Abstract: One solid preparation of the present invention mainly includes silicon fine particles, and has a capability of generating hydrogen. In addition, one specific example of the solid preparation mainly includes silicon fine particles having a crystallite diameter principally of 1 nm or more and 100 nm or less, and exhibits a capability of generating hydrogen in an amount of 3 ml/g or more when brought into contact with a water-containing liquid having a pH value of 7 or more. In this solid preparation, hydrogen is generated when the silicon fine particles are brought into contact with a water-containing liquid having a pH value of 7 or more. Therefore, taking advantage of the characteristics of the solid preparation, generation of hydrogen is promoted in, for example, a gastrointestinal tract where the pH value is 7 or more due to secretion of pancreatic fluid after passage through the stomach after oral ingestion.

Abstract: Disclosed is a device and method for diffusing a therapeutic specific to a user's emotional/mental state (EMS), comprising the steps of: selecting (or assessing) at least one EMS, said selected (or assessed) EMS indicating at least one of an emotion, mental, and/or physical state of the user; and activating the ultrasonic membrane of the at least single reservoir (optionally, a plurality of reservoirs) housing the mist specific to the selected/assessed EMS, wherein said activation results in a vibration of the membrane causing an ultra-sonic frequency resulting in the atomization and diffusion of the prescribed mist based on the user-selected (or assessed) EMS.

Abstract: An aerosol delivery device including: control circuitry for controlling an operating mode of the device; a motion sensor arranged to detect motion of the device and to output corresponding motion detection signals to the control circuitry; and an airflow sensor arranged to detect a flow of air in the device and to output corresponding airflow detection signals to the control circuitry; wherein the control circuitry is configured to determine from the motion detection signals when there is a tapping event corresponding to the device being tapped by a user and to determine from the airflow detection signals when there is an airflow event, and wherein the control circuitry is configured to control the device to switch from a first operating mode to a second operating mode in response to the detection of a predefined sequence of events comprising at least one tapping event and at least one airflow event.

Abstract: A nebulization device having dual modules includes: a nebulization host machine; a three-way tube communicated with the nebulization host machine; and a controller connected to the nebulization host machine; the nebulization host machine further includes a side cover, a nozzle arranged on a lower side of the side cover, a liquid medicine bottle arranged on an upper side of the side cover and communicated with the nozzle, a nebulization sheet arranged on one side of the liquid medicine bottle and communicated with the nozzle, and a first plug-in interface arranged below the liquid medicine bottle; a bottom portion within an interior of the nozzle is provided with a partition plate that divides the interior of the nozzle into an upper nebulization chamber and a lower gas flow chamber.

Abstract: An in-line droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The in-line droplet delivery device includes a housing, a mouthpiece, a reservoir, an ejector mechanism, and at least one differential pressure sensor. The in-line droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The in-line droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range, e.g, less than about 5-6 ?m, so as to target the pulmonary system of the user. the droplet delivery device is configured in an in-line orientation in that the housing, its internal components, and various device components (e.g., the mouthpiece, air inlet flow element, etc.) are orientated in a substantially in-line or parallel configuration (e.g.

Abstract: A delivery device for and method of modulating a condition relating to social cognition and/or behaviour in a human subject using oxytocin, non-peptide agonists thereof and/or antagonists thereof, comprising: providing a nosepiece to a first nasal cavity of the subject; and providing a supply unit for administering less than 24 IU of oxytocin, non-peptide agonists thereof and/or antagonists thereof through the nosepiece to an upper region posterior of the nasal valve which is innervated by the trigeminal nerve.

Abstract: A fingerprint reader/power button system includes a base member defining base leg apertures extending into the base member. A spring member engages the base member to provide a spring force that is directed away from the base member. Spring legs on the spring member define respective spring leg apertures that are located adjacent respective base leg apertures. A support member engages the spring member and includes support legs that are configured to extend through the spring leg apertures and into the base leg apertures. A power actuator element connected to the support member is configured to engage a power actuator engagement element when an actuation force on the support member overcomes the spring force. A fingerprint reader connected to the support member is configured to read a fingerprint from a finger that engages a fingerprint reader surface on the fingerprint reader.

Abstract: A biomimetic system is provided for evaluating an effect of a test sample in vitro, and includes at least one organ chip, at least one medium container, a liquid pump, a nebulizer, a gas pump, and a chamber device. The liquid pump is provided to drive a liquid medium in the medium container to flow into a lower sub-channel of the organ chip and then to be discharged back into the medium container. The nebulizer is provided for atomizing a test solution including the test sample into an aerosol. The gas pump is provided to generate a pressurized gas which force the aerosol to flow out of a chamber of the chamber device and then to flow through an upper sub-channel of the organ chip.

Abstract: A liquid storage tank of an electronic vapor provision device includes one or more boundary walls defining an interior volume of the tank for accommodating source liquid to be vaporized in the electronic vapor provision device; and one or more baffles, each baffle protruding from an inner surface of the boundary wall into the interior volume to impede a flow of source liquid between portions of the interior volume between which the baffle is located. The tank may be included in an electronic vapor provision device or in a component for an electronic vapor provision device such as a cartomizer.

Abstract: According to an aspect, there is provided a training device for use in an inhaler, the training device comprising a body that is configured to be received at a first position in a housing of an inhaler, wherein the body comprises an interface arranged to connect to a canister interface in the housing of the inhaler; an electrical circuit configured to perform one or more functions; and a circuit triggering mechanism that comprises a switch for enabling the electrical circuit to perform the one or more functions when the switch is closed, wherein the circuit triggering mechanism is configured such that the switch is closed when the body is pressed from the first position towards the canister interface and into a second position in the housing of the inhaler.

Abstract: A nosepiece for delivering substance to a nasal cavity of a subject, the nosepiece comprising a body part which comprises a base portion which defines a flow passage therethrough, and a projection at a distal end of the base portion which at least in part provides a tip of the nosepiece and confers a rigidity in the sagittal direction, which enables the tip to open fleshy tissue at an upper region of the nasal valve and thereby expand an open area of the nasal valve, and a flexibility in a lateral direction, orthogonal to the sagittal plane, which facilitates insertion of the tip into the nasal valve.

Abstract: The accessory (110) for an inhaler (100) is adapted to be removably assembled on a casing (101) of the inhaler (100), and comprises: an acceleration sensor (112), an optical type proximity sensor (113), an electronic circuitry (114) electrically connected to the acceleration sensor (112) and to the proximity sensor (113); the electronic circuitry (114) in combination with the acceleration sensor (112) and the proximity sensor (113) is adapted to detect a drug administration process; the electronic circuitry (114) in combination with the acceleration sensor (112) is adapted to detect an inhalation flow inside said inhaler (100).

Abstract: The present disclosure relates to an aerosol delivery device and related methods and computer program products for controlling an aerosol delivery device based on input characteristics. For example, a method may include an aerosol delivery device determining a characteristic of a user input to the aerosol delivery device. The method may further include the aerosol delivery device determining a control function having a defined association with the characteristic. The method may additionally include the aerosol delivery device performing the control function in response to the user input.

Abstract: A pharmaceutical composition is described. The composition may include a drug component and a propellant component. The drug component comprises at least one pharmaceutically acceptable salt of glycopyrrolate and at least one long acting beta-2-agonist (LABA) selected from formoterol and the pharmaceutically acceptable salts thereof. At least 90 weight % of the propellant component is 1,1-difluoroethane (HFA-152a).

Abstract: The current pandemic due to Covid-19 stresses the importance of effectively treating highly contagious and deadly infections. The described medical device is meant to help the medical community by enabling them to treat patients more effectively. The delivery mechanism focuses on the mucous membrane. It is noninvasive and easy to use by patients directly. The device is hand-held, with incorporated germicidal UVC lights. It has two chambers connected by an internal application tip. The tip connects to a removable container which can be used with the prescribed treatment/therapy, vaccine, or viral testing fluid/reagent, as needed. Due to its versatility, non-invasive nature and germicidal properties, this device supports rapid response to infectious diseases, such as COVID-19. It may also further promote the development and use of different inoculation and drug techniques and delivery systems by enabling easy administration, via the mucous membrane.

Abstract: Described herein are various embodiments of an oxygen concentrator system and method of delivering oxygen enriched gas to a user. In some embodiments, oxygen concentrator system includes one or more components that improve the efficiency of oxygen enriched gas delivery during operation of the oxygen concentrator system.

Abstract: An aerosol generating device includes an aerosol generator and a plug. The aerosol generator includes a container and an atomizing module arranged in the container. The container has a liquid chamber, an aerosol chamber, and an insertion slot defining an insertion direction. The liquid chamber and the aerosol chamber are respectively arranged at two opposite sides of the atomizing module, and are in spatial communication with each other through the atomizing module. The atomizing module includes two electrode regions having the same polarity and being electrically connected to each other. The plug is detachably inserted into the insertion slot of the container along the insertion direction, and a conductive terminal of the plug contacts the two electrode regions.

Abstract: An inhaler or add-on device for an inhaler for dispensing a medicament to be inhaled. The inhaler or add-on device has a housing (H) with an air inlet (A_I), and an air outlet (A_O) for outputting air to be inhaled by a user. The housing (H) defines a flow path (FP) between the air inlet (A_I) and air outlet (A_O), and a passive acoustic element (PAE) is arranged in this flow path (FP) inside the housing (H). The passive acoustic element (PAE) has a structure having one or more structured gaps arranged to be passed by an air flow and it is dimensioned such that air flow passing it will generate sound (S) with pre-determined characteristics depending on the air flow speed. This allows acoustic monitoring of air flow passing the first passive acoustic element (PAE) external to the housing (H) by capturing and processing sound generated.

Abstract: A switch control circuit and method for an electronic cigarette and the electronic cigarette are disclosed, the circuit includes a sensing circuit including a first sensor, a second sensor and a heating part disposed between the first sensor and the second sensor for conveying heat to the first sensor and the second sensor; the first sensor is for detecting a first voltage generated by change of temperatures when an air flow is flowing over the first sensor; the second sensor is configured for detecting a second voltage generated by change of temperatures when the air flow is flowing over the second sensor; and a controller coupled with a sensing circuit and stores a preset voltage threshold for receiving the first voltage and the second voltage, comparing a voltage differential of the first voltage and the second voltage with the preset voltage threshold, and outputting corresponding action signals based on comparison.

Abstract: An inhaler includes a mouthpiece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalation.

Abstract: A nebulizer for a fluid, includes a container containing the fluid; a housing part which can be detached from the nebulizer for replacing the container; an inner part; a retaining element connected with and not detachable from the inner part, where the housing part is releasable fixed to the inner part by the retaining element; a delivery mechanism for dispensing the fluid; a manually depressible actuator member, which is a separate part from the retaining element and acts on the retaining element, and wherein the actuator member is depressed to elastically deform or flex the retaining element to allow detachment of the housing part.

Abstract: A pharmaceutical composition is described. The composition may include a drug component and a propellant component. The drug component comprises at least one pharmaceutically acceptable salt of glycopyrrolate and at least one long acting beta-2-agonist (LABA) selected from formoterol and the pharmaceutically acceptable salts thereof. At least 90 weight % of the propellant component is 1,1-difluoroethane (HFA-152a).

Abstract: A tub is configured to contain a supply of water and is configured to be inserted into a chamber of a humidifier. The tub includes a tub base configured to contain the supply of water. The tub also includes a tub lid and a flow plate provided between the tub base and the tub lid. The flow plate includes a water level indicator configured to indicate a level of the supply of water in the tub base. In addition, the water level indicator includes a generally rectangular portion and a generally triangular portion.

Abstract: A battery unit is installed in a flavor inhaler with an atomizing unit that atomizes an aerosol-generating material according to a puffing action of inhaling air through an air passage leading from an air inlet to an air outlet. The battery unit includes a battery, an electronic component configured to control the atomizing unit, and a housing configured to accommodate the battery and the electronic component. The electronic component is located in a predetermined portion of the battery unit. The predetermined portion includes a water detection member configured to detect water that enters the predetermined portion.

Abstract: A connector is used to connect a gases supply to a user. The user can be fitted with an interface, such as a cannula, while the gases supply can include a conduit. The connector interfaces between the conduit and the interface. The connector has a female assembly and a male assembly that connect together, such as by push fit. The male assembly includes an inner portion sized and configured to mate with a first female connector and an outer portion sized and configured to alternatively mate with a second female connector.

Abstract: An electronic vaping device may be designed to enhance or facilitate its use. For example, the electronic vaping device may: allow a capability of the electronic vaping device to provide vapor to be altered (e.g., disabled, reduced, enabled, or increased) in some situations (e.g., to prevent unauthorized vaping by a child, teenager or other individual); be able to communicate with an external communication device (e.g., a smartphone, a computer, etc.) to convey a notification of potential unauthorized use of the electronic vaping device (e.g., by a child, teenager or other unauthorized user); implement a physical deterrent to its unauthorized use; be able to visually convey information (e.g., advertisements, notifications, etc.); and/or be able to capture images and/or sounds (e.g., record pictures and/or video, speech, music, etc.).

Abstract: A method and formulation for delivering a motion sickness antidote in a vaporized state using low temperatures to vaporize the formulation. The formulation contains an inert non-reactive compound that lowers the heat of vaporization of the formulation, and the motion sickness antidote. The formulation may optionally contain glycerin, alcohol, and/or water. Examples of inert non-reactive compounds that can sufficiently lower the heat of vaporization of the formulation include propylene glycol, vegetable glycerin and polysorbate. The formulation can be vaporized using a hand-held low temperature vaporizer or atomizer.

Abstract: A modularized respiratory treatment apparatus provides various respiratory pressure treatments. The apparatus may be formed by discrete connectable modules such as a flow generator module, alarm module and/or humidifier module. Each module may include its own external casing or housing to independently retain or enclose the respective components that serve the function of the module. Different modules may be adapted with different components and functionalities and may be readily coupled using standardized gas and electrical connection configurations that have flow and communication paths that extend through the modules. When coupled, operation of the respiratory treatment apparatus may be controlled by detection of different modules, such as the alarm module that generates visual and/or audible alarms based on detected conditions, so as to selectively enable or disable different respiratory treatments.

Abstract: An aerosol-generating system may include a liquid storage portion configured to hold liquid aerosol-forming substrate, a vaporizer including a heating element with an internal passage at least partially defined by a surface of the heating element, and a micro pump configured to deliver liquid aerosol-forming substrate from the liquid storage portion to the internal passage of the heating element, such that the vaporizer is configured to heat the delivered liquid aerosol-forming substrate at the internal passage to a temperature sufficient to volatilize at least a part of the delivered liquid aerosol-forming substrate. The micro pump may be configured to deliver a particular amount of liquid aerosol-forming substrate to the internal passage based on the micro pump performing an individual pump cycle.

Abstract: A method includes receiving a scheduling request that identifies a medical consumable, accessing first document types that indicate how often medical consumables are to be ingested, identifying a frequency at which the first designated medical consumable is to be consumed based on the first document types, accessing second document types that indicate a pattern of personal activity behavior, identifying one or more temporal opportunity windows based on the second document types, determining one or more matches between the frequency at which the first designated medical consumable is to be consumed and the one or more temporal opportunity windows, creating an adherence schedule based on the one or more matches that indicates when reminders to ingest the first designated medical consumable are to be generated, and generating one or more of the reminders to ingest the first designated medical consumable on a mobile electronic device according to the adherence schedule.

Abstract: A unit dose capsule for use with a sonic generator includes a deformable membrane adapted to releasably engage the distal end of the elongate horn, a nozzle including at least one delivery opening; a nozzle including at least one delivery opening; and a reservoir containing a liquid composition disposed therebetween. When the unit dose capsule is engaged to the distal end of the elongate horn, the nozzle is disposed in an outwardly facing orientation, and the reservoir is in liquid communication with the at least one nozzle. The unit dose capsule can be included in a kit with a handheld misting device comprising a housing having a dispensing window arranged and configured to contain a sonic generator and a power source.

Abstract: A refill assembly configured to be removably coupled to a reusable assembly of a medicinal inhaler is disclosed and includes a patient port, a canister actuable by the reusable assembly to deliver a dose of medicament to the patient port, and a sleeve which is selectively actuable by a user independently of the reusable assembly so as to act on the canister to deliver a dose of medicament. The refill assembly further includes an override element which engages the sleeve, the override element being moveable from a first position in which the sleeve is retained in a first position by the override element and a second position in which the sleeve is permitted to move to a second position upon depression of the sleeve by a user to cause a dose of medicament to be delivered to the patient port.

Abstract: A device for delivering a compound to the olfactory region of the nasal cavity includes an actuator body and a tip configured to removably couple to the actuator body. The actuator body comprises a propellant channel in fluid communication with a propellant canister. The tip comprises a tip stem, a dip tube, a delivery channel, one or more puncture members, and an outlet orifice. The tip stem receives a compound container containing the compound and the compound container moves between a sealed state and an unsealed state. The one or more puncture members are each configured to puncture the compound container when the compound container is in the unsealed state. Propellant released from the canister travels through the propellant channel and into the punctured compound container, thereby contacting the compound and propelling the compound through the delivery channel and out the outlet orifice.

Abstract: A nano-pharmaceutical formulation, comprising zein nanoparticles, icariin (ICA) or a pharmaceutically acceptable salt thereof encapsulated within the zein nanoparticles, at least one solubilizer, wherein the at least one solubilizer comprises D-a-Tocopherol polyethylene glycol 1000 succinate (TPGS), and one or more pharmaceutical penetration enhancers is provided. Methods of enhancing libido by administering a composition as described herein is also provided.

Abstract: A method of using a fluid dispenser unit having a reservoir and a piston that slides in the reservoir. The unit includes an extractor head secured to the reservoir to suck fluid to be dispensed into the reservoir, and a spray head assembled on the extractor head to spray the fluid out from the reservoir. The method includes the steps of sucking a fluid to be dispensed into the reservoir through the extractor head; assembling the spray head on the extractor head; and spraying the fluid through the spray head. The step of sucking up a fluid to be dispensed includes a first step of extracting a fluid, such as a solvent, from an extraction reservoir, and a second step of mixing the fluid with a first substance, such as a powder or a lyophilisate, so as to form the fluid to be dispensed.

Abstract: A system may include an external device and an inhaler. The external device may include a processor, a communication circuit, and memory. The inhaler may include a mouthpiece, medicament, a mechanical dose counter, and an electronics module comprising a processor and a communication circuit. The electronics module may record a dosing event when the inhaler is actuated, such as when the mouthpiece cover is opened, and send a signal indicating the dosing event to the external device. The external device may receive a mechanical dose reading of the mechanical dose counter, determine an electronic dose reading based on the signal indicating the dosing event, determine that a discrepancy between the mechanical dose reading and the electronic dose reading exceeds a threshold, and notify the user of the discrepancy, for example, by providing a notification to the user by way of a mobile application residing on the external device.

Abstract: The invention relates to an aerosol delivery device (10) comprising an aerosol generator (3) for generating an aerosol in the aerosol delivery device (10), a sensor (5) configured to detect a use of the aerosol delivery device (10) for aerosol treatment, and a controller (7) configured to deactivate the aerosol generator (3) if no use of the aerosol delivery device (10) for aerosol treatment is detected by the sensor (5). Further, the invention relates to a method for operating an aerosol delivery device (10), comprising the steps of operating an aerosol generator (3) for generating an aerosol in the aerosol delivery device (10), detecting a use of the aerosol delivery device (10) for aerosol treatment by means of a sensor (5), and deactivating the aerosol generator (3) by means of a controller (7) if no use of the aerosol delivery device (10) for aerosol treatment is detected by the sensor (5).

Abstract: An electronic smoking article, a method of manufacturing an electronic smoking article, and a method of achieving a smoking experience without combusting tobacco are disclosed. The electronic smoking article includes an authenticated first section, which includes an aerosol generation unit having at least one heater; an authenticated second section, which includes a power supply operable to apply voltage to the at least one heater for heating a liquid in at least a portion of the aerosol generation unit to form an aerosol; and a conductive ink circuit embedded within the first and second sections, and wherein the power supply and the aerosol generation unit are electrically connected upon joining the first and second sections, and wherein each of the first and second sections has a portion of the conductive ink circuit.

Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

Abstract: A method of regulating pain in a patient includes operations of measuring a patient pain level, determining a dose of ethanol which does not trigger alcohol intolerance or intoxication, delivering the dose of ethanol to the patient by inhalation from an active mesh nebulizer at a repeated interval, measuring the pain level of the patient at a monitoring interval, and determining, based on the patient pain level, whether to adjust the ethanol dose. The dose of ethanol is delivered in the form of particles of nebulized liquid having a diameter ranging from about 0.5 ?m to about 5.0 ?m, which are rapidly absorbed into the bloodstream of a patient and delivered to the brain.

Abstract: A dry powder aerosol delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The dry powder aerosol delivery device includes a housing, a cartridge, and a dry powder dispersion mechanism, and at least one differential pressure sensor. The dry powder delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The dry powder aerosol delivery device is then actuated to generate a plume of particles having an average ejected particle diameter within the respirable size range, e.g., less than about 5-6 ?m, so as to target the pulmonary system of the user.

Abstract: An oscillating positive expiratory pressure device comprising a housing enclosing at least one chamber, a chamber inlet configured to receive exhaled air into the at least one chamber, and a chamber outlet configured to permit exhaled air to exit the at least one chamber. A channel is positioned in an exhalation flow path between the chamber inlet and the chamber outlet, with the channel being movably connected to a chamber of the at least one chamber. An air flow regulator is movable with respect to the channel between a first position, where the flow of air through the channel is restricted and a second position, where the flow of air through the channel is less restricted, the air flow regulator being configured to repeatedly move between the first position and the second position in response to a flow of exhaled air.

Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.

Abstract: An electronic device for producing an aerosol for inhalation by a person includes a mouthpiece located at one of opposite longitudinal ends of the device; a liquid container; a transducer that, when actuated, causes a liquid from the container to be aerosolized such that the aerosol may be inhaled from the device by a person through the mouthpiece; and circuitry and a power supply for actuating the transducer. The mouthpiece, the container, and the transducer are located in-line along a longitudinal axis of a housing of the device extending between the opposite longitudinal ends of the device. The container is located between and separates the transducer and the mouthpiece. The container and the transducer are contained within a cartridge that is insertable into and removable from the housing of the device. The container and the transducer are replaceable by the person when the liquid in the container is depleted.

Abstract: The invention relates to a dispensing device which is intended for spraying a sprayable fluid and is designed in the form of a hand-held unit, having a housing (12), in which are provided an air pump (22) and an electric drive motor (18), which drives the air pump (22), having a spray head (14), which is connected to the housing (12) and is intended for dispensing the fluid, having an accommodating chamber (29), which is arranged in the housing (12) and is intended for a storage container (41), in which the fluid which is to be dispensed is stored, having a fluid line (44), which leads from the storage container (41) to the spray head (14), and having a hose line (36), which leads from the air pump (22) to the spray head (14), wherein the spray head (14) has a first nozzle (46), which is connected to the fluid line (44), and, separately from said first nozzle, a second nozzle (38), which is supplied with the air flow from the hose line (36), and an atomizing zone (49) is formed outside the spray head (14).

Abstract: A biofilm disrupting composition for use on chronic wounds comprising (i) at least one biologically acceptable thiol based antioxidant (ii) at least one biofilm disruptor and (iii) at least one biocide. Also disclosed is a process of preparing the composition. Also disclosed is the use of the composition for the manufacture of a medicament for the treatment of a chronic wound, and a method of treating a chronic wound in a patient comprising administering the biofilm disrupting composition.

Abstract: A nebulizer system capable of identifying when activation has occurred and aerosol is being produced. The nebulizer system monitors the inhalation and exhalation flow generated by the patient and communicates proper breathing technique for optimal drug delivery. The nebulizer system may monitor air supply to the nebulizer to ensure it is within the working range and is producing, or is capable of producing, acceptable particle size and drug output rate. When a patient, caregiver or other user deposits or inserts medication into the nebulizer, the nebulizer system is able to identify the medication and determine the appropriate delivery methods required to properly administer the medication as well as output this information into a treatment log to ensure the patient is taking the proper medications. The system is able to measure the concentration of the medication and volume of the medication placed within the medication receptacle, e.g., bowl.

Abstract: Disclosed is a computer controlled dosage system, for dosage adjustment for a mobile, hand held, inhaler for delivering a dosage of a medicine, is provided. The system comprises at least one measuring device for measuring at least one parameter; and a handheld mobile computer separate from the inhaler, the computer being configured to communicate with the at least one measuring device and with a remote memory for sending and receiving information to and from patient medical records of the remote memory for storage in a memory of the computer, and the computer being configured to receive a manual input for storage in the memory of the computer. The computer is configured to create a data set for setting a plurality of levels of different dosages of medicine based on the medicine used by the inhaler, the information from the patient's medical records of the remote memory, and the manual input; and the computer is further configured to store the data set in the memory of the computer.

Abstract: The present invention is directed to an electrically conductive substrate (1002) coated with one or more herbal essences wherein the substrate may be a flat sheet of conductive metal or polymer. The coating (1120) may be present as separate sections on the substrate and multiple conductor contacts may be present on the substrate or may be separate components. Multiple coated substrates may be stacked together to form a cartridge for use in an herbal essence delivery device.

Abstract: A nebulizer unit includes a housing, which includes an aerosol generator with a feed chamber disposed at one side, an ampoule receiver, an opening device with at least one opening, which is in communication with the feed chamber, and an ampoule with liquid, which comprises at least one opening, with which it can be inserted or used in the ampoule receiver, wherein the ampoule has a connection region, which interacts with a connector of the ampoule receptacle in order to hold the ampoule firmly in the ampoule receiver and to connect the openings and such that they are leak tight.