Abstract: The present invention is a collection assembly comprising a container, a cap assembly removably and sealably secured to the container, whereby access to the interior of the container can be made with a piercing element without removing the cap assembly from the container. The cap assembly includes a cap body and a membrane like septum supported by the cap body. The septum provides for a pierceable element to have access to the interior of the container. The membrane is a thermoplastic elastomer and is self-sealing upon removal of the piercing element.

Abstract: A closure for receptacles such as bottles which includes an annular sealing member which is internally reinforced by a cylindrical core. The cylindrical core includes a helically or spirally shaped frangible structure along which the cylindrical core can be pulled, stripped, unwound or torn apart. The closures can be pressed into receptacles using conventional methods. To remove the closures, one pulls, strips or tears the cylindrical core apart. The remaining, unreinforced annular sealing member can be easily removed.

Abstract: The plug comprises a body (1) permanently coupled to the neck of a container for an air freshener or insect repellent liquid, with evaporation occurring through a wick (11) axially coupled in a concentric passage of the plug itself. An inner part of the axial passage of the plug in which wick (11) is inserted is provided with slits (7) along the main generatrix line, forming sectors (9) provided with semi pyramidal projections (12), defining means which allow motion in the direction of insertion of wick (11) and prevent its displacement in the outwards direction for removing said wick (11) from the plug, which prevents the container on which the plug is applied from being refilled with a product other than the original.

Abstract: A plastic foamed synthetic closure for use with liquid bearing containers which closely simulates natural cork products is realized by incorporating color concentrates into the polymer melt and forming the color concentrates into elongated streaks. The desired emulation is further enhanced by arcuately pivoting the foamed plastic material during the production to form curved or sinusoidal-shaped streaks. This invention also provides manufacturing methods for mass producing individual products in a continuous motion casting system wherein fully complete products are formed in polymer casting members, which receive foam material exiting from the die and allow the foamed material to be formed in a continuous operation in the casting members. Finally, the present invention also teaches a unique system for maintaining and delivering carbon dioxide in its supercritical phase for use as a blowing agent.

Abstract: A closure for a vial includes a head portion, and a stem portion which projects from a lower surface of the head portion, the stem portion being inserted in an opening of a vial; wherein the stem portion is provided with a small diameter portion and a seal portion, in that order from the lower surface the head portion, the diameter of the small diameter portion being smaller than the diameter of the seal portion. The entirety of the small diameter portion and the seal portion are substantially uniformly fitted in the opening of the vial.

Abstract: A stopper for containers, such as wine bottles, comprises:

Abstract: It has been discovered that the presence of an antioxidant in a closure or stopper, particularly in a synthetic closure or stopper, used to seal liquid products in a container causes excessive extraction forces to be required to remove the closure/stopper from the container. In particular, in sealing wine in a wine bottle, wherein the closure/stopper remains in the bottle for extended periods of time, the presence of the antioxidant causes increased extraction forces to be required. In accordance with the present invention, by reducing and controlling the amount of antioxidant employed in forming the closure/stopper, excessive extraction forces are controlled and remain at normal levels.

Abstract: Subject of the present invention is multifunctional protective component. This new component provides simultaneous protection against voltage strokes and against both high and low frequency disturbances. It is composed of two discrete chip components, namely of multilayer ZnO polycrystalline diode and multilayer ceramic condenser or multilayer self-limiting condenser and multilayer ceramic condenser, which are mutually mechanically connected with non-conductive low-temperature glass (frite), parallel electrical connection between both chips being created with second metallization, and common outer electrodes of newly formed chip. This new component is suitable for surface mounting as well as in terminal leads form.

Abstract: An obturator for an aperture (8) produced in a metal sheet (9) has a central dome (1), a peripheral lip (3) and an annular part (3) extending between the dome (1) and the lip (2). The annular part (3) has a shoulder (4). The dome (1) is adapted to deform between a starting position and a locking position of the obturator in which the dome (1) is turned inside out in relation to the starting position. The annular part is adapted to expand between the starting position and locking position and is maintained expanded by the inverted dome (1) in the locking position. The lip (2) is adapted to come into abutment against a face (9a) of the aperture (8) and the shoulder (4) is adapted to be in abutment against an opposite face (9b) of the aperture (8) in the locking position.

Abstract: A stopper for sealing containers for pharmaceutical liquids, especially infusion bottles, which stopper has a collar, which projects into the neck of the container; an edge, which rests on the neck of the container; and a puncture area, enclosed by the edge and the collar, the stopper being held on the neck of the container by a protective cap of metal or plastic, characterized in that the puncture area (3) is designed to have such elasticity and flexibility with respect to the edge (9) and the collar (6) that, after the stopper has been inserted into the neck (4) of the container, the puncture area bulges slightly outward; and in that, after the puncture needle (15) of an infusion kit (16) has been inserted into the stopper, the puncture area bulges down into the neck (4) of the container.

Abstract: A stopper for sealing containers for pharmaceutical liquids, especially infusion bottles, which stopper has a collar, which projects into the neck of the container; an edge, which rests on the neck of the container; and a puncture area, enclosed by the edge and the collar, the stopper being held on the neck of the container by a protective cap of metal or plastic, characterized in that the puncture area (3) is designed to have such elasticity and flexibility with respect to the edge (9) and the collar (6) that, after the stopper has been inserted into the neck (4) of the container, the puncture area bulges slightly outward; and in that, after the puncture needle (15) of an infusion kit (16) has been inserted into the stopper, the puncture area bulges down into the neck (4) of the container.

Abstract: The reclosable container (1), adapted to reduce the risk of contamination of the substance contained therein, comprises a hollow body (2) provided with a dispensing mouth (15) which can be plugged through respective detachable closure elements (4, 20, 23) which comprise plugs (6, 6b, 6c, 21, 21b, 25) which can be coupled to the mouth (15); the closure elements (4, 20, 23) are monolithic with the container (1); the plugs (6, 6b, 6c, 21, 21b, 25) are located on the closure elements (4, 20, 23) on the side thereof directed towards the mouth (15). The method comprises the formation of the closure elements (4, 20, 23) nonlithically with the container (1); during formation, the plugs (6, 6b, 6c, 21, 21b, 25) are formed on the closure elements (4, 20, 23) on the side of these elements which is directed towards the mouth (15); at the end of the formation, the plugs (6, 6b, 6c, 21, 21b, 25) are made to couple to the mouth (15).

Abstract: By achieving an extruded, foamed core formed from plastic material peripherally surrounded and integrally bonded with a cooperating synthetic, plastic, extruded, outer layer, a unique, multi-component, multi-layer synthetic closure is provided which may be employed as a bottle closure or stopper for any desired product, whether the product is a liquid, a viscous material, or a solid distributed in a bottle or container and dispensed through the open portal of the container neck. The present invention achieves a mass producible, resilient, synthetic bottle closure which is employable for any desired bottle, including wine. By employing the present invention, a multi-component or multi-layer synthetic closure is attained which possesses physical properties substantially equal to or better than the physical properties found in cork material, which has caused such cork material to be the principal closure material for wine bottles.

Abstract: By achieving an extruded, foamed core formed from plastic material peripherally surrounded and integrally bonded with a cooperating synthetic, plastic, extruded, outer layer, a unique, multi-component, multi-layer synthetic closure is provided which may be employed as a bottle closure or stopper for any desired product, whether the product is a liquid, a viscous material, or a solid distributed in a bottle or container and dispensed through the open portal of the container neck. The present invention achieves a mass producible, resilient, synthetic bottle closure which is employable for any desired bottle, including wine. By employing the present invention, a multi-component or multi-layer synthetic closure is attained which possesses physical properties substantially equal to or better than the physical properties found in cork material, which has caused such cork material to be the principal closure material for wine bottles.

Abstract: A process of manufacturing a stopper comprises impregnating a cork body with an elastomeric substance such as a silicone rubber mixture. The cork is submerged in the mixture and a vacuum is applied to enhance penetration of the mixture into the cork. The cork is then cleaned by forcing it through a conduit to remove excess liquid, and cured. A thin coating, approximately 25 &mgr;m thick, of the rubber remains on the outer surface of the cork, so that its appearance and feel are not substantially different from that of an untreated cork.

Abstract: A transfer set assembly for transferring fluids between a first container, such as a conventional medical vial, having a sealed open end and a second container such as a conventional IV infusion bag. The transfer set includes a collar having a proximate tubular end portion for securement to the container, a needle cannula and holder assembly, which is telescopically received in a distal tubular portion of the collar, and a closure including a tubular body portion having an open proximate end which is telescopically received over the needle cannula and holder assembly and the distal tubular portion of the collar, a closed distal end portion and an inner tubular portion which is integral with the closed distal end. The inner tubular portion includes a free end having spiral camming surfaces which mate with spiral camping surfaces on the inside surface of the tubular distal portion of the needle cannula holder.

Abstract: A closure apparatus is provided that includes a plurality of plug closures interconnected by straps. Each plug includes a blind bore therein into which a sampling needle may be inserted for penetration of the plug in order to extract a sample from the container to which the plug is attached. The plugs are arranged within an array that may correspond to an array of containers set within wells located in a block array. A membrane is also provided that interconnects the straps and the plugs. The plugs are fashioned from an elastomer such as a silicone elastomer. A layer of PTFE is provided on the bottom outer surface of the plugs and may also be included on the underside of the interconnecting straps and membrane, so as to provide an inert barrier in contact with the contents of the containers.

Abstract: A fermentation device and a method for making a substance using the device are provided. The fermentation bung may have an outer plug that includes a central inner annular hole and a one or more holes surrounding the central hole, the outer plug fitting within a bung hole in a barrel in which a substance is going to be fermented. The device may further include an inner plug with a centrally extending stem that frictionally fits into the central inner annual hole of the outer plug to secure the inner plug into the outer plug and also have a top portion which covers the one or more holes surrounding the central hole. During the fermentation of the substance, the gases produced during fermentation may be vented through the device since the top portion of the inner plug may flex slightly to permit the escape of the gas. However, the device prevents any ambient air from entering the barrel since the top portion of the inner plug is covering the one or more holes.

Abstract: A convenient stopper for a bottle including a plug slidably retained in a cylinder by a connecting pin. The cylinder is sized to be received in an opening of the bottle. In a contracted mode of the stopper, the plug is disposed at the top of the connecting pin and away from the cylinder, whereby an outer wall of the cylinder contracts from the neck of the bottle, to allow easy removal from the bottle, without use of a corkscrew. In an expanded mode of the stopper, the plug is urged into the cylinder whereby the outer wall of the cylinder tightly seals the opening of the bottle. The stopper can be re-used to permit storage of remaining contents of the bottle to be consumed later.

Abstract: The invention relates to a stopper for use in a substantially cylindrical bottle opening. The stopper has a substantially cylindrical shape to seal the bottle opening and includes a first polymer portion and a second material portion, wherein the second material portion coaxially overlies the first polymer portion. In another embodiment, the stopper includes a third polymer portion wherein the first polymer portion coaxially overlies the third polymer portion. The invention also relates to a method of protecting liquid in a bottle with a substantially cylindrical bottle opening. The method includes providing a stopper having a substantially cylindrical shape to seal the bottle opening and closing off the bottle by insertion of the stopper into the bottle opening. The invention also relates to a method of producing a stopper for use in a substantially cylindrical bottle opening.

Abstract: Disclosed is a process for preparing cork articles, in particular cork stoppers for wine bottles, which involves treating cork with a phenol oxidizing enzyme. Preferred phenol oxidizing enzymes are laccase, peroxidase, catechol oxidase, and o-aminophenol oxidase. The treatment with a phenol oxidizing enzyme reduces the characteristic cork taint/astringency which is frequently imparted to the bottled wine.

Abstract: A device for the protection and containment of a distilled beverage is provided. The device has a heavy-gauge clear bottle, constructed of glass or plastic, with a bottle stopper which fits into a port hole cut through a top of the bottle. The bottle stopper is constructed having an easy-to-grip handle portion and a rod which extends through the port hole and into the containment portion of the bottle. A rubber ring is situated under a bottom portion of the handle and/or around the rod to provide a leak-proof seal between the port hole and rod so as to prevent spillage. Further, the bottle and bottle stopper fit into a durable transport case, constructed of an aluminum or heavy plastic material and having a linen or felt lining inside to ensure a snug fit of the bottle and bottle stopper into the case.

Abstract: A stopper for use with an individual beverage container is disclosed. The stopper has a generally tubular side wall with an upper edge and a lower edge. The side wall is dimensioned to fit snugly in the neck of the beverage container with a pressure fit. A bottom extends inwardly from the side wall. A flat upper portion is integrally attached to the bottom and is spaced upwardly from the bottom. An aperture is formed in the bottom or the flat upper portion. In addition, a vent hole is formed in the bottom or the flat upper portion. Preferably the flat upper portion is spaced from the side walls thereby forming a trough therebetween. Preferably the aperture is formed in the bottom and dimensioned to receive a straw snugly therethrough. Preferably the flat upper portion is divided into a first and second upper portion with a channel therebetween, with the channel being contiguous with the aperture and dimensioned to receive an upper portion of the straw when in a stored position.

Abstract: A stopper for use in a substantially cylindrical bottle opening is disclosed. The stopper is made of a synthetic elastomer body with a portion with a substantially cylindrical shape to seal the bottle opening. The elastomer body also contains a fiber portion or a plurality of fiber portions oriented substantially longitudinally in the elastomer body. The synthetic stopper is preferably designed to replace traditional wood bark corks in wine bottles. In one embodiment, the fiber reinforcement is in the form of a porous plug surrounded by an elastomer skin. In another embodiment, fibrous strips are dispersed throughout the stopper structure. The method of producing a stopper for use in a substantially cylindrical bottle opening is also disclosed as is a method of protecting a liquid in a bottle with a fiber reinforced synthetic elastomer stopper.

Abstract: A liquid transfer device for use in combination with a container and a syringe to facilitate removal of liquid from a container by the syringe includes an obstruction member positioned in an outlet of the container. The obstruction member has a concave inner surface facing the container interior to direct liquid to a passageway in the obstruction member when the container is inverted. A seal is formed between the obstruction member and the syringe spout and the spout is positioned by the obstruction member with the distal end of the spout located either in the passageway or projecting from the passageway toward the container interior and disposed closely adjacent to the inner surface of the obstruction member.

Abstract: A rubber plug includes a tubular body having a cross-sectionally corrugated inner surface including a plurality of conically shaped surfaces, and a plurality of lips formed integrally on and projecting radially outwardly from an outer surface of the tubular body in planes perpendicular to a longitudinal axis of the tubular body and including first, second and third lips, the plurality of lips being spaced along the longitudinal axis, wherein a distance between the first lip and the second lip in a direction of the longitudinal axis is different than a distance between the second and third lips in the direction of the longitudinal axis.

Abstract: Plug for capping or sealing the open ends of tubular members, such as tubular support members utilized on a Bimini boat top or other boat structure. The plug has a cap from which extend upper and lower rearwardly projecting tapered planar support panels each of which includes an outwardly protruding array of ramped teeth formed integrally therewith. The height of the teeth in each array increases incrementally from a minimum height near the end of the plug remote from the cap to a maximum height adjacent to the cap. The ramping of the teeth allows for accommodational frictional engagement of the teeth with various inside dimensions of tubular support members to secure the plug tightly therewithin. A hole extends transversely through the body of the plug for receipt of a pin for pivotally securing the end of a tubular support member containing the plug to a support bracket or other members.

Abstract: Plug for sealing or capping the open ends of tubular members, such as tubular rails or railing support members in boats. The plug has a cap from which extend upper, lower, right side and left side rearwardly projecting and connected planar panels. Each of the upper and lower planar panels and one of the side planar panels includes an outwardly protruding array of ramped teeth formed integrally therewith. The other side planar panel lacks an array of ramped teeth. The height of the teeth in each array increases incrementally from a minimum height remote from the cap to a maximum height adjacent to the cap. The ramping of the teeth allows for accommodational frictional engagement with various inside dimensions of tubular rails or railing support members to secure the plug tightly therewithin. A tapered indexing guide bar is located at the junction of the upper planar panel and the side planar panel which lacks an array of ramped teeth.

Abstract: The invention relates to a container seal with a sealing body which can be punctured for supplying or removing liquids to or from a container (3) by means of a blunt hollow needle (10), this sealing body consisting at least partially of a highly elastic material in which a cut is made at the puncture point (23) through at least 75% of its thickness. The seal can in this case be designed independently in the form of a stopper or as a small insert plate for a seal.

Abstract: The invention relates to a process for manufacturing a composition which can be used for producing stoppers.According to the invention, it comprises the following steps:a) sheets of cork are ground into small-sized granules,b) said cork granules are decomposed into granules having a high lignin content and into granules having a high suberin content, andc) the lignin-rich granules are separated from the suberin-rich granules in order to keep only the suberin-rich granules in said composition.The invention also relates to a composition comprising suberin-rich cork granules as well as to a stopper comprising such a composition.

Abstract: A tamper indicating bridged fitment is provided having an annular flange and an upwardly extending cylindrical side wall. Said fitment has a tamper indicating feature which is comprised of a bridge connected to the top edge of said upwardly extending cylindrical side wall by frangible webs. The tamper indicating bridge additionally has a slot formed longitudinally therethrough, said slot receiving a tab extending upward from a plug. The plug is a separate element which is comprised of a tab and a top wall and additionally has a downwardly extending cylindrical seal wall which acts to seal the fitment. Once the tab is inserted through the slot in the tamper indicating bridge, the fitment may only be opened by breaking the frangible tamper indicating webs connecting the bridge to the fitment side wall. Once the webs are broken, the plug may be removed by the tab and the bridge is thereby disconnected from the fitment.

Abstract: A new method fills a dispenser with cyanoacrylate adhesive from the rear. The container is sealed by a pressed-in base section (4). The latter has a vent opening which can be sealed, preferably by a plug (68) pre-mounted on it. Preferably the contacting surfaces of the container and this base have an oval shape. In this novel method, the container is first filled, while the end is still open. The base is then pressed in, sealing it onto the container. In so doing, the air displaced, is released through the base vent. During the final phase of pressing-in, the vent is plugged, irreversibly sealing it. Also claimed is an adhesive dispenser, essentially as described, with further preferred detail of the seals, the pipette construction of the container and a slot valve in the plug unit. USE--A dispenser filling method and dispenser, especially suitable e.g. for a super glue.

Abstract: A sealing plug cap includes a plug cap body fastened to the mouth of a sealing container to seal the passage of the mouth by a deformatable peripheral flap thereof, an air buffer device fastened to the bottom end of the plug cap body inside the sealing container to buffer the speed of air passing through a center air hole on the plug cap body, a socket mounted inside the plug cap body, and a sealing and relief control unit mounted in the socket, the sealing and relief control unit being forced by atmospheric pressure to close the air hole on the plug cap body when a suction pump is used to draw air out of the sealing container, the sealing and relief control unit being forced to open the air hole on the plug cap body when depressed.

Abstract: A bung comprises a deformable member with a generally cylindrical middle portion generally coinciding with the bunghole when inserted, and upper and lower frusto-conical ends which increase in diameter as each end extends from the middle portion. The middle portion is preferably of a size less than the hole to facilitate insertion of bung into and removal from the bunghole. Where the hole is tapered, the middle portion is similarly tapered. The spool-like shape of the stopper helps to prevent unintentional disengagement of the bung from the hole and to prevent overinsertion of the bung into the hole. The bung may further comprise one or more pull tabs to facilitate removal. The bung may define a bore to allow gas pressure to escape from the container, thus acting as a stopper. A rigid annular insert at the opening of the throughbore prevents deformation of the circular shape of the opening.

Abstract: An access plug flange is provided for inspection ports, for example on high temperature chemical processing vessels or pipes. The plug flange prevents heat loss through an access port formed in an insulative lining covering the vessel or pipe. The plug flange further does not deteriorate or lose its sealing effect despite its location near relatively high temperatures.

Abstract: The present invention provides connections and methods of restricting an opening. One connection according to the subject invention is configured to restrict a mouth of a container, the mouth having an inner surface having an inside diameter and an outer surface having an outside diameter, the connection includes: a plug having a side surface of varying dimension and configured to engage the inner surface to form a seal of the side surface of the plug and the inner surface; at least one intermediate member having a first end borne by the plug and a second end distally spaced from the first end; and a securing member configured to engage the outer surface of the container and the second end of the intermediate member, the intermediate member being configured to couple the plug and the securing member and maintain the seal of the side surface of the plug with the inner surface of the container.

Abstract: By achieving an extruded, foamed core formed from plastic material peripherally surrounded and integrally bonded with a cooperating synthetic, plastic, extruded, outer layer, a unique, multi-component, multi-layer synthetic closure is provided which may be employed as a bottle closure or stopper for any desired product, whether the product is a liquid, a viscous material, or a solid distributed in a bottle or container and dispensed through the open portal of the container neck. The present invention achieves a mass producible, resilient, synthetic bottle closure which is employable for any desired bottle, including wine. By employing the present invention, a multi-component or multi-layer synthetic closure is attained which possesses physical properties substantially equal to or better than the physical properties found in cork material, which has caused such cork material to be the principal closure material for wine bottles.

Abstract: A closure cover for panel openings is formed of plastic material and comprises a cover cap carrying several resilient elastic fingers that extend from a lower side of the cover cap. Each finger carries a stop element for penetrating into the panel opening and retaining the cover in place. The resilient fingers (3) are each comprised of two small resilient bars (6, 7) between which is arranged the stop element (8) likewise designed in the form of a small elastic cross piece. The stop element (8) forms a hook with a connection area (9) located at a predetermined angle relative to the bars (6, 7) and a stop area (5) connected to the connection area (9).

Abstract: A closure for sealing a sample tube and a method for establishing vacuum conditions within the tube while the closure is loosely positioned on the tube are provided. The closure comprises: (a) an inner stopper portion for insertion into the tube; and (b) an outer skirt portion for enclosing the tube, the skirt portion including at least two radially inwardly directed extensions for loosely positioning the closure on the tube, the extensions defining at least two passageways therebetween for exchanging gases between the interior of the tube and the surrounding atmosphere when the extensions are positioned on the tube. Preferably, the inner stopper portion and the outer skirt portion are integrally made.

Abstract: A spotting tip includes a tip body which is fitted on the end of a nozzle for sucking liquid contained in a container and inserted into the liquid in the container through a mouth of the container, and a lid member which is brought into contact with the mouth of the container and closes the space between the tip and the edge of the mouth when the tip is inserted into the container to a predetermined depth. At least one fine communicating passage is formed in at least one of the lid member and the tip body to communicate the inside and outside spaces of the container on opposite sides of the lid member.

Abstract: A closure for a beverage bottle includes a plug element having a disk shaped head portion and a hollow cylindrical portion which seals with the inner surface of the opening of the bottle. An annular projection is formed around the circumference of the bottle 12 near its mouth. The closure further includes a cap element which fits over the plug element and which includes with a skirt having an annular recess which locks onto the annular projection of the bottle. A first precut line is provided in the cap, extending around its circumference and a second precut line portion extends from the distal edge of the skirt to the first precut line across the annular recess. The cap may be disengaged from the bottle by cutting through the second precut line and the first precut line.

Abstract: A molded closure for a liquid container comprising a thermoplastic elastomer and a blowing agent. The molded closure is particularly suitable for use as a synthetic wine cork in a wine bottle. The molded closure does not permit passage of oxygen into the container, does not absorb oxygen from the contents of the container, can be removed from the container using a corkscrew without significant expansion, crumbling or disintegration, does not significantly taint a liquid in the container, permits the container to be placed horizontally immediately after insertion of the molded closure, and can permanently retain printed matter on its surface.

Abstract: A rubber plug for a drug vessel has at least one convexity formed on a surface of the rubber plug so that the rubber plug is prevented from sticking together, joining together under compression or joining together under suction with another rubber plug of a similar type. The convexity may preferably be a grain pattern formed on at least a part of the surface of the rubber plug by transferring same from a mold. A rubber plug for a drug vessel may also be composed of a leg portion and a head portion formed integrally with the leg portion and may have at least one convexity on at least one of the leg portion and the head portion.

Abstract: A pump adapted for insertion between a cap and a carbonated-beverage bottle for re-pressurizing the interior of the bottle with air, the pump comprising: a hollow, resilient, expandable and compressible body, the body having a sealed upper end and a lower end; a flanged lip seal formed around an outer circumference of the upper end of the hollow body and adapted for engaging an inside recess of a standard bottle cap; the upper end of the hollow body having a hole therethrough; a membrane closing the lower end of the hollow body, the membrane containing a normally sealed opening adapted to open in response to an increase in pressure caused by compression of the hollow body; and, a collar extending from the lower end of the hollow body and adapted to sealingly engage a bottle neck upon engagement of the collar with the bottle neck.

Abstract: A lyophilization closure assembly for a container or vial is disclosed. The lyophilization closure assembly is self-supporting with the container and may be employed with the container during a lyophilization process, eliminating the need for a separate crimping operation outside of the sterile environment in which lyophilization is conducted. The lyophilization closure assembly includes a body with a skirt disposed around the rim of the container. The skirt features one or more deflectable abutments and one or more deflectable latches positionable about the rim of the container, and defines one or more vapor passages. An elastomeric closure is retained within the body for sealing the open top of the medicament container. The elastomeric closure features a plug for sealing the open top of the container and a top surface facing away from the open top of the container. The body defines an opening over the elastomeric closure that delimits an access area on the top surface of the closure.

Abstract: A sterile closure assembly for a container or vial includes an elastomeric closure for sealing the open top of a medicament container. The elastomeric closure features a plug for sealing the open top of the container and a top surface facing away from the open top of the container. A washer is secured in surface contact with the top surface of the closure. The washer defines an opening that delimits an access area on the top surface of the closure for access by a fluid delivery device such as a syringe. A membrane is removably secured over the washer and hermetically encloses the access area of the elastomeric closure. The sterile closure assembly can be provided pre-assembled in a sterile state to assure the sterility of the top surface of the closure, obviating the need to sterilize the top surface of the closure, such as with an alcohol solution, prior to use of the vial.

Abstract: A cork cap having a head and a leg and adapted to be inserted in a bottle mouth. A cork is press-fitted in the cap so that its bottom end protrudes from the bottom of the leg and is pressed against the inner surface of the bottle mouth to seal the bottle mouth. The cork can be pulled out by pulling the cork cap while twisting it. Protrusions are formed on the inner periphery of the tapered inner surface of the head between adjacent ones of a plurality of vertical ribs. The protrusions bite into the cork, thus keeping the cork strongly coupled to the cork cap even when the latter is pulled and twisted. Thus, the cork can be reliably pulled out together with the cork cap by twisting and pulling only the cork cap.

Abstract: A vessel and closure assembly for culturing cells wherein a gas permeable membrane is provided in the closure to allow rapid and uniform equilibration of gases between the atmosphere of the vessel and the atmosphere of the incubator. A plug is provided for occluding passage of gases through the gas permeable membrane when the vessel is removed from the controlled atmosphere of the incubator.

Abstract: A dental amalgam mixing capsule including an inner capsule housed in an outer capsule. The inner capsule includes an elongated pestle telescopically extended into an open ended cap including a resilient, annular skirt formed with an annular sealing lip sized for frictional, gripping engagement with the pestle to define a storage chamber therebetween for storing a liquid component of the amalgam. The inner capsule may be made by subjecting the cap to a partial vacuum, inserting a charge of such liquid component therein, and registering one end of such pestle in sealing engagement with such sealing lip. Thus, when the assembly is returned to atmospheric pressure, the partial vacuum trapped in the cap will provide for a pressure differential across the pestle drawing it into the cap to fill the space therein.

Abstract: An improved closure insert is provided for throat region of a blow-molded container. This closure insert is provided with a rough perimeter and is permanently molded into the container throat region during container formation from a parison. The resulting seal resists loosening or disturbance when off-axis force or torque force is applied to the closure insert during container opening.