Abstract: The invention relates to a protective helmet with an outer shell (1) for distributing impact forces, an interior layer (2) accommodated by the outer shell (1) for attenuating impact forces, and a slot (3) for accommodating an electrical device (4), wherein the outer shell (1) has a chin shell area (6) to cover a chin portion of a protective helmet wearer, wherein the outer shell (1) forms a viewing port (8) for the protective helmet wearer to look through. The protective helmet is characterized in that the slot (3) is arranged on the chin shell area (6) in such a way that the accommodated electrical device (4) is arranged between the chin shell area (6) and the interior layer (2), wherein the protective helmet has an interior cover (10) for essentially completely covering the accommodated electrical device (4) in the direction of the viewing port (8).

Abstract: The present invention relates to a formulation comprising a polyether siloxane, which is characterized in that a polyether that is terminated with an ester group and that is different from the polyether siloxane is present in the formulation in an amount of from 0.5 to 10% by weight based on the complete formulation, to a process for the production of a defoamed composition, wherein the inventive formulation is added to the composition to be defoamed, and to a composition comprising a formulation according to the invention, wherein the composition is a coating agent, a paint or a varnish.

Abstract: The invention pertains to the use of lonafarnib or any analog or derivative thereof for the treatment of a viral disease characterized by a viral entry into a host cell via a viral fusion glycoprotein (F-protein). In particular, the invention provides treatments of human respiratory syncytial virus (HRSV) caused diseases comprising the administration (use) of lonafarnib or its analogs or derivatives, as well as pharmaceutical compositions comprising lonafarnib or its analogs and derivates.

Abstract: Determination device (2) for determining at least one parameter of an energy beam (4), in particular an energy beam (4) generated via an irradiation device of an apparatus (1) for additively manufacturing three-dimensional objects, which determination device (2) comprises two determination units (5, 6) arrangeable or arranged in succession in a beam path (3) of the energy beam (4), characterized in that each determination unit (5, 6) builds or comprises at least one complementary pattern element (15, 18, 21, 23, 24, 27, 30), wherein at least two pattern elements (15, 18, 21, 23, 24, 27, 30) of the two determination units (5, 6) complement each other to a superordinate pattern (32, 35).

Abstract: Provided are compounds of Formula (I?): or pharmaceutically acceptable salts thereof, wherein the variables in the formula are as defined herein; and methods for their use and production.

Abstract: A framework section having a connection region which is formed on the end face of at least one of its two ends. The connection region can be connected to the connection region of a further framework section. The framework section can include two upper chord sections and two lower chord sections, which extend parallel to one another in the longitudinal direction of the framework section and are connected to one another by connecting struts such that they define a cuboid space. The upper chord sections and the lower chord sections can have a tubular cross section, wherein the upper chord sections and the lower chord sections can also be configured to transition from the tubular cross section into an I-shaped cross section in the connection region.

Abstract: Disclosed herein are cell culture compositions, for example, pancreatic cell culture compositions, derived from dedifferentiated human reprogrammed pluripotent stem cells, such as induced pluripotent stem (iPS) cells, and methods for producing and using such cell culture compositions.

Abstract: Determination device (2) for determining at least one parameter of an energy beam (4), in particular an energy beam (4) generated via an irradiation device of an apparatus (1) for additively manufacturing three-dimensional objects, which determination device (2) comprises two determination units (5, 6) arrangeable or arranged in succession in a beam path (3) of the energy beam (4), characterized in that each determination unit (5, 6) builds or comprises at least one complementary pattern element (15, 18, 21, 23, 24, 27, 30), wherein at least two pattern elements (15, 18, 21, 23, 24, 27, 30) of the two determination units (5, 6) complement each other to a superordinate pattern (32, 35).

Abstract: Apparatus for additively manufacturing three-dimensional objects by means of successive layerwise selective irradiation and consolidation of layers of a build material which can be consolidated by means of an energy beam, which apparatus comprises an irradiation device adapted to guide an energy beam across a build plane, wherein a calibration device is provided comprising a positioning unit, a determination unit and a calibration unit, preferably arranged in a process chamber of the apparatus, that is adapted to at least partially reflect the energy beam, wherein the irradiation device is adapted to guide the energy beam to the calibration unit for generating a reflected part of the energy beam, wherein the positioning unit is adapted to position the irradiation device dependent on at least one parameter of the reflected part of the energy beam determined via the determination unit.

Abstract: The present invention relates to novel labyrinthopeptin derivatives. These labyrinthopeptin derivatives are useful for the treatment of infectious diseases, such as an infectious disease caused by an infection with human respiratory syncytial virus (RSV), Kaposi sarcoma-associated herpesvirus (KSHV), cytomegalovirus (CMV/HCMV), dengue virus (DENV), chikungunya virus (CHIKV), tick-borne encephalitis virus (TBEV; FSME virus), vesicular stomatitis Indiana virus (VSV), zika virus (ZIKV) and/or hepatitis C virus (HCV). Said labyrinthopeptin derivatives are also useful for analyzing the mode of action of labyrinthopeptins. Also encompassed by the present invention are labyrinthopeptins for use in treating an infectious disease, in particular an infectious disease caused by an infection with any one of the viruses selected from RSV, KSHV, CMV, CHIKV, TBEV, VSV, ZIKV and HCV. The invention further relates to a combination of labyrinthopeptin A1 and A2 for use as a medicament, e.g.

Abstract: The invention relates to an implant with a shank which is insertible into a bone cavity, which shank is made of a plastic, in particular of a bioincompatible plastic, and defines at least one bone contact face, wherein the bone contact face is provided or coated with a first biocompatible bone contact layer or bears a biocompatible bone contact layer, wherein the shank of the implant is intended to be anchored in the bone cavity without bone cement and wherein the first bone contact layer is formed entirely closed.

Abstract: The invention relates to a protective helmet, in particular a protective motorcycle helmet, comprising an outer shell (1) for distributing impact forces, a battery socket (2), which is firmly connected to the outer shell (1), for detachably accommodating a battery (3), and a line assembly (4), which is electrically connected to the battery socket (2), for supplying electricity by means of the accommodated battery (3) to an electric apparatus (5) which is mechanically coupled to the outer shell (1).

Abstract: Disclosed herein are cell culture compositions, for example, pancreatic cell culture compositions, derived from dedifferentiated human reprogrammed pluripotent stem cells, such as induced pluripotent stem (iPS) cells, and methods for producing and using such cell culture compositions.

Abstract: A system, method, apparatus, and computer program product for configuring a network connected appliance to use online services are disclosed. A method may include receiving an indication of a selected home automation system for a network connected appliance. The selected home automation system may be selected from multiple available home automation systems. The method may additionally include registering the network connected appliance to the selected home automation system. The method may also include enabling communication between the network connected appliance and the selected home automation system.

Abstract: The invention relates to a protective helmet, and in particular a protective motorcycle helmet, comprising an outer shell (1) for distributing impact forces and a socket (2), which is firmly connected to the outer shell (1), for accommodating an electrical accessory (3), wherein the socket (2) is disposed on an edge (6) of the outer shell (1) and the socket (2) is configured, when accommodating the accessory (3), for guiding the latter substantially along an inner face (7) of the outer shell (1), so that the accommodated accessory (3) extends substantially along the inner face (7) of the outer shell (1).

Abstract: The invention relates to a protective helmet, and in particular, to a protective motorcycle helmet, comprising an antenna (1) for radio transmission, an outer shell (2) for distributing impact forces, an inner layer (3), which is accommodated by the outer shell (2), for damping impact forces, and a socket (4), which is firmly connected to the outer shell (2), for contacting a digital device (5) for wireless communication, wherein the socket (4), when contacting the digital device (5), electrically connects the latter to the antenna (1) for wireless communication. The protective helmet is characterized in that at least a partial layer of the outer shell (2) is disposed between the antenna (1) and the inner layer (3).

Abstract: The invention relates to a protective helmet with an outer shell (1) for distributing impact forces, an interior layer (2) accommodated by the outer shell (1) for attenuating impact forces, and a slot (3) for accommodating an electrical device (4), wherein the outer shell (1) has a chin shell area (6) to cover a chin portion of a protective helmet wearer, wherein the outer shell (1) forms a viewing port (8) for the protective helmet wearer to look through. The protective helmet is characterized in that the slot (3) is arranged on the chin shell area (6) in such a way that the accommodated electrical device (4) is arranged between the chin shell area (6) and the interior layer (2), wherein the protective helmet has an interior cover (10) for essentially completely covering the accommodated electrical device (4) in the direction of the viewing port (8).

Abstract: A cooking appliance for heating food comprises a remote control for controlling the cooking appliance remotely. According to the present invention a distance control is provided for detecting the distance between the remote control 10 or a user and the cooking appliance.

Abstract: The invention relates to an ultrahigh strength multiphase steel having a minimum tensile strength of 980 MPa containing (in wt. %): C?0.075 to ?0.115; Si?0.400 to ?0.500; Mn?1.900 to ?2.350; Cr?0.250 to ?0.400; Al?0.010 to ?0.060; N?0.0020 to ?0.0120; P?0.020; S?0.0020; Ti?0.005 to ?0.060; Nb?0.005 to ?0.060; V?0.005 to ?0.020; B?0.0005 to ?0.0010; Mo?0.200 to ?0.300; Ca?0.0010 to ?0.0060; Cu?0.050; Ni?0.050; Sn?0.040; H?0.0010; and residual iron, including customary steel-accompanying smelting-related impurities, wherein the total content of Mn+Si+Cr is ?1.750 to ?2.250 wt. % with a view to a processing window which is as wide as possible during the annealing process, in particular during the continuous annealing process, of cold strips of said steel.

Abstract: Apparatus for additively manufacturing three-dimensional objects by means of successive layerwise selective irradiation and consolidation of layers of a build material which can be consolidated by means of an energy beam, which apparatus comprises an irradiation device adapted to guide an energy beam across a build plane, wherein a calibration device is provided comprising a positioning unit, a determination unit and a calibration unit, preferably arranged in a process chamber of the apparatus, that is adapted to at least partially reflect the energy beam, wherein the irradiation device is adapted to guide the energy beam to the calibration unit for generating a reflected part of the energy beam, wherein the positioning unit is adapted to position the irradiation device dependent on at least one parameter of the reflected part of the energy beam determined via the determination unit.