Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
Type:
Application
Filed:
January 28, 2015
Publication date:
May 21, 2015
Applicant:
EVONIK DEGUSSA GMBH
Inventors:
ALEXANDER RETH, BRIGITTE BATHE, STEPHAN HANS, WILFRIED CLAES
Abstract: The present invention provides a fed-batch culture method comprising a step of fed-batch-feeding a carbon source base and a base in such a manner that the pH level can be maintained at a level suitable for the growth of microorganisms for fermentation of a carbon source. The present invention also provides a method for preparing organic acids using the fed-batch culture method. The present invention fed-batch-feeds a neutralizing agent such as ammonium bicarbonate, ammonium carbonate or alkali metal-containing weak base, and a carbon source substrate in preparing organic acids by microorganism fermentation. Thus, a pH level suitable for the survival of microorganisms for carbon source fermentation can be maintained, and the speed of injecting the carbon source base which is the source material can be appropriately adjusted.
Type:
Application
Filed:
May 21, 2013
Publication date:
May 21, 2015
Inventors:
Jae Yeon Park, Sin Young Kang, Woo Chan Park, Min Su Koo, In Ho Cho, Joong Min Park, Seung Yeop Lee, Dong Hyun Kim
Abstract: A method of producing a sugar liquid from cellulose-containing biomass includes (1) to (4): (1) subjecting a cellulose-containing biomass to a dilute sulfuric acid treatment and thereafter separating the treated cellulose-containing biomass into a dilute sulfuric acid-treated liquid and a cellulose-containing solid content; (2) adding a cellulase to the cellulose-containing solid content to hydrolyze the cellulose and thereafter obtaining a sugar liquid; (3) filtering the dilute sulfuric acid-treated liquid through a nanofiltration membrane at pH 2.5 or lower to thereby separate a sugar concentrated liquid as a retentate and at the same time recover a sulfuric acid aqueous solution as a permeate; and (4) reusing the whole amount or a part of the sulfuric acid aqueous solution obtained in (3) in the dilute sulfuric acid treatment in (1).
Abstract: Provided herein are transgenic plants that include increased expression of a coding region encoding a PAE poly-peptide compared to a control plant. In one embodiment, a transgenic plant includes a phenotype of decreased recalcitrance, increased growth, or the combination thereof. Also provided herein are methods for generating transgenic plants, and methods for using transgenic plants. Examples of methods for using transgenic plants include, for instance, processing a transgenic plant described herein to result in a processed pulp, and exposing a plant material obtained from a plant described herein to conditions suitable for the production of a metabolic product.
Abstract: This disclosure describes, generally, recombinant cells modified to exhibit increased biosynthesis of pentanoic acid, methods of making such recombinant cells, and methods of inducing the cells to produce pentanoic acid. This disclosure also describes, generally, recombinant cells modified to exhibit increased biosynthesis of 2-methylbutyric acid, methods of making such recombinant cells, and methods of inducing the cells to produce 2-methylbutyric acid.
Abstract: Provided are isolated polypeptides having glucoamylase activity, catalytic domains, and polynucleotides encoding the polypeptides, catalytic domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains.
Abstract: The present invention relates to methods of degrading or converting biomass material enriched with hemicellulosic material into fermentable sugars.
Type:
Application
Filed:
January 14, 2015
Publication date:
May 7, 2015
Inventors:
Prashant Iyer, Harry Showmaker, Hui Xu, Kishore Rane
Abstract: The invention provides a process for the preparation of hydrocarbons substituted with at least one group containing at least one oxygen atom, comprising the process steps A) reaction of a carbon source comprising at least one selected from CO2 and CO to give acetate and/or ethanol with a first microorganism, B) separating off of the acetate from the first microorganism, C) reaction of the acetate to give a hydrocarbon substituted with at least one group containing at least one oxygen atom with a second microorganism and optionally D) purification of the hydrocarbon substituted with at least one group containing at least one oxygen atom.
Abstract: The present invention relates to a concentrated extract of cranberry (Vaccinium macrocarpon), the complex composition of which makes it possible to increase the antibacterial effects thereof, which is of use for the prevention or treatment of urinary infections, and in particular for the preventive treatment of urinary infections or treatment against the recurrence thereof. The invention also relates to a process for preparing such an extract, to food, nutraceutical or pharmaceutical compositions comprising the extract and to the use thereof in the treatment or prevention of urinary infections.
Type:
Application
Filed:
June 7, 2013
Publication date:
May 7, 2015
Inventors:
Philippe Sanoner, Valerie Bochard, Lucie Charissou, Benedicte Lastique, Morgane Jacob, Patrice Thomas
Abstract: The present invention provides fungal xylanase and/or xylosidase enzymes suitable for use in saccharification reactions. The present invention provides xylanase and xylosidase enzymes suitable for use in saccharification reactions. The present application further provides genetically modified fungal organisms that produce xylanase(s) and/or xylosidase(s), as well as enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to fermentable sugars, enzyme mixtures produced by the genetically modified fungal organisms, and methods for producing fermentable sugars from cellulose using such enzyme mixtures. In some embodiments, the xylanase and xylosidase enzyme(s) are M. thermophila enzymes.
Type:
Application
Filed:
January 14, 2015
Publication date:
May 7, 2015
Inventors:
Nicholas John Agard, David Elgart, Jie Yang, Goutami Banerjee, Jeanne Bonomo Benoit, Dipnath Baidyaroy
Abstract: The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.
Type:
Grant
Filed:
January 8, 2014
Date of Patent:
May 5, 2015
Assignee:
BASF SE
Inventors:
Hartwig Schröder, Stefan Haefner, Gregory Von Abendroth, Rajan Hollmann, Aline Raddatz, Hansgeorg Ernst, Hans Gurski
Abstract: The present invention provides a composition, such as a food and pharmaceutical agent, which comprises dihomo-?-linolenic acid, and which has the effect of preventing or treating skin diseases; a composition such as a food and pharmaceutical agent which comprises dihomo-?-linolenic acid and which has the effect of preventing or treating skin diseases; and a composition which comprises dihomo-?-linolenic acid and which has the effect of preventing or treating diseases related to increased mast cell count.
Abstract: The invention relates to genetically engineered Candida tropicalis cells, use thereof and a method of production of ?-hydroxycarboxylic acids and ?-hydroxycarboxylic acid esters.
Type:
Grant
Filed:
February 12, 2013
Date of Patent:
April 7, 2015
Assignee:
Evonik Degussa GmbH
Inventors:
Markus Poetter, Hans-Georg Hennemann, Steffen Schaffer, Thomas Haas
Abstract: A genetically engineered yeast cell that produces a pyruvate-based metabolite from pyruvate, wherein activity of a mitochondrial pyruvate carrier (MPC) is reduced compared to a parent yeast cell and a method of producing the pyruvate-based metabolite using the yeast cell.
Type:
Application
Filed:
July 21, 2014
Publication date:
March 26, 2015
Inventors:
Young-kyoung PARK, Chang-duk Kang, Ji-yoon Song, Ju-young Lee, Seung-hyun Lee, Kwang-myung Cho
Abstract: The invention relates to recombinant expression of variant forms of M. thermophila CBH1a and homologs thereof, having improved thermoactivity, specific activity, and other desirable properties. Also provided are methods for producing ethanol and other valuable organic compounds by combining cellobiohydrolase variants with cellulosic materials.
Type:
Application
Filed:
March 12, 2013
Publication date:
March 26, 2015
Inventors:
Behnaz Behrouzian, Xinkai Xie, Kui Chan, Xiyun Zhang, Vesna Mitchell, Douglas A. Hattendorf
Abstract: Provided herein is an alkane-metabolizing cell that is unable to convert propionyl-CoA into methylmalonyl-CoA or 2-metylcitrate synthase. Depending on which enzymes are present in the cell, the cell can produce acrylate or a precursor for the same (e.g., propionate, 3-hydroxypropionyl-CoA, 3-hydroxypropionate, acrylyl-CoA) that can be readily converted to acrylate enzymatically (e.g., in the cell) or by chemical treatment. In one embodiment, the cell may contain a cytochrome P450 or alkane oxidase enzyme that allows the production of 3-hydroxypropionyl-CoA, which can be readily converted to 3-hydroxypropionate. In order to make such compounds, the cell may be grown in the presence of an odd-numbered chain alkane (e.g., pentane or heptane), although another odd-numbered chain alkane may be used. In another embodiment, the cell may contain acyl-CoA oxidase, enoyl-CoA hydratase, and hydrolase.
Type:
Application
Filed:
October 17, 2012
Publication date:
March 26, 2015
Inventors:
Joshua A. Silverman, Tom Purcell, Jon Edward Ness, Effendi Leonard
Abstract: The present invention relates to methods of processing lignocellulosic material to obtain hemicellulose sugars, cellulose sugars, lignin, cellulose and other high-value products. Also provided are hemicellulose sugars, cellulose sugars, lignin, cellulose, and other high-value products.
Type:
Application
Filed:
May 3, 2013
Publication date:
March 26, 2015
Inventors:
Robert Jansen, Claire Gregoire, philip Travisano, Lee Madsen, Neta Matis, Yael Har-Tal, Shay Eliahu, James Alan Lawson, Noa Lapidot, Luke Burke, Aharon M. Eyal, Timothy Allen Bauer, Hagit Sade, Paul Mcwilliams, Ziv-Vladimir Belman, Bassem Hallac, Michael Zviely, Yelena Gershinksy, Adam Carden
Abstract: The present invention relates to a process for enzymatic hydrolysis of granular starch into a soluble starch hydrolysate at a temperature below the initial gelatinization temperature of said granular starch.
Type:
Application
Filed:
November 21, 2014
Publication date:
March 19, 2015
Inventors:
Anders Vikso-Nielsen, Carsten Andersen, Sven Pedersen, Carsten Hjort
Abstract: The invention relates to processes of producing a fermentation product, comprising liquefying a starch containing material with an alpha-amylase; pre-saccharifying and/or saccharifying and fermenting using a fermentation organism in the presence of a carbohydrate source generating enzyme and a cellulolytic composition The invention also relates to methods of dewatering whole stillage.
Type:
Application
Filed:
March 28, 2013
Publication date:
March 19, 2015
Inventors:
Thomas Rasmussen, Jeremy Saunders, James Croonenberghs, Zhengfang Kang, Joyce Craig, Michael John Akerman
Abstract: The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy) phosphonate (2H3M40P) pathway, p-toluate pathway, and/or terephthalate pathway. The invention additionally provides methods of using such organisms to produce 2H3M40P, p-toluate or terephthalate. Also provided herein are processes for isolating bio-based aromatic carboxylic acid, in particular, p-toluic acid or terephthalic acid, from a culture medium, wherein the processes involve contacting the culture medium with sufficient carbon dioxide (C02) to lower the pH of the culture medium to produce a precipitate comprised of the aromatic carboxylic acid.
Type:
Application
Filed:
January 18, 2013
Publication date:
March 19, 2015
Applicant:
Genomatica, Inc.
Inventors:
Robin E. Osterhout, Anthony P. Burgard, Mark J. Burk
Abstract: The present invention pertains to a fermentation process for the production of an organic acid salt including the steps of fermenting a microorganism in a fermentation medium in a fermentation reactor to form a fermentation broth having an organic acid salt, wherein part of the organic acid salt is present in the solid state and part of the organic acid salt is dissolved in the fermentation broth; withdrawing at least part of the fermentation broth from the fermentation reactor, providing the broth to a hydrocyclone, and withdrawing a top effluent and a bottom effluent from the hydrocyclone; providing the bottom effluent from the hydocyclone to a solid/liquid separation step, to form a solid fraction and a liquid fraction, providing at least 30 vol.% of the total of the top effluent from the hydrocyclone and the liquid fraction from the solid-liquid separation step to the fermentation reactor.
Type:
Application
Filed:
April 24, 2013
Publication date:
March 19, 2015
Inventors:
Jan Van Krieken, Adriaan Dirk Kon, André Banier De Haan, Frederik Gerrit Jan Kool
Abstract: The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Type:
Application
Filed:
April 26, 2013
Publication date:
March 19, 2015
Inventors:
Janine Lin, Doreen Bohan, Michelle Maranta, Leslie Beresford, Michael Lamsa, Matt Sweeney, Mark Wogulis, Elizabeth Znameroski, Frank Winther Rasmussen
Abstract: The invention relates to the use of a protein homologous to a MeaB protein for increasing the enzymatic activity of a 3-hydroxycarboxylic acid-CoA mutase, a fusion protein comprising a 3-hydroxycarboxylic acid-CoA mutase and a protein sequence homologous to a MeaB protein and an enzymatic method for producing 2-hydroxyisobutryric acid.
Type:
Grant
Filed:
October 11, 2010
Date of Patent:
March 17, 2015
Assignee:
Evonik Roehm GmbH
Inventors:
Liv Reinecke, Steffen Schaffer, Tim Koehler, Anja Thiessenhusen, Achim Marx, Markus Buchhaupt
Abstract: The present invention provides fungal xylanase and/or beta-xylosidase enzymes suitable for use in saccharification reactions. The present application further provides genetically modified fungal organisms that produce xylanase and/or beta-xylosidases, as well as enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to fermentable sugars, enzyme mixtures produced by the genetically modified fungal organisms, and methods for producing fermentable sugars from cellulose using such enzyme mixtures.
Type:
Grant
Filed:
June 10, 2013
Date of Patent:
March 17, 2015
Assignee:
Codexis, Inc.
Inventors:
Ryan Fong, Xiyun Zhang, Chris Noriega, Nicholas Agard, Anupam Gohel, Derek Smith
Abstract: A bacterium belonging to the genus Streptomyces having an ability to produce reveromycin A or a synthetic intermediate thereof, the bacterium being modified so as to increase expression of revQ gene coding for the amino acid sequence of SEQ ID NO: 36 or an amino acid sequence having an identity of not less than 80% to SEQ ID NO: 36 as compared with a parent strain, thereby the above-mentioned production ability is increased as compared with the parent strain.
Abstract: To provide a method for producing an organic acid, whereby the desired organic acid can be efficiently recovered without necessity for adjusting the pH to a neutral level in the fermentation step. The method for producing an organic acid, comprises a first step of producing an organic acid by fermentation to obtain a crude liquid containing the organic acid and having a pH of from 1 to 5, and a second step of extracting the organic acid from the crude liquid containing the organic acid obtained in the first step by means of an extraction medium containing a C10-30 diester compound and an alkylamine compound to obtain an extract (1).
Abstract: The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
Type:
Application
Filed:
March 17, 2014
Publication date:
February 26, 2015
Inventors:
Hans LIAO, Christopher Patrick MERCOGLIANO, Travis Robert WOLTER, Michael Tai Man LOUIE, Wendy Kathleen RIBBLE, Tanya LIPSCOMB, Eileen Colie SPINDLER, Michael D. LYNCH
Abstract: The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products.
Type:
Application
Filed:
March 17, 2014
Publication date:
February 26, 2015
Inventors:
Hans LIAO, Christopher Patrick MERCOGLIANO, Travis Robert WOLTER, Michael Tai Man LOUIE, Wendy Kathleen RIBBLE, Tanya LIPSCOMB, Eileen Colie SPINDLER, Michael D LYNCH
Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
Type:
Application
Filed:
November 4, 2014
Publication date:
February 26, 2015
Applicant:
Evonik Degussa GmbH
Inventors:
Alexander RETH, Brigitte Bathe, Stephan Hans, Wilfried Claes
Abstract: The present disclosure relates to an improved process of producing a fermentation product, in particular ethanol. The present disclosure relates also to the use of enzymes for improving the quality of by-products in the fermentative production process and to compositions comprising enzymes capable of degrading components in the fermented mash in the fermentation process.
Type:
Grant
Filed:
December 21, 2011
Date of Patent:
February 24, 2015
Assignee:
Direvo Industrial Biotechnology GmbH
Inventors:
Klaudija Milos, Steffen Köhler, Christian Elend, Léonie Degener
Abstract: The present invention provides various GH61 protein variants comprising various amino acid substitutions. The GH61 protein variants have an improved ability to synergize with cellulase enzymes, thereby increasing the yield of fermentable sugars obtained by saccharification of biomass. In some embodiments, sugars obtained from saccharification are fermented to produce numerous end-products, including but not limited to alcohol.
Type:
Grant
Filed:
August 22, 2012
Date of Patent:
February 10, 2015
Assignee:
Codexis, Inc.
Inventors:
Jie Yang, Xiyun Zhang, Jungjoo Yoon, Kripa Rao, John H. Grate, David Elgart, Dipnath Baidyaroy
Abstract: The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as sugars, alcohols, chemicals, amino acids, polymers, fatty acids and their derivatives, hydrocarbons, isoprenoids, and intermediates thereof, in organisms such that these organisms efficiently convert inorganic carbon to organic carbon-based products of interest using inorganic energy, such as formate, and in particular the use of organisms for the commercial production of various carbon-based products of interest.
Type:
Application
Filed:
October 30, 2012
Publication date:
February 5, 2015
Inventors:
Curt R. Fischer, Austin J. Che, Reshma P. Shetty, Jason R. Kelly
Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
Type:
Application
Filed:
October 20, 2014
Publication date:
February 5, 2015
Inventors:
Suchindra Maiyuran, Randall Kramer, Paul Harris
Abstract: The present invention relates to a method for producing a product of a reaction catalysed by a nitrilase, which method comprises the steps (i) providing a microorganism comprising said nitrilase located on its surface, and/or a membrane preparation of said microorganism, and (ii) contacting the microorganism and/or the membrane preparation thereof with one or more nitrilase substrates under conditions compatible with nitrilase activity. The present invention further relates to a method for producing enantiomerically pure (R)-mandelic acid using the nitrilase-displaying whole cell biocatalyst or membrane preparation thereof for the conversion of racemic mandelonitrile.
Type:
Grant
Filed:
November 16, 2010
Date of Patent:
February 3, 2015
Assignee:
Zyrus Beteiligungsgesellschaft mbH & Co. Patente I KG
Inventors:
Joachim Jose, Ruth Maas, Christian Detzel
Abstract: An object of the present invention is to provide a production process of an ?-hydroxy acid having a sufficient quality as a polymer raw material, which process does not produce a large amount of waste as a byproduct and is economical. The present invention provides a production process of an ?-hydroxy acid having a step of adding a basic metal to an ?-hydroxy acid ammonium salt to yield an ?-hydroxy acid metal salt and a step of desalting the ?-hydroxy acid metal salt to yield the ?-hydroxy acid.
Abstract: The invention provides non-naturally occurring microbial organisms containing caprolactone pathways having at least one exogenous nucleic acid encoding a butadiene pathway enzyme expressed in a sufficient amount to produce caprolactone. The invention additionally provides methods of using such microbial organisms to produce caprolactone by culturing a non-naturally occurring microbial organism containing caprolactone pathways as described herein under conditions and for a sufficient period of time to produce caprolactone.
Type:
Grant
Filed:
November 2, 2012
Date of Patent:
January 27, 2015
Assignee:
Genomatica, Inc.
Inventors:
Anthony P. Burgard, Robin E. Osterhout, Priti Pharkya, Mark J. Burk
Abstract: The invention relates to a method and a system for the pretreatment of lignocellulosic material by thermal hydrolysis, in particular with a view to producing bioethenol, wherein the material is first admixed with water and is then passed to a reactor, in which the soaked material is subjected to a high temperature and a high pressure to such an extent that is it accessible for a subsequent treatment with enzymes, following which the treated material is separated into liquid part and a solid part, where the solid component is subsequently used for the production of bioethenol and enzymation and fermentation. Exclusively steam is used in the method and the corresponding system for heating, stirring and transport, as e.g. the transport through the various elements of the system is provided by a pressure difference between the compartments of the elements. The material (32) is discharged to an economizer (4), in which a separator (5) separates the material into a solid part and a liquid part.
Abstract: The present invention relates to method for oxidising an alkene comprising contacting said alkene with an AlkB-type oxidoreductase in the presence of oxygen, and a use of an AlkB-type oxidoreductase, preferably AlkB from Pseudomonas putida GPO1 or a variant thereof, for oxidising an alkene to an alcohol and/or acid.
Type:
Application
Filed:
January 18, 2013
Publication date:
January 8, 2015
Applicant:
Evonik Industries AG
Inventors:
Philip Engel, Thomas Haas, Jan Christoph Pfeffer, Oliver Thum, Christian Gehring
Abstract: The invention relates to fungal strains having at least one genetic modification which leads to a reduction of the activity of at least one fungal carboxylic acid transporter and to a method for producing or using said fungal strains.
Type:
Application
Filed:
December 12, 2012
Publication date:
January 8, 2015
Applicant:
THYSSENKRUPP INDUSTRIAL SOLUTIONS AG
Inventors:
Andreas Aurich, Martina Holz, Anne Kretzschmar, Christina Otto, Gerold Barth, Isabel Waengler, Roland Arno Müller
Abstract: The present invention relates to genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers on the host cell the ability to isomerize xylose to xylulose. These genetic modifications are aimed at improving the efficiency of xylose metabolism and include, e.g., reduction of nonspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source.
Type:
Application
Filed:
June 24, 2014
Publication date:
January 8, 2015
Inventors:
Aaron Adriaan WINKLER, Sipko Maarten KUYPER, Wilhelmus Theodorus Antonius Maria DE LAAT, Johannes Pieter VAN DIJKEN, Jacobus Thomas PRONK
Abstract: The present invention provides methods for degrading or converting a cellulosic material using an enzyme composition in the presence of a reducing agent. The present invention also provides methods for producing a fermentation product and methods of fermenting a cellulosic material using an enzyme composition in the presence of a reducing agent.
Abstract: An object of the present invention is to provide a soft biomass decomposition method, a production method for a target substance from soft biomass, and an enzyme or group of enzymes for decomposing soft biomass. Provided is a soft biomass decomposition method, including a step of bringing an enzyme selected from specific exocellulase, endocellulase, and processive endocellulase into contact with soft biomass such as bagasse and rice straw. Also provided is a production method for a target substance from soft biomass by incorporating the soft biomass decomposition method as a step. Further provided is an enzyme or group of enzymes for decomposing soft biomass selected from specific exocellulase, endocellulase, and processive endocellulase.
Type:
Application
Filed:
January 29, 2013
Publication date:
January 8, 2015
Applicant:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy materials, to produce a product or intermediate, e.g., energy, a food, a fuel, or a material.
Type:
Application
Filed:
September 24, 2014
Publication date:
January 8, 2015
Inventors:
Marshall Medoff, Thomas Craig Masterman
Abstract: The present invention relates to methods of degrading or converting biomass material enriched with hemicellulosic material into fermentable sugars.
Type:
Grant
Filed:
December 6, 2011
Date of Patent:
January 6, 2015
Assignee:
Novozymes A/S
Inventors:
Prashant Iyer, Harry Showmaker, Hui Xu, Kishore Rane
Abstract: The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Type:
Application
Filed:
November 21, 2012
Publication date:
January 1, 2015
Inventors:
Janine Lin, Doreen Bohan, Michelle Maranta, Leslie Beresford, Michael Lamsa, Bjarne Gram Hansen, Frank Winther Rasmussen, Matt Sweeney, Douglas J. Boyle, III
Abstract: A method for manufacturing carboxylic acid that includes the following steps is provided. First, subjecting an aqueous mixture, including carboxylic acid and at least 5 wt. % dissolved magnesium chloride, to a forward extraction step using a first organic liquid, including an organic solvent, the organic solvent being selected from the group of C5+ ketones, thereby obtaining an organic carboxylic acid solution and an aqueous waste liquid including magnesium chloride. Second, subjecting the organic carboxylic acid solution to a back extraction step wherein the carboxylic acid is extracted from the organic carboxylic acid solution into an aqueous liquid, thereby obtaining an aqueous carboxylic acid solution and a second organic liquid. Third, subjecting the aqueous waste liquid including magnesium chloride derived from the forward extraction to a thermal decomposition step at a temperature of at least 300° C., thereby decomposing the magnesium chloride to magnesium oxide and HCl.
Type:
Application
Filed:
December 21, 2012
Publication date:
January 1, 2015
Inventors:
André Banier De Haan, Jan Van Krieken, Tanja Dekic Zivkovic
Abstract: A microorganism expressing a vector encoding a CoA-dependent succinate semialdehyde dehydrogenase to efficiently produce a C4 compound, and methods for the use thereof.
Type:
Application
Filed:
June 30, 2014
Publication date:
January 1, 2015
Inventors:
Hong-soon RHEE, Young-min Lee, Jin-woo Kim, Eun-Young Park, Yeo-ju Song, Jin-hwan Park, Kwang-myung Cho