Patents by Inventor Zhong Zheng

Zhong Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170312393
    Abstract: Provided herein is a wound-healing-enhancing device that comprises a body structure and a wound-healing-enhancing agent in a wound-healing-enhancing effective amount. Methods of fabricating and using the device are also provided.
    Type: Application
    Filed: June 8, 2017
    Publication date: November 2, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG, Benjamin M. WU, Yulong ZHANG
  • Publication number: 20170266256
    Abstract: Provided herein is a method of promoting tissue repair, comprising delivering to a subject a therapeutically effective amount of fibromodulin (FMOD), FMOD polypeptide, FMOD peptide, or a variant or derivative or analog thereof according to a dosing regimen to cause an injured tissue to form a repaired tissue having an improved condition provided that the improved condition does not include improved condition of scar of skin.
    Type: Application
    Filed: June 8, 2017
    Publication date: September 21, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG
  • Patent number: 9744214
    Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: August 29, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Publication number: 20170212947
    Abstract: The upgrading of a relational database on multiple of machines (e.g., a service) that perform data operations via a set of one or more stored procedures. The upgrade occurs without changing the functionality of the set of one or more stored procedures. Accordingly, even if the machine itself is not upgraded, the machines can still interface with the database via the set of one or more stored procedures. The upgrade of the relational database occurs by adding occur by adding new table(s) to the relational database, and thereafter adding new stored procedures to the stored procedure store, the new stored procedures referencing parameters of the new tables. Since the machines that interface with the relational database can still operate on the upgraded database using the old stored procedures, each machine may then be upgraded in an orderly manner to interface with the new stored procedures.
    Type: Application
    Filed: January 21, 2016
    Publication date: July 27, 2017
    Inventors: Zhong Zheng, Haibo Lin, Silan Wang
  • Publication number: 20170182207
    Abstract: Provided herein is a biocompatible device comprising a body structure and a wound-healing-enhancing agent in a wound-healing-enhancing effective amount, wherein the wound-healing-enhancing agent is embedded within the body structure or coated on the body structure. An example of the device is a surgical suture. Methods of fabricating and using the device are also provided.
    Type: Application
    Filed: December 9, 2016
    Publication date: June 29, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG, Benjamin M. WU, Yulong ZHANG
  • Publication number: 20170159022
    Abstract: The present invention provides a method of treating a disorder using a fibromodulin (FMOD) reprogrammed (FReP) cell.
    Type: Application
    Filed: December 19, 2016
    Publication date: June 8, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong Zheng
  • Publication number: 20170159021
    Abstract: The present invention provides a method of forming a fibromodulin (FMOD) reprogrammed (FReP) cell. This application includes the sequence listing which is identical to the sequence information in the last filed computer readable form (CFR) on Aug. 1, 2014 in U.S. application Ser. No. 14/353,284, filed Apr. 21, 2014, entitled “2014-08-01 384578-991391 ST25.tax” and is hereby incorporated by reference in its entirety.
    Type: Application
    Filed: December 19, 2016
    Publication date: June 8, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong Zheng
  • Patent number: 9549954
    Abstract: The present invention provides a fibromodulin (FMOD) reprogrammed (FReP) cell and a method of making therefor, a culture medium therefor, and a supernatant thereof, and methods of making and using these.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: January 24, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Patent number: 9545712
    Abstract: A sander may include a housing, a motor, a sanding platen, and a two-piece fan. The motor may be disposed within the housing and may include an output shaft. The sanding platen may be driven by the motor for movement relative to the housing. The fan may be driven by the motor and may include a first piece formed from a first material and a second piece formed from a second material. The first piece may include a disk-shaped body having first and second opposite sides. The first side may include a plurality of first blades extending therefrom. The second side may include a plurality of second blades extending therefrom and a recess formed therein. The second piece may be received in the recess and may include a counterweight boss formed thereon.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: January 17, 2017
    Assignee: BLACK & DEKCER INC.
    Inventors: Brent A. Kuehne, Earl Kelican, Jr., Xin Lei Wang, Feng Chen, Pei Zhong Zheng
  • Publication number: 20160347762
    Abstract: The invention relates to aryl substituted aminomethyl spectinomycin analogs, derivatives thereof, and related compounds, which are useful as anti-bacterial agents; methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating anti-bacterial infections using the compounds and compositions.
    Type: Application
    Filed: September 29, 2014
    Publication date: December 1, 2016
    Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
    Inventors: Richard E. Lee, Samanthi L. Waidyarachchi, David F. Bruhn, Jiuyu Liu, Zhong Zheng, Jason W. Rosch
  • Publication number: 20160304573
    Abstract: Disclosed herein is a method of making a fibromodulin peptide (FMOD-P), compositions thereof, and methods of using the FMOD-P and the compositions thereof for treating or ameliorating a condition.
    Type: Application
    Filed: June 28, 2016
    Publication date: October 20, 2016
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Patent number: 9409963
    Abstract: Embodiments of the present invention provide a fibromodulin (FMOD) peptide (FMOD-P), a composition and a formulation comprising a FMOD-P, option-ally with a TGF-? isoform, or comprising FMOD with a TGF-? isoform. The present invention also provides methods of making and using the FMOD-P, composition, or formulation.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: August 9, 2016
    Assignee: The Regents of the University of California
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Publication number: 20160200770
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: August 30, 2014
    Publication date: July 14, 2016
    Inventors: Richard E. Lee, Ying Zhao, Elizabeth Griffith, Zhong Zheng, Aman P. Singh
  • Publication number: 20140369971
    Abstract: The present invention provides a fibromodulin (FMOD) reprogrammed (FReP) cell and a method of making therefor, a culture medium therefor, and a supernatant thereof, and methods of making and using these.
    Type: Application
    Filed: October 22, 2012
    Publication date: December 18, 2014
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Publication number: 20140287018
    Abstract: Implant-associated bacterial infections are one of the most serious complications in orthopedic surgery. Treatment of these infections often requires multiple operations, device removal, long-term systemic antibiotics, and extended rehabilitation, and is frequently ineffective, leading to worse clinical outcomes and increased financial costs. Silver nanoparticle/poly(DL-lactic-co-glycolic acid) (PLGA)-coated stainless steel alloy (SNPSA) was evaluated as a potential antimicrobial implant material. It was found that SNPSA exhibited strong antibacterial activity in vitro and ex vivo, and promoted MC3T3-E1 pre-osteoblasts proliferation and maturation in vitro. Furthermore, SNPSA implants induced osteogenesis while suppressing bacterial survival in contaminated rat femoral canals. The results indicate that SNPSA has simultaneous antimicrobial and osteoinductive properties that make it a promising therapeutic material in orthopedic surgery.
    Type: Application
    Filed: October 19, 2012
    Publication date: September 25, 2014
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Publication number: 20140227258
    Abstract: The invention provides therapeutic anti-c-met antibodies, and compositions comprising and methods of using these antibodies.
    Type: Application
    Filed: March 14, 2014
    Publication date: August 14, 2014
    Applicant: Genentech, Inc.
    Inventors: Mark S. Dennis, Karen Billeci, Judy Young, Zhong Zheng
  • Publication number: 20140105939
    Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof
    Type: Application
    Filed: December 13, 2013
    Publication date: April 17, 2014
    Applicant: The Regents of the University of California
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG
  • Patent number: 8689915
    Abstract: The present invention provides a heat dissipating system for an electric vehicle drive controller. The heat dissipating system for electric vehicle drive controller includes: high power MOS transistors for controlling magnitude of power supplied to an electric vehicle drive motor and for switching current direction, and a radiator connected to bodies of the MOS transistors, the radiator being made of aluminum alloy material, and a surface of the radiator being plated with a metallic nickel layer. Compared with existing electric vehicle drive controller, the electric vehicle drive controller of the present invention has advantages of low operating temperature, high reliability and long service life.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: April 8, 2014
    Assignee: Liuzhou Wuling Motors Co., Ltd.
    Inventors: Yanzhang Ye, Ben Cai, Rijun Huang, Libin Wei, Zhong Zheng
  • Patent number: 8369941
    Abstract: A method for producing a computationally efficient system that reduces the number of iterations required to generate a conductivity image pattern of a subsurface object, and its attendant conductivity distribution, through a solution to the system of field equations that simultaneously satisfies all of the boundary conditions and conserves internal current flux densities.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: February 5, 2013
    Inventors: Alvin Wexler, Rajen Manicon Murugan, Zhong Zheng, Misty O'Connor
  • Publication number: 20120171253
    Abstract: Embodiments of the present invention provide a fibromodulin (FMOD) peptide (FMOD-P), a composition and a formulation comprising a FMOD-P, optionally with a TGF-? isoform, or comprising FMOD with a TGF-? isoform. The present invention also provides methods of making and using the FMOD-P, composition, or formulation.
    Type: Application
    Filed: May 26, 2010
    Publication date: July 5, 2012
    Applicant: The Regents of the University of California
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng