Patents by Inventor Xiaoyun Wu
Xiaoyun Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11974590Abstract: The patent discloses halophilic bacteria and a method for fermenting fish paste, belonging to the technical field of solid-state fermentation of aquatic products using microorganisms. Four kinds of screened halophilic bacteria were used as mixed starter culture to produce fish paste. The effects of the ratio of mixed starter culture, inoculation amount, fermentation temperature, fermentation time and salinity on fish paste were studied by determining physical and chemical indexes and performing sensory evaluation. The fish paste has the characteristics of high safety, low salinity, high flavor and nutrition value. This method of fish paste processing needs short fermentation time. The fermented products of fish paste with better flavor can be obtained by using the mixed starter culture.Type: GrantFiled: March 29, 2019Date of Patent: May 7, 2024Assignee: Jiangsu UniversityInventors: Ruichang Gao, Zhiying Zheng, Li Yuan, Xiaoyun Wu, Qiaozhen Zhou, Qian Chu
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Patent number: 11965070Abstract: The disclosure relates to the field of electronic materials, and in particular to a composite film of fluorinated polybenzoxazole (6FPBO) and triple-shelled mesoporous silica hollow spheres, and to its preparation and use. The composite film comprises fluorinated polybenzoxazole as a matrix and amino-functionalized triple-shelled mesoporous silica hollow spheres which are dispersed in the fluorinated polybenzoxazole matrix. A mass ratio of (amino-functionalized triple-shelled mesoporous silica hollow spheres)/(fluorinated polybenzoxazole) is 1/100 to 5/100. The composite film has excellent thermal stability and a lower dielectric constant.Type: GrantFiled: November 1, 2021Date of Patent: April 23, 2024Assignee: East China University of Science and TechnologyInventors: Qixin Zhuang, Zhe Zhang, Xiaoyun Liu, Jian Xu, Wentao Wang, Zeyang Wu, Xiaohan Wu, Lihui Li
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Publication number: 20240102037Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, enhanced nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.Type: ApplicationFiled: July 26, 2023Publication date: March 28, 2024Inventors: Paolo Castiglioni, Jaishree M. Chittoor-Vijayanath, Barry S. Goldman, Robert J. Meister, Monnanda S. Rajani, G. Ramamohan, Naveen Silvester, Tyamagondlu V. Venkatesh, Jingrui Wu, Xiaoyun Wu
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Publication number: 20240074282Abstract: The present application provides a displaying base plate and a displaying device, which relates to the technical field of displaying. The displaying device can ameliorate the problem of screen greening caused by electrostatic charges, thereby improving the effect of displaying. The displaying base plate includes an active area and a non-active area connected to the active area, the non-active area includes an edge region and a first-dam region, and the first-dam region is located between the active area and the edge region; the displaying base plate further includes: a substrate; an anti-static layer disposed on the substrate, wherein the anti-static layer is located at least within the edge region; and a driving unit and a touch unit that are disposed on the substrate, wherein the driving unit is located within the active area.Type: ApplicationFiled: August 23, 2022Publication date: February 29, 2024Applicants: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Yu Zhao, Yong Zhuo, Wei He, Yanxia Xin, Qun Ma, Xiping Li, Jianpeng Liu, Kui Fang, Cheng Tan, Xueping Li, Yihao Wu, Xiaoyun Wang, Haibo Li, Xiaoyan Yang
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Patent number: 11912754Abstract: The present application provides an antibody fusion protein comprising a vascular endothelial growth factor receptor (VEGFR) fused to the C-terminus of the antibody light chain. Also provided are methods of making and using these antibody fusion proteins.Type: GrantFiled: October 11, 2018Date of Patent: February 27, 2024Assignee: IMMUNOWAKE INC.Inventor: Xiaoyun Wu
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Publication number: 20240002872Abstract: This disclosure provides recombinant DNA constructs and transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.Type: ApplicationFiled: September 18, 2023Publication date: January 4, 2024Inventors: Mark S. Abad, Erin Bell, Paul S. Chomet, Todd DeZwaan, Stephen M. Duff, Barry S. Goldman, Hongwu Jia, Lloyd Jones, Balasulojini Karunanandaa, Saritha V. Kuriakose, Linda L. Lutfiyya, Savitha Madappa, Zoe P. McKiness, Donald E. Nelson, Sasha Preuss, Monnanda Somaiah Rajani, Dhanalakshmi Ramachandra, Aniruddha Raychaudhuri, Daniel P. Schachtman, Steven H. Schwartz, Char Shobha, Matthew M. Tanzer, Tyamagondlu V. Venkatesh, Huai Wang, Xiaoyun Wu
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Publication number: 20230416769Abstract: The present disclosure provides modified, transgenic, or genome edited/mutated corn plants that are semi-dwarf and have one or more improved ear traits relative to a control plant, such as increase in ear diameter, ear fresh weight, and single kernel weight, and increased yield. The modified, transgenic, or genome edited/mutated corn plants comprise a transgene encoding one or more molybdenum cofactor (Moco) biosynthesis polypeptides and have a reduced expression of one or more GA20 or GA3 oxidase genes. Also provided are methods for producing the modified, transgenic, or genome edited/mutated corn plants.Type: ApplicationFiled: July 7, 2023Publication date: December 28, 2023Applicants: Monsanto Technology LLC, BASF Plant Science LP, BASF Plant Science Company GmbHInventors: Charles R. DIETRICH, Natalia IVLEVA, Thomas L. SLEWINSKI, Hong LI, Jaishree CHITTOOR, Xiaoyun WU, Wesley B. BRUCE, Leonardo ALVES-JUNIOR
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Publication number: 20230405015Abstract: The present invention provides a method of treatment of sarcoma comprising administering to a patient in need thereof a compound of general formula (I), in which R1, R2, R3, and R4, are as defined herein, alone or in pharmaceutical compositions or combinations comprising said compounds as a sole agent or in combination with other active ingredients.Type: ApplicationFiled: August 31, 2023Publication date: December 21, 2023Applicants: Bayer Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.Inventors: Martin LANGE, Stefan KAULFUSS, Charlotte Christine KOPITZ, Heidi GREULICH, Xiaoyun WU, Matthew MEYERSON
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Publication number: 20230354762Abstract: Provided are compositions and methods for reducing, disrupting, or altering ZmDA1 activity in corn plants. Methods and compositions are also provided for producing modifications in the ZmDA1 gene through mutagenesis and/or editing. Modified plant cells and plants having a modification in the ZmDA1 gene are further provided comprising improved characteristics, such as increased yield.Type: ApplicationFiled: March 27, 2023Publication date: November 9, 2023Inventors: Steven Beach, Sivalinganna Manjunath, Linda Rymarquis, Thomas L. Slewinski, Xiaoyun Wu
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Publication number: 20230340517Abstract: Provided are compositions and methods for reducing, disrupting, or altering ZmGW2 activity in corn plants. Methods and compositions are also provided for producing modifications in the ZmGW2 gene through mutagenesis and/or editing. Modified plant cells and plants having a modification in the ZmGW2 gene are further provided comprising improved characteristics, such as increased yield.Type: ApplicationFiled: March 27, 2023Publication date: October 26, 2023Inventors: Steven Beach, Sivalinganna Manjunath, Linda Rymarquis, Thomas L. Slewinski, Xiaoyun Wu
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Publication number: 20230313216Abstract: Provided are compositions and methods for reducing, disrupting, or altering ZmDA2 activity in corn plants. Methods and compositions are also provided for producing modifications in the ZmDA2 gene through mutagenesis and/or editing. Modified plant cells and plants having a modification in the ZmDA2 gene are further provided comprising improved characteristics, such as increased yield.Type: ApplicationFiled: March 27, 2023Publication date: October 5, 2023Inventors: Steven Beach, Sivalinganna Manjunath, Linda Rymarquis, Thomas L. Slewinski, Xiaoyun Wu
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Patent number: 11773070Abstract: The present invention provides dihydrooxydiazinone compounds of general formula (I) in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.Type: GrantFiled: July 14, 2022Date of Patent: October 3, 2023Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.Inventors: Manuel Ellermann, Stefan Nikolaus Gradl, Charlotte Christine Kopitz, Martin Lange, Adrian Tersteegen, Philip Lienau, Christa Hegele-Hartung, Detlev Sülzle, Timothy A. Lewis, Heidi Greulich, Xiaoyun Wu, Matthew Meyerson, Alex Burgin
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Publication number: 20230167164Abstract: The present application relates to immunocytokines comprising a cytokine or variant thereof positioned at the hinge region of a heavy chain of an antibody (e.g., full-length antibody), or positioned at a hinge region between an antigen-binding fragment (e.g., ligand, receptor, or antibody fragment) and an Fc domain subunit or portion thereof, methods of making, and uses thereof.Type: ApplicationFiled: January 19, 2023Publication date: June 1, 2023Applicant: Immunowake Inc.Inventors: Ellen WU, Xiaoyun WU, John WAKEFIELD
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Publication number: 20230017200Abstract: The present invention provides dihydrooxydiazinone compounds of general formula (I): in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.Type: ApplicationFiled: July 11, 2022Publication date: January 19, 2023Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.Inventors: Manuel ELLERMANN, Stefan Nikolaus GRADL, Charlotte Christine KOPITZ, Martin LANGE, Adrian TERSTEEGEN, Philip LIENAU, Christa HEGELE-HARTUNG, Detlev SÜLZLE, Timothy A. LEWIS, Heidi GREULICH, Xiaoyun WU, Matthew MEYERSON, Alex BURGIN
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Publication number: 20220396554Abstract: The present invention provides dihydrooxydiazinone compounds of general formula (I) in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.Type: ApplicationFiled: July 14, 2022Publication date: December 15, 2022Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.Inventors: Manuel ELLERMANN, Stefan Nikolaus GRADL, Charlotte Christine KOPITZ, Martin LANGE, Adrian TERSTEEGEN, Philip LIENAU, Christa HEGELE-HARTUNG, Detlev SÜLZLE, Timothy A. LEWIS, Heidi GREULICH, Xiaoyun WU, Matthew MEYERSON, Alex BURGIN
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Publication number: 20220348650Abstract: The present invention provides an anti-TIGIT immunosuppressant and use thereof. The immunosuppressant can bind to the extracellular region of human TIGIT, and can be used for treating diseases such as a cancer.Type: ApplicationFiled: September 3, 2020Publication date: November 3, 2022Inventors: Junjie Huang, Xiaoyun Wu, Zhenqian Xu, Shide Liang, Shengfeng Li, Jin-Chen Yu, Xianming Huang
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Publication number: 20220291203Abstract: The disclosure provides for compositions, methods, and kits for evaluating the effect of a cell-killing agent on a population of tumor cells (e.g., tumor cells that can inducibly express reporter protein).Type: ApplicationFiled: July 24, 2020Publication date: September 15, 2022Inventors: Ellen WU, Xiaoyun WU, John WAKEFIELD
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Patent number: 11427553Abstract: The present invention provides dihydrooxydiazinone compounds of general formula (I): in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.Type: GrantFiled: August 2, 2018Date of Patent: August 30, 2022Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.Inventors: Manuel Ellermann, Stefan Nikolaus Gradl, Charlotte Christine Kopitz, Martin Lange, Adrian Tersteegen, Philip Lienau, Christa Hegele-Hartung, Detlev Sülzle, Timothy A. Lewis, Heidi Greulich, Xiaoyun Wu, Matthew Meyerson, Alex Burgin
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Publication number: 20220154201Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, enhanced nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.Type: ApplicationFiled: February 1, 2022Publication date: May 19, 2022Applicant: Monsanto Technology LLCInventors: Paolo CASTIGLIONI, Jaishree M. CHITTOOR-VIJAYANATH, Barry S. GOLDMAN, Robert J. MEISTER, Monnanda S. RAJANI, G. RAMAMOHAN, Naveen SILVESTER, Tyamagondlu V. VENKATESH, Jingrui WU, Xiaoyun WU
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Publication number: 20220106606Abstract: This disclosure provides recombinant DNA constructs and transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.Type: ApplicationFiled: October 21, 2021Publication date: April 7, 2022Inventors: Mark S. Abad, Erin Bell, Paul S. Chomet, Todd DeZwaan, Stephen M. Duff, Barry S. Goldman, Hongwu Jia, Lloyd Jones, Balasulojini Karunanandaa, Saritha V. Kuriakose, Linda L. Lutfiyya, Savitha Madappa, Zoe P. McKiness, Donald E. Nelson, Sasha Preuss, Monnanda Somaiah Rajani, Dhanalakshmi Ramachandra, Aniruddha Raychaudhuri, Daniel P. Schachtman, Steven H. Schwartz, Char Shobha, Matthew M. Tanzer, Tyamagondlu V. Venkatesh, Huai Wang, Xiaoyun Wu