Bicyclo Ring System Having The Hetero Ring As One Of The Cyclos Patents (Class 549/546)
  • Patent number: 4369328
    Abstract: New oxygenated alicyclic compounds of formula ##STR1## (X=OH, alkyl, O-alkyl) are useful as starting materials for the preparation of cyclohexadienic derivatives of formula ##STR2## (X=OH, alkyl, O-alkyl). They are converted into compounds (III) by treating them with an acidic dehydrating agent in the presence of an inert organic solvent.Compounds (I) are manufactured by reacting compounds (II) ##STR3## (X=OH, alkyl, O-alkyl) with an organic peracid.
    Type: Grant
    Filed: July 24, 1981
    Date of Patent: January 18, 1983
    Assignee: Firmenich SA
    Inventors: Karl-Heinrich Schulte-Elte, Bernard Egger, Bernard Muller
  • Patent number: 4353922
    Abstract: Compounds of the formula ##STR1## wherein the serrated lines denote both endo and exo forms; R.sub.1 and R.sub.2 are the same or different and are C.sub.1 to C.sub.6 alkyl, C.sub.5 or C.sub.6 cycloalkyl, C.sub.5 or C.sub.6 cycloalkenyl, phenyl optionally substituted with C.sub.1 to C.sub.6 alkyl, C.sub.1 to C.sub.6 alkoxy or halo, or 5 or 6 membered heterocyclic aryl wherein the heteroatom is oxygen, nitrogen or sulfur; R.sub.3 is a C.sub.1 to C.sub.6 alkyl radical; R.sub.4 and X are optionally present, and when present R.sub.4 is a C.sub.1 to C.sub.6 alkyl radical or hydrogen and X is an inorganic or organic anion which forms a pharmaceutically acceptable salt. Methods for preparing these compounds are also disclosed. The compounds of the present invention are useful as anticholinergic agents.
    Type: Grant
    Filed: March 13, 1981
    Date of Patent: October 12, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Jurg R. Pfister
  • Patent number: 4352937
    Abstract: Novel cyclohexane derivatives of the formula: ##STR1## wherein R.sup.1 represents an alkyl group, R.sup.2 and R .sup.3 each represents a hydrogen atom or an alkyl group, and X represents an epoxy or hydroxy group; are useful as aroma chemicals.
    Type: Grant
    Filed: August 14, 1978
    Date of Patent: October 5, 1982
    Assignee: Shell Oil Company
    Inventors: Robin T. Gray, Aaldert J. De Jong
  • Patent number: 4329508
    Abstract: A process for making mixed 2- and 3-C.sub.1 -C.sub.10 alkyl-2-cyclopenten-1-ones from a corresponding alkylcyclopentadiene by epoxidation to the oxiranes, hydrolysis to the diols, dehydration of the diols and rearrangement of the resulting mixed alkylcyclopentenones. The resulting product can be used to make methylcyclopentenolone, a synthetic maple flavor.
    Type: Grant
    Filed: September 29, 1980
    Date of Patent: May 11, 1982
    Assignee: SCM Corporation
    Inventors: T. L. Ho, Shing-Hou Liu