Abstract: Disclosed are a combined formulation kit for analyzing the phenotype and function of a CD1c+ dendritic cell subset and the use thereof, wherein the detection objects of the kit include CD1c, CD40, IL-6 and IL-10. The kit can be used to efficiently and quickly identify the phenotype of a CD1c+ dendritic cell subset in peripheral blood and analyze the function thereof, thereby ensuring accuracy and reducing the economic cost produced by detecting a large number of surface antigen molecules, and the detection method is also simple to implement.

Abstract: The present invention discloses an executive system for driving a valve to open and close, comprising a first housing, a linkage block, a first drive rod and a drive mechanism. Wherein, the first housing has a first inner cavity; a medium channel is provided in a side wall of the first housing; an outer peripheral wall of the linkage block is arranged on a wall of the first inner cavity in a slidable and sealed manner, and the linkage block partitions the first inner cavity into an upper cavity and a lower cavity; the medium channel is communicated with the upper cavity; a bottom part of the first drive rod sequentially passes through a top part of the first housing and the linkage block and extends into the lower cavity; a position-limiting part on the bottom part of the first drive rod blocks the linkage block within a region between the position-limiting part and the top part of the first housing; the drive mechanism is provided on top of the first drive rod.

Abstract: Implants comprising an antimalarial agent such as decoquinate or another therapeutic drug are disclosed. The implants can be in the form of a complex comprising a drug, a lipid or lipids and optionally a polymer carrier. The present invention provides methods for preparing implants wherein the implants comprise decoquinate or another therapeutic drug, and a lipid or lipids such as cholesterol, monoglycerides, or diglycerides, and optionally a small percentage of a biocompatible polymer based on the total implant weight. The implants are useful for releasing a therapeutic drug at a constant level and maintaining a prophylactic or therapeutic level of the drug in a subject, for preventing a malarial infection or treating other diseases or disorders.

Abstract: A composite filter cartridge, comprising a filter cartridge body provided with two filter devices. Each filter device is respectively provided with a support component which fixes the filter device, and the filter devices are arranged in a linear manner and fixed with respect to one another. Each filter device is respectively provided with an independent housing, a filter module and a filter water channel, the filter module and the filter water channel being arranged within the housing, the filter water channel sequentially comprising a water inlet cavity and a water outlet cavity, the water inlet cavity and the water outlet cavity being connected via the corresponding filter module.

Abstract: Provided are a chimeric antigen receptor and an application thereof; said chimeric antigen receptor contains a domain which identifies any one of, or a combination of at least two of, the malarial protein VAR2CSA, a protein tag on malarial protein VAR2CSA, or a compound capable of labeling the malarial protein VAR2CSA. The chimeric antigen receptor can identify the VAR2CSA protein or the recombinant protein (rVAR2) of any one of, or at least two of, the domains of the VAR2CSA protein which can bind to placental-like chondroitin sulfate A (pl-CSA). The VAR2CSA protein or rVAS2 protein is capable of targeting several different types of tumor cells by means of binding to the pl-CSA on the surface of the tumor cell.

Abstract: Disclosed are an attenuation system and the use thereof for attenuating plasmodia, specifically the use of an EF1g gene for attenuating plasmodia. The attenuation system regulates the expression or degradation of the EF1g gene by using a regulatory system, thereby controlling the growth of plasmodia and achieving the attenuation of plasmodia.

Abstract: Disclosed is a water purifier having a light-emitting assembly, comprising a light-emitting assembly (1), an outer housing (2), a middle frame (3) and a top cover (4). The light-emitting assembly (1) comprises a light ring support (11) and a light-emitting component mounted on the light ring support (11). The light-emitting assembly (1) is assembled on the middle frame (3). The middle frame (3), the light-emitting assembly (1) and the outer housing (2) are successively arranged from inside to outside. The top cover (4) is provided above the middle frame (3) and/or the outer housing (2), and the light ring support (11) is adjacent to or abuts the position of the top cover (4). The light-emitting assembly (1) of the water purifier emits light when lit, forming a uniform light-emission ring of emitted light at the top part of the light ring support (11), and can also be used for lighting.

Abstract: Disclosed is a filter core water flow channel, comprising a filter core housing (1), the filter core housing (1) respectively comprising an upper area (1) and a lower area (12) in mutual communication according to high to low positions, the upper area (11) being provided with a front filter core (2), the lower area (12) being provided with a kernel filter core (3), the filter core housing (1) further being provided with a water inlet (5) and a water outlet (6), the water inlet (5) being in communication with the upper area (11) via the lower area (12) around the kernel filter core (3), water passing through the water inlet (5) and the lower area (12) surrounding the kernel filter core (3) and entering the upper area (11), and after filtering by the front filter core (2), water then flowing into the kernel filter core (3), and finally flowing out via the water outlet (6).

Abstract: Disclosed is an improved filter core structure, comprising a filter core housing (1), the filter core housing (1) respectively comprising an upper area (11) and a lower area (12) according to high to low positions, the upper area (11) and the lower area (12) being in mutual communication, the upper area (11) being provided with a front filter core (2), the lower area (12) being provided with a kernel filter core (3), and the front filter core (2) comprising at least two filtering materials, and an inner layer core (21) and an outer layer core (22) provided according to position from inside to outside.

Abstract: Hot-melt extrusion for producing solid solution comprising nanoparticle formulation of decoquinate is disclosed. Aqueous phase comprising the nanoparticles of hot-melt extruding products is homogeneous and stable. Provided is the composition comprising the solid solution of decoquinate and a method of hot-melt extrusion for producing this composition comprising the solid dispersion of decoquinate. Furthermore, provided is the solid solution comprising nanosized decoquinate formulation having improved water solubility and enhanced delivery of decoquinate in digestive system for absorption, increasing bioavailability, and the efficacy against malaria at the liver stage.

Abstract: Implants comprising an antimalarial agent such as decoquinate or another therapeutic drug are disclosed. The implants can be in the form of a complex comprising a drug, a lipid or lipids and optionally a polymer carrier. The present invention provides methods for preparing implants wherein the implants comprise decoquinate or another therapeutic drug, and a lipid or lipids such as cholesterol, monoglycerides, or diglycerides, and optionally a small percentage of a biocompatible polymer based on the total implant weight. The implants are useful for releasing a therapeutic drug at a constant level and maintaining a prophylactic or therapeutic level of the drug in a subject, for preventing a malarial infection or treating other diseases or disorders.

Abstract: An electric valve and a control method therefor are disclosed. The electric valve comprises a mechanical valve body, a motor (1), a valve switch state detection apparatus, a control line (9) and a control circuit (80). The motor and the mechanical valve body are in transmission connection; the control line is electrically connected to the control circuit; the control circuit comprises a drive module (2) and a power supply module (5); and the motor, the valve switch state detection apparatus and the power supply module are respectively connected to the drive module. The control circuit further comprises a backup power supply (90) electrically connected thereto.

Abstract: Methods for associating detection information of an ultrasound system includes receiving an ROI (region of interest) and an image display type that are selected by an operator on an image detected by the ultrasound system, performing motion tracking for the ROI to obtain tracking information, configuring the image detected by the ultrasound system and position information of the ROI in a first display area of a display device for displaying, configuring quantitative parameter information related to the image in a second display area of the display device for displaying selecting an image model according to the image display type, and configuring the image model in a third display area of the display device for displaying. The methods can display detection information obtained by the ultrasound system on the display device more intuitively.

Abstract: The present invention relates to the field of treatment of tumor, and especially to a composition comprising a plasmodium, a treatment method and an application thereof. The composition of the present invention has therapeutic effects on colorectal carcinoma, lung carcinoma, breast carcinoma, gastric carcinoma and hepatic carcinoma etc., can inhibit the growth of tumor and prolong the life of the tumor patients, whereas has no therapeutic effect on melanoma and lymphoma; meanwhile, the present invention describes that the long-term plasmodium infection has better therapeutic effect on tumors, and the plasmodium immunotherapy of the present invention does not take the fever time as a course standard when treating tumors, but should be used to extend the duration of plasmodium infection as much as possible until the progression of tumors can be controlled under the premise of protecting the organ functions and life safety of the patients.

Abstract: A clock dividing frequency circuit can include: a controlled current source configured to generate a driving current that varies with a dividing frequency control signal; a ramp signal generating circuit configured to generate a ramp signal having a slope that varies according to the driving current, where the ramp signal is reset according to pulses of a dividing frequency clock signal; and a dividing frequency pulse generating circuit configured to generate the dividing frequency clock signal by a dividing frequency operation according to the ramp signal and a system clock signal.

Abstract: Polymeric coatings, their applications, and the methods of their preparation are described. The coatings may be used to confer desirable properties to the consumer and/or medical products. Also described are methods of loading therapeutic agents on the polymeric coatings and the applications of the drug eluting polymeric coatings thus obtained.

Abstract: The present invention discloses an executive system for driving a valve to open and close, comprising a first housing, a linkage block, a first drive rod and a drive mechanism. Wherein, the first housing has a first inner cavity; a medium channel is provided in a side wall of the first housing; an outer peripheral wall of the linkage block is arranged on a wall of the first inner cavity in a slidable and sealed manner, and the linkage block partitions the first inner cavity into an upper cavity and a lower cavity; the medium channel is communicated with the upper cavity; a bottom part of the first drive rod sequentially passes through a top part of the first housing and the linkage block and extends into the lower cavity; a position-limiting part on the bottom part of the first drive rod blocks the linkage block within a region between the position-limiting part and the top part of the first housing; the drive mechanism is provided on top of the first drive rod.

Abstract: Disclosed is a water system having a UV function, comprising a water route (, a water flow sensor (2), a filter core assembly (3), a UV sterilising device (4), a solenoid valve (5) and an electric control device (6), wherein the electric control device (6) is respectively electrically connected to the water flow sensor (2), the UV sterilising device (4) and the solenoid valve (5), the electric control device (6) receives a water flow signal transmitted from the water flow sensor (2), and, according to the water flow signal, controls the operation of the UV sterilising device (4) and the solenoid valve (5) When sensing a signal that water flow is passing through the water route, the water system having a UV function automatically starts the UV sterilising device (4) and the solenoid valve (5), conversely, when the signal indicate that no water flow is passing through the water route, the UV sterilising device (4) and the solenoid valve (5) are shut down, preventing the UV sterilising device (4) from conducting

Abstract: Disclosed are a filter element and a filter device using the filter element. The filter element includes: a base, wherein the base is installed on the filter device, and a first passage and a second passage are disposed at least partially in the base; and a filter body, wherein the filter body is detachably connected to an upper part of the base, the filter body has a filter space therein, a first filter passage and a second filter passage are connected and arranged on the two ends of the filter space, and a filter material for filtration is provided in the filter space. When the filter element is in a working state, the first filter passage and the first passage are connected for fluid communication, and the second filter passage and the second passage are connected for fluid communication.

Abstract: A control circuit for generating a switching control signal to control switching operations of a power switch in a power stage circuit, can include: a first control loop configured to receive a first voltage feedback signal, and to generate a first compensation signal; a voltage regulating circuit configured to receive an output voltage signal of the power stage circuit, and to generate a second compensation signal according to a difference between an output voltage signal of the power stage circuit during different time periods; and control and driving circuit configured to receive the first and second compensation signals and a sense voltage signal that represents a current through an inductor of the power stage circuit, and to generate an OFF signal, and a switching control signal according to the OFF signal and an ON signal.