Abstract: The invention relates to an apparatus for applying slurries, comprising a doctor blade body with at least one separation element that subdivides the doctor blade body into different compartments, and to a method for producing a three-dimensional object using the apparatus according to the invention.

Abstract: In one example, a memory having instructions thereon that when executed cause a 3D printing system to repeatedly form each of multiple successive layers of powdered build material on a platform and apply a functional agent to build material in each layer, create a pressure difference across a thickness of build material on the platform, and increase the pressure difference over an extent of build material on the platform as the build material on the platform gets thicker.

Abstract: The present invention is directed to a co-processed lubricant excipient which can be used to manufacture tablets, and pharmaceutical compositions containing the same.

Abstract: An example of a build material slurry includes metallic particles having an individual particle size up to 20 ?m, from about 0.01 wt % up to 1 wt % of a water-soluble binder, based on a weight of the metallic particles, and water. The build material slurry is a ready-to-use three-dimensional (3D) printing build material.

Abstract: A polyacrylonitrile (PANi) based pharmaceutical composition providing a porous implant for use in treating spinal cord trauma and/or spinal cord injury. Particularly a pharmaceutical composition including polyacrylonitrile (PANi) and/or elastin (E) and/or collagen (C) to form a PANi-E and/or PANi-C and/or a PANi-EC polymer network. Particularly, a pharmaceutical composition including polyacrylonitrile (PANi), elastin (E), and collagen (C) together forming a polyacrylonitrile (PANi), elastin (E), collagen (C) polymer network (PANi-E-C), wherein the polyacrylonitrile (PANi) may be crosslinked to form a crosslinked interpenetrating polyacrylonitrile (PANi), elastin (E) and collagen (C) polymer network (xpi-PANi-E-C), and wherein secondary protein structures of elastin (E) and collagen (C) reorientate. The disclosure extends to use of the pharmaceutical composition in the treatment of spinal cord trauma and/or spinal cord injury.

Abstract: The present invention relates to a tablet comprising Afatinib or a pharmaceutically acceptable salt thereof, wherein the tablet is obtained by direct compression. The present invention further relates to a process for manufacturing a tablet of the invention as well as the use of the tablet of the invention.

Abstract: Polymer particles that comprise a thermoplastic polymer and a nucleating agent may be useful in additive manufacturing methods where warping may be mitigated. For example, a method of producing said polymer particles may comprise: mixing a mixture comprising a thermoplastic polymer, a nucleating agent, a carrier fluid, and optionally an emulsion stabilizer at a temperature at or greater than a melting point or softening temperature of the thermoplastic polymer to emulsify a thermoplastic polymer melt in the carrier fluid; cooling the mixture to form polymer particles; and separating the polymer particles from the carrier fluid, wherein the polymer particles comprise the thermoplastic polymer, the nucleating agent, the emulsion stabilizer, if included, and wherein the polymer particles have a crystallization temperature that is substantially the same as a crystallization temperature of the thermoplastic polymer prior to mixing.

Abstract: Provided are electrode active materials with a porous structure and including a metal, that when loaded with sulfur serve as electrochemically superior cathode active materials. The metal structures are optionally used on their own, are coated with another material, or coats another porous structure such as a porous carbon structure that allows for excellent retention of both sulfur and polysulfides, are conductive themselves, and show long term stability and excellent cycle life.

Abstract: The present invention relates to a modified release pharmaceutical formulation comprising one or more sustained release granules that may be prepared by over-mixing and hot melt granulation. The invention also relates to disintegrating monolithic modified release tablets comprising the sustained release granules as an internal phase and an immediate release formulation of a drug or drugs as an external phase. The drug release profile from either these granules or these tables may be adjusted by adjusting the percentages of the formulation's components. In one application, the disintegrating monolithic modified release tablets comprise amoxicillin and clavulanate and have a dissolution profile similar to brand and generic “Augmentin XR® Bilayered Extended Release Tablets (1000 mg/62.5 mg)”. The invention also relates to a method of preparing the foregoing sustained release granules.

Abstract: In an example of a method for three-dimensional (3D) printing, one or more dispersions is/are sprayed to form a layer including build material particles and a liquid agent. The liquid agent is evaporated from the layer to form a build material layer, and based on a 3D object model, a binder agent is applied on at least a portion of the build material layer.

Abstract: A burner includes a main body having an outer surface and at least partially defining an interior. The main body further includes an upstream end axially spaced from a downstream end. The outer surface includes a burner front face at the downstream end of the main body. An annular cooling air plenum is defined in the main body radially inwardly from the outer surface. A cooling air passage extends from the outer surface to the annular cooling air plenum. A plurality of cooling channels is circumferentially spaced apart from one another along the burner front face. Each cooling channel of the plurality of cooling channels extends from a respective inlet in fluid communication with the annular cooling air plenum to a respective outlet.

Abstract: The present invention discloses a method for preparing a full-body marble-patterned glass mosaic, comprising mixing a glass powder with an additive to obtain a mixture; adding water to the mixture and mixing thoroughly; granulating and sieving to obtain base clay body powder; mixing a colorant and a flux according to a specific ratio to obtain a colorant mixture in powder form; distributing the base clay body powder and the colorant mixture into multiple layers via a mold; press-molding to obtain a clay body; firing the clay body to obtain the full-body marble-patterned glass mosaic. Accordingly, the present invention provides a full-body marble-patterned glass mosaic prepared by the method described above. The glass mosaic of the present invention has a strong layering texture and a well-defined structure, and it faithfully resembles the pattern and texture of natural marble.

Abstract: According to an example, a three-dimensional (3D) printer may include a first delivery device to selectively deposit first liquid droplets onto a layer of build materials and a second delivery device to selectively deposit second liquid droplets onto the layer of build materials, in which the second delivery device is positioned in relatively close proximity to the first delivery device. The 3D printer may also include a controller to identify a density at which the second liquid droplets are to be selectively deposited to control splashing of the build materials upon which the second liquid droplets are deposited and to control the second delivery device to selectively deposit the second liquid droplets at the identified density.

Abstract: According to an example, an apparatus may include a recoater, an energy source, a carriage supporting the energy source, and a controller. The controller may control the recoater to spread build material particles into a layer on top of a previously applied layer containing fused build material particles and the carriage to move ahead of the recoater to cause the energy source to apply energy onto build material particles in the previously applied layer prior to the recoater spreading the build material particles onto the previously applied layer. The energy source is to heat the fused build material particles to or maintain the fused build material particles at a temperature above a certain temperature and the recoater is to be controlled to spread the build material particles on top of the previously applied layer prior to the fused build material particles falling below the certain temperature.

Abstract: A method of recycling build material powder including collecting in a keg an amount of excess build material powder during the additive manufacturing of a part cake. The part cake and keg are transferred to a de-powdering station. The part cake is de-powdered to release a mixture of reusable powder and contaminants. The mixture is sieved to remove the contaminants and deposit the reusable powder to the keg.

Abstract: A modular system for manufacturing includes a modular housing, at least one manufacturing platform disposed within the modular housing for direct digital manufacturing of an item, and a modular grid for power and network connections positioned along a plurality of interior walls of the modular housing.

Abstract: A method for producing pigments having a specified contour, comprises the steps of creating a pigment layer on a starting substrate; detaching from the starting substrate; and structuring the pigment layer into a plurality of the pigments; characterized by bringing into contact the pigment layer with an intermediate substrate, wherein the pigment layer adheres at least in sections to the intermediate substrate; and separating intermediate substrate and starting substrate.

Abstract: Tri- and tetra-saccharides are used in foods, beverages and other consumable products to mask or reduce the unpleasant taste of certain components also present in such products, such as the bitter taste of certain high intensity sweeteners. The organoleptic qualities of the products are thereby improved. In particular, melezitose, maltotriose and maltotetraose effectively reduce the bitterness of consumable products containing steviol glycosides such as rebaudioside A.

Abstract: The disclosed apparatus, systems and methods relate to sample preparation and shipping technologies in a single shippable container. The shipping container contains a single use centrifuge. The centrifuge can be temperature controlled and meets all standards and regulations for the shipping and transport of biological specimens.

Abstract: An apparatus for manufacturing a three-dimensional object by a layer-by-layer solidification of building material at the points corresponding to the cross-section of the object to be manufactured in a respective layer. The apparatus includes a process chamber in which the object is to be built up layer by layer by selectively solidifying layers of a building material in a build area, a gas supply device, and a recirculating air filter device, wherein the apparatus comprises a pressure stabilization device configured to keep the pressure in the process chamber substantially constant.

Abstract: A method that includes winding a composite fabric around a mandrel to form a plurality of layers defining an annulus extending along a central longitudinal axis, where the composite fabric includes a plurality of elongate axial fibers extending substantially in an axial direction relative to the longitudinal axis and a plurality of elongate circumferential fibers extending substantially in a circumferential direction relative to the longitudinal axis; and introducing, into at least a portion of the plurality of layers, a plurality of radial fibers extending substantially in the radial direction relative to the longitudinal axis, where the plurality of radial fibers mechanically bind one or more adjacent layers of the plurality of layers.

Abstract: The present invention relates to compressed bone-based products and methods to make the same. The maintained compressed state of the product serves to enhance the product's inherent osteoconductivity.

Abstract: In example implementations, a spreading blade is provided. The spreading blade includes a body portion, an ultrasonic vibration source, and a kicker. The ultrasonic vibration source is coupled to a top portion of the body portion to apply a vibration along a cross-sectional length of the body portion. The kicker is coupled to a side facing a process direction at a bottom end of the body portion. The kicker comprises a tip formed by a combination of two angled surfaces that extend from a lateral side of the body portion.

Abstract: Methods of manufacturing tissue interfacing components, such as solid needles comprising one or more therapeutic agents, are disclosed. In some embodiments, a method for manufacturing a tissue interfacing component comprises compressing a granular therapeutic agent within a mold cavity of a mold to form a solid tissue interfacing component. The mold cavity may define an elongated shape extending along a longitudinal axis from an opening of the mold cavity to a distal end of the mold cavity, and the granular therapeutic agent may be compressed by moving a mold punch along the longitudinal axis towards the distal end. After compressing the granular therapeutic agent to form the solid tissue interfacing component, the tissue interfacing component may be removed from the mold and subsequently inserted into tissue to deliver the therapeutic agent to a subject.

Abstract: A metal-powder and/or ceramic-powder press device includes at least one first punch (11) which, in a pressing position, is arranged to pass from a first side into a die opening, filled with ceramic and/or metal powder, of a die (13). At least one second punch (12), in the pressing position, is arranged to pass from a second side into the die opening, filled with ceramic and/or metal powder, of the die (13). A position measuring device determines a position of the first punch (11) and includes a first measuring element (16) and a second measuring element (19). The first measuring element (16) is connectable to the first punch (11) and the second measuring element (19) is connectable to the second punch (12), such that a relative position of the measuring elements to one another changes during the pressing operation. A sensor device determines the change in the relative position.

Abstract: A method for the treatment of residual thermoplastic powder from an additive manufacturing process includes, in one step of the process, a powder that includes the residual powder is provided and compressed into granules as raw material for a primary shaping process. A pressing apparatus with two roller elements rotating in opposite directions and having lateral surfaces adjacent to one another in a pressing area is used to compress the powder into the granules. The lateral surfaces each having a plurality of molding elements assigned to one another in pairs such that the powder is compressed into granules in the pressing area. A cam mechanism positioned within one of the roller elements and configured to deflect the plurality of molding elements radially as a function of an angle of rotation of the roller element can be included.

Abstract: A plane plate for a pressing tool of a press in which the plane plate activate a punch of the press by way of at least one lifting cylinder that can be displaced along an axial direction.

Abstract: A disclosed reinforcer includes a shrinkable layer able to shrink in a direction of shrinkage, under the effect of a heat-shrink heat treatment, from an initial state to a shrunk state, a first corrugatable layer, which includes a gridwork of filaments added against the shrinkable layer and connected to the shrinkable layer by connection lines spaced apart and extending transversely with respect to the direction of shrinkage, the first corrugatable layer exhibiting a shrinkage that is substantially zero or that is smaller than that of the shrinkable layer, so that, when the shrinkable layer is in the initial state, portions of the first corrugatable layer, each defined between two consecutive connection lines, are bent over and, when the shrinkable layer is in the shrunk state, the portions of the first corrugatable layer are curved.

Abstract: The present invention relates to pharmaceutical composition, comprising certain phosphate binder particles having a certain particle size distribution, a process for the manufacture of the pharmaceutical composition and the use of sucroferric oxyhydroxide having a certain particle size distribution for the manufacture of a pharmaceutical composition.

Abstract: The present invention relates to pharmaceutical composition, comprising certain phosphate binder particles having a certain particle size distribution, a process for the manufacture of the pharmaceutical composition and the use of sucroferric oxyhydroxide having a certain particle size distribution for the manufacture of a pharmaceutical composition.

Abstract: The present disclosure provides a method for producing a metal structure having holes dispersed in a matrix and having inorganic particles disposed inside the holes, that are capable of moving in the holes independently of the matrix, the method making it possible to increase the proportion of inorganic particles in the metal structure that are capable of moving in the holes independently of the matrix. In the method for producing a metal structure whereby inorganic particles are disposed inside holes dispersed in a matrix so as to be capable of moving independently of the matrix, the hollow particles covering the inorganic particles which are distributed in the matrix of the metal structure are fragmented so that the inorganic particles are disposed inside the holes formed by fragmenting the hollow particles.

Abstract: Various embodiments include a method for producing a gas diffusion electrode, the method comprising: providing a raw electrode layer comprising an electrically non-conducting web; adapting a thickness of the raw electrode layer; and applying a non-solvent to the raw electrode layer.

Abstract: A method of creating a soft and lofty continuous fiber nonwoven web is provided. The method includes providing two molten polymer components having different melting temperatures to a spinneret defining a plurality of orifices, and flowing a fluid intermediate the spinneret and a moving porous member. The moving porous member is positioned below the spinneret. The method includes using the fluid to draw or push the two molten polymer components, in a direction that is toward the moving porous member, through at least some of the plurality of orifices to form a plurality of individual bi-component continuous fiber strands. The method includes depositing the continuous fiber strands on the moving porous member at a first location to create an intermediate continuous fiber nonwoven web, and removing and/or diverting some of the fluid proximate to the first location to maintain loft and softness in the deposited intermediate continuous fiber nonwoven web.

Abstract: A method of producing a bioplastic granulate on the basis of sunflower seed shells or sunflower seed hulls. In the method, ground sunflower seed shells/sunflower seed hull material is provided, wherein the particle size is in the region of 3 mm or less, preferably in the region of 0.01 to 1 mm, preferably in the region of 0.1 to 0.3 mm. A plastic material is provided, which is compounded with the sunflower seed shells/sunflower seed hull material, wherein the compounding operation is preferably effected in an extruder, preferably a double-screw extruder. The compounded material is chopped at the end of the extruder section with a tool with the addition of water, wherein the water is at a temperature of preferably more than 50° C., preferably about 80 to 90° C., to cool down the compound material. During the compounding operation, the compounding material is subjected to atmospheric degassing and/or vacuum degassing.

Abstract: A fiber preform defining an annulus extending along a central longitudinal axis. The fiber preform includes a plurality of layers extending in an axial direction and a circumferential direction relative to the longitudinal axis. Each layer of the plurality of layers includes a plurality of elongate fibers. The plurality of elongate fibers include a plurality of elongate axial fibers extending substantially in the axial direction and a plurality of elongate circumferential fibers extending substantially in the circumferential direction. The fiber preform also includes a plurality of radial fibers extending substantially in the radial direction. The plurality of radial fibers mechanically bind one or more adjacent layers of the plurality of layers. At least 40% of the plurality of elongate fibers extend substantially in the axial direction.

Abstract: The invention is directed to a method and a device for the dosing of active substances for the preparation of medicaments. In the context of the dosing method, one or more active substances dissolved in a liquid are stored in a storage container, and, in order to permit dosing, a number of drops corresponding to the desired amount of active substance are forced actively through a nozzle onto a substrate or into a collecting vessel; the device used for this purpose comprises at least one storage container for storage of a liquid, and one or more active substances dissolved therein, and also a nozzle through which a number of drops corresponding to the desired amount of active substance are forced out onto a substrate or into a collecting vessel.

Abstract: A tooling inspection and analysis system measures tooling quality of a multi-tip tablet punch having a barrel with a plurality of tips each having a tip cup for forming a tablet. The system comprises a base. A carriage assembly has a cavity for supporting a multi-tip tablet punch, which when in use is aligned with an X-axis. A Y-axis linear slide mounts the carriage assembly to the base for movement relative to the base along a Y-axis. A sensor is adapted to measure distance. A Z-axis linear slide mounts the sensor to the base for movement relative to the base along a Z-axis. A programmable controller is operatively connected to the Y-axis linear slide, the Z-axis linear slide and the sensor. The controller is programmed to move the carriage assembly and the sensor to automatically align the sensor to measure working length of each tip of a multi-tip tablet punch mounted in the cavity.

Abstract: The invention comprises methods, systems, and devices for angular printing of slab-like inclined portions. Each printed portion overlaps the immediately preceding portion and in combination, the portions form a horizontal structure, such as a roof, floor, a formation of coupled slabs, and others. The horizontal structure may be designed based on desired shape and also based on the setting properties of the printing material. The inclined portions are strong enough to withstand the weight of the structure, so long as guidelines are followed for the required length of inclined portions based on the setting properties of the printing material. The strength of the resulting structure is maximized via the inclined structure making up each layer.

Abstract: Methods of making ceramic matrix prepregs are described. The methods include exposing a coated tow of ceramic fibers to a ceramic matrix slurry comprising a solvent and ceramic precursor. The coating is at least partially removed and the slurry infuses into the ceramic fibers to form prepreg. Steps to form ceramic matrix composites are also described, including forming the prepreg into a green body, and sintering the ceramic precursor.

Abstract: A three-dimensional (3D) part finishing system includes a submerging apparatus to receive a 3D printed part, and a liquid supply container to receive the submerging apparatus. The system further includes a controller operatively connected to the submerging apparatus. The controller is to receive or determine an input time for the 3D printed part and to control submersion of the submerging apparatus into the liquid supply container for the input time.

Abstract: The present invention relates to compositions, such as filled and coated papers, comprising microfibrillated cellulose and inorganic particulate material.

Abstract: Provided is a process for producing a graphene-based supercapacitor electrode from a supply of coke or coal powder, comprising: (a) exposing this powder to a supercritical fluid for a period of time in a pressure vessel to enable penetration of the supercritical fluid into internal structure of the coke or coal; wherein the powder is selected from petroleum coke, coal-derived coke, meso-phase coke, synthetic coke, leonardite, anthracite, lignite coal, bituminous coal, or natural coal mineral powder, or a combination thereof; (b) rapidly depressurizing the supercritical fluid at a fluid release rate sufficient for effecting exfoliation and separation of the coke or coal powder to produce isolated graphene sheets, which are dispersed in a liquid medium to produce a graphene suspension; and (c) shaping and drying the graphene suspension to form the supercapacitor electrode having a specific surface area greater than 200 m2/g.

Abstract: The present invention relates to a method for preparing high performance polymer-based conductive composites by space-limited micro-nano precision assembly method, which belongs to the technical field of composite material preparation; including the following steps: (1) through blending the conductive filler and the polymer matrix which are added to the blending equipment, homogeneous polymer/conductive filler material system is obtained; (2) add the homogeneous material system to the mold composed of two flat plates, and let the homogeneous blend gets plane limited compression by means of mechanical compression; (3) making use of the micro-nano structure array set on the compression template to further compact the filler on the network and conducting “array anchorage”, to realize the micro-nano precision assembly of network and obtain the composite material with excellent performance, which has a continuous and tight conductive network, and has excellent tensile properties, flexibility and thermal stability.

Abstract: A filler material is applied to a plurality of wood elements. The plurality of wood elements is bonded into a composite wood product, where the bonding includes delivering ultrasound energy to the plurality of wood elements. The ultrasound energy has a frequency within a frequency range of 10 kHz-20 MHz.

Abstract: A process for forming wood fibre comprising breaking down acetylated wood to produce acetylated wood fibre having a moisture content from about 5% w/w to about 8.5% w/w after it is comminuted to form wood fibre. The process includes a first moisture-introducing step for increasing the moisture content of the acetylated wood elements; and a second moisture-introducing step, separate to the first, for increasing the moisture content of the acetylated wood elements.

Abstract: A system for forming twisted or aligned electrospun fibers has been developed. The collector for the electrospun fibers is capable of rotation. In some instances, fibers are formed between two collectors, at least one of which rotates to twist the fibers into a multifilament bundle with increased strength. In a second embodiment, a cylindrical collector rotates, and charged polymer jet uniformly coats the surface of the collector. When a drum collector rotates at a high speed, electrospun fibers align and form an array. Optionally, different active agents can be included in the electrospinning solutions to form fiber constructs with different strengths and controlled release profiles, providing a reproducible method to generate complexed structures based on electrospun fibers and controlled drug delivery profiles.

Abstract: A single- or multiple-component composition, which forms upon mixing with water a (meth)acrylic hydrogel and which composition including at least one water soluble at room temperature liquid (meth)acrylic compound supported on a solid carrier and/or an aqueous solution of at least one at room temperature solid or liquid (meth)acrylic compound, a free-radical initiator, and optionally a catalyst for the initiator. A method produces a hydrogel. An acrylic injection material. A method seals cracks, voids, flaws and cavities in building structures.

Abstract: The particle impregnating device includes a placing body for placing a nonwoven fabric having a surface on which particles are sprayed; a vibrating member which is provided above the placing body and extends in the width direction of the nonwoven fabric placed on the placing body; a vibrator which applies ultrasonic vibration to the vibrating member; a lifting mechanism which lifts up and down the vibrating member; and a moving mechanism which relatively moves the nonwoven fabric and the vibrating member in a surface direction orthogonal to the width direction of the nonwoven fabric. When the nonwoven fabric and the vibrating member are relatively moved by the moving mechanism, the vibrating member is lowered by the lifting mechanism, so that the nonwoven fabric is pressed and compressed by the vibrating member and ultrasonic vibration is applied to the vibrating member by the vibrator.

Abstract: Alumina products containing a fine particle size component and a coarse particle size component, and with specific particle size characteristics and irregular and non-spherical particle shapes, are disclosed. These alumina products can be used in polymer formulations to produce composites having high isotropic thermal conductivity.

Abstract: Disclosed herein is a method of forming a multi-layered metallic part. The method comprises forming a plurality of ductile layers made of a metallic material having a first ductility. The method also comprises forming at least one high-strength powder layer made of a powdered metallic material having a second ductility higher than the first ductility. The method further comprises assembling the plurality of ductile layers and the at least one high-strength powder layer in an alternating and stacked formation to form a multi-layered metallic assembly. The method additionally comprises oscillating a crystallographic phase of the powdered metallic material of the at least one high-strength powder layer between a first crystallographic phase and a second crystallographic phase.