Abstract: A device including an image capturing device and a measuring device for determining the distance of at least one eye of a user from the image capturing device. The measuring device comprises a lighting device that is arranged at a specified position relative to the image capturing device and is designed to generate at least one specular light reflection, which has a linear portion, on the cornea of the eye of the user. The measuring device also comprises a distance determining device. The image capturing device is designed to capture at least one image of the specular light reflection in the region of the cornea of the at least one eye of the user.

Abstract: A pyrotechnical igniter (100) for an inflator of a vehicle safety system comprises at least two contact pins (102) physically separated from each other by an electrically insulating compound and a bridge wire (110) connected to both contact pins (102) in an electrically conducting manner. A fastening portion (112) in which the bridge wire (110) is welded to the contact pins (102) is provided at each of the contact pins (102).

Abstract: The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. Formula (I), wherein A represents O or N(R1); Y represents a group of formula, or wherein the left bond is attached to the A group and the right bond is attached to the R group; R represents a substituted or unsubstituted C5-C10aryl, substituted or unsubstituted hetero-C5-C10aryl, a group N(R1)(R4), or a group N(R2)(CHP3R4); R represent a hydrogen, C1-C4alkyl, or CF3; R2 represents hydrogen, C1-C4alkyl, or CF3; R3 represents hydrogen, C1-C4alkyl, or CF3; R4 represents a substituted or unsubstituted C5-C10 aryl or a substituted or unsubstituted C5-C10heteroaryl; in free base or acid addition salt form.

Abstract: A pyrotechnical igniter (100) for an inflator of a vehicle safety system comprises at least two contact pins (102) physically separated from each other by an electrically insulating compound and a bridge wire (110) connected to both contact pins (102) in an electrically conducting manner. A fastening portion (112) in which the bridge wire (110) is welded to the contact pins (102) is provided at each of the contact pins (102).

Abstract: A pyrotechnical igniter (100) for an inflator of a vehicle safety system comprises at least two contact pins (102) physically separated from each other by an electrically insulating compound and a bridge wire (110) connected to both contact pins (102) in an electrically conducting manner. A fastening portion (112) in which the bridge wire (110) is welded to the contact pins (102) is provided at each of the contact pins (102).

Abstract: A gearbox arrangement (1), which is arranged in a drive train of a multi-axle land vehicle (2), in particular a commercial vehicle, or a similar means of transportation, wherein at least one of said axles is driven, wherein at least one planetary drive (8) is associated with each of the axle halves (5) of a driven axle. The gearbox arrangement comprises at least one sensor device (7) for detecting a steering manipulation on the vehicle (2) and a control device (6).

Abstract: The invention relates to a pyrotechnic actuator assembly (10) for release of a retaining means (12) in a vehicle safety system (14) comprising a housing (16) composed of a first housing part (18) and a second housing part (20) fixedly connected to the first housing part (18), the two housing parts (18, 20) forming a substantially tight housing chamber (22), a pyrotechnic charge (24) received in the housing chamber (22) as well as an electric ignition unit (26) for triggering of the pyrotechnic charge (24), wherein the electric ignition unit (26) extends from outside of the housing chamber (22) through the first housing part (18) into the housing chamber (22), and wherein the housing (16) includes a housing chamber portion (28) to which the pyrotechnic charge (24) is directly adjacent and includes a contact portion (30) for fastening the retaining means (12). Moreover the invention also comprises an airbag module of a vehicle safety system including such actuator assembly (10).

Abstract: The present invention relates to 1-aza-bicy-cloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. Formula (I), wherein A represents O or N(R?); Y represents a group of formula, or wherein the left bond is attached to the A group and the right bond is attached to the R group; R represents a substituted or unsubstituted C5-C10aryl, substituted or unsubstituted hetero-C5-C10aryl, a group N(R1)(R4), or a group N(R2)(CHP3R4); R represent a hydrogen, C1-C4alkyl, or CF3; R2 represents hydrogen, C1-C4alkyl, or CF3; R3 represents hydrogen, C1-C4alkyl, or CF3; R4 represents a substituted or unsubstituted C5-C10 aryl or a substituted or unsubstituted C5-C10heteroaryl; in free base or acid addition salt form.

Abstract: The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. Formula (I), wherein A represents O or N(R1); Y represents a group of formula, or wherein the left bond is attached to the A group and the right bond is attached to the R group; R represents a substituted or unsubstituted C5-C10aryl, substituted or unsubstituted hetero-C5-C10aryl, a group N(R1)(R4), or a group N(R2)(CHP3R4); R represent a hydrogen, C1-C4alkyl, or CF3; R2 represents hydrogen, C1-C4alkyl, or CF3; R3 represents hydrogen, C1-C4alkyl, or CF3; R4 represents a substituted or unsubstituted C5-C10 aryl or a substituted or unsubstituted C5-C10heteroaryl; in free base or acid addition salt form.

Abstract: Disclosed is a rotor (1) for an electric rotor motor, consisting of a rotor bell (2) with a peripheral wall (4) and at least one one-sided rotor base (6) to enclose a stator, in particular as a part of a motor housing with a high IP rating, for example IP54 per DIN/IEC-EN 60034-5. The rotor bell (2) features a heat sink (12) with high heat conductivity that extends through the rotor base (6) in such a way that the motor heat arising on the inside can be removed via the heat sink (12) through the rotor base (6) to the outside into the environment. Further, the invention relates to an electric rotor motor, in particular with an encapsulated motor housing with a high IP-protection system, for example IP54 per DIN/IEC-EN 60034-5, consisting of a stator and a rotor (1) enclosing the stator in an embodiment of the above-described type.

Abstract: The invention relates to a pyrotechnic actuator assembly (10) for release of a retaining means (12) in a vehicle safety system (14) comprising a housing (16) composed of a first housing part (18) and a second housing part (20) fixedly connected to the first housing part (18), the two housing parts (18, 20) forming a substantially tight housing chamber (22), a pyrotechnic charge (24) received in the housing chamber (22) as well as an electric ignition unit (26) for triggering of the pyrotechnic charge (24), wherein the electric ignition unit (26) extends from outside of the housing chamber (22) through the first housing part (18) into the housing chamber (22), and wherein the housing (16) includes a housing chamber portion (28) to which the pyrotechnic charge (24) is directly adjacent and includes a contact portion (30) for fastening the retaining means (12). Moreover the invention also comprises an airbag module of a vehicle safety system including such actuator assembly (10).

Abstract: The present invention relates to a polypeptide having interleukin-10 function, comprising two interleukin-10 monomer subunits covalently linked by a linker. The present invention further relates to a nucleic acid molecule encoding the polypeptide of the invention, a vector comprising said nucleic acid molecule, a non-human host transformed with the nucleic acid molecule or the vector of the invention as well as a method for the production of a recombinant polypeptide of the invention. The present invention further relates to a pharmaceutical composition as well as to the polypeptide, the nucleic acid molecule, the vector or the host or host cell of the invention for use in treating and/or preventing inflammatory diseases.

Abstract: A pyrotechnical igniter (100) for an inflator of a vehicle safety system comprises at least two contact pins (102) physically separated from each other by an electrically insulating compound and a bridge wire (110) connected to both contact pins (102) in an electrically conducting manner. A fastening portion (112) in which the bridge wire (110) is welded to the contact pins (102) is provided at each of the contact pins (102).

Abstract: A method for producing a series of base lenses, which cover a predetermined power range, wherein each base lens of the series has a base power different from the base powers of the other base lenses of the series, and has at least one diffractive base grating, the method comprising: specifying the base powers of each base lens of the series; and calculating the base grating of each base lens of the series so as to minimize the color fringe of the respective base lens with the specified base power in a predetermined region of the spectacle lens.

Abstract: A computer-implemented method and a device for optimizing an optical element comprising at least one diffraction grating, wherein at least one refractive surface contributing to the refractive light deflection and/or the at least one diffraction grating of the optical element are/is optimized in such a way as to minimize the color fringe and at least a second-order aberration of the optical element. Also, a corresponding production method and a corresponding device for producing an optical element comprising at least one diffraction grating.

Abstract: A gearbox arrangement (1), which is arranged in a drive train of a multi-axle land vehicle (2), in particular a commercial vehicle, or a similar means of transportation, wherein at least one of said axles is driven, wherein at least one planetary drive (8) is associated with each of the axle halves (5) of a driven axle. The gearbox arrangement comprises at least one sensor device (7) for detecting a steering manipulation on the vehicle (2) and a control device (6).

Abstract: The application relates to an aqueous pharmaceutical formulation comprising 200-1000 U/mL [equimolar to 200-1000 IU human insulin] of insulin glargine.

Abstract: A transplant/implant device for delivering at least one predetermined biologically active compound to a human or animal host system or for another biological function in the host system is produced by genetically engineering vital chondrocytes or mixing chondrocytes with another type of native or genetically engineered cells or mixing chondrocytes with artificial particles having a size comparable to the size of cells or combining at least two of the named steps of engineering or mixing and by subjecting the chondrocytes or the mixture comprising the chondrocytes to three dimensional culture conditions for in vitro production of cartilaginous tissue whereby the cells and/or the artificial particles are immobilized in the cartilaginous tissue. The chondrocytes produce and maintain the cartilaginous tissue and the chondrocytes themselves or cells of another cell type immobilized in the cartilaginous tissue are able to produce and secrete the at least one predetermined compound.

Abstract: Disclosed is a rotor (1) for an electric rotor motor, consisting of a rotor bell (2) with a peripheral wall (4) and at least one one-sided rotor base (6) to enclose a stator, in particular as a part of a motor housing with a high IP rating, for example IP54 per DIN/IEC-EN 60034-5. The rotor bell (2) features a heat sink (12) with high heat conductivity that extends through the rotor base (6) in such a way that the motor heat arising on the inside can be removed via the heat sink (12) through the rotor base (6) to the outside into the environment. Further, the invention relates to an electric rotor motor, in particular with an encapsulated motor housing with a high IP-protection system, for example IP54 per DIN/IEC-EN 60034-5, consisting of a stator and a rotor (1) enclosing the stator in an embodiment of the above-described type.

Abstract: The application relates to an aqueous pharmaceutical formulation comprising 200-1000 U/mL [equimolar to 200-1000 IU human insulin] of insulin glargine.