda, Tetsuro Yamazaki
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Publication number: 20130334041Abstract: The objective of the invention is to enhance measurement accuracy in a device for measuring a biological sample. To attain this objective, the invention is provided with a main case (2) having a sensor insertion section (1), a measurement section (7) connected to the sensor insertion section (1), a controller (8) connected to the measurement section (7), and a display (3) connected to the controller (8). An acceleration sensor (5) is furnished for detecting a shock applied to the sensor insertion section (1).Type: ApplicationFiled: March 28, 2012Publication date: December 19, 2013Applicant: PANASONIC CORPORATIONInventors: Reiko Kondo, Takashi Miki, Atsushi Watanabe
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Patent number: 8607821Abstract: A stack valve 1 includes a boom direction switching valve 11 (first direction switching valve) connected to an unloading path 21 and a service valve 13 (second direction switching valve) connected to the unloading path 21 at the downstream of the boom direction switching valve 11. At changeover positions 11a and 11c at which the unloading path 21 on the upstream side is connected to one of the supply and discharge paths 29 and 30 and the other one of the supply and discharge paths 29 and 30 is connected to the unloading path 21 on the downstream side, the boom direction switching valve 11 is connected to a boom valve tank return path 27 which connects the other one of the supply and discharge paths 29 and 30 with the tank path 22.Type: GrantFiled: March 15, 2011Date of Patent: December 17, 2013Assignee: Nabtesco CorporationInventor: Takashi Miki
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Publication number: 20130266482Abstract: This biological sample measuring device comprises a mounting portion (4) to which a biological sample measuring sensor (3) is mounted, a voltage application section (12) that applies voltage to a counter electrode (8) of the biological sample measuring sensor (3) mounted to the mounting portion (4), amplifiers (14 and 15) that are selectively connected to a working electrode (9) of the biological sample measuring sensor (3), and a determination section (19) that is connected to these amplifiers (14 and 15).Type: ApplicationFiled: January 16, 2012Publication date: October 10, 2013Inventors: Shouko Hironaka, Teppei Shinno, Eriko Yoshioka, Takashi Miki
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Publication number: 20130123110Abstract: A re-condensation device allows an NMR analysis device to be reduced in overall size and minimizes heat penetration into a liquid helium tank. An NMR analysis device provided with said re-condensation device. The re-condensation device includes: a second cooling member, part of which is inserted into a neck tube, and which re-condenses liquid helium; and a first cooling member, part of which is inserted into the neck tube. The second cooling member is thermally connected to a chiller's second cooling stage, and the first cooling member is thermally connected to the chiller's first cooling stage. The first cooling member has: a first insertion part, which has a diameter that allows insertion into the neck tube; and an inside contact part on the outer surface of the first insertion part and that cools heat seals by contacting, from the inside, a part of the neck tube that outside contact parts contact.Type: ApplicationFiled: March 25, 2011Publication date: May 16, 2013Applicant: Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd.)Inventor: Takashi Miki
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Patent number: 8415140Abstract: An analysis device includes: a separation cavity 18 for separating a test liquid into a solution component and a solid component by using a centrifugal force; a higher specific gravity component quantitative cavity 23 for holding a portion of the separated solid component which has been transferred; a sample solution overflow cavity 22 arranged between the higher specific gravity component quantitative cavity 23 and the separation cavity 18 and connected to a connecting channel 21 for transporting the sample liquid from the separation cavity 18; and a capillary cavity 19 formed in the separation cavity 18 for temporarily holding a separated solution component (blood plasma) in the separation cavity 18. A blood plasma component 57a remaining in the separation cavity 18 is trapped by the capillary cavity 19.Type: GrantFiled: October 3, 2008Date of Patent: April 9, 2013Assignee: Panasonic CorporationInventors: Hiroshi Saiki, Takashi Miki, Takuya Suzuki
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Patent number: 8409831Abstract: The present invention provides a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid with a high yield and high selectivity. Specifically, disclosed is a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid, wherein (1S)-2-chloro-2-fluorocyclopropanecarboxylic acid ester is hydrolyzed using an esterase derived from Burkholderia cepacia.Type: GrantFiled: July 7, 2009Date of Patent: April 2, 2013Assignees: Sumitomo Chemical Company, Limited, Daiichi Sankyo Company, LimitedInventors: Keisuke Hatakeyama, Takashi Miki, Norihiko Hirata
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Publication number: 20130009645Abstract: A compact flow-through NMR analyzer with high NMR signal detection sensitivity is provided. The flow-through NMR analyzer comprises: a solution feeding pipe 18 for flowing a sample fed from a solution feeding pump 6; a superconducting magnet 7 that encloses a housing space, which is surrounded by a side wall of the solution feeding pipe 18, around an axis of the solution feeding pipe 18 such that a static magnetic field is generated along the axis of the solution feeding pipe 18; a vacuum container 12 which houses the superconducting magnet 7 in a cooled state and which encloses the housing space around the axis of the solution feeding pipe 18; and an RF coil 22 which applies high-frequency electromagnetic waves to the sample inside the housing space and which detects an NMR signal from the sample.Type: ApplicationFiled: March 25, 2011Publication date: January 10, 2013Applicant: KABUSHIKI KAISHA KOBE SEIKO SHO KOve Steel,. Ltd.)Inventor: Takashi Miki
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Publication number: 20130009643Abstract: A compact NMR analyzer for clinical examinations which is suitable for use at medical facilities is provided. An NMR analyzer for clinical examinations 1 for analyzing a sample including a liquid component extracted from a human body, includes: a solution feeding pump 6 that feeds a sample; a solution feeding pipe 18 that receives the sample fed from the solution feeding pump 6; a superconducting magnet 7 that encloses the solution feeding pipe 18 around an axis thereof; a helium container 9 that houses the superconducting magnet 7 and liquid helium 8; a vacuum container 12 that has a vacuum chamber and that houses the helium container 9 inside the vacuum chamber; heat shields 10 and 11 that cover the helium container 9 in the vacuum container 12; and a recondensing unit 3 that recondenses helium vaporized inside the helium container 9 and that cools the heat shields 10 and 11.Type: ApplicationFiled: March 25, 2011Publication date: January 10, 2013Inventors: Takashi Miki, Yasuaki Terao
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Patent number: 8204424Abstract: The present invention provides a cleaning blade for an electrophotographic device, which, even when spherical (perfectly spherical or irregularly shaped), polymerized toner with a small particle diameter is used, can achieve sufficient abrasion resistance and sufficient cleaning ability (particularly cleaning ability under low-temperature and low-humidity conditions). The cleaning blade for an electrophotographic device includes an elastic rubber member; and a supporting member. The elastic rubber member has a double layer structure including an edge layer and a base layer. The edge layer is made of a material with a JIS-A hardness of 65° to 72° at 23° C. and a rebound resilience of 10 to 35%. The base layer is made of a material with a JIS-A hardness of 70° to 80° at 23° C. and a rebound resilience of 40 to 70%, the JIS-A hardness value being larger than the value of hardness of the edge layer.Type: GrantFiled: November 8, 2007Date of Patent: June 19, 2012Assignee: Bando Chemical Industries, Ltd.Inventors: Takashi Miki, Takayuki Nagase, Sadaharu Nakamura
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Publication number: 20120148352Abstract: An end mill including multiple spiral flutes in a helical shape around an axis that are formed in a periphery of the top portion of an end mill body which rotates on the axis. Cutting edges are formed at peripheral side ridge portions of wall surfaces of the flutes facing a front side in an end mill rotating direction. Honing is applied along each peripheral cutting edge such that the cutting edge has a variable honing width in the direction of the axis.Type: ApplicationFiled: August 12, 2008Publication date: June 14, 2012Applicant: MITSUBISHI MATERIALS CORPORATIONInventors: Takashi Miki, Yuji Takagi
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Publication number: 20120123122Abstract: The present invention relates to a method for manufacturing a boronic acid ester compound, characterized by reacting an aryl halide compound and a diboron ester compound in the presence of a nitrogen-containing organic base, a nickel catalyst, a phosphine compound and a solvent. According to the manufacturing method of the present invention, even if a nickel catalyst is used as the catalyst, a desired boronic acid ester compound can be obtained in a sufficiently high yield. Furthermore, even if aryl chloride or aryl bromide having relatively low price and low reactivity, was used as the aryl halide compound, a desired boronic acid ester compound can be obtained in a sufficiently high yield.Type: ApplicationFiled: March 24, 2009Publication date: May 17, 2012Applicants: GENENTECH, INC., SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Takashi Miki, Yasuharu Shimasaki, Srinivasan Babu, Zhigang Cheng, Mark E. Reynolds, Qingping Tian
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Publication number: 20120065426Abstract: The present invention aims to provide a practical process for preparing amine compounds through a generalized highly-diastereoselective reductive amination reaction.Type: ApplicationFiled: September 14, 2011Publication date: March 15, 2012Applicant: Kanto Kagaku Kabushiki KaishaInventors: Masahito Watanabe, Kouichi Tanaka, Takashi Miki, Kunihiko Murata
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Publication number: 20110232787Abstract: A stack valve 1 includes a boom direction switching valve 11 (first direction switching valve) connected to an unloading path 21 and a service valve 13 (second direction switching valve) connected to the unloading path 21 at the downstream of the boom direction switching valve 11. At changeover positions 11a and 11c at which the unloading path 21 on the upstream side is connected to one of the supply and discharge paths 29 and 30 and the other one of the supply and discharge paths 29 and 30 is connected to the unloading path 21 on the downstream side, the boom direction switching valve 11 is connected to a boom valve tank return path 27 which connects the other one of the supply and discharge paths 29 and 30 with the tank path 22.Type: ApplicationFiled: March 15, 2011Publication date: September 29, 2011Applicant: NABTESCO CORPORATIONInventor: Takashi Miki
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Patent number: 7990148Abstract: An object of the present invention is to provide a cooled NMR probe including an antenna coil and capable of decreasing an operation temperature of the antenna coil by effectively cooling the antenna coil, thereby increasing detection sensitivity of an NMR signal. To attain this, a probe head according to the present invention includes a coil support member which supports the antenna coil, and a cooling member arranged around at least a portion of the coil support member, the cooling member providing a cooling space between the cooling member and the coil support member, the cooling space allowing a refrigerant to circulate therethrough. The cooling member is coupled to the coil support member such that the refrigerant flowing in the cooling space directly contacts an outer peripheral surface of the coil support member.Type: GrantFiled: August 10, 2007Date of Patent: August 2, 2011Assignee: Kobe Steel Ltd.Inventor: Takashi Miki