Patents by Inventor Zhong Zheng
Zhong Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240156896Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.Type: ApplicationFiled: June 1, 2023Publication date: May 16, 2024Inventors: Michelle Denise Hoarty, Ketki Ashok Dhamnaskar, Daniel Elbaum, Kristopher Josephson, Kelley Cronin Larson, Zhong Ma, Nathan Ezekiel Nims, Alonso Ricardo, Kathleen Seyb, Guo-Qing Tang, Douglas A. Treco, Zhaolin Wang, Ping Ye, Hong Zheng, Sarah Jacqueline Perlmutter
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Patent number: 11965040Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.Type: GrantFiled: April 21, 2021Date of Patent: April 23, 2024Assignee: RA PHARMACEUTICALS, INC.Inventors: Michelle Denise Hoarty, Ketki Ashok Dhamnaskar, Daniel Elbaum, Kristopher Josephson, Kelley Cronin Larson, Zhong Ma, Nathan Ezekiel Nims, Alonso Ricardo, Kathleen Seyb, Guo-Qing Tang, Douglas A. Treco, Zhaolin Wang, Ping Ye, Hong Zheng, Sarah Jacqueline Perlmutter, Robert Paul Hammer
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Patent number: 11958681Abstract: The present invention relates to a ventilating and blanking device for a coal storage Eurosilo. The ventilating and blanking device includes a top blanking pipe, an axial flow fan and a baffle door, the top blanking pipe including a first pipeline and a second pipeline, an air supply pipe is connected to a side wall of the second pipeline, and the baffle door is connected to a driving mechanism; during blanking, the driving mechanism drives the baffle door so as to make the baffle door close the air supply pipe and the axial flow fan is shut off; and during ventilation, the driving mechanism drives the baffle door so as to make the baffle door close the first pipeline, and the axial flow fan is turned on. Compared with the prior art, the present invention has the advantages of ventilation efficiency, good ventilation effect, etc.Type: GrantFiled: May 10, 2021Date of Patent: April 16, 2024Assignees: HUANENG POWER INTERNATIONAL, INC., SHANGHAI SHIDONGKOU FIRST POWER PLANTInventors: Zhong Ni, Zhiwei Sang, Zhongming Huang, Xin Hu, Pengxia Ni, Ping Zhu, Qinghan Zheng, Runhan Liu, Xiao Zhang, Jinxin Yu, Haifeng Guan, Jialei Deng
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Patent number: 11918713Abstract: The present disclosure provides a high-temperature negative-pressure air exchange sterilizer and a sterilization method thereof. An air inlet is disposed at a bottom of a waterproof shell of the sterilizer, and an inlet filter is installed at the air inlet. Air entering from the air inlet is divided into two paths at a check valve. One path is connected with a negative-pressure fan through a pipeline B, and the other path is communicated with an air outlet through a pipeline A. A plurality of heating rods and temperature sensors are disposed in the pipeline A. The pipeline A is zigzag disposed at an upper part of the waterproof shell, and a thermal insulation material is disposed outside a zigzag part. A butterfly valve and an outlet filter screen are sequentially disposed at the air outlet in an air exhaust direction. The problem that viruses exhaled by breathing of an infected person are mixed in aerosol, so that a person in close contact with the infected person is likely to be infected is solved.Type: GrantFiled: May 31, 2021Date of Patent: March 5, 2024Assignee: HARBIN INSTITUTE OF TECHNOLOGYInventors: Zongquan Deng, Qiquan Quan, Dewei Tang, Rongqiang Liu, Zhong Zheng, Xiao Li
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Publication number: 20230002738Abstract: The present invention provides a method of treating a disorder using a fibromodulin (FMOD) reprogrammed (FReP) cell. The method comprises administering locally to a human being the FReP cell to a site in need thereof of the human being.Type: ApplicationFiled: February 24, 2022Publication date: January 5, 2023Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
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Patent number: 11520589Abstract: The invention discloses a data structure-aware prefetching method and device on a graphics processing unit. The method comprises the steps of acquiring information for a memory access request in which a monitoring processor checks a graph data structure and read data, using a data structure access mode defined by a breadth first search and graph data structure information to generate four corresponding vector prefetching requests and store into a prefetching request queue. The device comprises a data prefetching unit distributed into each processing unit, each data prefetching unit is respectively connected with an memory access monitor, a response FIFO and a primary cache of a load/store unit, and comprises an address space classifier, a runtime information table, prefetching request generation units and the prefetching request queue.Type: GrantFiled: April 28, 2019Date of Patent: December 6, 2022Assignee: NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGYInventors: Libo Huang, Hui Guo, Zhong Zheng, Zhiying Wang, Wei Guo, Guoqing Lei, Junhui Wang, Bingcai Sui, Caixia Sun, Yongwen Wang
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Patent number: 11504812Abstract: A method for making an infrared light absorber is provided, and the method includes following steps: providing a first carbon nanotube array on a substrate; truncating the carbon nanotube array by irradiating a top surface of the carbon nanotube array by a laser beam in two directions, the top surface being away from the substrate, wherein the two directions being at an angle, the angle is in a range of 30 degrees to 90 degrees.Type: GrantFiled: December 9, 2019Date of Patent: November 22, 2022Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Ying-Cheng Wang, Zhong-Zheng Huang, Yuan-Hao Jin, Qun-Qing Li, Shou-Shan Fan
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Publication number: 20220257071Abstract: A wet-dry vacuum cleaner device comprising: a housing; a motor-fan assembly mounted in the housing and arranged to generate an air flow between a dirty air inlet and a clean air outlet; a tank arranged to capture liquid entrained in the dirty air flow, the tank comprising a tank inlet in fluid communication with the dirty air inlet and a tank outlet in fluid communication with the motor fan assembly; wherein the tank outlet is in fluid communication with a liquid trap mounted inside the tank arranged to capture liquid entrained in the air flow exiting the tank.Type: ApplicationFiled: May 3, 2022Publication date: August 18, 2022Inventors: Pei Zhong Zheng, Jiang Jian Hui, Ren Bao Jiang, Fei Fei Yang, Hong Xi Wang
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Patent number: 11261432Abstract: The present invention provides a method of treating a disorder using a fibromodulin (FMOD) reprogrammed (FReP) cell. The method comprises administering locally to a human being the FReP cell to a site in need thereof of the human being.Type: GrantFiled: December 19, 2016Date of Patent: March 1, 2022Assignee: The Regents of the University of CaliforniaInventors: B. Chia Soo, Kang Ting, Zhong Zheng
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Patent number: 11255731Abstract: An infrared detector is provided, and the infrared detector includes: a thermoelectric element; an infrared light absorber, located on and in contact with the thermoelectric element, and configured to absorb infrared light and convert infrared light into heat; an electrical signal detector, electrically connected to the thermoelectric element and configured to detect a change in electrical performance of the thermoelectric element; wherein the infrared light absorber includes a carbon nanotube array, the carbon nanotube array includes a plurality of carbon nanotubes, a height of the plurality of carbon nanotubes are substantially the same, and the plurality of carbon nanotubes are perpendicular to the thermoelectric element.Type: GrantFiled: December 9, 2019Date of Patent: February 22, 2022Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Ying-Cheng Wang, Zhong-Zheng Huang, Yuan-Hao Jin, Qun-Qing Li, Shou-Shan Fan
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Publication number: 20210401937Abstract: Embodiments of the present invention provide a method treating cartilage arthritis in a subject in need thereof, which method comprising administering an effective amount of NELL-1 protein or peptide to the subject to ameliorate or treat at least an osteoinflammatory cartilage condition in the subject. The present invention also provides a composition and method therefor.Type: ApplicationFiled: October 31, 2019Publication date: December 30, 2021Applicant: The Regents of the University of CaliforniaInventors: B. Chia SOO, Kang TING, Zhong ZHENG, Chenshuang LI
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Publication number: 20210290813Abstract: The present disclosure provides a high-temperature negative-pressure air exchange sterilizer and a sterilization method thereof. An air inlet is disposed at a bottom of a waterproof shell of the sterilizer, and an inlet filter is installed at the air inlet. Air entering from the air inlet is divided into two paths at a check valve. One path is connected with a negative-pressure fan through a pipeline B, and the other path is communicated with an air outlet through a pipeline A. A plurality of heating rods and temperature sensors are disposed in the pipeline A. The pipeline A is zigzag disposed at an upper part of the waterproof shell, and a thermal insulation material is disposed outside a zigzag part. A butterfly valve and an outlet filter screen are sequentially disposed at the air outlet in an air exhaust direction. The problem that viruses exhaled by breathing of an infected person are mixed in aerosol, so that a person in close contact with the infected person is likely to be infected is solved.Type: ApplicationFiled: May 31, 2021Publication date: September 23, 2021Inventors: Zongquan Deng, Qiquan Quan, Dewei Tang, Rongqiang Liu, Zhong Zheng, Xiao Li
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Patent number: 11033605Abstract: Provided herein is a method of promoting tissue repair, comprising delivering to a subject a therapeutically effective amount of fibromodulin (FMOD), FMOD polypeptide, FMOD peptide, or a variant or derivative or analog thereof according to a dosing regimen to cause an injured tissue to form a repaired tissue having an improved condition provided that the improved condition does not include improved condition of scar of skin.Type: GrantFiled: June 8, 2017Date of Patent: June 15, 2021Assignee: The Regents of the University of CaliforniaInventors: B. Chia Soo, Kang Ting, Zhong Zheng
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Publication number: 20210128791Abstract: The application discloses an implantable device, comprising a galvanic redox system formed on a body substrate of the implantable device. The implantable device has a non-zero surface potential when it is deployed. The galvanic redox system comprises a first metal site and a second metal site, the first metal site comprising a first metal having a first metal electrode potential (FMEP) and the second metal site comprising a second metal having a second metal electrode potential (SMEP), which FMEP being lower than SMEP and SMEP being substantially different such that the implantable device is galvanized when it is deployed. Methods of making and using the implantabe device are also disclosed.Type: ApplicationFiled: October 19, 2020Publication date: May 6, 2021Inventors: B. Chia Soo, Kang Ting, Zhong Zheng, Benjamin Wu, Yulong Zhang
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Patent number: 10931148Abstract: A passive tag transponder circuit comprising a receive antenna, reflect antenna, and rectifier network. The receive antenna can be configured to receive an ambient RF signal having a frequency of fc, or, a backscattered RF signal having a frequency of 2fc. The reflect antenna can be configured to receive a rectified output signal from the rectifier network, the rectified output signal having a frequency of 2fc. The reflect antenna can be configured to send a backscattered signal at the frequency of 2fc. The rectifier network can be connected to receive an input corresponding to the ambient RF from the receive antenna and send the rectified output to the reflect antenna.Type: GrantFiled: April 23, 2018Date of Patent: February 23, 2021Assignee: Board of Regents, The University of Texas SystemInventors: Zygmunt Haas, Zhong Zheng
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Publication number: 20210004648Abstract: Computer vision systems and methods for localizing image forgery are provided. The system generates a constrained convolution via a plurality of learned rich filters. The system trains a convolutional neural network with the constrained convolution and a plurality of images of a dataset to learn a low level representation of each image among the plurality of images. The low level representation is indicative of a statistical signature of at least one source camera model of each image. The system can determine a splicing manipulation localization by the trained convolutional neural network.Type: ApplicationFiled: July 2, 2020Publication date: January 7, 2021Applicant: Insurance Services Office, Inc.Inventors: Aurobrata Ghosh, Zhong Zheng, Terrance E. Boult, Maneesh Kumar Singh
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Patent number: 10846082Abstract: A comment quality system for improving comments for source code includes a processor and memory. An operating system is executed by the processor and memory. A comment quality application, executed by the processor and memory, is configured to receive data relating to a number of source code comments that are associated with source code developed in a code developer application, generate a desired number of comments based on an estimated quality of comments for a code developer and a number of reviewers of the source code, and send feedback to the code developer application based on the desired number of comments for the source code and the number of source code comments.Type: GrantFiled: September 8, 2016Date of Patent: November 24, 2020Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Liya Fan, Haibo Lin, Zhong Zheng
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Publication number: 20200364053Abstract: The invention discloses a data structure-aware prefetching method and device on a graphics processing unit. The method comprises the steps of acquiring information for a memory access request in which a monitoring processor checks a graph data structure and read data, using a data structure access mode defined by a breadth first search and graph data structure information to generate four corresponding vector prefetching requests and store into a prefetching request queue. The device comprises a data prefetching unit distributed into each processing unit, each data prefetching unit is respectively connected with an memory access monitor, a response FIFO and a primary cache of a load/store unit, and comprises an address space classifier, a runtime information table, prefetching request generation units and the prefetching request queue.Type: ApplicationFiled: April 28, 2019Publication date: November 19, 2020Applicant: NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGYInventors: Libo HUANG, Hui GUO, Zhong ZHENG, Zhiying WANG, Wei GUO, Guoqing LEI, Junhui WANG, Bingcai SUI, Caixia SUN, Yongwen WANG
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Publication number: 20200345811Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.Type: ApplicationFiled: July 14, 2020Publication date: November 5, 2020Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
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Publication number: 20200270311Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: May 8, 2020Publication date: August 27, 2020Inventors: Richard E. Lee, Ying Zhao, Elizabeth Griffith, Zhong Zheng, Aman P. Singh