Abstract: The present invention is based, in part, on the discovery of the human-specific regulatory control of cGAS and the structure of the active human cGAS-DNA complex, as well as compositions comprising the modified hcGAS polypeptide, hcGAS-DNA complex, hcGAS-DNA-ATP complex, and methods of screening for modulators of the structure, expression, and/or activity of such polypeptides and complexes.

Abstract: The disclosure discloses a remote exercise rehabilitation management system for people with chronic diseases, including a server terminal, a doctor terminal and a patient terminal. Multi-disease integration principles are built in the server. Multiple independent fitness assessment protocol and multiple exercise rehabilitation prescriptions suitable for patients with different chronic diseases are stored in the server. The patient terminal collects the patient information by a health and lifestyle questionnaire, and transmits the patient information to the server. The server will design a fitness assessment protocol according to the patient's health information, and sends the fitness assessment protocol to the patient terminal. The patient terminal is able to present the fitness assessment protocol and collect patient's feedback. According to the feedback and built-in principles, the server will design an exercise prescription suitable to patient's health conditions.

Abstract: An information classification processing method of a carbonate reservoir and an information data processing terminal. The method includes: determining rock types; determining reservoir types on the basis of different rock types; and in accordance with the determined reservoir and rock types, performing porosity and permeability intersection by utilizing measured data; fitting a curve to obtain a porosity-permeability relation formula; and calculating permeability by utilizing the formula. According to the present invention, complex carbonate reservoirs in the Middle East can be classified, and porosity-permeability relations are respectively established, thereby increasing interpretation accuracy of permeability. According to the present invention, the reservoir types and the rock types can be rapidly and systematically classified, and clear porosity-permeability relations are obtained, so that interpretation of the permeability in oil reservoir exploitation is more accurate.

Abstract: The disclosure provides a method and device for three-dimensional reconstruction, applied to the field of image processing. The method includes: obtaining a first depth map, which is photographed by a first photographic device, and obtaining a second depth map, which is photographed by a second photographic device; merging the first depth map with a first three-dimensional model according to a position of the first photographic device to obtain a second three-dimensional model; and merging the second depth map with the second three-dimensional model according to a position of the second photographic device to obtain a third three-dimensional model.

Abstract: A gas-liquid separation device comprises: an outer housing extending vertically, which is provided with a gas outlet at an upper end of the outer housing and a liquid outlet at a lower end of the outer housing; an inner housing disposed in the outer housing and extending vertically, an upper end of the inner housing being coupled to the outer housing in a sealed manner, a lower end of the inner housing being opened, with an annular space formed between the outer housing and the inner housing; a feeding tube inserted into the outer housing and communicated with the inner housing, with a cyclone mechanism between the feeding tube and the inner housing to output fluid into the inner housing as a swirling flow. The present disclosure can reduce the disturbance of the downward gas flow and the upward gas flow in the separation space, thus improving the separation efficiency.

Abstract: A device for measuring a reflectivity of an object at the seabottom, includes a spectral probe, a first white board, a second white board, a distance meter, and a shaft; the first white board and the second white board respectively have a known reflectivity; the first white board and the second white board are connected to the shaft, wherein the first white board and the second white board are spaced along an axial direction of the shaft and staggered from each other along a radial direction of the shaft; the spectral probe is configured to collect spectral data of the first white board, the second white board and the object at the seabottom; the distance meter is configured to collect distance data between the spectral probe and the object at the seabottom.

Abstract: The disclosure relates to a low toxic tripterygium neoglycosides, which is obtained by chemically processing tripterygium glycosides and adding triptriolide. The disclosure also discloses the application of the low toxic tripterygium neoglycosides. The tripterygium neoglycosides can effectively relieve renal pathological injury and urinary protein of nephrotic syndrome, attenuate the inflammatory level of the body, have obvious treatment effect on nephrotic syndrome, and have low toxicity and persistent effect.

Abstract: The disclosure provides platinum(IV) prodrug perfluoroaryl peptide conjugates that can be used to treat cell proliferative disorders, such as those associated with malignant tumor cells. The conjugates can improve the delivery of platinum(IV) prodrugs to glioma cells.

Abstract: The disclosure provides a method and device for three-dimensional reconstruction, applied to the field of image processing. The method includes: obtaining a first depth map, which is photographed by a first photographic device, and obtaining a second depth map, which is photographed by a second photographic device; merging the first depth map with a first three-dimensional model according to a position of the first photographic device to obtain a second three-dimensional model; and merging the second depth map with the second three-dimensional model according to a position of the second photographic device to obtain a third three-dimensional model.

Abstract: A circuit board testing device electrically coupled to a measurement gauge tests a circuit board. The circuit board testing device includes a processor configured to configure measurement parameters of the measurement gauge, configure measurement rules for testing the circuit board, confirm a circuit of the circuit board to be tested according to the record of test data, control the measurement gauge to test the circuit of the circuit board to be tested when the measurement gauge is electrically coupled to the circuit of the circuit board to be tested, receive measurement data returned by the measurement gauge, and analyze a faulty region of the circuit board according to the record of test data and the measurement data.

Abstract: The present invention provides a method and a device for three-dimensional modeling, used in the field of image processing. The method includes: receiving a first two-dimensional image and a depth map corresponding to the first two-dimensional image; the first two-dimensional image and the depth map respectively include a face; fitting three-dimensional face model by a first three-dimensional face database according to a position of a face feature point in the first two-dimensional image and the depth map corresponding to the first two-dimensional image. The method and the device for three-dimensional modeling provided by the present invention can improve the efficiency of the facial three-dimensional modeling and the precision of modeling.

Abstract: The present invention provides a method and device for three-dimensional reconstruction, applied to the field of image processing. The method comprises: obtaining a first depth map, which is photographed by a first photographic device, and obtaining a second depth map, which is photographed by a second photographic device; merging the first depth map with a first three-dimensional model according to a position of the first photographic device to obtain a second three-dimensional model; and merging the second depth map with the second three-dimensional model according to a position of the second photographic device to obtain a third three-dimensional model. By adoption of the method, during the reconstruction of three-dimensional images, the reconstruction effect of the three-dimensional images of the top and the bottom of the target object can be improved, and the precision of the reconstructed three-dimensional images is improved.

Abstract: An apparatus and a method for removing nitrogen and phosphorus from sewage by using sponge iron and activated sludge are disclosed herein. The apparatus comprises a raw tank, a pH adjusting tank, a primary SBR reactor, a secondary SBR reactor, an intermediate tank, and a discharge tank; by modification of sponge iron, preparation of composite filler, sludge inoculation and domestication, and sewage treatment, an effect of simultaneous denitrification and dephosphorization is achieved in one reactor using the combined action of sponge iron and activated sludge with high nitrogen and phosphorus removal efficiency.

Abstract: The present invention provides a method and device for calibration, applied to the field of image processing. The method comprises: obtaining a first two-dimensional image of a calibration object with a marking point and a first depth map of the calibration object, obtaining calibrated three-dimensional model data of the calibration object, determining a first three-dimensional marking point in the first depth map corresponding to the marking point based on the marking point in the first two-dimensional image, determining a second three-dimensional marking point in the three-dimensional model data of the calibration object corresponding to the marking point based on the marking point in the first two-dimensional image, and determining a first matrix. By adoption of the method mentioned above, when the device for photographing the three-dimensional image is calibrated, it is simple and feasible, and the operation difficulty is small.

Abstract: On embodiment of the invention provides an optical lens includes a lens barrel, a first lens group and a photo interrupter disposed in the lens barrel, a light-shading sheet and a power machine. The photo interrupter has an optical transmitter and an optical receiver, the optical transmitter emits a light beam in a first direction, and the optical receiver receives the light beam. The light-shading sheet is disposed in a propagation path of the light beam and has two shading parts with mutually different lengths. The power machine is linked to a kinetic machine part, and the kinetic machine part is connected to the first lens group.

Abstract: Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV).

Abstract: A computer implemented method, computer system and computer program product are provided for lost detection for paired mobile devices. According to the method, a processor receives behavior data of paired mobile devices from one or more sensors of the paired mobile devices, wherein the behavior data comprising one or more parameters that reflect current status of the paired mobile devices. And the processor compares the received behavior data with human behavior data model. And, in response to the received behavior data being not matched with the human behavior data model, the processor determines that at least one of the paired mobile devices is lost.

Abstract: An apparatus and a method for removing nitrogen and phosphorus from sewage by using sponge iron and activated sludge are disclosed herein. The apparatus comprises a raw tank, a pH adjusting tank, a primary SBBR reactor, a secondary SBBR reactor, an intermediate tank, and a discharge tank; by modification of sponge iron, preparation of composite filler, sludge inoculation and domestication, and sewage treatment, an effect of simultaneous denitrification and dephosphorization is achieved in one reactor using the combined action of sponge iron and activated sludge with high nitrogen and phosphorus removal efficiency.

Abstract: A circuit board testing device electrically coupled to a measurement gauge tests a circuit board. The circuit board testing device includes a processor configured to configure measurement parameters of the measurement gauge, configure measurement rules for testing the circuit board, confirm a circuit of the circuit board to be tested according to the record of test data, control the measurement gauge to test the circuit of the circuit board to be tested when the measurement gauge is electrically coupled to the circuit of the circuit board to be tested, receive measurement data returned by the measurement gauge, and analyze a faulty region of the circuit board according to the record of test data and the measurement data.

Abstract: The disclosure relates to a low toxic tripterygium neoglycosides, which is obtained by chemically processing tripterygium glycosides and adding triptriolide. The disclosure also discloses the application of the low toxic tripterygium neoglycosides. The tripterygium neoglycosides can effectively relieve renal pathological injury and urinary protein of nephrotic syndrome, attenuate the inflammatory level of the body, have obvious treatment effect on nephrotic syndrome, and have low toxicity and persistent effect.