Patents by Inventor Xiaoyun Wu

Xiaoyun Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS
    Publication number: 20200165251
    Abstract: Provided herein are antibacterial compounds represented by Formula I, or a pharmaceutically acceptable salt thereof, wherein X, Y, R4, R5, and R6 are as defined herein. Also provided are pharmaceutical compositions comprising the compounds of Formula I.
    Type: Application
    Filed: May 8, 2018
    Publication date: May 28, 2020
    Inventors: Janelle Comita-Prevoir, Thomas Francois Durand-Reville, Satenig Guler, Jan Romero, Mark Sylvester, Ruben Tommasi, Camilo Velez-Vega, Xiaoyun Wu, Jing Zhang
  • COMPOUNDS, COMPOSITIONS AND METHODS FOR CANCER TREATMENT
    Publication number: 20200062741
    Abstract: The present invention features improved compounds, especially the compound having the structure (1). Compositions and methods of identifying patients having cancer using biomarkers (e.g., PDE3A, PDE3B, SLFN12 and/or CREB3L1) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention.
    Type: Application
    Filed: February 1, 2018
    Publication date: February 27, 2020
    Applicants: THE BROAD INSTITUTE, INC., DANA-FARBER CANCER INSTITUTE, INC., BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: TIMOTHY A. LEWIS, XIAOYUN WU, HEIDI GREULICH, MATTHEW MEYERSON, MANUEL ELLERMANN, PHILIP LIENAU, KNUT EIS, ANTJE MARGRET WENGNER, CHARLOTTE CHRISTINE KOPITZ, MARTIN LANGE
  • Transgenic Plants With Enhanced Traits
    Publication number: 20190382782
    Abstract: This disclosure provides recombinant DNA constructs and transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Application
    Filed: May 20, 2019
    Publication date: December 19, 2019
    Inventors: Mark S. Abad, Erin Bell, Paul S. Chomet, Todd DeZwaan, Stephen M. Duff, Barry S. Goldman, Hongwu Jia, Lloyd Jones, Balasulojini Karunanandaa, Saritha V. Kuriakose, Linda L. Lutfiyya, Savitha Madappa, Zoe P. McKiness, Donald E. Nelson, Sasha Preuss, Monnanda Somaiah Rajani, Dhanalakshmi Ramachandra, Aniruddha Raychaudhuri, Daniel P. Schachtman, Steven H. Schwartz, Char Shobha, Matthew M. Tanzer, Tyamagondlu V. Venkatesh, Huai Wang, Xiaoyun Wu
  • COMPOUNDS, COMPOSITIONS AND METHODS FOR CANCER PATIENT STRATIFICATION AND CANCER TREATMENT
    Publication number: 20190365770
    Abstract: The present invention features improved Compounds, especially (I) methods of identifying patients having Cancer using biomarkers (e.g., PDE3A, SLFN12 and/or CREB3L1) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., Compounds 1-6 disclosed herein).
    Type: Application
    Filed: February 3, 2017
    Publication date: December 5, 2019
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, THE BROAD INSTITUTE, INC., DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: TIMOTHY A. LEWIS, ALEX BURGIN, MONICA SCHENONE, XIAOYUN WU, HEIDI GREULICH, MATTHEW MEYERSON, LUC DE WAAL, ANTJE MARGRET WENGNER, KNUT EIS, PHILLIP LIENAU, ULRIKE SACK, MARTIN LANGE
  • LOW OVERHEAD SUBBAND PHYSICAL DOWNLINK CONTROL FOR COMMUNICATION SYSTEMS
    Publication number: 20190349153
    Abstract: An apparatus is configured to be employed within a base station. The apparatus comprises baseband circuitry which includes a radio frequency (RF) interface and one or more processors. The one or more processors are configured to obtain channel information and data information for a user equipment (UE) device, determine control information for the UE device based on the obtained channel information and data information, generate a channel format for the determined control information and having varied subband sizes, and provide the channel format to the RF interface for a downlink transmission to the UE device.is configured to be employed within a base station.
    Type: Application
    Filed: December 29, 2017
    Publication date: November 14, 2019
    Inventors: Qian Li, Guangjie Li, Xiaoyun Wu, Geng Wu
  • Method and apparatus for automatic processing of service requests on an electronic device
    Patent number: 10394577
    Abstract: Embodiments of the present application provides methods and apparatus capable of recording operation/display events on a mobile device used to fulfill a first service request entered via a user interface of the mobile device. A recorded sequence of operation/display events is used to build a script file, which is associated with the service request or a template extracted from the service request. When a second service request that is the same or similar to the first service request is received again on the same or different mobile device, the script file associated with the service request is retrieved and provided to the mobile device, which executes the script file to automatically brings up a series of operation/display events to fulfill the service request. Thus, a user of the mobile device does not need to manually navigate through the sequence of operation/display events again in order to fulfill the service request.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: August 27, 2019
    Assignee: Deepassist Inc.
    Inventor: Xiaoyun Wu
  • Method and apparatus for automatic processing of service requests on an electronic device
    Patent number: 10372512
    Abstract: Embodiments of the present application provides methods and apparatus capable of recording operation/display events on a mobile device used to fulfill a service request. A recorded sequence operation/display events is used to build a script file, which is associated with the service request. When the same or similar service request is received again, the script file associated with the service request is retrieved and the mobile device automatically brings up a series of operation/display events according to the script file so that a user of the mobile device does not need to manually navigate through the sequence of operation/display events again in order to fulfill the service request.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: August 6, 2019
    Assignee: Deepassist Inc.
    Inventor: Xiaoyun Wu
  • BETA-LACTAMASE INHIBITOR COMPOUNDS
    Publication number: 20190202832
    Abstract: The present invention is directed to compounds which are beta-lactamase inhibitors. The compounds and their pharmaceutically acceptable salts are useful in combination with beta-lactam antibiotics, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of R1, R2, R3, R4, R5 and R6 are described herein.
    Type: Application
    Filed: September 15, 2017
    Publication date: July 4, 2019
    Applicants: Entasis Therapeutics Limited, Entasis Therapeutics Limited
    Inventors: Gregory S. Basarab, Janelle Comita-Prevoir, Thomas Francois Durand-Reville, Lise Gauthier, Bill Moss, John O'Donnell, Jan Romero, Ruben Tommasi, Jeroen Cunera Verheijen, Frank Wu, Xiaoyun Wu, Jing Zhang
  • Transgenic plants with enhanced traits
    Patent number: 10323253
    Abstract: This disclosure provides recombinant DNA constructs and transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: June 18, 2019
    Assignee: Monsanto Technology LLC
    Inventors: Mark S. Abad, Erin Bell, Paul S. Chomet, Todd DeZwaan, Stephen Duff, Barry S. Goldman, Hongwu Jia, Lloyd Jones, Balasulojini Karunanandaa, Saritha V. Kuriakose, Linda L. Lutfiyya, Savitha Madappa, Zoe P. McKiness, Donald E. Nelson, Sasha Preuss, Monnanda S. Rajani, Dhanalakshmi Ramachandra, Aniruddha Raychaudhuri, Daniel P. Schachtman, Steven H. Schwartz, Char Shobha, Matthew M. Tanzer, Tyamagondlu V. Venkatesh, Huai Wang, Xiaoyun Wu
  • EX VIVO EXPANSION METHOD FOR CORD BLOOD NK CELL, AND KIT AND APPLICATION THEREOF
    Publication number: 20190112577
    Abstract: Provides an ex vivo expansion method for a cord blood NK cell, and a kit and application thereof. The ex vivo expansion method for the cord blood NK cell comprises: separating a cord blood monocyte; activating, culturing, and proliferation; and culturing of the cord blood NK cell. The invention does not require cell sorting and does not require a trophoblast. A reagent in the kit does not contain animal-based component. The invention provides a high production volume of the NK cell. The cord blood NK cell obtained has at least 90% purity, a total cell count of up to 1010-11 per part of cord blood, and can kill a tumor cell effectively.
    Type: Application
    Filed: May 6, 2016
    Publication date: April 18, 2019
    Inventors: Xiaoyun WU, Xuemin LIU, Huiyan KANG, Yunhong WANG, Xiaoxiang FAN, Zhigang LI, Wei DING, Lihua WU, Jinyan LI, Dianfu SHEN, Huizhen ZHANG
  • METHOD AND APPARATUS FOR AUTOMATIC PROCESSING OF SERVICE REQUESTS ON AN ELECTRONIC DEVICE
    Publication number: 20190102208
    Abstract: Embodiments of the present application provides methods and apparatus capable of recording operation/display events on a mobile device used to fulfill a first service request entered via a user interface of the mobile device. A recorded sequence of operation/display events is used to build a script file, which is associated with the service request or a template extracted from the service request. When a second service request that is the same or similar to the first service request is received again on the same or different mobile device, the script file associated with the service request is retrieved and provided to the mobile device, which executes the script file to automatically brings up a series of operation/display events to fulfill the service request. Thus, a user of the mobile device does not need to manually navigate through the sequence of operation/display events again in order to fulfill the service request.
    Type: Application
    Filed: December 3, 2018
    Publication date: April 4, 2019
    Inventor: Xiaoyun Wu
  • Transgenic Plants with Enhanced Traits
    Publication number: 20190023753
    Abstract: This disclosure provides plants having enhanced traits such as increased yield, increased nitrogen use efficiency and increased water use efficiency; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with the composition or with enhanced traits.
    Type: Application
    Filed: March 26, 2018
    Publication date: January 24, 2019
    Inventors: Mark S. Abad, Paul S. Chomet, Dhanalakshmi Ramachandra, Tyamagondlu V. Venkatesh, Xiaoyun Wu
  • Method and apparatus for automatic processing of service requests on an electronic device
    Patent number: 10146560
    Abstract: Embodiments of the present application provides methods and apparatus capable of recording operation/display events on a mobile device used to fulfill a service request entered via a user interface of the mobile device. A recorded sequence of operation/display events is used to build a script file, which is associated with the service request. When the same or similar service request is received again, the script file associated with the service request is retrieved for execution by the mobile device to automatically brings up a series of operation/display events so that a user of the mobile device does not need to manually navigate through the sequence of operation/display events again in order to fulfill the service request.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: December 4, 2018
    Inventor: Xiaoyun Wu
  • TRANSGENIC PLANTS WITH ENHANCED AGRONOMIC TRAITS
    Publication number: 20180237793
    Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced trait.
    Type: Application
    Filed: November 30, 2017
    Publication date: August 23, 2018
    Applicant: Monsanto Technology LLC
    Inventors: Eric D. Aasen, Mark Scott Abad, Edwards Allen, Thandoni Rao Ambika, Veena S. Anil, Alice Clara Augustine, Stephanie L. Back, Pranesh Badami, Amarjit Basra, Kraig L. Brustad, Molian Deng, Todd Dezwaan, Charles Dietrich, Stephen M. Duff, Karen K. Gabbert, Steve He, Bill L. Hendrix, Hongwu Jia, Vidya Kammaradi Ramanath Bhat, Balasulojini Karunanandaa, Kevin R. Kosola, Kempagangaiah Krishnamurthy, Ganesh Kumar, Saritha V. Kuriakose, Shantala Lakkanna, Mark E. Leibman, Linda Lutfiyya, Savitha Madappa, Sivalinganna Manjunath, Robert J. Meister, Bellur Narasimha Prasad, Sasha Preuss, Qungang Qi, Dhanalakshmi Ramachandra, Aniruddha Raychaudhuri, S. Sangeetha, Scott Saracco, Chitresh Sharma, Vijay K. Sharma, Monnanda S. Rajani, Padmini Sudarshana, Rebecca L. Thompson-Mize, Srikanth Venkatachalayya, Tyamagondlu V. Venkatesh, Huai Wang, Jingrui Wu, Xiaoyun Wu, Xiaofeng Sean Yang, Qin Zeng, Jianmin Zhao
  • COMPOSITIONS AND METHODS FOR CANCER EXPRESSING PDE3A OR SLFN12
    Publication number: 20180235961
    Abstract: The present invention features improved methods of identifying patients having cancer (e.g., melanoma, adenocarcinoma, lung, cervical, liver or breast cancer) using biomarkers (e.g., PDE3A, SLFN12) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., DNMDP, zardaverine, and anagrelide).
    Type: Application
    Filed: August 12, 2016
    Publication date: August 23, 2018
    Applicants: The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc., Bayer Pharma AG
    Inventors: Luc De Waal, Matthew Meyerson, Heidi Greulich, Monica Schenone, Alex Burgin, Xiaoyun Wu, Ulrike Sack
  • Transgenic Plants with Enhanced Traits
    Publication number: 20180215798
    Abstract: This disclosure provides plants having enhanced traits such as increased yield, increased nitrogen use efficiency and increased water use efficiency; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with the composition or with enhanced traits.
    Type: Application
    Filed: March 26, 2018
    Publication date: August 2, 2018
    Inventors: Mark S. Abad, Paul S. Chomet, Dhanalakshmi Ramachandra, Tyamagondlu V. Venkatesh, Xiaoyun Wu
  • Method and Apparatus for Automatic Processing of Service Requests on an Electronic Device
    Publication number: 20180095807
    Abstract: Embodiments of the present application provides methods and apparatus capable of recording operation/display events on a mobile device used to fulfill a service request. A recorded sequence operation/display events is used to build a script file, which is associated with the service request. When the same or similar service request is received again, the script file associated with the service request is retrieved and the mobile device automatically brings up a series of operation/display events according to the script file so that a user of the mobile device does not need to manually navigate through the sequence of operation/display events again in order to fulfill the service request.
    Type: Application
    Filed: January 4, 2017
    Publication date: April 5, 2018
    Inventor: Xiaoyun Wu
  • METHOD AND APPARATUS FOR AUTOMATIC PROCESSING OF SERVICE REQUESTS ON AN ELECTRONIC DEVICE
    Publication number: 20180095772
    Abstract: Embodiments of the present application provides methods and apparatus capable of recording operation/display events on a mobile device used to fulfill a service request entered via a user interface of the mobile device. A recorded sequence of operation/display events is used to build a script file, which is associated with the service request. When the same or similar service request is received again, the script file associated with the service request is retrieved for execution by the mobile device to automatically brings up a series of operation/display events so that a user of the mobile device does not need to manually navigate through the sequence of operation/display events again in order to fulfill the service request.
    Type: Application
    Filed: September 29, 2017
    Publication date: April 5, 2018
    Inventor: Xiaoyun Wu
  • Transgenic Plants With Enhanced Traits
    Publication number: 20170369894
    Abstract: This disclosure provides recombinant DNA constructs and transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Application
    Filed: December 2, 2015
    Publication date: December 28, 2017
    Inventors: Mark S. Abad, Erin Bell, Paul S. Chomet, Todd DeZwaan, Stephen Duff, Barry S. Goldman, Hongwu Jia, Lloyd Jones, Balasulojini Karunanandaa, Saritha V. Kuriakose, Linda L. Lutfiyya, Savitha Madappa, Zoe P. McKiness, Donald E. Nelson, Sasha Preuss, Monnanda S. Rajani, Dhanalakshmi Ramachandra, Aniruddha Raychaudhuri, Daniel P. Schachtman, Steven H. Schwartz, Char Shobha, Matthew M. Tanzer, Tyamagondlu V. Venkatesh, Huai Wang, Xiaoyun Wu
  • Transgenic Plants with Enhanced Traits
    Publication number: 20170233755
    Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Application
    Filed: April 28, 2017
    Publication date: August 17, 2017
    Applicant: Monsanto Technology LLC
    Inventors: Mark Scott ABAD, Pranesh BADAMI, Amarjit BASRA, Erin BELL, Christopher P. BONIN, Paolo CASTIGLIONI, R. Eric CERNY, Jaishree M. CHITTOOR, Paul CHOMET, Todd DEZWAAN, Stephen DUFF, Michael D. EDGERTON, Barry S. GOLDMAN, Balasulojini KARUNANANDAA, Kempagangaiah KRISHNAMURTHY, Ping LI, Adrian A. LUND, Linda LUTFIYYA, Thomas M. MALVAR, Donald E. NELSON, Monnanda S. RAJANI, Dhanalakshmi RAMACHANDRA, Thomas G. RUFF, Sara SALVADOR, S. SANGEETHA, Char SHOBHA, Jeffrey M. STAUB, Virginia URSIN, Tyamagondlu V. VENKATESH, Kammaradi R. VIDYA, Xiaoyun WU, Sean YANG, Jianmin ZHAO