Abstract: A medical device system includes an elongated body with a distal end that is configured and arranged for insertion into a patient. A housing is disposed in the distal end of the body. A rotatable magnet is disposed in the housing. At least one magnetic field winding is configured and arranged to generate a magnetic field at the location of the magnet. The magnetic field causes rotation of the magnet at a target frequency. An array of magnetic field sensors is disposed external to the patient. The magnetic field sensors are configured and arranged to sense the location and orientation of the magnet in relation to the array of magnetic field sensors.

Abstract: A medical examination device used for the detection of pre-cancerous and cancerous tissue has an illumination source, a visualization unit, a contacting optical probe, a detector and a process unit. One embodiment of the apparatus includes both a non-contacting macroscopic viewing device (the visualization unit) for visualizing an interior surface of the cervix, as well as a fiber optic wand (contacting optical probe) for spectrally analyzing a microscopic view of the tissue.

Abstract: The invention relates an optical probe (1) suitable for non-linear optics such as two-photon imaging for medical purposes. The probe has an optical guide (2) and a lens system (6) positioned rigidly at an end portion (2a) of the optical guide. Additionally, a housing (3) with a cavity for the optical guide (2) and the lens system (6), the housing having at its distal end a transparent window (4), is comprised in the probe. The optical guide (2) with the lens system (6) is displaceably mounted within the housing, preferably in a transverse direction. Also, the housing (3) has an auxiliary, peripheral optical guide (5) optically connected to the transparent window (4). The invention is advantageous for obtaining an optical probe with a significantly larger collection efficiency. The optical probe may advantageous be applied in connection with two-photon spectroscopy where both ballisitic photons and diffusing fluorescence photons can be used in the detection of an event.

Abstract: The present disclosure relates to methods and devices for surgically manipulating tissue. In general, the methods and devices can include an elongate retractor shaft having a distal retractor tip that is configured to manipulate tissue, for example the tip can be configured to separate muscle and nerve fibers surrounding a vertebra. The elongate retractor shaft can include an illumination source such that at least a portion of the surgical field is illuminated by the device when the device is used in the body. A sensor can also or alternatively be included on the elongate retractor shaft, for example on the blunt retraction tip, such that the sensor can monitor physiological parameters of the tissue in or adjacent to the surgical field.

Abstract: Structured light generated by a projector may be recovered by a camera to determine three-dimensional data about a scene. The structured light signal acquired by the camera may be impaired due to interference from flickering sources of illumination such as lights, electronic displays, and so forth. This optical interference to an image acquisition system, such as a structured light system, is mitigated by modifying operation of a camera by applying a sampling coefficient to the camera's frame rate or by presenting structured light frames during times non-coincident with the interference.

Abstract: A light source for a surgical system includes a broadband light source operable to produce broadband light. The light source further includes a wavelength splitter adapted to split the broadband light into illumination light having a spectral range covering at least a majority of the visible spectrum and surgical light having a spectral range outside of the spectral range of the illumination light. The light source then includes at least one surgical module adapted to control application of the surgical light. The light source also includes first and second coupling optics. The first coupling optics are configured to optically couple the illumination light to an illumination light guide for delivery to a first surgical probe. The second coupling optics are configured to optically couple the surgical light to a surgical light guide for delivery to a second surgical probe.

Abstract: The present invention discloses a rongeur type bone and cartilage removal device incorporating a pistol shaped body exhibiting a forward extending barrel terminating in a powered saw drive including a plurality of blades. A passageway extends through an interior of the barrel and communicates the forward chain drive with a rearward positioned debris collection chamber. A power supply is incorporated into the body and, upon actuating a trigger, closes a circuit with the saw drive and a separate vacuum inducing drive in order to successively excise increments of bone for evacuation through the passageway and into the collection chamber.

Abstract: Methods and apparatus for image processing suitable for use in wireless capsule endoscopy are provided. The image processing techniques exploit characteristic features of endoscopic images to enable low complexity compression. A color space conversion, coupled with lossless predictive coding and variable length coding are employed. Sub-sampling and clipping may also be used. The described image processing can be used both with both white-band imaging and narrow-band-imaging.

Abstract: Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue comprising: a catheter having a distal end and a proximal end; an inflatable balloon disposed about the distal end of the catheter; and an optical housing extending from the distal end of the catheter into the balloon, the optical housing being configured to position inside the balloon a light source for illuminating a tissue outside the balloon and a camera for imaging the illuminated tissue.

Abstract: A method and apparatus for imaging features of a CBD in a patient introduces a fluorescent contrast agent into the CBD. A light source transmits both a visible light and a fluorescent light into a patient's abdominal cavity via the laparoscope. Cameras attached to or integrated into the laparoscope detect visible light images and fluorescent emission light images. The visible light image and fluorescent image signals are processed to combine the fluorescent emission light image signals and visible image signals into a single display signal. The system adjusts the display characteristics, such as color, of the fluorescent emission light image so it contrasts well with the visual light image so the surgeon can easily distinguish between the two images. The display signal is sent to a video monitor where the surgeon views the visible light image and the fluorescent image as a single overlaid image.

Abstract: An illumination optical system unit 26A includes an optical fiber 39A, a fluorescent body 40, a ferrule 60 as a holding member that holds the fluorescent, body 40 and the optical fiber 39A, a cylindrical first sleeve member 61 that covers the outer periphery of the fluorescent body 40, and a protective cover 38 that seals the tip side of the fluorescent body 40. The ferrule 60 holds the optical fiber 39A and the fluorescent body 40, and is inserted into the first sleeve member 61. A magnetic metal film 67 is provided on the surface of a fluorescent body-holding portion 69 of the ferrule 60. The tip of the protective cover 38 and a magnet 75 are allowed to come into contact wife each other to generate magnetic force between those two, so that the fluorescent body 40 comes into close contact with the protective cover 38.

Abstract: To provide excellent illumination over entire range from near view to distant view to achieve clear observation over entire range from near view to distant view. Provided is an endoscope including an imaging optical system 3 provided in insertion portion at a distal end thereof and for observing an object to be observed, and a plurality of illumination optical systems 2a, 2b provided in the insertion portion 1 and for distributing the illuminating light emitted from a light source to the object to be observed, the illumination optical systems being directed in the same direction each other to illuminate the same field of view, wherein at least one of the plurality of illumination optical systems is a first illumination optical system 2a having a convex lens, and at least one of the others is a second illumination optical system 2b having a concave lens.

Abstract: Various embodiments for providing removable and pluggable opto-electronic modules for illumination and imaging for endoscopy or borescopy are provided for use with portable display devices. Generally, various medical or industrial devices can include one or more solid state or other compact electro-optic illuminating elements located thereon. Additionally, such opto-electronic modules may include illuminating optics, imaging optics, and/or image capture devices. The illuminating elements may have different wavelengths and can be time-synchronized with an image sensor to illuminate an object for imaging or detecting purpose or other conditioning purpose. The removable opto-electronic modules may be plugged in on the exterior surface of a device, inside the device, deployably coupled to the distal end of the device, or otherwise disposed on the device.

Abstract: An optical probe system having a probe with an optical guide (G) having a distal end. The optical guide (G) is mounted inside a housing (H) so that the distal end is displaceable with respect to the housing (H). A set of actuators (A), e.g. electromagnetic drive coils, can displace the distal end by application of a drive signal (Vx, Vy). A control unit (CU) generates the drive signal (Vx, Vy) so as to provide a scanning frequency which varies according to an amplitude of the drive signal (Vx, Vy). With such probe system it is possible to scan a field of view with a scanning frequency that varies with the scanning radius. Taking into account the maximum allowable drive current, it is possible to increase scanning speed compared to scanning at the mechanical resonance frequency of the optical system, since small radii can be scanned at a high scanning frequency.

Abstract: Broadband light and narrowband light are simultaneously projected toward a subject. The subject is imaged by a color CCD to obtain a blue signal, a green signal, and a green signal. A base image is generated from the signals of three colors. Based on a luminance ratio B/G between the blue signal and the red signal, a B/G image is generated. A high frequency component is extracted from the B/G image to obtain a superficial-blood-vessel extracted image, and a medium frequency component is extracted from the B/G image to obtain a middle-deep-blood-vessel extracted image. Based on the base image and one of the superficial-blood-vessel extracted image and the middle-deep-blood-vessel extracted image, a blood vessel emphasized/de-emphasized image, in which the superficial blood vessels or the middle-deep blood vessels are emphasized or de-emphasized, is generated. The blood vessel emphasized/de-emphasized image is displayed on a monitor.

Abstract: The invention relates to an intracorporeal probe (10), for example preferably for examining hollow organs or natural or artificially created body cavities in the human or animal body, the probe (10) being designed in the form of a capsule that can be introduced into the body without external connecting elements, comprising an elongate housing (16) and an image pickup unit (26) inside the housing (16) that is designed for optically recording a region (pickup region) outside the probe (10). The image pickup unit (26) is held in a fashion capable of moving inside the housing (16) in order to vary the pickup region by means of such a movement (FIG. 1).

Abstract: A capsule for determining the blood content of living tissue in vivo in a patient to detect tumors. The capsule includes a light source and a light detector for directing light onto the tissue and for receiving interacted light therefrom. By analyzing the interacted light, a determination can be made of the blood content of that tissue. There are various ways of positioning the capsule so that it contacts the tissue in the desired orientation of the light source and light detector. There is also a system for determining the actual contact between the capsule and the tissue. A calibration system is also used that allows a self calibration that can be carried out easily and accurately just prior to the use of the capsule.

Abstract: Methods and devices described herein facilitate improved treatment of body organs.

Abstract: An image-capturing apparatus and a repair method thereof are provided. The image-capturing apparatus includes a lens frame to which one or more lenses are fixed; an image-capturing frame to which an image-capturing device is fixed; and a fixing member for fixing the lens frame and the image-capturing frame to each other without adhering a fitted portion between the lens frame and the image-capturing frame. The repair method for the image-capturing apparatus includes destructing a fixing member for fixing to each other a lens frame to which one or more lenses are fixed and an image-capturing frame to which an image-capturing device is fixed, and releasing fixing between the frames; replacing at least either of the lens frame and the image-capturing frame; and fixing to each other the lens frame and the image-capturing frame.

Abstract: A medical robotic system has a joint coupled to medical device or a slave manipulator or robotic arm adapted to hold and/or move the medical device for performing a medical procedure, and a control system for controlling movement of the joint according to user manipulation of a master manipulator. The control system includes at least one joint controller having a sliding mode control for reducing stick-slip behavior on its controlled joint during fine motions of the joint. The sliding mode control computes a distance to a sliding surface, computes a reaching law gain, and processes the distance and reaching law gain to generate a sliding mode control action that is in absolute value less that a maximum desired feedback control action. The sliding mode control action is then further processed to generate a feedback torque command for the joint motor.

Abstract: An endoscope includes an insert section to be inserted into the body cavity, an illumination window for directing illumination light therethrough and an observation window for observing an illuminated internal portion of the body cavity, arranged at a distal end portion of the insert section, and a blood flow changing section for changing a blood flow of blood flowing through a vessel in a near-surface region of a living organ inside the body cavity by providing one of a temperature change and vibration energy.

Abstract: A system and method for calibrating an object having at least one marker attached thereto, wherein a spatial position of the object is ascertained based on the at least one marker, and an outline, view or geometry of the object is optically detected from at least one side. The detected outline, view or geometry is compared with corresponding outlines, views or geometries of stored pre-calibration data of the object, said pre-calibration data representing a model of the object.

Abstract: A light source device simultaneously produces violet narrowband light and green narrowband light. A complementary color type imaging device of a complementary color type endoscope outputs first to fourth mixed pixel signals. In a complementary color second processor, a matrix operation unit performs a matrix operation of the first to fourth mixed pixel signals, and produces first and second display signals D1 and D2. A mixed color corrector corrects the first and second display signals D1 and D2 on the basis of relational expressions of “D1?=D1?K2×D2” and “D2?=D2?K1×D1”. K1 represents the ratio of a signal value of the second display signal to a signal value of the first display signal under independent application of only the violet narrowband light. K2 represents the ratio of a signal value of the first display signal to a signal value of the second display signal under independent application of only the green narrowband light.

Abstract: Violet light and blue light is applied sequentially to an object. In a wavelength range (380-440 nm) of the violet light, each of reflectances of most-superficial and superficial blood vessels is lower than reflectance of middle-layer blood vessels. In a wavelength range (440-480 nm) of the blue light, the reflectance of the middle-layer blood vessels is lower than those of the most-superficial and superficial blood vessels. Brightness of mucous membrane in a normalized first signal obtained under the violet light is equivalent to that in a normalized second signal obtained under the blue light. A subtraction image is obtained by subtraction between the normalized first and second signals, and superimposed on the first signal. A special image, in which the most-superficial and superficial blood vessels correspond to falling edges and the middle-layer blood vessels correspond to rising edges and the blood vessels are distinguished from each other, is produced.

Abstract: Methods and apparatus for off-axis visualization are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.

Abstract: A video recording and image capture device for documenting surgical procedures that includes a main board for executing a plurality of software, a multimedia interface operable to receive a video signal and process it into an MPEG layer stream, the video interface connected on a first bus to the main board, a hard drive to record an MPEG layer stream as a file, an optical media drive to write an MPEG layer stream as a file, the hard drive and the optical media drive operably connected on a second bus, the bus being vertically stacked and connected to the main board, and a touchscreen interactive for user control, connected to the main board on a second bus to control the video interface.

Abstract: An image display apparatus includes: a storage unit storing in-vivo image data and information associated with the in-vivo image data and related to a position of a capsule endoscope in a subject; an image processing unit performing image processing on the in-vivo image data stored in the storage unit; a display unit displaying an in-vivo image based on the in-vivo image data image-processed in the image processing unit; a position estimating unit estimating an intra-subject position in which an in-vivo image is captured, based on the position-related information; a control unit performing image processing in the image processing unit and position estimation processing in the position estimating unit in parallel; and a reporting unit reporting information indicating that a radiogram interpretation is possible, when image processing in the image processing unit for all the in-vivo image data is completed while processing in the position estimating unit is not completed.

Abstract: The invention concerns an imaging system to monitor at least one surgical instrument in an operative site inside a volume of the body of an animal, comprising: at least one endoscopic camera to obtain endoscopic data on the operative site, at least one ultrasound imaging device to obtain ultrasound data on the operative site, and a processing device to process the endoscopic and ultrasound data. The imaging system further comprising at least three markers intended to be positioned in the operative site, said markers being mobile relative to the instrument, each marker being adapted to be detected both by the endoscopic camera and by the ultrasound imaging device, so as to permit cross-mapping of the endoscopic and ultrasound data by the processing means.

Abstract: A cannula for a patient includes an elongate body having a length of at least 70 cm and a channel extending through the body defining a wall. The cannula includes a wire embodied within at least a portion of the wall. The body has a proximal end, a distal end having a tip opening through which the channel extends and a plurality of side holes through the wall in proximity to the tip for unimpeded flow of blood at the distal end. The cannula includes a barbed fitting at the proximal end. The cannula includes a suture wing for securing the elongated body to the patient. A system for assisting a patient's heart. A method for assisting a patient's heart.

Abstract: A control apparatus controls a bio-optical measurement apparatus which is configured to be inserted into a subject through an endoscopic device and is configured to perform an optical measurement of a biological tissue in the subject. The endoscopic device is configured to capture, by inserting a distal end part of the endoscopic device into the subject, in-vivo images of the subject by an imaging unit provided at the distal end part. The control apparatus includes a position determining unit configured to determine a position of the distal end part in the subject, and a permission signal outputting unit configured to output a permission signal for permitting the bio-optical measurement apparatus to perform the optical measurement based on a determination result by the position determining unit.

Abstract: The present invention is an endoscope device in which a portion of the optical system can be changed using an optical adaptor, provided with: an image pickup member for capturing an image that is input from an optical system that incorporates a reference scope or user scope, and an optical adaptor; a first recording medium that records a first information that includes at least distortion parameters of the reference scope which indicate the optical properties of the reference scope; a second recording medium that records a second information that includes at least distortion parameters of the user scope which indicate the optical properties of the user scope; and a distortion correcting member that corrects distortion in the image captured by the image pickup member when the user scope and the optical adaptor are combined, based on the first information which is read out from the first recording medium and the second information which is read out from the second recording medium.

Abstract: An endoscopic apparatus according to the invention has an illumination unit capable of emitting to a subject first narrow band light having a wavelength band in a blue region and second narrow band light having a wavelength band in a green region, an image pickup unit which picks up a first subject image when the subject in the living body is illuminated with the first narrow band light, and picks up a second subject image when the subject in the living body is illuminated with the second narrow band light, a storage unit which stores the first subject image as a green component and a blue component, and stores the second subject image as a red component and a blue component, and a color tone conversion unit which performs predetermined color conversion processing to form an image of a predetermined object as an image having a predetermined first color.

Abstract: A scanning endoscope apparatus includes a light source section that emits illumination light, an optical fiber that irradiates the illumination light from a distal end to a subject with directivity, a drive element and a scanning drive section that perform scanning by the distal end of the optical fiber, a first light detection section that detects light from a direction of the distal end of the optical fiber, a second light detection section that detects light from an entire scanning range, and an image processing section that forms image information to be outputted to a display section based on a result of addition of a detection result corresponding to an external factor light component in a first light detection result and a second light detection result.

Abstract: An endoscope apparatus comprises an analyzing portion configured, in a folder generating mode for extracting folder generating information regarding generation of a plurality of folders that record a plurality of image data of an inspection object, to analyze an image picked up by an image pickup portion and to extract the folder generating information; a folder generating portion configured to generate a plurality of folders regarding the inspection object based on the folder generating information extracted by the analyzing portion; and an inspection image recording portion configured to record each image data of the inspection object picked up by the image pickup portion in one folder among the plurality of folders generated by the folder generating portion.

Abstract: A capsule-medical-device dedicated power source starter that allows switching, by an application of a magnetic field to a magnetic switch that is provided in an inside of a capsule medical device and has a particular sensitivity direction in the magnetic field, a driving of the capsule medical device from an OFF state to an ON state, includes: an insertion part that is formed in a central axis direction and to which the capsule medical device is inserted so that a longitudinal axis direction of the capsule medical device is along the central axis direction; and a magnetic circuit that generates magnetic force lines which are substantially symmetric about the central axis as an axis of symmetry in any planar surfaces including the central axis of the insertion part.

Abstract: A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.

Abstract: A method of displaying an image of the location of one or more low voltage structures in tissue is provided. The method includes receiving electrical mapping data corresponding to a portion of the tissue. The method further includes generating an image using the electrical mapping data. Electrical mapping values within at least one voltage range having two endpoints that bound the upper and lower limits of the voltage range are distinguishable from electrical mapping values outside the at least one voltage range. The two endpoints are selected to distinguish the one or more low voltage structures of the tissue from other portions of the tissue.

Abstract: In the imaging apparatus according to an aspect of the present invention, the aperture area ratio between the plurality of regions of the multifocal lens is appropriately configured. Thereby, it is configured such that, when a plurality of images are simultaneously imaged via the plurality of regions using the illumination light source, brightness of the image of the subject at an in-focus distance corresponding to one region of the plurality of regions, the image imaged via the one region, the brightness arising from the illumination light, is substantially equal to brightness of the image of another subject at an in-focus body distance corresponding to another region, the image imaged via the other region except the one region, the brightness arising from the illumination light. Accordingly, the subject at any of the distances does not suffer excess or deficient exposure.

Abstract: An in vivo endoscope illuminates tissue using multiple sources. Light from a short-range source exits a tubular wall of the endoscope through a first illumination region that overlaps an imaging region, and the light returns through the imaging region after reflection by tissue, to form an image in a camera. Light from a long-range source exits the tubular wall through a second illumination region that does not overlap the imaging region. The endoscope of some embodiments includes a mirror, and light from an emitter for the short-range source is split and reaches the first illumination region from both sides of an optical axis of the camera. Illuminating the first illumination region with split fractions of light results in greater uniformity of illumination, than illuminating directly with an un-split beam. The energy generated by each source is changed depending on distance of the tissue to be imaged.

Abstract: A miniature ingestible capsule has multiple therapeutic or diagnostic operations that can be performed. These functions are controlled by a combination of an outside control, a pose beacon and through information relayed from an imagining array and transmitter. These functions can be in a separate capsule without an imaging array or within the same capsule with an imaging array. Typically, there is one function performed in addition to imaging. These functions can include suction and spray capabilities, ultrasound sensor, lithotripsy, laser, heat, electrocautery, BICAP, biopsy forceps, a needle knife snare cautery (cold and hot with continuous or pulsed current for cutting and coagulation), with a basket, and fine needle aspiration with various wheels and fins and motors controlled externally and other tools to be used in humans. All of these tools can be attached to a retractable arm. Also, they can be used on an elevator device that lifts them, allowing for an extra 180° of movement.

Abstract: The present invention relates generally to medical devices and methods. The present medical devices comprises a platform comprising a magnetically-attractive material, and a camera coupled to the platform and configured to be moved in at least three degrees of freedom relative to the platform, where the camera's movement in each respective degree of freedom is controlled by a separate actuator coupled to the platform. The medical devices further comprise a housing disposed around at least a portion of the camera, the housing being at least partially transparent, and a wiper arm configured to move relative to the housing.

Abstract: An electronic endoscope system includes a light source device for sequentially emitting plural kinds of light having different wavelength bands, an electronic endoscope for outputting image data of acquired images corresponding to the plural kinds of light sequentially illuminated to a subject tissue containing blood vessels, a setter for setting a blood vessel characteristics amount from the image data, a setter for setting a region of interest in the acquired image based on the amount, an image producer for producing a first oxygen saturation level image representing a distribution of an oxygen saturation level in the blood vessel from the image data, and an image display for displaying in simulated color a second oxygen saturation level image in which the oxygen saturation level within the region of interest is selectively enhanced.

Abstract: An endoscope apparatus includes: a light source device radiating at least one or more illumination lights having a predetermined wavelength band to a subject; a CCD picking up an image of a return light from the subject based on radiation of the illumination light from the light source device; an image processing section outputting a first image signal of a first wavelength band having a peak wavelength of spectral characteristic, between a wavelength band including a maximum value and a wavelength band at a minimum value with regard to an absorption characteristic of living tissue, after image pickup by the CCD; and an observation monitor performing image display on the basis of the first image signal.

Abstract: A signal transmission device includes a transmission unit, a first connection unit, a second connection unit, and a reception unit. The transmission unit sends a transmission signal. The first connection unit includes a first electrode electrically connected to the transmission unit. The second connection unit includes a second electrode that engages with the first connection unit, and, when engaged with the first connection unit, is statically coupled with the first electrode. The reception unit is electrically connected to the second electrode and receives the transmission signal.

Abstract: A connector for connection to terminals of an integrated circuit. The connector consists of a dielectric substrate having a first side and a second side. The connector has wire bond terminals which are attached to the first side of the substrate and configured to receive wire bonds connected to a first set of the terminals of the integrated circuit. The connector also has solder bump terminals, attached to the second side of the substrate so as to be insulated from the wire bond terminals, the solder bump terminals being configured to be coupled via solder balls with a second set of the terminals of the integrated circuit.

Abstract: A medical instrument having a lighting system for illuminating a target area, the system comprising a light source and associated power controller, the system being configured to move from a first illumination mode to a second illumination mode based on a sensed or determined changed condition, such as predetermined temperature and/or change in a scene or brightness signal, or lack of change, from an image sensor that may be associated with the instrument.

Abstract: An endoscope having a single-use disposable illumination and camera module is provided in which an imaging element is disposed within an annular tube of optically transparent material having proximal and distal ends, wherein the proximal end is configured to engage a plurality of LEDS and the distal end has a cross-section in the form of an arc of a circle or ellipse, so that the annular tube serves as a light mixer and diffuser, providing uniform illumination within the field of view of the imaging element. Methods of analyzing and displaying the output of the endoscope also are provided.

Abstract: The endoscope diagnostic apparatus includes a light source emitting white light and two or more kinds of excited light with different center wavelengths for emitting two or more kinds of self-fluorescence from a self-fluorescent material, an imaging unit which receives reflected light of white light to image a normal light image, and receives self-fluorescence emitted from the self-fluorescent material to image self-fluorescent images, and a light source control unit which has compensation coefficients for preventing emission intensity from being lowered depending on the volume of blood when the two or more kinds of excited light are absorbed by blood, and compensates the ratios of emission intensity of the two or more kinds of excited light using the calculated compensation coefficients so as to exclude the influence of absorption of light by blood in each of the two or more kinds of excited light.

Abstract: A system and method for detection of colorimetric abnormalities within a body lumen includes an image receiver for receiving images from within the body lumen. Also included are a transmitter for transmitting the images to a receiver, and a processor for generating a probability indication of presence of colorimetric abnormalities on comparison of color content of the images and at least one reference value.

Abstract: A wide dimming dynamic range and high dimming resolution are obtained without causing a variation in the amount of received light due to pulse illumination light in each line of an imaging element. An imaging device includes a light source emitting light by pulse driving, a light source control unit controlling the amount of emitted light by performing pulse modulation driving of the light source, and an imaging unit including an imaging element, in which a plurality of pixels are arrayed in a horizontal and vertical direction, and performs imaging by driving the imaging element using a rolling shutter method. The light source control unit performs pulse driving of the light source at a timing synchronized with a timing pulse signal having, as a period, 1/p (p is an integer of 1 or more) of the exposure start timing interval when driving the imaging element using the rolling shutter method.