Abstract: A tamper-proof, point-of-collection specimen assay apparatus including three selectively connectable and sealable chambers, including a first chamber for receiving a specimen, a second chamber housing a specimen testing device and a specimen transfer site positioned between the first chamber and the second chamber for selectively depositing a portion of the specimen from the first chamber into the second chamber and a third chamber having inlets for depositing another portion of the specimen from the first chamber into the third chamber.

Abstract: A fluid sampling device (100) that operates by a combination of capillary action to collect a small fluid sample, and by pressure differential when inserted into an analyzer (200) to expose the fluid sample for testing by the analyzer (200). The device is especially suited for use as a disposable blood sampling unit designed to interface with a blood analyzer, albeit the concept of the invention may be employed for sampling and testing virtually any fluids.

Abstract: Embodiments of the present invention relate to a test strip container which provides easy access to test strips. The test strip container includes a lower housing, an upper housing, and a retaining member configured to releasably retain the test strips in a nested configuration. The nested configuration of the test strip container provides easy access to test strips by arranging the test strips so that they extend radially outward from the retaining member. The radial arrangement of the test strips operates to separate the test strips so that test strip users may easily select a single test strip from a plurality of test strips. Alternatively, the test strip container includes a lower housing, an upper housing, and a retaining member configured to releasably retain the test strips in a longitudinal configuration.

Abstract: The invention provides a system and method for dissolution testing. The system includes multiple dissolution vessels and a dose carrier positioned above the dissolution vessels. The dose carrier holds multiple removable carousels that receive individual doses for dissolution tested. Carousels that receive tablets or sinkers typically have a first configuration, while carousels that receive baskets typically have a second configuration. The two different configurations of carousels are interchangeable on the same dose ring. The system further includes a drive head positioned above the dose carrier, the drive head having a basket arbor and a mixing paddle removably and interchangeably attached. A pipettor integral with the system transfers sample aliquots having volumes in the range of 50 ?l to 1 ml from the dissolution vessels to wells of an external receptacle.

Abstract: A disposable cartridge adapted to be used with a sensor-dispensing instrument comprises a housing, test sensors, a mechanical mechanism and moveable seals. The housing forms at least one opening therethrough. The test sensors are stacked in the housing. The test sensors are adapted to assist in testing at least one analyte. The mechanical mechanism is adapted to urge the test sensors in a first direction. One of the test sensors is positioned for ejection from the cartridge. The moveable seals is adapted to be in a closed position that seals the at least one opening so as to provide a substantially moisture-proof and a substantially air-tight cartridge, and one of the moveable seals is adapted to be in an open position that allows one of the test sensors to be moved therethrough.

Abstract: According to one embodiment of the present invention, an optical-based test sensor for use in the determination of an analyte in a liquid sample is disclosed. The test sensor includes a base, a polymer carrier, and a test membrane. The base has a capillary channel formed in a surface of the base that is adapted to move a liquid sample from an inlet to a reaction area formed in the base. The polymer carrier has a lower surface adhered to the surface of the base and is disposed over at least a portion of the capillary channel. The test membrane, which contains a reagent, is adhered to the lower surface of the polymer carrier and extends from the polymer carrier into the reaction area.

Abstract: An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.

Abstract: In some aspects, analyte test strip dispensers are provided. In some aspects, the analyte test strip dispensers store a plurality of analyte test strips and dispense one or more analyte test strips when needed. The analyte test strips may be stacked with an analyte test strip at one of the stack engaged with a dispensing element. The dispensing element may be slid relative to the dispenser to displace the analyte test strip out of the dispenser. In some aspects, an elastomeric cap having strong barrier properties for water vapor and moisture is provided. The elastomeric cap may be undersized in relation to the dispenser and stretched to couple to the dispenser, thus providing a pressure-fit seal along with strong barrier properties to water vapor and moisture.

Abstract: An analyte testing device is provided for use with a mobile processing device having a camera with a lens, a processor for processing an image captured by the lens. The analyte testing device comprises a casing and a test strip positioner. The test strip positioner positions an analyte containing test strip adjacent to the camera lens to permit the camera to capture an image of the analyte containing test strip. A light source is disposed within the casing. The light source is positioned within the casing to illuminate the analyte containing test strip to facilitate the capture of the image of the test strip. Software is contained within the mobile processing device for performing a quantitative analysis of at least one analyte from the captured image, and providing an output of the results of the quantitative analysis.

Abstract: A test strip with a covering layer having a novel slot. The slot divides the inventive covering layer into two parts and provides a vent opening that allows air to escape as fluid enters a cavity or sample receiving chamber formed in the test strip. In preferred embodiments, the covering layer is clear such that the user can see through it and the slot doubles as a “fill line.” The user can thus watch the fluid sample enter the test strip, progress through the capillary cavity, and then stop at the slot or fill-line. This provides positive assurance to the user that the sample size is sufficient and the test strip has been filled properly. The present invention also provides an advantageous method of mass-producing the inventive test strips without having to align the slot or vent opening laterally with respect to the test strips and without having to punch a vent opening. The method is also well suited to mass production by roll processing techniques.

Abstract: A cartridge assembly is adapted to be used in a sensor-dispensing device. The cartridge assembly comprises an end cap, a disposable cartridge and a sealing mechanism. The end cap includes one opening. The disposable cartridge comprises an outer and inner cartridge. The inner cartridge contains sensors arranged in a stack therein. Each of the sensors carries a reagent sufficient to produce a signal in response to the analyte concentration in a fluid. The outer cartridge forms an opening of sufficient dimensions to permit a sensor to pass through the opening. The outer cartridge includes a holding mechanism that holds at least one of the sensors in place during movement of the inner cartridge. The sealing mechanism is adapted to form a substantially moisture-tight seal.

Abstract: A reagent management system for an automated biological reaction apparatus including an automated biological reaction apparatus including at least one reagent dispenser for applying a reagent to a sample, a memory device containing data for a reagent device selected from the group consisting of a reagent dispenser or a reagent kit used in the automated biological reaction apparatus, a host device comprising a processor and a host device memory connected to the processor, the host memory device including a reagent table, and a scanner for transferring the memory device data to the host device memory.

Abstract: A chemical indicating device (10) for detection of chloride ions in a sample is provided. The chemical indicating device (10) includes a carrier matrix (12) and an indicator (14) having silver and vanadate supported on the carrier matrix (12). A method for detecting chloride ions is also provided.

Abstract: In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements.

Abstract: Articles for testing a coagulation process in whole blood.

Abstract: A screening system and method are described herein which provide a unique and practical solution for enabling label-free high throughput screening (HTS) to aid in the discovery of new drugs. In one embodiment, the screening system enables direct binding assays to be performed in which a biomolecular interaction of a chemical compound (drug candidate) with a biomolecule (therapeutic target) can be detected using assay volumes and concentrations that are compatible with the current practices of HTS in the pharmaceutical industry. The screening system also enables the detection of bio-chemical interactions that occur in the wells of a microplate which incorporates biosensors and surface chemistry to immobilize the therapeutic target at the surface of the biosensors. The screening system also includes fluid handling and plate handling devices to help perform automated HTS assays.

Abstract: The invention relates to a heated reaction chamber for processing a biochip and to a method for controlling said reaction chamber. The heated reaction chamber for processing a biochip comprises a chamber wall, constituted by a flexible circuit board (10), a circuit path (10.3) being configured on the flexible circuit board (10) and being used as the heating device. The use of a flexible circuit board as the wall of a reaction chamber allows for a low thermal capacity of the reaction chamber in the area of the heating device, thereby allowing the chamber to be heated up quickly.

Abstract: The present invention relates, for example, to a stimulus-indicating device. More particularly, the present invention includes an apparatus for evidencing when a stimulus sensitive product has been exposed to a designated or predetermined stimulus for a certain period of time, and the invention further may include a method for manufacturing aspects of that apparatus.

Abstract: Methods and devices for rapid lateral flow immunoassays to detect specific antibodies within a liquid sample while also validating the adequacy of the liquid sample for the presence of immunoglobulin and the integrity and immunoreactivity of the test reagents that detect the antibodies of interest, without requiring instrumentation. The methods and devices provide for delivery of a diluted liquid sample to a single location that simultaneously directs the liquid flow along two or more separate flow paths, one that serves as a positive control to confirm that all critical reagents of the test are immunoreactive, and that the sample being tested is adequate, and the other to detect specific antibodies if present.

Abstract: Disclosed is an assay device for determining the presence and/or extent of one or more analytes in liquid sample containing a) first and second assays each comprising a flow-path having a detection zone for immobilising a labelled binding reagent, wherein detection of a labelled binding reagent at one or both detection zones is indicative of the presence and/or extent of one or more analytes; b) a shared reference zone; c) one or more light sources to illuminate the detection zones and the reference zone; d) one or more photodetectors to detect light from the detection zones and the reference zone, which photodetector/s generate a signal, the magnitude of which signal is related to the amount of light detected; and e) signal processing means for processing signals from the photodetector/s.

Abstract: An apparatus for positioning a cuvette in an optical beam path of an optical measuring instrument, with a shaft for axially inserting a cuvette, and means for pressing a cuvette against at least one wall surface of the shaft, which comprise at least one arrangement of a magnet, stationarily arranged with respect to the shaft, and a magnet movable with respect to the same, which are oriented such that the movable magnet tends to occupy a certain position with respect to the stationary magnet, in which the movable magnet engages at least partially into the shaft.

Abstract: Microfluidic sample processing disks with a plurality of fluid structures formed therein are disclosed. Each of the fluid structures preferably includes an input well and one or more process chambers connected to the input well by one or more delivery channels. The process chambers may be arranged in a compliant annular processing ring that is adapted to conform to the shape of an underlying thermal transfer surface under pressure. That compliance may be delivered in the disks of the present invention by locating the process chambers in an annular processing ring in which a majority of the volume is occupied by the process chambers. Compliance within the annular processing ring may alternatively be provided by a composite structure within the annular processing ring that includes covers attached to a body using pressure sensitive adhesive.

Abstract: A sample acquiring device for volumetric enumeration of white blood cells in a blood sample comprises a measurement cavity for receiving a blood sample. The measurement cavity has a predetermined fixed thickness. The sample acquiring device further comprises a reagent, which is arranged in a dried form on a surface defining the measurement cavity. The reagent comprises a hemolysing agent for lysing red blood cells in the blood sample, and a staining agent for selectively staining white blood cells in the blood sample. A system comprises the sample acquiring device and a measurement apparatus. The measurement apparatus comprises a sample acquiring device holder, a light source, and an imaging system for acquiring a digital image of a magnification of the sample. The measurement apparatus further comprises an image analyser arranged to analyse the acquired digital image for determining the number of white blood cells in the blood sample.

Abstract: A vessel (102) containing a detector solution (101) is prepared. The detector solution (101) is an aqueous solution prepared by dissolving a detector component containing a dye which changes its color when reacting with ozone gas, a humectant, and an ultraviolet absorber having a hydrophilic group. A prepared sheet-like carrier (103) is dipped in the detector solution (101) for, e.g., 30 sec, thereby forming an impregnated sheet (104) by impregnating the sheet-like carrier (103) with the detector solution (101). The impregnated sheet (104) is then dried by evaporating the solvent (medium) such as water contained in the impregnated sheet (104), thereby forming a sheet-like ozone detecting device (105).

Abstract: A bioassay substrate and method thereof is provide. In the bioassay substrate, a sample solution is dripped onto a spot area to which a plurality of detection substances is fixed and an interaction between the detection substance and a target substance in the sample solution is detected by fluorescent intensity. The substrate includes: a predetermined number of the spot areas placed in a well arranged on the surface of the substrate; and a fine uneven structure continuously formed on a bottom surface configuring the spot areas.

Abstract: Methods and apparatus for chemical warfare agent detection training are provided. More particularly, methods and apparatus are provided to simulate the detection of low volatility chemical warfare agents by simulating the use of currently fielded U.S. Army detection kits without exposure to hazardous agents. A simulant is disposed in a sample heating assembly. The sample heating assembly is placed over a detection window of a detector, and the simulant is heated in order to make a simulated detection.

Abstract: A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to “target” with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.

Abstract: The present invention relates to test devices, and in particular devices capable of detecting the presence or absence of an analyte in a sample, such as a liquid sample. Also provided are methods of using such devices for quantitative or qualitative measurement of one or more analytes in a liquid sample.

Abstract: Embodiments of the present invention relate to a test strip container which provides easy access to test strips. The test strip container includes a lower housing, an upper housing, and a retaining member configured to releasably retain the test strips in a nested configuration. The nested configuration of the test strip container provides easy access to test strips by arranging the test strips so that they extend radially outward from the retaining member. The radial arrangement of the test strips operates to separate the test strips so that test strip users may easily select a single test strip from a plurality of test strips. Alternatively, the test strip container includes a lower housing, an upper housing, and a retaining member configured to releasably retain the test strips in a longitudinal configuration.

Abstract: A method and apparatus for use in a flow through assay process is disclosed. The method is characterised by a “pre-incubation step” in which the sample which is to be analyzed (typically for the presence of a particular protein), and a detection analyte (typically one or more antibodies bound to colloidal gold or a fluorescent tag) which is known to bind to the particular protein may bind together for a desired period of time. This pre-incubation step occurs before the mixture of sample and detection analyte come into contact with a capture analyte bound to a membrane. The provision of the pre-incubation step has the effect of both improving the sensitivity of the assay and reducing the volume of sample required for an assay. An apparatus for carrying out the method is disclosed defining a pre-incubation chamber for receiving the sample and detection analyte having a base defined by a membrane and a second membrane to which a capture analyte is bound.

Abstract: The present invention provides devices, methods, and kits for the collection of a solid or semi-solid sample and analysis for the presence, absence, or quantity of an analyte. The invention provides a collection slide having a first card and a second card. The first card has a sample collection area. The first and second cards have orifices allowing the passage of fluid through the sample collection area, and the cards are hingeably connected to each other. The invention also provides an assay device having a housing with a test element, a results window, and a docking area for receiving and engaging the collection slide. In one embodiment the collection slide and device can be used to detect the presence of fecal occult blood (human hemoglobin) in a stool sample. Many other embodiments are described herein.

Abstract: A device for separating and drying a fluid sample in one embodiment includes an upper layer including a sample window and a viewing window extending therethrough, the viewing window spaced apart from the sample window, an absorbent layer, having a width and a length, positioned beneath the upper layer and extending beneath the sample window and the viewing window, and a non-absorbent layer positioned beneath the absorbent layer, the non-absorbent layer having a width and a length greater than the width and the length of the absorbent layer.

Abstract: A test strip ejection mechanism, for use with a test strip receiving port and a test strip, includes a framework, an elongated shape memory alloy (SMA) strip (e.g., a SMA wire), a slider, and a heating module. The SMA strip has first and second ends that are attached to the framework and exhibits a solid state transition temperature. The slider is configured to travel along the framework. The heating module is configured to heat the SMA strip from a temperature below the solid state transition temperature to a temperature above the solid state transition temperature. Moreover, the SMA strip and slider are configured such that the slider travels along the framework under an applied force exerted on the slider by the SMA strip as the shape memory strip is heated from a temperature below the solid state transition temperature to a temperature above the solid state temperature by the heating module.

Abstract: A method for analyzing formation fluid in earth formation surrounding a borehole includes storing analytical reagent in a reagent container in a fluids analyzer in a formation tester and moving the formation tester, including the reagent, downhole. Reagent from the reagent container is injected into formation fluid in the flow-line to make a mixture of formation fluid and reagent. The mixture is moved through a spectral analyzer cell in the fluids analyzer to produce a time-series of optical density measurements at a plurality of wavelengths. A characteristic of formation fluid is determined by spectral analysis of the time-series of optical density measurements.

Abstract: An immunodiagnostic test card includes a plurality of transparent chambers wherein each chamber includes a quantity of testing material that combines with a patient sample, when mixed, to produce an agglutination reaction. A plurality of indicia are disposed to aid in the manufacture and determining the usability of the cards prior to test and also in objectively grading the agglutination reactions that are formed or lack of agglutination.

Abstract: A compact biosensor cartridge in which biosensors can be set with simple operation so that they can be tested one by one, and which protects the biosensors from moisture until they are set. A biosensor dispensing device is also disclosed. A biosensor cartridge (6) to be installed in a biosensor dispensing device (1) includes a pushing member (31) and a pushing rotating member (34) both used for ejecting biosensors (10) stacked in a case one by one and ejecting each sensor (10) through a sensor ejecting port (26). This structure presents the biosensor cartridge (6) to be made small and thin.

Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.

Abstract: The present invention is drawn toward a chemical or biological sensor that can comprise a semi-conducting nanowire and a chemical or biological sensing molecule tethered to the semi-conducting nanowire through a spacer group including a hydrophilic reactive group. In one embodiment, the semi-conducting nanowire can be part of an array of like or similar semi-conducting nanowires. Electrical leads can provide an electrical current to the array, and a signal measurement apparatus can be electrically coupled to the array, and can be configured for detecting changes in the electrical current of the array.

Abstract: An apparatus for detecting exposure to at least one hazardous substance is provided. The apparatus includes a body having a plurality of openings, and an attachment mechanism coupled to the body. Each opening is sized to receive a cassette for detecting the presence or absence of at least one hazardous substance. The cassette can include a colorimetric sensor having a base layer fabricated from a hydrophobic film, a colorimetric coating for covering the hydrophobic film, and at least one hydrophobic membrane for controlling the exposure of the specific substance to the colorimetric coating.

Abstract: A device for studying individual cells including a picowell array (such as an array of microwells, dimples, depressions, tubes or enclosures) and a fluid reservoir in fluid communication with the picowells through channels is disclosed. Preferably, the device has a moveable lid that in one rest location allows loading of cells in the picowell array. Preferably the channels of the device are capillary channels. Also disclosed is a device for the automated study of cells including a picowell-bearing device having a picowell array with a moveable lid, a lid-moving component, at least one solution dispensing component and a control system functionally associated with the lid-moving component as well as with the solution dispensing component.

Abstract: Ellipsometry systems for imaging binding events between analytes in a sample and an array of ligands in an evanescent field generated by a beam of light reflected from the plane of the ligands is adapted to a multiwell plate structure in common use. In one example, a film of prism arrays is affixed to the underside of the plate with each prism array located in registry with a well and ligand arrays being immobilized on the (planar) bottom surface of the wells. The prism array may be formed in a film and juxtaposed with the bottom surface of the plate or a prism array can be made integral with the plate bottom of a multiwell plate.

Abstract: The present invention relates to a diagnostic kit and more specifically to a self contained diagnostic kit providing analysis of a sample by a sample collectin element and an immunochromatography test strip.

Abstract: An oral fluid collection and transfer device comprises a collection device (10) and a test cartridge (100). The collection device includes a frame or chassis (14), and an absorbing pad (12) for absorbing oral fluid and which is secured around part of the frame with part of the frame protruding from the pad. A collapsible cover (16) covers the absorbing means and has apertures (68) for the ingress of oral fluid into contact with the absorbing pad. A cap (18) covers the part of the frame protruding from the absorbing pad. The cap and the cover latch together to surround the frame and the absorbing pad. The device also includes a fluid adequacy indicator (20) in the form of an electrical circuit with an LED (66) which is completed when the absorbing means has absorbed a predetermined volume of oral fluid.

Abstract: An improved rapid diagnostic device, assay and multifunctional buffer reagent are provided for the detection of a target analyte in a fluid test sample. The 2-step assay utilizes a dual component flow-through device comprising a test unit and a dried indicator reagent delivery unit capable of receiving the fluid sample and multifunctional buffer, respectively. The test unit comprises a reaction zone containing immobilized capture reagent that can specifically bind to the target analyte, an absorbent zone supporting the reaction zone, and optionally, a blood separation zone in lateral fluid communication with the reaction zone. The dried indicator reagent delivery unit comprises a label zone permeated with a dried indicator reagent which is capable of being placed in transient fluid communication with the reaction zone of the test unit during the assay procedure.

Abstract: A hydrogen sensor includes a thin film layer formed on a top surface of a planar optical transmission medium, and a catalyst layer formed on a top surface of the thin film layer. A first interface is created between the planar optical transmission medium and the thin film layer. A substrate is joined to a bottom surface of the planar optical transmission medium so that a second interface is created between the planar optical transmission medium and the substrate. On entering a first end portion of the planer optical transmission medium, light from a light source is spread by an entrance section, and the spread light is transmitted inside the planar optical transmission medium to a second end portion by being reflected by the first and second interfaces alternately. Light exiting from the second end portion is transmitted to an optical sensor by an exit light-collecting section.

Abstract: Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods permit selective sensitization of the discrete sensing areas, and provide selective contact of the discrete sensing areas with a sample fluid flow. Immobilization of a ligand upon the discrete sensing area, followed by selective contact with an analyte contained within the sample fluid flow, allows analysis by a wide variety of techniques. Sensitized sensing surfaces, and sensor devices and systems are also provided.

Abstract: An apparatus, system and method for verifying the achievement of a desired sterility assurance level (SAL) for components manipulated within a low-energy electron beam sterilization chamber. The components are preferably pre-sterilized and connected together in an assembly fashion which creates and maintains the sterility of the connection by subjecting the components to low-energy (less than 300 KeV) electron beam radiation. The verification is completed by measuring the sterilization dose delivered to a sensor, also known as a dosimeter, positioned within the sterilization process to simulate the components.

Abstract: Disclosed herein is a reference electrode including an electrolyte containing an optically-active material, including: an electrode body provided at an end thereof with an electrolyte separation membrane and charged therein with an optically-active material and an electrolyte solution; an inner electrode disposed in the electrode body to be immersed in the electrolyte solution; and an absorbance measurement probe for transmitting light to the electrolyte solution and collecting reflected light waves, which is disposed in the electrode body to be immersed in the electrolyte solution. Since the concentration of an electrode reaction material, such as Cl?, in the electrolyte is calculated using the absorbance of the electrolyte solution containing the optically-active material, the change in potential of the reference electrode can be properly corrected even when the reference electrode is exposed to a test environment for a long period of time and thus the concentration of the electrolyte changes.

Abstract: A tube and float system for use in separation and axial expansion of the buffy coat is provided. The system includes a transparent, or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The sample tube has an elongated sidewall having a first cross-sectional inner diameter. The float consists of a main body portion and one or more support members protruding from the main body portion to engage and support the sidewall of the sample tube. The main body portion and the support members of the float have a cross-sectional diameter less than that of the first cross-sectional inner diameter of the tube when the sample tube is expanded, such as by centrifugation. The main body portion of the float together with an axially aligned portion of the sidewall define an annular volume therebetween.

Abstract: Devices and methods for the detection of antigens are disclosed. Devices and methods for detecting food-borne pathogens are disclosed.