Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant, at least one catalyst, and certain aldehyde-suppressing additives. Foams so produced emit low levels of formaldehyde, acetaldehyde and propionaldehyde.

Abstract: This application relates to carboxylate dyes suitable for use in fabric care compositions and in the treatment of fabrics.

Abstract: A first aspect of the invention is a compound (sometimes also referred to herein as an “active agent” or “active compound”) of Formula Ia, or more particularly Formula Ib: or a pharmaceutically acceptable salt or prodrug thereof. Compositions thereof and methods of using the same (e.g. for the treatment of a neurological disease) are also described.

Abstract: Azo compounds are disclosed that do not form azoxy dimers and that do not have any reactive nitroso groups. Also disclosed are use of the azo compounds as mediators in optical and electrochemical diagnostic methods, as well as detection reagents, kits and test elements that include such azo compounds and that can be used in the diagnostic methods.

Abstract: A compound represented by formula (I). In the formula, R1 represents a hydrocarbon group of 1 to 10 carbon atoms; Z represents a hydrocarbon group of 1 to 10 carbon atoms or a cyano group; provided that R1 and Z may be mutually bonded to form a ring; X represents a divalent linking group having any one selected from —O—C(?O)—, —NH—C(?O)— and —NH—C(?NH)— on a terminal that comes into contact with Q; p represents an integer of 1 to 3; Q represents a hydrocarbon group having a valency of (p+1), provided that, when p is 1, Q may be a single bond; R2 represents a single bond, an alkylene group which may have a substituent or an arylene group which may have a substituent; q represents 0 or 1; r represents an integer of 0 to 8; and A+ represents a metal cation or an organic cation.

Abstract: A pigment preparation is provided, said preparation comprises an organic pigment comprising a chromophore Q1 and a derivative thereof comprising specific organic substituents via an aliphatic carbon atom in an amount of from 0.1 to 30 mol, based on 100 mol of the organic pigment as well as a process for its preparation and to its use in coloring an organic material such as plastics, coatings or inks.

Abstract: The present invention relates to nitrogenous associative molecules comprising at least one unit rendering them capable of associating with one another or with a filler by noncovalent bonds, and comprising a function capable of reacting with a polymer containing unsaturations so as to form a covalent bond with said polymer.

Abstract: Fluorescent phenyl xanthene dyes are described that comprise any fluorescein, rhodamine or rhodol comprising a particular C9 phenyl ring. One or both of the ortho groups on the lower C9 phenyl ring is ortho substituted with a group selected from alkyl, heteroalkyl, alkoxy, halo, haloalkyl, amino, mercapto, alkylthio, cyano, isocyano, cyanato, mercaptocyanato, nitroso, nitro, azido, sulfeno, sulfinyl, and sulfino. In one embodiment, halo and/or hydroxy groups are used. Optimal dyes contain a lower C9 phenyl ring in which both ortho groups are the same and the lower ring exhibits some form a symmetry relative to an imaginary axis running from the phenyl rings point of attachment to the remainder of the xanthene dye through a point para to the point of attachment. The phenyl xanthene dyes may be activated. Furthermore, the phenyl xanthene dyes may be conjugated to one or more substances including other dyes.

Abstract: An activity based probe (ABP) comprising a glycosidase inhibitor, and a detection-group. The ABPs of the inventions are used for diagnosing storage disorder for screening of compounds suitable for preventing and/or treating a storage disorder, for monitoring of therapeutic enzymes for lysosomal storage disorders, and for ultra-sensitive visualization of glycosidase-fusion proteins in molecular imaging.

Abstract: A sterically bulky stabilizer that is associated non-covalently with a benzimidazolone pigment. The sterically bulky stabilizer compound includes an aromatic acid derivative, and the presence of the sterically bulky stabilizer limits an extent of particle growth and aggregation, to afford nanoscale pigment particles.

Abstract: Provided is a pigment particle suitable for an ink capable of recording an image that is excellent in color developability and lightfastness, and has a yellow hue. The pigment particle is a pigment particle having a structure represented by the following formula (1), in which a maximum absorption wavelength of an absorption spectrum in a wavelength region of 200 nm or more and 800 nm or less is present in a range of 340 nm or more and 360 nm or less.

Abstract: A sterically bulky stabilizer that is associated non-covalently with a benzimidazolone pigment. The sterically bulky stabilizer compound includes an aromatic acid derivative, and the presence of the sterically bulky stabilizer limits an extent of particle growth and aggregation, to afford nanoscale pigment particles.

Abstract: This invention relates to a dispersant for an organic pigment comprising a compound represented by the below-described formula (1) or (2), and also to its use. According to the present invention, it is possible to provide a dispersant or the like, which can afford a coating formulation for a color filter. The coating formulation is prevented from an increase in viscosity and a reduction in storage stability even when the concentration of a pigment is high, and can fabricate the color filter with excellent transparency and color quality.

Abstract: The invention relates to a dye of the general formula (I) where D is the residue of a diazo component; R1 is hydrogen, (C1-C6-alkyl, (C1-C4)-alkoxy, hydroxyl, halogen, —NHCHO, —NHCO(C1-C6)-alkyl, —NHCOaryl, —NHSO2(C1-C6)-alkyl or —NHSO2aryl; R2 is hydrogen, (C1-C6)-alkyl, (C1-C4)-alkoxy, phenoxy or halogen; R3 is hydrogen, (C1-C6)-alkyl, substituted (C1-C6)-alkyl, (C3-C4)-alkenyl or substituted (C3-C4)-alkenyl; or R2 and R3 combine to form the radical —C*H(CH3)CH2C(CH3)2—, where the carbon atom marked * is attached to the phenyl nucleus; R4 is hydrogen, (C1-C6)-alkyl or phenyl; R5 is vinyl or a group of the formula —CHR6COR7, where R6 is hydrogen, (C1-C6)-alkyl or phenyl; R7 is (C1-C6)-alkyl, substituted (C1-C6)-alkyl, phenyl or substituted phenyl; and X is C1-C5)-alkylene. The invention for relates to a process to prepare the dye and their use.

Abstract: An azolylmethylidenehydrazine derivative represented by the formula (I) wherein Ar is an aryl group optionally having substituent(s) or a heteroaryl group optionally having substituent(s), R1 and R2 are the same or different and each is an alkyl group, a cycloalkyl group, an aralkyl group optionally having substituent(s), an aryl group optionally having substituent(s), a heteroarylalkyl group optionally having substituent(s), or R1 and R2 are bonded to each other to form a nitrogen-containing heterocyclic group optionally having substituent(s), and X is CH or a nitrogen atom, or a pharmacologically acceptable salt thereof is useful as a medicament, particularly as an antifungal agent, or an anti-inflammatory agent or an antiallergic agent.

Abstract: The present invention relates to a compound for photoresist, selected from the group consisting of a compound comprising an oxonol dye skeleton, a cyanine dye, a styryl dye, a compound comprising a merocyanine dye skeleton, a compound comprising a phthalocyanine dye skeleton, an azo compound, and a complex compound of an azo compound and a metal ion. The present invention further provides a photoresist liquid comprising at least one of the compound for photoresist and a method of etching a surface being processed using the photoresist liquid.

Abstract: This invention relates to an amino acid based on a naturally occurring non-polar, non-aromatic ?-amino acid, wherein said amino acid differs from the naturally occurring counterpart in that the side chain contains a diazirine ring. Furthermore provided are methods of synthesizing a (poly)peptide with one or more amino acids of the invention incorporated, methods for cross-linking interacting molecules, methods of synthesizing the amino acids of the invention, and a kit comprising the amino acids of the invention.

Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.

Abstract: Transglutaminase inhibitors and methods of use thereof are provided.

Abstract: The present invention provides a reactive dyestuff with an alkylthio group and a ?-sulfatoethylsulfone group, which is represented by formula (I), wherein D, R, R1, R2, R3, R4, Q, x, and y are defined the same as the specification. The reactive dyestuffs of the present invention not only have characteristics of high solubility, high alkali solubility, and easily being washed off for dyeing cellulose fiber, but also are suitably applied in cold-pad-batch dyeing, continuous-dyeing, printing, and digital printing.

Abstract: Described herein are ligand-functionalized/azo compounds and methods of use thereof.

Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.

Abstract: A process for coloration of a substrate comprising applying thereto means of an ink jet printer a composition comprising a medium and a compound of Formula (1): wherein: A is optionally substituted aryl; B is optionally substituted arylene; and R1 and R2 are each independently H or optionally substituted alkyl. Also claimed are novel compounds, compositions and ink-jet cartridges for use an ink-jet printer and substrate printed with an ink-jet printer.

Abstract: A lightfast colorant and a lightfast ink composition including the lightfast colorant utilize a lightfast colorant that is derived by covalently binding a cinnamate derivative and a conventional colorant. The lightfast colorant improves storage stability as well as lightfastness when added to an ink composition.

Abstract: The present invention relates to a silver halide color photographic light-sensitive material wherein at least one of light-sensitive silver halide emulsion layers includes a silver halide emulsion having a silver chloride content of at least 95 mol % and a silver iodide content of 0.05 mol % to 0.75 mol % and/or a silver bromide content of 0.05 mol % to 4.

Abstract: A process for coloration of a substrate comprising applying thereto by means of an ink jet printer a composition comprising a medium and a compound of Formula (1): 1

Abstract: The present invention relates to photolabile protective groups for synthesizing biopolymers, in particular nucleic acids.

Abstract: Mono- and Bis-Azo/Hydrazone Pyrrole Pigments and Methods for preparing same.

Abstract: The invention relates to oxazine derivatives by means of which a broad spectrum of material to be examined can be marked and identified using fluorescence techniques.

Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.

Abstract: Novel addition products of hydroxyl-protecting groups (such as isocyanates) with oxyalkylene-substituted intermediates, such as poly(oxyalkylenated) aniline compounds, for the eventual production of substituted, and substantially pure, colorants, particularly diazo and triphenylmethane derivatives, through the reaction of such intermediates with certain reactants are provided. These new colorants exhibit improved wax and/or oil solubility and high purity, particularly due to the inability of certain impurities to deleteriously react with the protected hydroxyl groups of either the intermediate or the colorant during and/or after formation thereof. A method for producing such novel colorants through utilization of these novel substantially pure colorant intermediates is also provided.

Abstract: Compounds of the formula 1

Abstract: The present invention relates to the sodium salt of (Z)-2-hydroxy-5-[[4-[3-[4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]-1-piperidinyl]-3-oxo-1-phenyl-1-propenyl]phenyl]azo]benzoic acid, as well as to the pharmaceutical compositions containing it, to a procedure for its preparation and to its use. for the manufacture of medicaments for the treatment or prevention of inflammatory bowel disease.

Abstract: A compound of the formula I: wherein R is H or —N═N-2-carboxyphenyl; A is (CH2)n or —CH═CH—, wherein n is an integer from 0 to 10, or A may also be —CH(COOH)— when R is —N═N-2-carboxyphenyl; and X is a radical selected from the group consisting of: (i) Cl; (ii) COOR1, wherein R1 is p-nitrophenyl or N-succinimidyl; (iii) CONH—NHR2, wherein R2 is H, COO(t-butyl) or COObenzyl; (iv) CONH—[B]—NHR3, wherein R3 is H, COOR1, or CO—[B′]—maleimido, wherein R1 is t-butyl, p-nitrophenyl or N-succinimidyl, and B and B′, the same or different, are (CH2)n wherein n is an integer from 2 to 10; (v) CONH—[B]—COOR4, wherein R4 is H, C1-C8 alkyl, N-succinimidyl; (vi) CONH—[B]—OH; (vii) CONH—[B]—CONH—NHR2, wherein R2 is H, COO(t-butyl) or COObenzyl; and (viii) NHR2, wherein R2 is H, COO(t-butyl) or COObenzyl, when A is —CH(C

Abstract: Described is a heterocycle-containing carboxylic acid derivative represented by the following formula (I): 1

Abstract: A dye which is represented by any of the following general formula (1), (2), (3) or (4), an ink for inkjet recording which contains at least one of the dyes, and an ink jet recording method which uses the ink. The dye has heterocyclic group which may be substituted and has at least one ionic aqueous group in a molecule.

Abstract: This invention is directed to sulfonyl aromatic hydroxamic acid compounds and salts thereof that, inter alia, inhibit matrix metalloprotease (MMP) activity and/or aggrecanase activity.

Abstract: In accordance with the present invention, there is provided a novel class of heterocyclic compounds. Compounds of the invention contain a substituted, unsaturated five, six or seven membered heterocyclic ring that includes at least one nitrogen atom and at least one carbon atom. The ring additionally includes three, four or five atoms independently selected from carbon, nitrogen, sulfur and oxygen atoms. The heterocyclic ring has at least one substituent located at a ring position adjacent to a ring nitrogen atom. This mandatory substituent of the ring includes a moiety (B), linked to the heterocyclic ring via a carbon-carbon double bond, a carbon-carbon triple bond or an azo group. The mandatory substituent is positioned adjacent to the ring nitrogen atom. Invention compounds are capable of a wide variety of uses. For example heterocyclic compounds can act to modulate physiological processes by functioning as agonists and antagonists of receptors in the nervous system.

Abstract: Compounds having Formulas 5 and 6 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids.

Abstract: Aryl-substituted and aryl and (3-oxo-1-propenly)-substituted benzopyran, benzothiopyran, 1,2-dihydroquinoline, and 5,6-dihydronaphthalene derivatives have retinoid negative hormone and/or antagonist-like biological activities. The invented RAR antagonists can be administered to mammals, including humans, for the purpose of preventing or diminishing action of RAR agonists on the bound receptor sites. Specifically, the RAR agonists are administered or coadministered with retinoid drugs to prevent or ameliorate toxicity or side effects caused by retinoids or vitamin A or vitamin A precursors. The retinoid negative hormones can be used to potentiate the activities of other retinoids and nuclear receptor agonists. For example, the retinoid negative hormone called AGN 193109 effectively increased the effectiveness of other retinoids and steroid hormones in in vitro transactivation assays. Additionally, transactivation assays can be used to identify compounds having negative hormone activity.

Abstract: Disclosed are an azo dye having the following formula (1), an ink-jet ink comprising the aforesaid azo dye, an ink-jet recording method using the aforesaid ink-jet ink, and a thermal transfer recording material comprising the aforesaid azo dye: wherein Z represents an atomic group which forms, together with a nitrogen atom, a five-, six- or seven-membered ring, R1 represents a hydrogen atom, an oxy radical, an aliphatic group, an aliphatic oxy group, an acyl group, an aliphatic oxycarbonyl group, an aryloxycarbonyl group or an acyloxy group, R2, R3, R4 and R5, which may be the same or different, each represents an alkyl group, or R2 and R3 and/or R4 and R5 may be combined with each other to form a ring, and Dye represents a dye moiety group necessary for forming an azo dye.

Abstract: Described is a heterocycle-containing carboxylic acid derivative represented by the following formula (I): 1

Abstract: A compound shown by the general formula [1]: (Wherein, R1 and R2 are each independently a hydrogen atom, a lower alkyl group or a cyano group, and is an optionally substituted heterocyclic compound.); or a salt thereof.

Abstract: The present invention provides novel compounds of Formula I: 1

Abstract: The present invention provides a novel heterylaniline azo dye as well as an ink-jet recording ink and an ink-jet recording method enabling the formation of an image having a good hue and high durability to light and ozone gas. The ink-jet recording ink contains a heterylaniline azo dye derivative having a novel structure. The ink-jet recording method is characterized in that an image is formed by using the ink described above on an image-receiving material comprising a support having thereon an ink-receiving layer containing white inorganic pigment particles.

Abstract: Azo compounds of the formula (I) are functionalized with heterocycles.

Abstract: A polymerization initiator composition, comprising an azobisamidine salt represented by the general formula (1) ##STR1## wherein R.sup.1 and R.sup.2 independently represent an alkyl group or a cycloalkyl group, providing that R.sup.1 and R.sup.2 may together form an aliphatic ring, and Y represents --C(.dbd.NR.sup.3)--NH--R.sup.4 or a guanyl group represented by the formula (2) ##STR2## wherein R.sup.3 and R.sup.4 independently represent a hydrogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, an allyl group, a phenyl group, or a substituted phenyl group, R.sup.5 represents a lower alkylene group optionally containing a substituent group, and R.sup.6 represents a hydrogen atom or a hydroxyalkyl group, and X represents a chlorine atom, a bromine atom, or a CH.sub.3 COO-- group, and a hydrophilic organic compound.

Abstract: Polymerizable azo dyes I ##STR1## in which R.sup.1 is an aryl group,R.sup.2 is cyano, C.sub.1 -C.sub.4 -alkoxycarbonyl or nitro,R.sup.3 and R.sup.4 are hydrogen, C.sub.1 -C.sub.12 -alkyl or C.sub.1 -C.sub.6 -alkoxy,R.sup.5 is hydrogen, C.sub.1 -C.sub.12 -alkyl, C.sub.5 -C.sub.7 -cycloalkyl or C.sub.3 -C.sub.4 -alkenyl,R.sup.6 is hydrogen or methyl,Y is C.sub.2 -C.sub.10 -alkylene which can be interrupted by 1 to 3 nonadjacent oxygen atoms or imino or C.sub.1 -C.sub.4 -alkylimino groups, andW is oxygen, imino or C.sub.1 -C.sub.4 -alkyliminoare used to prepare copolymers which show nonlinear-optical properties.

Abstract: Diaza-18-crown-6 compounds of the formula I: ##STR1## wherein X is a phenol, naphthol or quinolinol moiety selected from those of the formulae: ##STR2## R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are independently selected from hydrogen, halo, cyano, nitro, (C.sub.1 -C.sub.6) alkyl, (C.sub.2 -C.sub.8) acyl, acetamido, mercapto, alkyl or arylsulfonyl, trifluoromethyl, aryl, and substituted aryl wherein the aryl moiety is selected from phenyl and naphthyl and the aryl substituent is selected from halo, cyano, nitro, (C.sub.1 -C.sub.6) alkyl, (C.sub.2 -C.sub.8) acyl, phenyl, acetamido, mercapto, alkyl or arylsulfonyl and trifluoromethyl; provided that when R.sub.1, R.sub.2, R.sub.3 and R.sub.5 are hydrogen and X is phenol, R.sub.4 is not nitro; and provided that when X is phenol and R.sub.5 is hydrogen, R.sub.1 (or R.sub.2) and R.sub.4 are not both nitro.

Abstract: There are described heat-developable photosensitive image-recording materials which include a compound having at least one cyclic 1,3-sulfur-oxygen moiety. The compound is stable in the photographic processing composition but capable of undergoing cleavage in the presence of an imagewise distribution of silver ions and/or soluble silver complex made available as a function of development to liberate a reagent in an imagewise distribution corresponding to that of the silver ion and/or the soluble silver complex. The reagent includes a photographically useful group such as a complete dye or dye intermediate.