Boron Containing Patents (Class 568/1)
-
Publication number: 20090184289Abstract: A method for producing high-purity 2-cyanophenylboronic acid, characterized by reacting benzonitrile, lithium 2,2,6,6-tetramethylpiperidide, and trialkoxyborane, adding an aqueous acidic solution to a reaction solution containing the obtained 2-cyanophenylboronic acid, carrying out a contact treatment at a pH of below 7 in the presence of a water-immiscible organic solvent, and then obtaining the 2-cyanophenylboronic acid from the organic layer.Type: ApplicationFiled: April 11, 2007Publication date: July 23, 2009Inventor: Shinichiro Nakamura
-
Publication number: 20090134384Abstract: The present invention relates to the use of aromatic boronic acid or borinic acid derivatives in organic electronic devices, in particular electroluminescent devices.Type: ApplicationFiled: April 6, 2006Publication date: May 28, 2009Applicant: Merck Patent GmbHInventors: Philipp Stoessel, Esther Breuning, Arne Buesing, Amir Hossain Parham, Holger Heil, Horst Vestweber
-
Patent number: 7498468Abstract: 4-Aminopicolinic acids having tri- and tetra-substituted aryl substituents in the 6-position, and their amine and acid derivatives, are potent herbicides demonstrating a broad spectrum of weed control.Type: GrantFiled: October 4, 2007Date of Patent: March 3, 2009Assignee: Dow AgroSciences LLCInventors: Terry W. Balko, John F. Daeuble, Thomas L. Siddall
-
Publication number: 20090030220Abstract: The present invention provides a transparent desiccant with a high moisture absorption capacity which is suitable for use as a desiccant for organic EL devices (especially top-emitting organic EL devices). More particularly, the invention provides a transparent desiccant comprising an organometallic compound obtained by reacting a metal alkoxide with a polyol.Type: ApplicationFiled: July 28, 2005Publication date: January 29, 2009Inventors: Teruo Uchibori, Kaneto Ohyama, Yusuke Nakajima, Shouichi Aoki, Shinichi Miura, Yui Segawa
-
Publication number: 20080306302Abstract: A process for the preparation of organic cation tetrakis(Faryl) borate salts. The process includes preparation of intermediate, mono-hydrazine substituted (Faryl) compound, from (Faryl) compound using hydrazine at temperatures below 78° C. A stoichiometric excess of hydrazine to the (Faryl) compound to the (Faryl) compound is used. The process further includes the preparation of the organic cation tetrakis(Faryl) borate in ethereal medium.Type: ApplicationFiled: December 8, 2006Publication date: December 11, 2008Inventor: Bruce C. Berris
-
Publication number: 20080279746Abstract: A process for fluorination of borohydride salts including providing a reaction medium comprising HF and a superacid. A borohydride salt compound is added to the reaction medium. The borohydride salt is reacted with the with the reaction medium under conditions to form a fluorinated borohydride salt. In addition, reactor vessels may be provided for reacting the HF, superacid additive and borohydride that are fabricated from materials resistant to superacid compositions.Type: ApplicationFiled: July 9, 2008Publication date: November 13, 2008Applicant: AIR PRODUCTS AND CHEMICALS, INC.Inventors: Wade H. Bailey, III, William Jack Casteel, JR., Sergei Vladimirovich Ivanov, Xukun Luo
-
Publication number: 20080262257Abstract: A manufacturing method for one of, or a mixture of, an optically active allylboron compound and racemic or optically active boryl cyclopropane, including a coupling reaction, in the presence of a catalyst, between allyl compound and diboron compound. It is preferred that a copper (I) complex is used as the catalyst. It is preferred that a counterion of the copper (I) complex is an alkoxide or a hydride. It is preferred that the copper (I) complex has a phosphine ligand. It is preferred that the phosphine ligand is a chiral phosphine ligand.Type: ApplicationFiled: April 10, 2008Publication date: October 23, 2008Applicant: NIPPON CHEMICAL INDUSTRIAL CO., LTDInventors: Masaya SAWAMURA, Hajime ITO
-
Publication number: 20080251169Abstract: An ionic liquid is disclosed A precursor composition that comprises at least one ionic liquid and at least one energetic material is also disclosed, as is a method of synthesizing an ionic liquid and a method of desensitizing an explosive composition.Type: ApplicationFiled: April 13, 2007Publication date: October 16, 2008Applicant: ALLIANT TECHSYSTEMS INC.Inventors: Steven M. Nicolich, Alexander J. Paraskos, Daniel W. Doll, Gary K. Lund, Wendy A. Balas
-
Patent number: 7402703Abstract: There is herein provided a process for Zr-mediated hydroboration of alkynes which offers (E)-vinylboronic esters in high yield with stereoselectivity and regioselectivity.Type: GrantFiled: June 6, 2006Date of Patent: July 22, 2008Assignee: WyethInventor: Yanong Daniel Wang
-
Patent number: 7399645Abstract: The invention pertains to bioconjugation systems comprising sterically constrained cis-diols and borates.Type: GrantFiled: May 11, 2005Date of Patent: July 15, 2008Assignee: Applera CorporationInventors: Ricky F. Baggio, Alison L. Sparks, Rouh-Rong Juo, Jaime E. Arenas
-
Patent number: 7390670Abstract: Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula: is reacted with peroxide. Sig is a non-polymeric organic group, B is a boron atom, and each R is independently selected from hydrogen, alkyl and aryl groups and can be joined together as a straight or branched alkylene chain forming a ring or as an aromatic ring. A detectable product compound of the formula Sig—OH or Sig—O? is produced and detected by measuring color, absorbance, fluorescence, chemiluminescence, or bioluminescence. The signalling compound itself does not possess the detectable property or does so only to a very weak degree. The methods can be used as a detectable signal in assays for peroxide or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs.Type: GrantFiled: February 20, 2003Date of Patent: June 24, 2008Assignee: Lumigen, Inc.Inventors: Hashem Akhavan-Tafti, Robert A. Eickholt, Kenneth S. Lauwers, Richard S. Handley
-
Publication number: 20080138269Abstract: A process for fluorination of borohydride salts including providing a reaction medium comprising HF and a superacid. A borohydride salt compound is added to the reaction medium. The borohydride salt is reacted with the with the reaction medium under conditions to form a fluorinated borohydride salt. In addition, reactor vessels may be provided for reacting the HF, superacid additive and borohydride that are fabricated from materials resistant to superacid compositions.Type: ApplicationFiled: December 6, 2006Publication date: June 12, 2008Inventors: Wade H. Bailey, William Jack Casteel, Sergei Vladimirovich Ivanov, Xukun Luo
-
Publication number: 20080102279Abstract: A borate for a near-infrared ray absorption material, having an anion represented by the formula (1): [BR1mR24?m]? (wherein R1 represents an aryl group having an electron withdrawing group; R2 represents an organic group, a halogen group or a hydroxyl group; and m is an integer in the range of 1 to 4) is provided. The borate of the present invention enables to improve durability, in particular, heat resistance and moisture resistance of a near-infrared ray absorbing dye.Type: ApplicationFiled: January 30, 2006Publication date: May 1, 2008Applicant: NIPPON SHOKUBAI CO., LTD.Inventors: Akio Ito, Satoshi Ishida, Toshiya Iida, Takako Ishii, Nobuhiro Nobayashi
-
Patent number: 7339081Abstract: A process for preparing bromo-1-oxypentafluorosulfanylbenzene is provided, the process including the step of brominating pentafluorosulfanyloxybenzene with a bromination agent to provide the bromo-1-oxypentafluorosulfanylbenzene. The process is more effective than prior art processes for preparing such compounds.Type: GrantFiled: July 10, 2006Date of Patent: March 4, 2008Assignee: Air Products and Chemicals, Inc.Inventors: Robert George Syvret, Gauri Sankar Lal
-
Patent number: 7329781Abstract: The present invention relates to a method of preparing main group boryl compounds by reacting main group hydrides with hydroborating reagents in the presence of a transition metal catalyst.Type: GrantFiled: February 21, 2006Date of Patent: February 12, 2008Inventors: Stephen A. Westcott, Jonathan D. Webb, Daniel I. McIsaac, Christopher M. Vogels
-
Patent number: 7321048Abstract: A method of purifying an organometallic compound by heating the organometallic compound in the presence of a trialkyl aluminum compound and a catalyst.Type: GrantFiled: November 17, 2006Date of Patent: January 22, 2008Assignee: Rohm and Haas Electronic Materials LLCInventors: Deodatta Vinayak Shenai-Khatkhate, Ronald L. DiCarlo, Jr.
-
Patent number: 7279603Abstract: The present invention relates to the use of boron and aluminum compounds in electronics, in particular as electron transport material, as host material of the emission layer and as hole blocking material, in each case in phosphorescent OLEDs, and also to layers produced therefrom in phosphorescent OLEDs.Type: GrantFiled: May 18, 2006Date of Patent: October 9, 2007Assignee: Merck Patent GmbHInventors: Philipp Stössel, Hubert Spreitzer, Heinrich Becker, Jacqueline Drott
-
Patent number: 7247686Abstract: A solid cocatalyst for olefin polymerization in which an ion-containing compound comprising a cation expressed by [R4M]+, wherein the group R are each individually selected from the group consisting of hydrogen atom and a substituted or non-substituted hydrocarbon group having from 1 to 30 carbon atoms with the exception of an aryl group; two or more groups R may form a ring by bonding with one another; at least one of the groups R is a hydrocarbon group having from 1 to 30 carbon atoms with the exception of an aryl group; and M represents nitrogen or sulfur, and a non-coordinating anion expressed by [A] said ion-containing compound is chemically bonded to a fine particulate carrier is used.Type: GrantFiled: October 17, 2002Date of Patent: July 24, 2007Assignees: Basell Polyolefine GmbH, SunAllomer Ltd.Inventors: Satoru Ishigaki, Shinji Hinokuma
-
Patent number: 7230074Abstract: Peptide inhibitors of dipeptidyl-aminopeptidase type IV (DP-IV) are provided. The peptide inhibitors have an isomeric purity of about 96–99 percent. The peptide inhibitors include one or more amino acids covalently coupled to boroproline moiety. The compounds are useful as DP-IV inhibitors, in vivo and in vitro.Type: GrantFiled: February 10, 2004Date of Patent: June 12, 2007Assignee: Trustees of Tufts CollegeInventors: William W. Bachovchin, Andrew G. Plaut, George R. Flentke
-
Patent number: 7211636Abstract: An ionic compound comprising a cationic portion having a hydroxyl group and/or a carboxylic acid group and an anionic portion of the formula (1): [BR4]???(1) wherein R may be the same or different and represents a phenyl group substituted with F or CF3. Preferably, the anionic portion is [B(C6F5)4]?, [B(C6H4CF3)4]? or [B(C6H3F2)4]?. In other aspects, a radiation polymerization initiator and a resin composition comprising the ionic compound are provided. A resin composition prepared by using the radiation polymerization initiator generates a small amount of outgas during reaction and has excellent reactivity and transparency.Type: GrantFiled: June 22, 2005Date of Patent: May 1, 2007Assignee: Mitsui Chemicals, Inc.Inventors: Yugo Yamamoto, Yasushi Mizuta
-
Patent number: 7205441Abstract: Fluoroaryl magnesium halide is reacted with a boron compound so that a molar ratio of the fluoroaryl magnesium halide to the boron compound is not less than 3.0 and not more than 3.7, so as to produce a tetrakis (fluoroaryl) borate.magnesium compound. With this method, there occurs no hydrogen fluoride which corrodes a producing apparatus and requires troublesome waste water treatment.Type: GrantFiled: May 8, 2003Date of Patent: April 17, 2007Assignee: Nippon Shokubai Co., Ltd.Inventors: Ikuyo Ikeno, Toshimitsu Moriguchi, Hitoshi Mitsui, Toshiya Iida
-
Patent number: 7179817Abstract: Compounds represented by formula (I), prodrugs thereof and salts thereof, and pharmaceutical compositions comprising the same as an active ingredient (wherein each symbol has the meaning as defined in the specification.).Type: GrantFiled: May 9, 2002Date of Patent: February 20, 2007Assignee: ONO Pharmaceutical Co., Ltd.Inventors: Takuya Seko, Masahiko Terakado, Hiroshi Kohno, Shinya Takahashi
-
Patent number: 7161040Abstract: This invention relates to an improved method for making unsubstituted carborane anions and monosubstituted carborane anions of formula: (R—CBn—Hm?)? where n is an integer ranging from 5 to about 11 and m? is an integer ranging from 5 to 16 where the relative values of n and m? depend upon the exact structure of the carborane and the presence of a non-hydrogen substituent. m as used herein is an integer ranging from 5 to 16. When R is hydrogen the anion is unsubstituted. When R is a halogen, a phenyl, a substituted phenyl group, such as fluorophenyl group, or any other substituent, the carborane is substituted. The method is particularly useful for preparation of twelve-vertex carborane anions R—CB11H11?, where R is a defined above, and is specifically useful for preparation of the unsubstituted carborane CB11H12-??, where R is H.Type: GrantFiled: April 1, 2002Date of Patent: January 9, 2007Assignee: The Board of Regents of the University and Community College System of Nevada on Behalf of the University of Nevada RenoInventors: Andreas Franken, Benjamin T. King, Josef Michl
-
Patent number: 7145040Abstract: The present invention provides process useful for the preparation of intermediates which are useful in the preparation of amino acids useful in preparing peptide receptor modulators, for example agonists or partial agonists of such peptide receptors. Such peptide receptor modulators include, for example glucagon like peptide-1 receptor modulators which are useful for the amelioration of the diabetic condition.Type: GrantFiled: June 30, 2005Date of Patent: December 5, 2006Assignee: Bristol-Myers Squibb Co.Inventors: Arvind Mathur, K. Selva Kumar
-
Patent number: 7115539Abstract: A metal compound obtained by a process comprising the step of contacting, in a specific ratio, a compound represented by the formula M1L1r, a compound represented by the formula R1s?1TH, and a compound represented by the formula R24?nJ(OH)n; a catalyst component for addition polymerization comprising the metal compound; a catalyst for addition polymerization using the catalyst component; and a process for producing an addition polymer using the catalyst.Type: GrantFiled: January 9, 2004Date of Patent: October 3, 2006Assignee: Sumitomo Chemical Company LimitedInventors: Kazuo Takaoki, Hideki Oshima, Makoto Satoh
-
Patent number: 7087780Abstract: The liquid ethereal medium or liquid hydrocarbyl medium of a solution or slurry of an alkali metal tetrakis(Faryl)borate is substituted with at least one halogenated hydrocarbon, without isolating the alkali metal tetrakis(Faryl)borate, to form a new slurry or solution. At least a portion of the new solution is mixed together with a salt selected from a) a protic ammonium salt, b) an onium salt, and c) a triarylmethyl salt, to produce a protic ammonium tetrakis(Faryl)borate, an onium tetrakis(Faryl)borate, or a triarylmethyl tetrakis(Faryl)borate.Type: GrantFiled: June 24, 2004Date of Patent: August 8, 2006Assignee: Albemarle CorporationInventors: John Y. Lee, Rajeev S. Mathur
-
Patent number: 7078546Abstract: The compound 1,2-bis(9-bora-1,2,3,4,5,6,7,8-octafluorofluorenyl)-3,4,5,6-tetrafluorobenzene, analogs of the compound, and methods for making the compound and its analogs.Type: GrantFiled: April 2, 2004Date of Patent: July 18, 2006Assignee: University Technologies International Inc.Inventors: Warren Edward Piers, Preston A. Chase, Lee Douglas Henderson
-
Patent number: 7067653Abstract: The invention describes the synthesis of a panel of novel carbon-carbon linked carboranyl-containing 5,10,15,20-tetraphenylporphyrins bearing 25–44% boron by weight. In certain embodiments, a phenyl porphyrin compound has a carboranyl group attached to the phenyl group by a carbon-carbon linkage, wherein the phenyl group corresponds to the following formula where R7 through R11 are hydrogen, a carboranyl group, or are selected from the group consisting of hydroxyl, NMe3+, PMePh2+, PO(OH)2, SO3H, COOH, and NH2. In this embodiment, the carboranyl group is attached to the phenyl group by a carbon-carbon linkage, either one or two of R7 through R11 are other than hydrogen; and the phenyl porphyrin compound contains at least one phenyl group having at least one of said carboranyl groups.Type: GrantFiled: May 9, 2001Date of Patent: June 27, 2006Assignee: The Regents of the University of CaliforniaInventors: Maria Da Graca H. Vicente, Shankar Jayaram Shetty, Laurent Jaquinod, Kevin M. Smith
-
Patent number: 6992224Abstract: Present invention relates to a process for the manufacture of fluorinated alcohols as well as borates which are employed in the manufacture of the fluorinated alcohols. Fluorinated alcohols of the formulae HOCHRCF(CF3)CHFCF(CF3)2 and HOCHRCF(CF(CF3)2)CHFCF3, HOCHRCF(CF2CF3)CH(CF3)2 and HOCHRC(CF3)2CHFCF2CF3 are made by heating a mixture of a borate of the formula (RCH2O)3B, wherein R?H or a C1 to C7 alkyl group, with perfluoro-4-methyl-2-pentene or perfluoro-2-methyl-2-pentene and a free-radical initiator to form a mixture of borates, optionally separating the mixture of borates from any reactants, solvents, and by-products; hydrolyzing the mixture of borates to form a hydrolysis product mixture; and separating the alcohols from the hydrolysis product mixture.Type: GrantFiled: May 12, 2004Date of Patent: January 31, 2006Assignee: Honeywell International Inc.Inventors: Michael Van Der Puy, Jingji Ma, George J. Samuels, Leonard M. Stachura
-
Patent number: 6924269Abstract: An enzyme is inhibited by presenting the enzyme with a boron containing structure having a tetrahedral boron atom covalently bound to four ligands. Particularly preferred enzymes include prostaglandin endoperoxide synthase (COX-1 and COX-2), and particularly preferred structures include a ligand that confers at least 80-fold selectivity of COX-2 inhibition over COX-1 inhibition. Consequently, further methods are directed towards induction of apoptosis in a cell and methods of reducing pain.Type: GrantFiled: December 4, 2002Date of Patent: August 2, 2005Assignee: VDF Futureceuticals, Inc.Inventors: Dusan Miljkovic, Pietrzkowski Zbigniew
-
Patent number: 6911551Abstract: The present invention relates to substituted boron or aluminum spiro compounds and their use in the electronic industry. The compounds of the invention are used as electron transport material, hole blocking material and/or as host material in organic electroluminescence and/or phosphorescence devices, as electron transport material in photocopiers, as electron acceptor or electron transport material in solar cells, as charge transport material in organic ICs (circuits) and in organic solid-state lasers or organic photodetectors.Type: GrantFiled: December 20, 2001Date of Patent: June 28, 2005Assignee: Covion Organic Semiconductors GmbHInventors: Philipp Stössel, Hubert Spreitzer, Heinrich Becker, Jacqueline Drott
-
Patent number: 6909008Abstract: An activator for olefin polymerization catalysts is disclosed. One aspect of the activator is that it comprises a group-13 central atom connected to at least one fluorinated aryl ring that is itself substituted with a silyl acetylenic group. Some embodiments employ a neutral activator and others employ the activator as an anion coupled with a ligand-abstracting cation. These activators are discrete molecules.Type: GrantFiled: October 29, 2002Date of Patent: June 21, 2005Assignee: ExxonMobil Chemical Patents Inc.Inventor: George Rodriguez
-
Patent number: 6875737Abstract: Synthetic crosslinking homobivalent and heterobivalent compounds have been designed and developed. These compounds are low in molecular weight, have antagonistic or agonistic activity, and induce the association between two identical or similar natural receptors (homobivalent compounds) or induce the association between two different natural receptors (heterobivalent compounds).Type: GrantFiled: April 9, 1999Date of Patent: April 5, 2005Assignee: Trustees of Tufts CollegeInventor: William W. Bachovchin
-
Patent number: 6867298Abstract: The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or amine moiety and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In additional embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between a nitrogen atom of an acyl hydrazine and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In other embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of a nitrogen-containing heteroaromatic, e.g., indole, pyrazole, and indazole, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate.Type: GrantFiled: May 8, 2003Date of Patent: March 15, 2005Assignee: Massachusetts Institute of TechnologyInventors: Stephen L. Buchwald, Artis Klapars, Jon C. Antilla, Gabriel E. Job, Martina Wolter, Fuk Y. Kwong, Gero Nordmann, Edward J. Hennessy
-
Patent number: 6861384Abstract: A process for preparing salt-like compounds of the formula (1), (C6R115)3MR2??(I) where R1 are identical or different and are each a hydrogen atom, a halogen atom, C1-C20-alkyl, C6-C14-aryl, C1-C10-alkoxy, C2-C10-alkenyl, C7-C20-arylalkyl, C7-C20-alkylaryl, C6-C10-aryloxy, C1-C10-haloalkyl, C6-C10-haloaryl, C2-C10-alkynyl or C3-C20-alkylsilyl, M is an element of main group III of the Periodic Table of the Elements, and R2 is a substituted or unsubstituted heterocycle, and the use of such compounds in catalyst systems for preparing polyolefins.Type: GrantFiled: September 10, 2003Date of Patent: March 1, 2005Assignee: Basell Polyolefine GmbHInventors: Jörg Schottek, Gerhard Erker, Gerald Kehr
-
Patent number: 6855848Abstract: A process for preparing bisallylboranes of the formula (I) by reacting a diene with sodium borohydride in the presence of an oxidant: in an inert solvent, with the borane generated in situ reacting selectively with the diene to form the bis(allyl)borane of the formula (I) and the substituents R1 to R6 having the following meanings: R114 R6 are H, aryl or substituted or unsubstituted C1-C4-alkyl or two radicals R may be closed to form a cyclic system. As oxidant, it is possible to use, for example, alkyl halides or dialkyl sulfates. In a particularly preferred embodiment, the diene used is 2,5-dimethylhexa-2,4-diene (R1, R2, R5, R6=methyl, R3, R4=H).Type: GrantFiled: August 28, 2003Date of Patent: February 15, 2005Assignee: Clariant GmbHInventors: Stefan Scherer, Alexei Kalinin, Victor Snieckus
-
Patent number: 6841635Abstract: Disclosed are internally blocked borates useful for polymerizable compositions, and polymerizable adhesives made therewith. The internally blocked borates have general structures: wherein X represents —CHR6—, oxygen or sulfur; n is an integer; R1, R2, R3, R4, R5, and R6 are independently selected, for example, from unsubstituted and substituted C1-C10 alkyl, alkylene groups, or aryl groups, including other embodiments further defined, and M is a counter ion with positive charge m.Type: GrantFiled: September 9, 2003Date of Patent: January 11, 2005Assignee: Lord CorporationInventors: Jonathan L. Kendall, Robin F. Righettini, Kirk J. Abbey
-
Patent number: 6831200Abstract: The liquid ethereal medium or liquid hydrocarbyl medium of a solution or slurry of an alkali metal tetrakis(Faryl)borate is substituted with at least one halogenated hydrocarbon, without isolating the alkali metal tetrakis(Faryl)borate, to form a new slurry or solution. At least a portion of the new solution is mixed together with a salt selected from a) a protic ammonium salt, b) an onium salt, and c) a triarylmethyl salt, to produce a protic ammonium tetrakis(Faryl)borate, an onium tetrakis(Faryl)borate, or a triarylmethyl tetrakis(Faryl)borate.Type: GrantFiled: October 3, 2002Date of Patent: December 14, 2004Assignee: Albemarle CorporationInventors: John Y. Lee, Rajeev S. Mathur
-
Publication number: 20040249215Abstract: Powdery mixture containing borate and alkali eat metal, for example, magnesium is prepared. Hydrogen atmosphere is fed to the mixture, for example, from hydrogen gas source. The mixture is reacted in hydrogen atmosphere under pressure below reaction equilibrium pressure where hydride of magnesium can exist in stable.Type: ApplicationFiled: November 25, 2003Publication date: December 9, 2004Inventors: Seijirau Suda, Zhoupeng Li, Yasuyoshi Iwase, Nobuto Morigasaki
-
Publication number: 20040242934Abstract: This invention relates to an improved method for making unsubstituted carborane anions and monosubstituted carborane anions of to formula: (R—CBn—Hm′)− where n is an integer ranging from 5 to about 11 and m′ is an integer ranging from 5 to 16 where the relative values of n and m′ depend upon the exact structure of the carborane and the presence of a non-hydrogen substituent. m as used herein is an integer ranging from 5 to 16. When R is hydrogen the anion is unsubstituted. When R is a halogen, a phenyl, a substituted phenyl group, such as fluorophenyl group, or any other substituent, the carborane is substituted. The method is particularly useful for preparation of twelve-vertex carborane anions R—CB11H11−, where R is a defined above, and is specifically useful for preparation of the unsubstituted carborane CB11H12-??, where R is H.Type: ApplicationFiled: July 2, 2004Publication date: December 2, 2004Inventors: Andreas Franken, Benjamin T King, Josef Michl
-
Patent number: 6825169Abstract: An inhibitory compound having the structure: Group I-Group II. Group I has the structure: where H represents a hydrogen; C represents a carbon; O represents an oxygen; N represents a nitrogen; each R, independently, is chosen from the group consisting of the R groups of an amino acid, including proline; each broken line, independently, represents a bond to an H or a bond to one R group, and each H′ represents that bond or a hydrogen; and p is an integer between 0 and 4 inclusive. Alternatively Group I has the structure: where n is between 0 and 3 inclusive, each G2 and G3 independently is H or C1-3 (one to three carbon atoms) alkyl, G1 is NH3 (H3 represents three hydrogens), (H2 represents two hydrogens), or where G5 and G6 can be NH, H, or C1-3 alkyl or alkenyl with one or more carbons substituted with a nitrogen. G1 bears a charge, and G1 and Group II do not form a covalently bonded ring structure at pH 7.0.Type: GrantFiled: October 15, 1997Date of Patent: November 30, 2004Assignee: Trustees of Tufts CollegeInventors: William W. Bachovchin, Andrew G. Plaut, George R. Flentke
-
Patent number: 6812360Abstract: Bis(fluoroaryl)borane derivative is produced by reacting tris(fluoroaryl)borane with a compound, such as water, ethanol, ammonia and the like, in a hydrocarbon solvent at a molar ratio raging from 1:0.9 to 1:1.1. It is more preferable that the reaction is carried out while the hydrocarbon solvent is distilled off. It is more preferable that hydrocarbon solvent is substantially an aliphatic hydrocarbon solvent. With this arrangement, it is possible to provide a method for producing and isolating the bis(fluoroaryl)borane derivative of a high purity, with ease and at a low cost.Type: GrantFiled: September 9, 2002Date of Patent: November 2, 2004Assignee: Nippon Shokubai Co., Ltd.Inventors: Ikuyo Ikeno, Hitoshi Mitsui, Toshiya Iida, Toshimitsu Moriguchi
-
Publication number: 20040199021Abstract: An activator for olefin polymerization catalysts is disclosed. One aspect of the activator is that it comprises a group-13 central atom connected to at least one fluorinated aryl ring that is itself substituted with a silyl acetylenic group. Some embodiments employ a neutral activator and others employ the activator as an anion coupled with a ligand-abstracting cation. These activators are discrete molecules.Type: ApplicationFiled: April 29, 2004Publication date: October 7, 2004Inventor: George Rodriquez
-
Patent number: 6767654Abstract: This invention relates to a borane derivative represented by the formula (1) and an organic electroluminescent device: wherein R1 to R8 and Z2 are each independently a hydrogen atom, a saturated or unsaturated hydrocarbon group, an aromatic group, a heterocyclic group, a substituted amino group, a substituted boryl group, an alkoxy group or an aryloxy group; X, Y and Z1 are each independently a saturated or unsaturated hydrocarbon group, an aromatic group, a heterocyclic group, a substituted amino group, an alkoxy group or an aryloxy group; substituents of Z1 and Z2 may be united to form a condensed ring; and n is an integer of 1-3; with the provisos that when n is two or more, Z1s may be different from each other; and that cases where n is 1, X, Y and R2 are each methyl, and R8 is hydrogen or substituted boryl and those where n is 3 and Z1 is methyl are excluded.Type: GrantFiled: August 24, 2001Date of Patent: July 27, 2004Assignee: Chisso CorporationInventors: Kouhei Tamao, Shigehiro Yamaguchi, Manabu Uchida, Takaharu Nakano, Toshihiro Koike, Takenori Izumizawa, Kenji Furukawa
-
Patent number: 6766183Abstract: Fluorescent biosensor molecules, fluorescent biosensors and systems, as well as methods of making and using these biosensor molecules and systems are described. Embodiments of these biosensor molecules exhibit fluorescence emission at wavelengths greater than about 650 nm. Typical biosensor molecules include a fluorophore that includes an iminium ion, a linker moiety that includes a group that is an anilinic type of relationship to the fluorophore and a boronate substrate recognition/binding moiety, which binds glucose. The fluorescence molecules modulated by the presence or absence of polyhydroxylated analytes such as glucose. This property of these molecules of the invention, as well as their ability to emit fluorescent light at greater than about 650 nm, renders these biosensor molecules particularly well-suited for detecting and measuring in-vivo glucose concentrations.Type: GrantFiled: December 28, 2001Date of Patent: July 20, 2004Assignees: Medtronic MiniMed, Inc., The Regents of the University of CaliforniaInventors: Joseph C. Walsh, Aaron M. Heiss, Glenn Noronha, David J. Vachon, Stephen M. Lane, Joe H. Satcher, Jr., Thomas A. Peyser, William Peter Van Antwerp, John Joseph Mastrototaro
-
Publication number: 20040110631Abstract: Zwitterionic compositions of matter comprising cations [Ct]+ and anions connected together with substantially rigid fluorinated linking groups are described. These zwitterionic compositions serve as cocatalysts. They activate olefin polymerization catalysts, and can dissolve in aliphatic solvents. Synthesis and polymerization are illustrated.Type: ApplicationFiled: April 24, 2003Publication date: June 10, 2004Inventor: George Rodriguez
-
Patent number: 6743883Abstract: The invention relates to a heat-activated initiator for polymerising and/or cross-linking polyorganosiloxane-type monomers, oligomers and/or polymers with organofunctional groups, comprising a boron derivative of formula (I): (A)xB(R′)y, wherein the symbols R′ are the same or different and represent an alkyl or alkenyl radical in C1-C12, an alkoxy radical in C1-C12, a phenyl radical substituted by at least one electroattractor element, an aryl radical containing at least two aromatic rings such as biphenyl, naphthyl, optionally substituted by at least one electroattractor element, especially a halogen atom (particularly fluorine), or an electroattractor group, especially a CF3, NO2, CN group; and a radical —C2H4—Si(Q)3 with the symbols Q being the same or different and representing an alkyl or alkoxy group in C1 to C10 or a siloxane oligomer with less than 10 silicon atoms. The invention also relates to a corresponding cross-linkable composition and to the uses thereof.Type: GrantFiled: April 25, 2002Date of Patent: June 1, 2004Assignee: Rhodia ChimieInventors: Jean-Marc Frances, Thomas Deforth
-
Patent number: 6740466Abstract: Provided is a photopolymerizable composition which has a high sensitivity to not only ultraviolet light but also to visible to infrared light.Type: GrantFiled: October 2, 2000Date of Patent: May 25, 2004Assignee: Fuji Photo Film Co., Ltd.Inventors: Hirotaka Matsumoto, Masanobu Takashima, Shintaro Washizu, Koichi Kawamura, Tadahiro Sorori
-
Publication number: 20040097745Abstract: The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products.Type: ApplicationFiled: April 1, 2002Publication date: May 20, 2004Inventors: Robert H. Grubbs, Arnab K. Chatterjee, Tae-Lim Choi, Steven D. Goldberg, Jennifer A. Love, John P. Morgan, Daniel P. Sanders, Matthias Scholl, F. Dean Toste, Tina M. Trnka
-
Publication number: 20040087842Abstract: The spectroscopic and photophysical properties of fluorescent probes comprising donor-acceptor derivatives comprising the boric acid group or a derivative of boric acid, B(OH)3 (or borate ion, BO(OH)2−1), arsenious acid, H3 AsO3 (or arsenite ion, H2AsO3−1), telluric acid, H6TeO6 (or tellurate ion, H5 TeO6−1) or germanic acid, Ge(OH)6 (or germanate ion, GeO(OH)3−1) are described. Method of using said probes are also provided.Type: ApplicationFiled: May 30, 2003Publication date: May 6, 2004Inventors: Joseph R. Lakowicz, Nicolas Dicesare