Abstract: Novel 4,4-diarylbutadiene-substituted diorganopolysiloxanes having the structural formulae (1) or (2): in which A is a radical of formula (3) below: are useful sunscreens for UV-photoprotecting human skin against the damaging effects of UV-radiation, notably UV-A radiation.

Abstract: The present invention relates to (meth)acrylamide monomers of the formula: wherein R is H or CH3, R1 is selected from H, substituted and unsubstituted alkyl groups having 1 to 8 carbon atoms, substituted and unsubstituted benzene and toluene groups and and R2, R3 and R4 are independently selected from alkyl groups having 1 to 8 carbon atoms, substituted and unsubstituted benzene and toluene groups, and —OSiR5R6R7 wherein R5, R6 and R7 are independently selected from the group consisting of straight or branched alkyl groups having 1 to 4 carbon atoms. Polymers made therefrom are also disclosed.

Abstract: This invention provides compounds of Formula I, N-oxides and suitable salts thereof wherein A is O or S(O)?m#191;J is a phenyl or heterocyclic ring as defined herein; and R1 through R12, n, m and r are as defined in the disclosure. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula I, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula I, an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent.

Abstract: Including a triazine UV light absorber having a silane group in a coating improves scratch and mar resistance after weathering.

Abstract: The invention concerns organosilicon compounds, their method of preparation and their use as coupling agents for deposition, at the surface of a solid support, an organized self-assembled monolayer. The invention also concerns a method for obtaining solid supports whereof the surface is modified by an organized self-assembled monolayer comprising a system of said organosilicon compounds, and the use of said solid supports for biomolecular synthesis or immobilization.

Abstract: In the synthesis of an amide compound through reaction of an acyl fluoride group-bearing compound with an amino compound, a reaction mixture contains the amide compound and hydrogen fluoride or a hydrofluoric acid amine salt. The amide compound is recovered in high purity form by adding an oxide, carbonate or hydroxide of an alkaline earth metal to the reaction mixture to convert the hydrogen fluoride or hydrofluoric acid amine salt to an alkaline earth metal fluoride salt that can be readily removed by filtration.

Abstract: Compounds of formula (I, II, or III), wherein X is OH; Y is OH, H, lower alkyl of one to six carbons or heteroatoms or F; Z and Z? are independently H, lower alkyl or Q3Si where Q is lower alkyl or aryl; n is 3–50; n? is 2–50; A and B are independently a) alkyl of one to ten carbons or heteroatoms, b) aryl of four to ten carbons or heteroatoms, c) cyclic of three to ten carbons or heteroatoms, or moieties of the formulas (d, e, or f); R1–R11 groups are each independently hydrogen, alkyl of one to ten carbons or heteroatoms, aryl of 4 to 14 carbons or heteroatoms, arylalkyl of five to twenty carbons or heteroatoms; unsubstituted carbonyl or substituted carbonyl. Heteroatoms are nitrogen, oxygen, silicon or sulfur. At least one of A or B, or both A and B are d), e), or f). The compounds of formula (I) inhibit protease enzymes and can be used as pharmaceuticals.

Abstract: A composition including nanoparticles each having an acidic polymerizable siloxane moiety. For example, a hydrolysis stable, self-etching, self-priming dental adhesive composition including 90 to 10 percent by weight of an aqueous phase, and 10 to 90 percent by weight of acidic polymerizable nanoparticles. The acidic polymerizable nanoparticles are obtainable by hydrolysis of a mixture containing one or more hydrolyzable organosilicon compounds wherein (i) at least a portion of the hydrolyzable organosilicon compounds contains one or more polymerizable groups and (ii) at least a portion of the hydrolyzable organosilicon compounds contain one or more acidic moieties.

Abstract: Compounds of formula (I, II or III), wherein X is OH; Y is OH, H, lower alkyl of one to six carbons or heteroatoms or F; Z and Z? are independently H, lower alkyl or Q3Si where Q is lower alkyl or aryl; n is 3-50; n? is 2-50; A and B are independently a) alkyl of one to ten carbons or heteroatoms, b) aryl of four to seven carbons or heteroatoms, c) cyclic of three to ten carbons or heteroatoms, or moieties of the formulas (d, e, or f); R1-R11 groups are each independently hydrogen, alkyl of one to ten carbons or heteroatoms, aryl of 4 to 14 carbons or heteroatoms, arylalkyl of five to twenty carbons or heteroatoms; unsubstituted carbonyl or substituted carbonyl. Heteroatoms are nitrogen, oxygen, silicon or sulfur. At least one of A or B, or both A and B are d), e), or f). The compounds of formula (I) inhibit protease enzymes and can be used as pharmaceuticals.

Abstract: The invention relates to amido-functional aminopolydiorganosiloxanes, a method for the preparation thereof, formulations containing such amido-functional aminopolydiorganosiloxanes, and the use thereof.

Abstract: Novel fluorinated amide compounds having siloxane bonds or silalkylene bonds, when crosslinked with organic peroxides, yield fluoro-rubber having excellent chemical resistance and solvent resistance.

Abstract: The invention relates to novel phthalamides of the formula (I) in which disclosure. The invention further relates to a process for preparing these compounds and their use for controlling pests.

Abstract: The invention relates to hydrolyzable and polymerizable silanes of formula (I), methods of preparing the same, and their use in the production of silica polycondensates, silica heteropolycondensates, polymers, heteropolymers, and other products. B=straight-chain or branched substituted or unsubstituted organic radical having 2 to 50 carbon atoms comprising one or more acrylate and/or methacrylate groups, the —CO—NH— group in the formula I being bonded to a carbon atom of the radical B, and B containing no norbornene, bicyclo[2.2.2]oct-2-ene or 7-oxabicyclo[2.2.

Abstract: Disclosed is a polyether polyurethane comprising (A) at least one polyisocyanate having two or more isocyanate groups, which is selected from the group consisting of an aromatic polyisocyanate and an aliphatic polyisocyanate; (B) a polyoxytetramethylene glycol (PTMG) having a number average molecular weight of from 500 to 4,000, a molecular weight distribution (Mw/Mn) of 1.75 or less, and a content of high molecular weight PTMG molecules of 10% by weight or less; and (C) at least one chain extender selected from the group consisting of a C2-C10 polyol having two or more hydroxyl groups and a C2-C10 polyamine having two or more amino groups. Also disclosed is a urethane prepolymer which comprises the above-mentioned components (A) and (B) and which has terminal isocyanate groups.

Abstract: The present invention relates to oxygenated esters of 4-substituted-phenylamino benzhydroxamic acid derivatives, pharmaceutical compositions, and methods of use thereof.

Abstract: The composition formed by mixing an organosilane with an organic carbonate. Water-stabilized organosilane compounds. A water stable composition made from the organic carbonate and organosilane composition and water. A method of treating a substrate by mixing or contacting the substrate with the product, compound, or composition of this invention for a period of time sufficient for treatment of the substrate. A treated substrate having adhered thereto the product, compound, or composition of this invention. A method of dyeing and treating a substrate. A method of antimicrobially treating a food article. A method of antimicrobially coating a fluid container. A method of antimicrobially coating a latex medical article.

Abstract: Novel phthalamides of the formula (I) 1

Abstract: The invention relates to the synthesis of bis trialkylsilylamide. The synthesis includes subjecting the amide to the action of a trialkylsilyl halide on an amide bearing a Rf group in the presence of a base whose halide, or halohydrate, is insoluble in the presence of a covalent and non-hydrophilic solvent. The invention is applicable to organic synthesis.

Abstract: A water repellent composition comprising a compound of the following formula 1, and a compound of the following formula 4 and/or a compound of the following formula 5: RfSi(R)p(X)3−p  Formula 1 RFSi(R1)q(X1)3−q  Formula 4 SiX24  Formula 5 wherein Rf is a fluorine-containing organic group having an etheric oxygen atom, RF is a fluorine-containing organic group having no etheric oxygen atom, each of R and R1 which are independent of each other, is a C1-6 hydrocarbon group containing no fluorine atom, each of X, X1 and X2 which are independent of one another, is a halogen atom or a hydrolyzable group, and each of p and q which are independent of each other, is 0, 1 or 2.

Abstract: The invention relates to a process for the preparation of compounds of the formula or, if appropriate, a tautomer thereof, in each case in the free form or in salt form, in which A, X, Y, Z, R2, R3, R4, R5, R7, R9 and n are as defined in claim 1 and the C═N double bond marked with E has the E configuration, which comprises a1) reacting either a compound of the formula (II) mentioned above with a compound of the formula (III) mentioned above, in which X1 is a leaving group, or a2) a compound of the formula (IV) mentioned above, if appropriate in the presence of a base, with a compound of the formula (V) mentioned above, or b1) reacting a compound of the formula (VI) mentioned above with a compound of the formula R7—A—X2 (VII), in which X2 is a leaving group, and either further reacting the compound thus obtainable, of the formula (IV), for example according to method a2), or b2) reacting it with hydroxylamine or a salt thereof, if appropriate in the presence of a basic or

Abstract: Compounds of the formula where the variables have the meaning defined in the specification, which bind specifically or selectively to to RAR&agr; retinoid receptors.

Abstract: The invention concerns organosilicon compounds, their method of preparation and their use as coupling agents for depositing, at the surface of a solid support, an organised self-assembled monolayer. The invention also concerns a method for obtaining solid supports whereof the surface is modified by an organised self-assembled monolayer comprising a system of said organosilicon compounds, and the use of said solid supports for biomolecular synthesis or immobilisation.

Abstract: Disclosed are compounds that inhibit the microbial NAD synthetase enzyme. For example, disclosed are compounds of the formula Ar1—X—Ar2—Y—L—Z—Q, wherein Q is Q1Ar3 or Ar3Q1; Ar1, Ar2, and Ar3 are independently aryl or heteroaryl, optionally substituted with one or more substituents; X, Y, and Z are independently selected from the group consisting of a covalent bond or groups containing one or more of C, H, N, O, S atoms; L is a linker and Q1 is an alkylenyl, alkylenyl carbonyloxy alkyl, or alkylenyl carbonylamino alkyl group, optionally having a substituent; a covalent bond; a group containing amidine or guanidine function wherein the amidine or guanidine may be optionally N-substituted with an alkyl; or a zwitterion; or a pharmaceutically acceptable salt thereof.

Abstract: A charge transport composition containing aromatic amines with crosslinkable silanes as represented by the formula 1

Abstract: Novel fluorinated amide compounds having siloxane bonds or silalkylene bonds, when crosslinked with organic peroxides, yield fluoro-rubber having excellent chemical resistance and solvent resistance.

Abstract: A novel perfluoropolyether-modified aminosilane cures into a film having improved water and oil repellency and anti-staining properties. A surface treating agent comprising the aminosilane, and an article with a coating of the aminosilane are also provided.

Abstract: Disclosed herein is a process for the manufacture of a blocked mercaptosilane wherein the process is selected from the group consisting of: (1) reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product; (2) reacting an alkali salt of a mercaptosilane with the appropriate acid anhydride or acid halide; (3) transesterifying a mercaptosilane and an ester in the presence of an alkali metal of an acid corresponding to the ester; (4) transesterifying a thioester silane and another ester; (5) transesterifying a 1-sila-2-thiacyclopentane or a 1-sila-2-thiacyclohexane and an ester; and (6) reacting an alkali metal salt of a thioacid with a haloalkylsilane.

Abstract: Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include chiral C1-C6 TunaPhos ligands. The ruthenium TunaPhos complex reduces ketones to the corresponding alcohols with 95-99.6% enantioselectivity. The transition metal complexes of the chiral ligands are useful in asymmetric reactions such as asymmetric hydrogenation, hydride transfer, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, hydrocarboxylation, isomerization, allylic alkylation, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition and epoxidation reactions.

Abstract: A method of controlling Take-all disease of plants, by applying, preferably to the seeds prior to planting, a fungicide of the formula wherein Z1, and Z2 are C and are part of an aromatic ring which is benzene.

Abstract: The present invention discloses hydrogen bond stabilized surface modifying agents having a fluorinated or semi-fluorinated carbon-containing tail group, an internal moiety capable of intermolecular hydrogen bonding or related acid-base interactions and a head group capable of reacting or interacting with surfaces such as metal, non-metallic, ceramic, other inorganic oxide or organic surfaces. The present invention also discloses cost effective method for making the agents, methods for treating surfaces therewith, the treated surfaces and devices made therefrom.

Abstract: The present invention relates to a series of novel silicone alkoxylated esters which have terminal carboxyl groups that form salt complexes with certain amid containing cationic compounds to form very mild conditioning products suited for personal care applications like shampoos, body wash, hand wash and bath products.

Abstract: Silanes of the general formula are prepared, wherein R1, R2 and R3 in the molecule are the same or different and represent aliphatic or aromatic hydrocarbon groups, R4 is a divalent hydrocarbon group with 4 to 12 carbon atoms and a lateral hydroxyl group, wherein the hydrocarbon group can be interrupted by an ether oxygen, R5 is a hydrophilic, ionic group. A method for synthesizing these compounds is described. The silanes greatly lower the surface tension of aqueous solutions, the surface tension being reduced to values of about 23 mN/m. The silanes are biologically degradable and have pronounced surfactant properties.

Abstract: There are disclosed novel quaternary ammonium functional silicones and silanes and methods to make quaternary ammonium functional silicones and silanes. Quaternary ammonium functionality may be provided through the use of cationizing agents.

Abstract: A method for the preparation of hydroxythiol compounds by reacting a hydroxyl-protected halide compound having the structure: X—R—OPg with magnesium in a Grignard-suitable solvent to form a hydroxyl-protected magnesium halide compound, wherein R is selected from substituted or unsubstituted aliphatic radicals, substituted or unsubstituted cyclic aliphatic radicals, substituted or unsubstituted aromatic radicals, substituted or unsubstituted araliphatic radicals and substituted or unsubstituted heterocyclic radicals; Pg is a protecting group; and X is selected from the group consisting of F, Cl, Br and I; then reacting said hydroxyl-protected magnesium halide compound with sulfur in the Grignard-suitable solvent to form a hydroxyl-protected thiomagnesium halide compound; and hydrolyzing the protected hydroxyl group to form a hydroxythiomagnesium halide compound and converting the thiomagnesium halide to a thiol; wherein the protecting group is selected so that species formed by the de-protection

Abstract: Silicone-containing organic compounds useful as modulators of mammalian nuclear hormone receptors, particularly the retinoid receptors and the farnesoid receptors.

Abstract: Secondary amine-functional silanes comprising at least one ester group and at least one amide group are disclosed. The secondary amine-functional silanes are preparable from relatively inexpensive, commercially available raw ingredients, are stable at room temperature and are reactive toward electrophiles. Also disclosed are silane-terminated polymers, silane-terminated polyurethane dispersions, and moisture-cured polymers derived therefrom.

Abstract: An adhesion promoter containing silane, and carbamate, thiocarbamate or urea functionality, and electron donor or electron acceptor functionality, displays low volatility.

Abstract: Ortho-substituted arylmetal compounds are prepared by deprotonation of aromatics which have a hydrogen atom in the ortho position relative to at least one halogen atom, one trifluoromethoxy group, one dialkylamino group, one nitrile group, one alkoxy group or one dialkylamido group. The arylmetal compounds can then be reacted with electrophilic reagents. Deprotonation of the aromatics is carried out using alkyl- or arylmetal compounds or metal hydrides in the presence of a catalytic amount of a secondary metal amide.

Abstract: The invention provides a process for producing an &agr;-hydroxy-carbonyl compound or an &agr;-protected hydroxy-carbonyl compound by reacting a carbonyl compound (I) with a compound (II) and a compound (III). The compounds (I), (II) and (III) are defined below. R1, R2, R3 and R4 are an organic group. PG is a protective group for hydroxy group. Y is R4N, S or O. The product is useful in pharmacology.

Abstract: The invention relates to polysiloxanes containing carboxyl groups that are useful for imparting water-repellency to substrates, a process for their preparation, a water-repellent system containing such polysiloxanes, and a process for the production of hydrophobic substrates.

Abstract: The present invention provides a system for the production of chemical compounds and libraries of compounds that are complex, stereochemically and regioselectively pure, and may mimic the structural or functional properties of a peptide. The invention provides methods for producing collections of peptidomimetic compounds which, in one preferred embodiment, comprises (1) providing two diversifiable monomers containing terminal reactive moieties; (2) reacting the monomers under conditions that allow for the control of stereochemistry as well as chemoselectivity; and (3) generating diversifiable isolable compounds or libraries of compounds.

Abstract: The invention concerns a complex containing biologically assimilable orthosilicic acid and a process of preparation of said complex. In this complex, orthosilicic acid is complexed with a polypeptide and the complex is under solid, stable and concentrated form. The present invention also concerns cosmetic or therapeutic compositions, and a nutritional supplement containing said complex.

Abstract: For preparing bis-silyl carboxamides in a semi-continuous, reacting an amide or the N-trimethylsilyl derivative thereof with a silylating agent and, at the same time, extracting the bis-silyl carboxamide formed by distillation under reduced pressure.

Abstract: The present invention relates to novel dimethicone copolyol amido quaternary compounds bearing a cationic group and an amido group. This invention also relates to a specific amido amine intermediate useful in the preparation of the compounds of the present invention. Compounds of the present invention are useful in the preparation of personal care products, specifically shampoos, conditioners and body washes.

Abstract: Coatings are provided with very low surface energies provided by fluorine and/or silicone moieties. Aqueous dispersions of externally chain extended polyurethane compositions terminated by hydrolyzable and/or hydrolyzed silyl groups and containing dispersing or emulsifying groups, particularly carboxyl groups are provided. Also polyurethane dispersions which are substantially organic solvent free which cure to water and solvent resistant, tough, scratch resistant, preferably light stable polyurethane films are provided. Such films are useful as anti-fouling marine coatings. The compound RfR′fCFCOOCH2C(R)(CH2OH)2 is provided.

Abstract: The present invention relates to polymerizable terminal group-containing polyorganosiloxane having a number average molecular weight of 500 to 100000 represented by the following Formula (1): wherein R1, R2, R3, R4 and R5 each represent a linear or branched alkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 4 to 10 carbon atoms or an aryl-containing group having 6 to 10 carbon atoms; R6 represents a hydrogen atom, a linear or branched alkyl group having 1 to 5 carbon atoms or an aryl-containing group having 6 to 10 carbon atoms; n represents 1 or more and m represents 0 or more, in which n+m represents an average polymerization degree and is 4 to 1100; X represents an alkylene group having 2 to 20 carbon atoms; Y represents —OCH2CH2—, —OCH(CH3)CH2— or —OCH2CH(CH3)—; p represents 3 or more; and Z represents an alkylene group having 1 to 20 carbon atoms.

Abstract: The invention relates to a novel amino acid silicon polymer with good adhesion to the keratin layer of the skin, a method of preparing the amino acid silicon polymer, a cosmetic particles surface-treated with the amino acid silicon polymer, and a color cosmetic composition including the cosmetic particles. According to the present invention, the particles surface-treated up to 3% to the maximum with the amino acid silicon polymer prepared by reacting an amino acid and a functional silicon polymer in the manner of organic synthesis have water resistance and usability peculiar to silicon-treated pigments and take positive surface charges, thereby offering good adhesion to the skin and durability. Due to these characteristics, the cosmetic containing the surface-treated particles of the present invention is superior in the cosmetic effect to that containing the conventional surface-treated particles.

Abstract: Intermediates having the formula wherein BI is —CH2OH or —CH2ORP, and RP is an alcohol protecting group; a is 1, 2, or 3; TI is —OH or QI is phenyl, naphthyl ohr heteroaryl having 1-3 substituents; Ra and Rc are the same, and are H, or are selected from alkyl, cycloalkyl and aryl groups, the groups being optionally substituted with one or more substituents selected from alkyl cycloalkyl, aryl, or —OH; or Ra and Rc together with the C—N—C chain to which they are bound, form a 5-7 membered ring; Rb and Rd are the same, and are H, or are selected from alkyl, cycloalkyl and aryl groups, the groups being optionally substituted with one or more substituents selected from alkyl, cycloalkyl, aryl, or —OH; and D is a directing group capable of directing lithiation alpha to a nitrogen atom of a nitrogen compound having D as a substituent bound to the nitrogen atom when the nitrogen compound is reacted with s-butyl lithium, are disclosed

Abstract: Hydrazine derivatives of the formula wherein R1 represents lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl or aryl-lower alkyl, R2 represents heterocyclyl or NR5R6, R3 represents hydrogen, lower alkyl, halo-lower alkyl, cyano-lower alkyl, hydroxy-lower alkyl, amino-lower alkyl, lower alkoxy-lower alkyl, lower alkoxycarbonyl-lower alkyl, lower cycloalkyl-lower alkyl, aryl-lower alkyl, heterocyclyl-lower alkyl, heterocyclylcarbonyl-lower alkyl, lower alkenyl, lower alkynyl, lower cycloalkyl, aryl, heteroaryl or aryl-lower alkyl, R4 represents lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl or a grouping of the formula -Z-aryl, -Z-heterocyclyl or —(CH2)n—, CH═CR7R8, R5 and R6 each independently represent hydrogen or lower alkyl, R7 and R8 each independently represent hydrogen or lower alkyl or R7 and R8 together represent lower alkylene in which one CH2 group is optionally replaced by a hetero atom, X and Z each repres

Abstract: An amine-, polyol-, amide-, dimethyl-functional siloxane copolymer and a method for its preparation are disclosed. The copolymer is suitable for use in fiber treatment compositions. The copolymer provides good hand, resistance to yellowing, and hydrophilicity to fibers treated therewith.