Abstract: In general, a dialysis device includes a first processing device for monitoring dialysis functions of the dialysis device, a second processing device, a display device, and memory. The memory is configured to store instructions that, when executed, cause the dialysis device to provide, on the display device, a first display region and a second display region, where the first display region is associated with the first processing device and the second display region is associated with the second processing device. At least a portion of the first display region cannot be obscured by the second display region.

Abstract: Methods, systems, and apparatuses for integrating medical device data are disclosed. In an example embodiment, an integration engine includes a configuration interface configured to receive a patient identifier. The integration engine also includes a subscription processor configured to transmit a first message, including the patient identifier, to a first gateway to receive infusion therapy progress data from at least one infusion pump and transmit a second message, including the patient identifier, to a second gateway to receive renal failure therapy progress data from at least one renal failure therapy machine. The integration engine further includes a data processor configured to receive the infusion therapy progress data from the first gateway, receive the renal failure therapy progress data from the second gateway, and cause a combination user interface to display the infusion therapy progress data and the renal failure therapy progress data.

Abstract: Devices, systems, and methods can be used to deliver temperature-controlled medical fluids to patients. For example, this disclosure provides devices, systems, and methods for controlling the temperature of dialysate delivered to a patient during a peritoneal dialysis treatment.

Abstract: The present invention concerns an anticoagulation fluid comprising 10-40 mM citrate and 0.1-4 mM phosphate. The anticoagulation fluid is to be used for regional citrate anticoagulation in an extracorporeal blood circuit. The anticoagulation fluid may be combined with at least one treatment fluid in the dialysis treatment, and it may be included in a system for regional citrate anticoagulation in an extracorporeal blood circuit.

Abstract: The present invention relates to a method for calculating or approximating a value representing the relative blood volume (RBV) at a certain point of time, or a value representing the refilling volume of a patient that may be observed or found during or due to a blood treatment of the patient, the method involving considering one or more calculated or measured value(s) reflecting an overhydration level of the patient or an approximation thereof. It relates further to an apparatus and a device for carrying out the present invention, a blood treatment device, digital storage means, a computer program product, and a computer program.

Abstract: A method for determining or approximating a patient's daily loss of iron (fe_loss), the method comprising the steps of determining the patient's iron uptake (fe_uptake); determining the quantity of iron stored within the patient's body; and determining the patient's daily loss of iron based on the patient's iron uptake (fe_uptake) and the quantity of non-functional iron stored within the patient's body. The method relates further to apparatuses and an erythropoesis stimulating medicament for use in the treatment of anaemia. Finally the present invention relates to digital storage means, a computer program product, and a computer program.

Abstract: An extracorporeal blood treatment apparatus (1) comprising a control unit (10) connectable to a blood warming device (200). The apparatus (1) comprises: an extracorporeal blood circuit (100) and at least one infusion line (15, 21, 25) connected to the extracorporeal blood circuit (100). A control unit (10) is configured to execute the following procedure: receiving a first value representative of a desired blood temperature (Tdes) at an end (70) of a blood return line (7) configured to be connected to a venous vascular access of a patient (P); receiving at least a first signal relating to at least a flow rate (QPBP, QREP1, QREP2) of an infusion fluid in the at least one infusion line (15, 21, 25); calculating a set point value of an operating parameter (TOUT; Pw) to be imposed on the warming device (200) configured to heat a blood heating zone (H) of the extracorporeal blood circuit (100) in order to maintain the desired blood temperature (Tdes) at the end (70) of the blood return line (7).

Abstract: A system includes a dialyzer having a blood side and a dialysate side, a first extracorporeal circuit including one or more first fluid connectors for connecting the blood side of the dialyzer to the vascular system of a kidney patient, a second extracorporeal circuit including one or more second fluid connectors for connecting the dialysate side of the dialyzer to the vascular system of a healthy animal, a first pump in fluid communication with at least one of the first and second extracorporeal circuits, and a driver mechanically coupled to the first pump, where the driver is configured to drive the first pump using energy from an energy source.

Abstract: A leak may be detected in a heat exchanger of a hemodialysis device. A drain valve is opened by the controller, and then closed by the controller after a pre-selected time period. An initial pressure is determined in the spent dialysate circuit and stored in the memory. A system pressure is determined at periodic time intervals and compared to a pre-determined maximum pressure. The controller then determines whether the heat exchanger has a leak, in that in response to the system pressure exceeding a predetermined maximum pressure, a command is generated to execute an event including suspending a disinfectant operation with a disinfecting agent, and in response to the initial pressure subtracted from the system pressure being greater than a predetermined minimum pressure differential, a command is generated to execute an event including suspending the cleanse operation with the disinfecting agent.

Abstract: A screw connector includes a first connector with a first lumen and an outside thread, and a second connector with an elastically deformable nut and an inside thread. The outside thread has a first formation and the nut has a second formation, the second formation is a recess in the base of the nut, and the inside thread and the outside thread are configured for mutual connection. The nut is configured for deformation by the first formation in a first angle-of-rotation range without the first formation engaging in the recess, and the inside thread, the outside thread, the first formation, and the recess are configured for engaging the first formation when the inside and outside threads are connected in a second angle-of-rotation range. The screw connector has a half-open sterilization position in the second angle-of-rotation range. In another range, the screw connector may be tightened to be gas-tight and/or liquid-tight.

Abstract: A screw connector for medical hose systems is configured for catch engagement in a half-open sterilization position. The connector includes a first connecting element having a first lumen and an outside thread, and a second connecting element having a second lumen, and an elastically deformable union nut having an inside thread. The inside thread and the outside thread are configured to be screwed together, with the outside thread having a first formation and the inside thread a second formation, with deformation of the nut via the first formation in a predetermined first angle-of-rotation range without engaging the second formation. The inside thread and the outside thread, and the first formation and the second formation, are configured for catch engagement of the first formation in the second formation when the inside thread and the outside thread are screwed together in a predetermined second angle-of-rotation range to provide the half-open sterilization position.

Abstract: A blood purification apparatus comprising: a blood circuit including an arterial blood circuit and a venous blood circuit and that is capable of extracorporeally circulating blood of a patient from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a blood purification device provided between the arterial and the venous blood circuit of the blood circuit and that is capable of purifying the blood flowing in the blood circuit; a dialysate introduction line for introducing dialysate into the blood purification device and a dialysate drain line for discharging drain liquid from the blood purification device; a liquid delivery pump provided to the dialysate introduction line and that is capable of causing the dialysate in the dialysate introduction line to flow; a heating device that is capable of heating the dialysate to be introduced from the dialysate introduction line into the blood purification device; a temperature-detecting device that is capable of detecting a temperat

Abstract: Disclosed is a cardiopulmonary resuscitation training apparatus. The cardiopulmonary resuscitation training apparatus comprises: a mannequin; a compression plate which is provided towards the chest area of the mannequin and generates a return force; and a display unit which displays the state of the mannequin and shows blood circulation movement in light-emitting lines, in accordance with the pressing of the compression plate. The display unit can be constituted in such a way that the blood circulation movement in the mannequin is displayed by means of LEDs, and the LED movement rate is varied or the LEDs emit light in different colours in accordance with the depth of pressing or the pressing rate of the compression plate. This gives the advantage that the user can implement cardiopulmonary resuscitation close to reality while being made aware of the compression depth and the compression rate.

Abstract: Systems and methods are provided for performing selective sorbent-based regeneration of dialysate. The systems and method provide for dialysate regeneration to be carried out intermittently throughout a dialysis session, decreasing the necessary amounts of sorbent materials and infusates to conduct dialysis. The system and methods allow for regeneration of dialysate as needed based on the concentration of waste species in the dialysate, allowing for effective treatment with a decreased need for sorbent materials.

Abstract: A renal failure therapy machine includes a blood cleaning filter, a dialysis fluid circuit including a balance chamber, the balance chamber including a fresh dialysis fluid compartment configured to send fresh dialysis fluid to the blood cleaning filter and a used dialysis fluid compartment configured to receive used dialysis fluid from the blood cleaning filter, a fresh dialysis fluid line in fluid communication with the fresh dialysis fluid compartment of the balance chamber and the blood cleaning filter, and a flow restrictor in fluid communication with the blood cleaning filter, the flow restrictor configured to cause fresh dialysis fluid delivered from the fresh dialysis fluid compartment, through the fresh dialysis fluid line, to the blood cleaning filter to be pressurized so that a first amount of the fresh dialysis fluid performs convective clearance and a second amount of the fresh dialysis fluid performs diffusive clearance.

Abstract: A portable irrigation system comprising a reservoir for an irrigating liquid, a probe for arrangement in a user, an electrical system, a control unit for controlling the transfer of irrigation liquid and tubing providing fluid communication between said reservoir, control unit and probe.

Abstract: A gas exchange system may include an elongate member including a liquid circuit and configured to be inserted into a body lumen, and a gas exchanger in fluid communication with the elongate member. A gas transfer fluid may be disposed within the liquid circuit of the elongate member. The gas transfer fluid may be configured to absorb carbon dioxide from a body fluid disposed in the body lumen, and subsequently release the carbon dioxide in the gas exchanger.

Abstract: The blood purification system includes a plurality of monitoring devices (1) with a dialyzer (5) to perform a blood purification treatment on a patient. A dialysate supplying device (2) supplies a dialysate to each of the monitoring devices (1). The plurality of monitoring devices (1) and the dialysate supplying device (2) are connected to each other by a LAN cable ?. Predetermined information can be transmitted from the dialysate supplying device (2) to a specified monitoring device (1), out of the plurality of monitoring devices (1). The specified monitoring device (1) can perform an individual operation.

Abstract: The present invention relates to a test system or an assay system (detection system) and test method preferably for use in the Point-of-Care (PoC) field.

Abstract: Apparatus and control methods for determining a distribution volume of at least one uremic substance in a dialysis patient are disclosed. The apparatus may include a dialyzer, an optional flow rate measuring system for detecting the flow rate of a dialysis fluid through the dialyzer, a dialysis fluid measuring system for detecting at least one dialysis fluid parameter that depends on the at least one substance in the dialysis fluid, and a computer for establishing a dialysis dose based on the dialysis fluid parameter and for establishing the distribution volume based on the dialysis dose taking a clearance factor and dialysis duration into account.

Abstract: A filter CF1 for filtering dialysis fluid comprises the following: a housing 52 inside of which a filter material 51 is accommodated and which is vertically long; an introduction port 53 that is disposed in the lower part of the housing and that introduces dialysis fluid from an upstream-side flow path 23a; a filtered fluid lead-out port 54 through which filtered dialysis fluid, which has passed through the filter material, is lead out from the upper part of the housing to a downstream-side flow path 23b; and an unfiltered fluid lead-out port 55 through which unfiltered fluid is lead out from the upper part of the housing to a waste fluid flow path 57. When removing the filter from a dialysis fluid circuit 4, fluid is suctioned from the inside of the housing via the upstream-side flow path by using fluid suction means 64A, and a gas is caused to flow into the housing from at least either one of the waste fluid flow path and the downstream-side flow path by using gas inflow means 65.

Abstract: Provided herein are anti-angiogenic monoclonal antibodies and antigen-binding antibody fragments that selectively and specifically bind to an epitope in both fibronectin and either fibrinogen or fibrin fragment E, compositions containing these antibodies and antibody fragments, and methods of using these antibodies and antibody fragments.

Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patent parameters. By comparing the patient's current parameters to past parameters in response to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

Abstract: A tubular medical fluid flow set comprises a pressure sensing chamber connected in flow-through relation to fluid flow tubing of the set. The pressure sensing chamber defines a movable, flexible, impermeable diaphragm dividing the chamber into two separate compartments. The fluid flow tubing communicates with one of the compartments and is isolated from the other of the compartments. A port is carried on the chamber, the port having a seal therein, and communicating with the other of the compartments. Thus, the other of the compartments is hermetically sealed until the port is opened for connection with a pressure measuring device, to keep the flexible diaphragm in a desired, initial position prior to opening of the seal.

Abstract: The invention relates to a method for testing at least one function of a medical functional device which is inserted in and connected and compressed with a medical treatment apparatus, and/or a function of this treatment apparatus, wherein between a hydraulic device or a pneumatic unit of the treatment apparatus and the functional device at least one fluid communication is established. It further relates to a detection device which is programmed and/or configured for executing the method according to the invention as well as a medical treatment apparatus which comprises at least one detection device and/or is in signal transmission or is connected for signal transmission with it, a digital storage medium, a computer program product as well as a computer program.

Abstract: A method of rinsing and/or filling a blood treatment device, in particular for priming a blood treatment device, is associated with a blood treatment device that includes a membrane filter, in particular a hollow fiber membrane filter, a first partial circuit, and a second partial circuit. The first and the second partial circuits are separated by the membrane filter in a semipermeable manner, with temporarily the first partial circuit being first filled with a fluid with a uniform and/or a pulsatile first volumetric flow rate, with the volumetric flow rate not exceeding a specified threshold value at which the fluid has not completely wetted and/or soaked the membrane. The second partial circuit is temporarily open towards the atmosphere, air is displaced from the first partial circuit into the second partial circuit via the membrane, and during filling no negative pressure is applied to the first partial circuit.

Abstract: Medical devices including a vial adapter with an inline dry drug module for use with a vial, a needleless syringe and a carrier liquid for filling the needleless syringe with an injection solution for injection to a patient. The inline dry drug modules include a dry drug storage component for storing a dry drug dosage and a uniform carrier liquid distribution component for promoting uniform contact of the dry drug storage component by the carrier liquid to form an injection solution from the dry drug dosage. The inline dry drug modules can include a discrete dry drug storage component and a discrete uniform carrier liquid distribution component or a dual purpose component for both drug storage and uniform carrier liquid distribution. The vial adapters can be provided in vented or non-vented versions.

Abstract: A method is provided of monitoring the leak tightness of a plurality of pneumatically or hydraulically actuated actuators of a machine, in particular a plurality of valve actuators of a medical treatment machine, in which pressure is exerted on the actuators in different combinations during operation of the machine. A common pressure drop occurring during a stationary operating phase at the actuators on which pressure is exerted in the respective combination is measured for a plurality of different combinations of actuators on which pressure is exerted. A respective leak tightness value is determined for individual actuators and/or groups of actuators, with the pressure drop measured for those combinations and in which the respective actuator and/or the respective group of actuators on which pressure is exerted being accounted for in the leak tightness value. A machine, in particular a medical treatment machine, is configured to effect the valve actuator monitoring.

Abstract: Extracorporeal blood treatment systems and methods to detect the connection of one or more components (e.g., of an extracorporeal blood set) thereto (e.g., to one or more pressure transducers contained in the system housing) by, for example, controlling an air pump apparatus to provide air to a connection port at which the component is to be connected and monitoring pressure resulting therefrom to detect whether the component is operatively connected (e.g., based on a detected change in the monitored pressure due to the increased resistance, based on a monitored rate of decay of pressure of injected air, etc.).

Abstract: A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (C) for connecting the blood circuit (20) to the vascular system of a patient. The blood circuit (20) comprises a blood processing device (6), and at least one pumping device (3). The control system is operable to switch between a pre-treatment mode and a blood treatment mode. The blood treatment mode involves operating the blood circuit (20) to pump blood from the vascular system via the connection system (C) through the blood processing device (6) and back to the vascular system via the connection system (C). The control system (23) is operable to obtain measurement data from at least one energy transfer sensor (40) arranged to sense a transfer of energy between the patient and the connection system (C) or between the patient and the blood circuit (20).

Abstract: Novel low-pressure nanofiltration membrane composites for rejecting organic compounds are prepared by interfacial polymerization on a microporous hollow fiber supporting membrane. The interfacial polymerization reaction is carried out using an essentially monomeric polyamine reactant having at least two amine functional groups per molecule, and an essentially monomeric amine-reactive polyfunctional aromatic or cycloaliphatic acyl halide having at least two acyl halide groups per molecule. The composite can be fabricated by stepwise polymerization reactions with different reactant recipes at each step.

Abstract: Described herein is a smart module configured to work with injection devices. The smart module may include electronics such as sensors and indicators, and be programmed to detect environmental parameters. If the sensors detect that a parameter is outside of a predetermined boundary or range, then the indicators may be activated to notify the user that the injection device may not be safe for administering medicine.

Abstract: The present invention relates to water purification systems and uses thereof. In particular, the present invention relates to the use of water filtration systems to combat Legionella bacterial contamination of industrial and commercial water systems, such as grocery store misting systems.

Abstract: A device is configured to monitor the integrity of a connection system between first and second fluid containing systems comprising first and second pulse generators. A pressure sensor is arranged in the first fluid containing system to detect first pulses originating from the first pulse generator and second pulses originating from the second pulse generator. The device operates a monitoring method, by generating (42) a time-dependent pressure signal based on measurement data obtained from the pressure sensor such that the pressure signal contains a sequence of apparent pulses. The apparent pulses represent a superposition of the second pulses on the first pulses when the connection system (C) is intact. The device processes (44) the pressure signal to calculate a parameter value based on a pulse feature of at least one of the apparent pulses in the pressure signal.

Abstract: The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising sodium chloride, at least one dry acid and at least one calcium salt, and optionally potassium salt, magnesium salt, and glucose. According to the invention said at least one calcium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.

Abstract: Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysis systems may include a safety system utilizing a field programmable gate array (FPGA) that monitors at least conductivity and temperature of dialysate in the flow circuit upstream of a dialyzer and enters a fail-safe state if the measured conductivity is outside of a range of values. The FPGA may be verified to be operating properly by exposing sensors in fluid paths to temperatures or conductivities that are outside pre-determined permissible ranges of values, and confirming that the FPGA safety system enters a fail-safe state in response to the temperatures or conductivities. The FPGA may be configured to monitor an amount of ultrafiltration fluid withdrawn from a patient during dialysis treatment and to enter a fail-safe state if a maximum amount is exceeded.

Abstract: A filling device of a fluid conducting system of an extracorporeal blood treatment device is disclosed. The filling device includes a spike that is adapted for connection to a single fluid connector of a medical fluid container of the fluid system and a manually operable fluid blocking mechanism that is arranged directly downstream of the spike and is adapted or provided in such a way so as to remain fluidly connected with the spike while the filling device is in operation. The fluid blocking mechanism has at least one fluid outlet connector that is adapted so that a line section or hose of the fluid conducting system, preferably an arterial line section of a blood purification device, can be connected to it in a detachable manner while the filling device is in operation.

Abstract: The invention relates to a dialysis device (1) having a dialysate circuit comprising a first dialyzer (3) and a second dialyzer (5) wherein the first dialyzer (3) is connectable to a blood circulation of a patient via a blood feed line (11) and a recirculation (13), an effluent for a retentate flow (Qeffluent) from the dialysate circuit to the second dialyzer (5) is provided and a permetate stream (Qout) of the second dialyzer (5) in the dialysate circuit is passed to the first dialyzer (3), the second dialyzer (5) comprising a filter membrane having a cut-off value of at least 500 Da and the first dialyzer (3) comprising a filter membrane having a cut-off value exceeding that of the second dialyzer (5).

Abstract: A method of assessing biofilm thickness in a membrane supported biofilm reactor (MSBR) of the type comprising a lumen containing a gas phase, a liquid phase, and a gas permeable membrane providing an interface between the gas and liquid phases, the method comprising the steps of charging the lumen with an inert gas, closing the lumen to establish an initial elevated pressure in the lumen, measuring the rate of change of pressure within the lumen, and correlating the rate of change of pressure (dP/dt) with biofilm thickness. The step of correlating dP/dt with biofilm thickness involves correlating dP/dt with the rate of diffusion of the inert gas (dn/dt), correlating dn/dt with an overall mass transfer coefficient (K), correlating K with the mass transfer coefficient of the biofilm (kB), and correlating kB with the biofilm thickness.

Abstract: Disclosed are hemodialysis and similar dialysis systems including fluid flow circuits. Hemodialysis systems may include a blood flow path, and a dialysate flow path including balancing, mixing, and/or directing circuits. Preparation of dialysate may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit and/or the various fluid flow paths may be isolated from electrical components. Fluid circuits and electrical components may be contained in a housing comprising a first section separated from a second section by a thermally insulating barrier. The first section may house a heater and heat-sterilizable components including liquid flowpaths, pumps or valves, while the second section houses electronic components for controlling the hemodialysis system. The insulating barrier may be configured to inhibit the second section from being exposed to sterilizing temperatures produced in the first section.

Abstract: A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (C) for connecting the blood circuit (20) to the vascular system of a patient. The blood circuit (20) comprises a blood processing device (6), and at least one pumping device (3). The control system is operable to switch between a pre-treatment mode and a blood treatment mode. The blood treatment mode involves operating the blood circuit (20) to pump blood from the vascular system via the connection system (C) through the blood processing device (6) and back to the vascular system via the connection system (C). The control system (23) is operable to obtain measurement data from at least one energy transfer sensor (40) arranged to sense a transfer of energy between the patient and the connection system (C) or between the patient and the blood circuit (20).

Abstract: The present invention relates to a method for detecting a permeability or patency of a section of an extracorporeal tube which is inserted in a tube pump, a detection device for executing a method according to the present invention, a medical treatment apparatus which comprises at least one detection device and/or is in signal transmission with it or is connected for signal transmission with it, a digital storage medium, a computer program product as well as a computer program.

Abstract: A gas separation membrane module, comprising: a hollow fiber element having a hollow fiber bundle consisting of a number of hollow fiber membranes and a tube sheet provided at an end of the hollow fiber bundle for binding the hollow fiber membranes; a vessel having an opening through which the hollow fiber element is inserted or removed; a lid member having a gas outlet formed therein and attached to cover the opening of the vessel; and a perforated plate having a plurality of through holes for forming gas channels formed therein, the perforated plate being mounted between the tube sheet and the lid member, the gas separation membrane module performing gas separation by supplying mixed gas to the hollow fiber membranes.

Abstract: An apparatus for extracorporeal blood treatment is described, including a treatment unit, an extracorporeal blood circuit, an infusion line of a replacement fluid, a dialysis line connected in inlet to the second chamber, and a fluid evacuation line; sensors for determining a first parameter relating to a patient's blood volume (BV %) a second parameter relating to an ultrafiltration flow rate (UFR) or to a patient's weight loss rate (WLR), a third parameter (Cd, Na) relating to a conductivity or concentration of a liquid crossing the dialysis line and/or the infusion line, and a fourth parameter relating to an infusion flow rate (QINF), and a control unit for performing a control procedure.

Abstract: A portable hemodialysis system is provided suitable for in home use. The hemodialysis system includes a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialyzer, and a dialysate flow path and a blood flow path which flow in opposing directions through the dialyzer. In addition, the disposable cartridge possesses pump actuators (but not pump motors) for pumping dialysate and blood through their respective flow paths. The pump actuators having non-deformable components including a housing having a central cavity forming an internal sidewall, a rotor eccentrically positioned within the cavity having radially aligned slots at the rotor's periphery, and vanes slideably positioned in the slots to slide in and out of the slots so as to seal with the cavity's internal sidewall creating vane chambers that pump blood or dialysate.

Abstract: A method performed on a dialysis machine includes receiving a first value that represents a pre-dialysis body weight of a patient and receiving a second value that represents a volume of liquid (V) inside a body of the patient. The method also includes administering dialysis to the patient, calculating an instantaneous body weight (W) of the patient based at least in part on the first value, determining a length of time (t) for which the dialysis was administered to the patient, determining a dialyzer clearance (K) associated with the dialysis, and calculating, based at least in part on the length of time, the instantaneous body weight, the volume, and the dialyzer clearance, a urea reduction ratio (URR) associated with the dialysis.

Abstract: A dialysis system includes an extracorporeal circuit including a dialyzer; a dialysis fluid circuit including a first balance chamber, a second balance chamber, a fresh dialysis fluid pump in fluid communication with first and second fresh compartments of the first and second balance chambers, respectively, the first and second fresh compartments in fluid communication with a fresh dialysate fluid inlet of the dialyzer, and a spent dialysis fluid pump in fluid communication with first and second spent compartments of the first and second balance chambers, respectively, the spent dialysis fluid pump also in fluid communication with a spent dialysis fluid outlet of the dialyzer; and wherein the system is configured to run a priming sequence that uses (i) at least one of the fresh and spent dialysis fluid pumps and the first and second balance chambers to pump dialysis fluid through the dialysis fluid circuit and (ii) at least one of the fresh and spent dialysis fluid pumps to pump dialysis fluid through the dia

Abstract: A sensor line for monitoring for and locating leaks in an installation, in which chlorine escapes to the area surrounding the installation if there is a leak. The sensor line contains a carrier pipe. The wall of the carrier pipe has openings which are closed by at least one layer which is permeable for chlorine and contains a halogen-containing siloxane rubber.

Abstract: A method for priming a hemodialysis treatment includes (i) providing a sorbent cartridge for cleaning spent dialysate fluid returning from a dialyzer; (ii) preparing a batch of dialysate in a quantity commensurate with being recycled through the sorbent cartridge multiple times; (iii) priming a dialysate circuit in fluid communication with the dialyzer using the batch of dialysate; and (iv) reversing a blood pump at least one time to prime a blood circuit in fluid communication with the dialyzer using a biologically safe fluid other than dialysate.

Abstract: A system and method for providing slow dialysate flow with an intermittent hemodialysis delivery (IHD) system are disclosed. The system includes a dialysate slow-flow fluid pump having an outlet for connection to an inlet port of a hemodialyzer and an inlet for connection to a dialysate bulk flow line in association with the IHD. The system further includes an outlet line for coupling an outlet port of the hemodialyzer back to the dialysate bulk flow line, wherein the dialysate slow-flow fluid pump is configured to control the rate of delivery of dialysate to the hemodialyzer.