Patents by Inventor Werner Muller

Werner Muller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6242210
    Abstract: An assay for compounds useful in the treatment of a bacterial induced coagulation disorder has the following steps: a) incubating a plasma sample with a strain of bacteria; b) adding a compound to be assayed to the plasma sample before, during or after step (a); c) conducting an activated partial thromboplastin time test; d) determining the clotting time.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: June 5, 2001
    Assignee: Actinova Limited
    Inventors: Lars Björck, Ulf Sjörbring, Abdelhakim Ben Nasr, Arne Olsén, Heiko Herwald, Werner Müller-Esterl, Eva Mattsson
  • Patent number: 6242247
    Abstract: Cartilage tissue and implants comprising cartilage tissue are produced in vitro starting from cells having the ability to form an extracellular cartilage matrix. Such cells are brought into a cell space (1) and are left in this cell space for producing an extracellular cartilage matrix. The cells are brought into the cell space to have a cell density of ca. 5×107 to 109 cells per cm3 of cell space. The cell space (1) is at least partly separated from a culture medium space (2) surrounding the cell space by a semi-permeable wall (3) or by an open-pore wall acting as convection barrier. The open-pore wall can be designed as a plate (7) made of a bone substitute material and constituting the bottom of the cell space (1).
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: June 5, 2001
    Assignee: Sulzer Orthopedics Ltd.
    Inventors: Franz Rieser, Werner Muller, Pedro Bittmann, Pierre Mainil-Varlet, Christoph P. Saager
  • Patent number: 6221845
    Abstract: Kinin antagonists, especially bradykinin antagonists, can be used for treating bacterial infections, in particular infections caused by bacteria belonging to the genera Streptococcus, Escherichia, Salmonella, Staphylococcus, Klebsiella, Moracella, Haemophilus and Yersinia.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: April 24, 2001
    Assignee: Actinova Limited
    Inventors: Lars Björck, Ulf Sjöbring, Abdelhakim Ben Nasr, Arne Olsén, Heiko Herwald, Werner Müller-Esterl
  • Patent number: 6110178
    Abstract: The apparatus for the production of endochondral or osteochondral bores comprises a combination of a substantially hollow cylindrical sleeve (10), of which one end is formed as a circular cutting edge (11), with a flat borer (20) which is rotatably and axially displaceably arranged in the sleeve (10). Through pressing in of the cutting edge (11) into the tissue, advantageously only into the cartilage tissue, a tissue column is punched out which then is cut away and removed through screwing in of the flat borer (20). In this the boring is done up to the depth of the cutting edge (11) or deeper.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: August 29, 2000
    Assignee: Sulzer Orthopadie AG
    Inventors: Manfred Zech, Werner Muller-Glauser, Christoph Saager, Pierre Mainil-Varlet
  • Patent number: 6062591
    Abstract: In a gas bag module for a vehicle occupant restraint system, a gas generator is held on a trough-shaped carrier part inbetween a diffusor cap, surrounding it, and the base of the carrier part by means of a clamping ring, by which the rim of the inflation opening of a gas bag is fastened to the carrier part.
    Type: Grant
    Filed: June 11, 1998
    Date of Patent: May 16, 2000
    Assignee: TRW Airbag Systems GmbH & Co., KG
    Inventors: Rolf Ruckdeschel, Werner Muller
  • Patent number: 6056319
    Abstract: The invention relates to a gas generator for a safety device, in particular for a vehicle occupant restraint system, comprising a housing of insulating material, a combustion chamber formed in the housing containing solid propellant for the production of hot gas, and with an igniter inserted into the housing and projecting into the combustion chamber. The gas generator is wherein the housing is constructed so as to be conductive in the region of the igniter, and the solid propellant and, optionally, the combustion chamber, is arranged in a conductive container, the conductive region of the housing and the conductive container being in conducting connection with each other.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: May 2, 2000
    Assignee: TRW Airbag Systems GmbH & Co. KG
    Inventors: Rolf Ruckdeschel, Werner Muller
  • Patent number: 5817153
    Abstract: In the method of a photo-oxidative treatment of tissue containing collagen tissue, the tissue is pre-treated with an aqueous conditioning solution prior to an irradiation with light. In this pre-treatment the tissue permeable to the solution is loaded with a dye contained in the solution, in particular with methylene blue. This dye, activated by light, catalyzes photo-oxidative reactions. In accordance with the invention a substance is added to the conditioning solution, the refractive index of which is greater than that of water. As a result of this additive, the tissue containing collagen assumes a greater transparency for light during the pre-treatment.
    Type: Grant
    Filed: October 9, 1996
    Date of Patent: October 6, 1998
    Assignee: Sulzer Innotec AG
    Inventors: Roger Pendl, Werner Muller-Glauser, Peter Bittmann
  • Patent number: 5770651
    Abstract: Oligourethanes containing both anionic and cationic groups may be used as formulating agents for superior aqueous pigment preparations.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: June 23, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Harro Traubel, Hans-Werner Muller, Fritz Novotny
  • Patent number: 5693539
    Abstract: Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. Superior superparamagnetic particles, optionally coated with a polysaccharide or other, usually organic, materials can be prepared in uniform compositions with homogeneous magnetizations. The coating can conveniently be conjugated to a specific binding moiety complementary to a biological material whose purification or separation is desired. In addition, plastic coated matrices which form superior magnetic gradient-intensifying supports are disclosed, along with improved methods and apparatus to conduct HGMS.
    Type: Grant
    Filed: May 31, 1994
    Date of Patent: December 2, 1997
    Inventors: Stefan Miltenyi, Andreas Radbruch, Walter Weichel, Werner Muller, Christoph Gottlinger, Klaus Ludwig Meyer
  • Patent number: 5657128
    Abstract: A defined determination of the field of view observed through a surgical microscope is made. To achieve this determination, the relative current position of the plane of the field of view to the position of an object detail of interest is detected in a sighting method with the aid of a position detection system operating according to the laser triangulation principle. As soon as the plane of the field of view and the object detail are coincident, then with the aid of detected optical system data, the position of the object detail with reference to the surgical microscope is determined and, with the detected coordinates of the surgical microscope, the position of the field of view is determined in space. The position detecting system required for this purpose operates on an optical basis and can be integrated into the optics of the surgical microscope.
    Type: Grant
    Filed: June 24, 1996
    Date of Patent: August 12, 1997
    Assignee: Carl Zeiss-Stiftung
    Inventors: Werner Muller, Joachim Luber
  • Patent number: 5568480
    Abstract: In radio transmission systems having a number of radio channels available for transmission, it is necessary to recognize a transmission channel as idle. One known way of doing this is to measure the field strength on the transmission channel and carry out a threshold decision. As soon as the field strength in a transmission channel is below a preset value, this transmission channel is recognized as idle. In measuring field strength, the field strength is averaged over the entire bandwidth of the transmission channel. As a result, a transmission channel that experiences interference from the signals on its adjacent channels may not be recognized as idle, although the adjacent-channel interference has little effect on the transmission quality. The new method makes it possible to recognize the signal present in a transmission channel by means of numerous narrowband field strength measurements.
    Type: Grant
    Filed: April 11, 1995
    Date of Patent: October 22, 1996
    Assignee: Grundig E.M.V. Elektro-Mechanische Versuchsanstalt Max Grundig
    Inventor: Werner Muller
  • Patent number: 5536244
    Abstract: An endoscopic instrument includes an elongate shaft with an optical system arranged therein. The shaft is closed off at least its distal end by a window which is firmly and tightly connected to the shaft. The closure window is constructed of spinel or yttrium-aluminum-garnet. The spinel may be cubic monocrystalline spinel or polycrystalline spinel, and the yttrium-aluminum-garnet may be undoped or neodymium-doped. Similar closure windows of the same materials may be provided at other openings in the endoscope shaft, such as a proximal end ocular or eyepiece or a lateral light guide window. The closure window may optionally be in the form of a lens to function as part of the optical system.
    Type: Grant
    Filed: June 27, 1994
    Date of Patent: July 16, 1996
    Assignee: Richard Wolf GmbH
    Inventors: Werner Muller, Bernd Pfitzenmeier, Ralf Thiehofe
  • Patent number: 5513005
    Abstract: A defined determination of the field of view observed through a surgical microscope is made. To achieve this determination, the relative current position of the plane of the field of view to the position of an object detail of interest is detected in a sighting method with the aid of a position detection system operating according to the laser triangulation principle. As soon as the plane of the field of view and the object detail are coincident, then with the aid of detected optical system data, the position of the object detail with reference to the surgical microscope is determined and, with the detected coordinates of the surgical microscope, the position of the field of view is determined in space. The position detecting system required for this purpose operates on an optical basis and can be integrated into the optics of the surgical microscope.
    Type: Grant
    Filed: October 11, 1994
    Date of Patent: April 30, 1996
    Assignee: Carl-Zeiss-Stiftung
    Inventors: Werner Muller, Joachim Luber
  • Patent number: 5497739
    Abstract: The invention relates to a kick starting means for change gears, in particular for retrofitting motorcycles of the company Harley-Davidson, U.S.A., with the name "Big Twin", a cubic capacity of about 1340 cm.sup.3 and a five-speed change gear, which has been built since 1980. A kick starting axis 1 is located outside of a gear shaft level 2 formed by a gear drive axle 3 and a gear driven axle 4. This arrangement makes it possible that for retrofitting the aforementioned motorcycles with kick starting means, no modification of the original exhaust pipe assembly is necessary. (FIG.
    Type: Grant
    Filed: June 29, 1994
    Date of Patent: March 12, 1996
    Inventor: Werner Muller
  • Patent number: 5462853
    Abstract: Anti-viral material comprising a mannose-specific lectin obtained from a bulb of the plant family Amaryllidaceae, for example Narcissus pseudonarcissus, and the use of this material to produce a medicament and a vaccine. The material is effective against RNA viruses which contain glycoproteins with mannose (alpha-1>3) or (alpha-1>6) mannose linkages, for example HIV or HTLV such a Human Immunodeficiency Virus (HIV) and Human T Lymphotropic Virus (HTLV) and can also be used as a diagnostic.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: October 31, 1995
    Assignee: Scottish Crop Research Institute
    Inventors: Derek Stewart, John M. S. Forrest, Werner Muller
  • Patent number: 5453186
    Abstract: The invention is directed to separating materials comprising a primary or secondary aliphatic hydroxyl group-containing support coated with at least one covalently bonded polymer, wherein(1) the covalently bonded polymers are bonded to the support by graft polymerization via the .alpha.-carbon atoms of the hydroxyl groups, and(2) the polymer contains identical or different recurring units of the formula I ##STR1## wherein R.sup.1 is H or CH.sub.3 ;Y is ##STR2## R' and R" are each independently H or CH.sub.3, R.sup.2 and R.sup.3 are each independently(a) C.sub.1-10 -alkyl, phenyl, phenyl-C.sub.1-10 -alkyl, cycloalkyl, C.sub.1-10 -alkyl-cycloalkyl or C.sub.1-10 -alkylphenyl,(b) one of the above groups in (a) monosubstituted or polysubstituted by each of amino, mono- or dialkylamino, trialkylammonium, carboxyl, or sulfonyl,(c) a cyclic or bicyclic radical having 5-10 C atoms, wherein one or more CH or CH.sub.2 groups is replaced by (i) N or NH, (ii) N or NH and S, or (iii) N or NH and O, or(d) one of R.sup.
    Type: Grant
    Filed: January 20, 1995
    Date of Patent: September 26, 1995
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Werner Muller, Joachim Kinkel
  • Patent number: 5414973
    Abstract: An apparatus for conveying a textile product from an upstream to a downstream station, especially for delivery into a package, has an endless conveyor belt driven by a drive and a pressure unit, the textile product being conveyed while held in a gripped manner between conveyor belt and pressure unit. To achieve rapid conveyance of the textile product without thereby impairing it, it is proposed that the conveyor belt be configured as a first telescoping belt, the front end of which, facing the downstream station, can move back and forth in the direction of the downstream station while the pressure unit follows this motion synchronously; and that the drive be controlled so that the belt of the telescoping belt is not driven as the front end moves back from the downstream station, and thereby rolls off the textile product.
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: May 16, 1995
    Assignee: August Krempel Sohne GmbH & Co.
    Inventor: Werner Muller
  • Patent number: 5396898
    Abstract: The method of comminution of soft tissue (4) from animal or human bodies is performed by a mechanism (10) which exhibits a supply vessel (1), cutter member (2) and collector (3) and forms a closure impermeable to germs against the environment The tissue is removed from the body in a sterile environment, and filled into the supply vessel of the opened mechanism. After the supply vessel has been assembled together with the clutter member and the collector into a mechanism ready for operation, by the employment of pressure-exerting means, preferably compressed gas (11'), the tissue is delivered from the supply vessel into the collector, the tissue being comminuted at the same time by the cutter member.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: March 14, 1995
    Assignee: Sulzer Medizinaltechnik AG
    Inventors: Peter Bittmann, Daniel Nadler, Werner Muller-Glauser
  • Patent number: 5385707
    Abstract: Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. Superior superparamagnetic particles, optionally coated with a polysaccharide or other, usually organic, materials can be prepared in uniform compositions with homogeneous magnetizations. The coating can conveniently be conjugated to a specific binding moiety complementary to a biological material whose purification or separation is desired. In addition, plastic coated matrices which form superior magnetic gradient-intensifying supports are disclosed, along with improved methods and apparatus to conduct HGMS.
    Type: Grant
    Filed: January 21, 1993
    Date of Patent: January 31, 1995
    Assignee: Stefan Miltenyi
    Inventors: Stefan Miltenyi, Andreas Radbruch, Walter Weichel, Werner Muller, Christoph Gottlinger, Klaus L. Meyer
  • Patent number: 5359417
    Abstract: A defined determination of the field of view observed through a surgical microscope is made. To achieve this determination, the relative current position of the plane of the field of view to the position of an object detail of interest is detected in a sighting method with the aid of a position detection system operating according to the laser triangulation principle. As soon as the plane of the field of view and the object detail are coincident, then with the aid of detected optical system data, the position of the object detail with reference to the surgical microscope is determined and, with the detected coordinates of the surgical microscope, the position of the field of view is determined in space. The position detecting system required for this purpose operates on an optical basis and can be integrated into the optics of the surgical microscope.
    Type: Grant
    Filed: October 15, 1992
    Date of Patent: October 25, 1994
    Assignee: Carl-Zeiss-Stiftung
    Inventors: Werner Muller, Joachim Luber