Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: The present invention relates to ultrasound assisted tissue welding, more particularly, to a method and device utilizing ultrasound energy for effective closure and sealing of surgical incisions or other wounds. The device of the present invention comprises an ultrasound generator, an ultrasound transducer, a transducer tip at the distal end of the ultrasound transducer, and a radiation surface. A web such as gauze is placed over the incision. In an embodiment, the device may be used to bring the edges of the tissue to be sealed together as the device applies energy to the tissues. Ultrasonic waves emanating from the radiation surface pass through the web and seal the incision creating a continuous seam. The device may be used with or without additional adhesive materials or therapeutic agents.

Abstract: An adhesive patch for covering a portion of the anatomical surface of a living being, said patch being able to adhere to the skin, and/or a wound on a part of the body, said patch comprising a backing layer and a layer of a skin-friendly adhesive for adhering to the skin, and said patch having a pattern of indentations wherein the indentations are in the form of a pattern of curvilinear indentations shows a flexibility capable of adapting to the contour of a skin surface or a joint that is frequently bent ensuring a snug fit and a safe grip.

Abstract: The present invention relates to wound dressings, particularly for the treatment of medium to severely exudative wounds, and their use in modern wound treatment. As multi-layer wound dressings, these wound dressings contain a carrier layer, an absorbing layer, and a hydrophilic wound contact layer connected to the absorbing layer, wherein the wound contact layer comprises a hydrophilic polyurethane elastomer.

Abstract: The present invention comprises methods and compositions for making a silver-containing antimicrobial hydrophilic material. More particularly, the present invention comprises methods and compositions for stabilized silver antimicrobial devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide, and an active agent. The matrix may be formed into any desired shape for its desired uses.

Abstract: A composite wound dressing apparatus promotes healing of a wound via the use of a micropump system housed within or above a wound dressing member. The micropump system includes a miniature pump that applies a subatmospheric pressure to the wound to effectively draw wound fluid or exudate away from the wound bed without the need for a cumbersome external vacuum source. Hence, the wound dressing and micropump system is portable which allows the patient mobility that is unavailable when an external vacuum source is used. The patient does not need to be constrained for any period of time while exudate is being removed from the wound.

Abstract: Methods, systems, and apparatuses for nanomaterial-enhanced hemostatic medical devices are provided. Hemostatic materials and structures are provided that induce coagulation of blood at a wound/opening caused by trauma, a surgical procedure, ulceration, or other cause. The hemostatic materials and structures may incorporate nanostructures and/or further hemostatic elements such as polymers and/or glass beads. The hemostatic materials and structures may be resorbable. Example embodiments include hemostatic bandages, hemostatic plugs, and hemostatic formulations.

Abstract: An absorbent structure formed from a process of providing water-swellable material that includes water-swellable polymer particles, which are coated with a coating agent. The coating agent is a phase-separating elastomeric material that has a first and second glass transition temperature. The coated water-swellable polymer particles are able to swell without breakage of the coating.

Abstract: Compositions comprising clay minerals and methods for their use in promoting hemostasis are provided. The compositions comprise clay minerals such as bentonite, and facilitate blood clotting when applied to a hemorrhaging wound. Electrospun or electrosprayed materials (e.g. bandages, micron beads, etc.) which include clay minerals, and methods for the treatment of acute hemorrhage, are also provided.

Abstract: A limb wound treatment device is described having a first end, a second end and an interior therebetween for accommodating a treatment gas. The device can include a flexible housing that can be inflated or a rigid housing. The first end can include an inflatable cuff seal for hermetically sealing against the limb being treated. The second end can include a closed end or an access port that is releasably sealed with a clamping mechanism. Further, the device can include a controller that can inflate that housing, inflate the cuff seal and provide treatment gas to the interior, in response to pressures within the cuff seal and the housing. Further, the device can accommodate different types of wound treatments, such as hyperbaric therapy, compression therapy or negative pressure therapy.

Abstract: An epidermal lifting mechanism (10) comprising at least one strip of flexible material (50), first and second end portions (60), a middle portion (70), adhesive material (40), a plurality of resilient spring structures (20, 22, 24) extending through the at least one strip of flexible material, and a flap mechanism (80) integral with the middle portion.

Abstract: A biodegradable microfiber absorbent comprises a substantially homogeneous mixture of at least one hydrophilic polymer and at least one biodegradable polymer. The absorbent can be prepared by an electro hydrodynamic spinning of a substantially homogeneous polymer mixture. Medical dressings for burns and wounds, cavity dressings, drug delivery patches, face masks, implants, drug carriers that comprises at least one microfiber electrospun from a polymer mixture are provided. The dressings can have variable water vapor penetration characteristics and variable biodegradation times.

Abstract: A vacuum bandage is provided for use with a wound having a wound surface. The bandage is connectable to a vacuum source and includes a wound dressing member having a wound contacting surface, a top surface, and a port configured for communication with the vacuum source. The wound dressing member further includes holes in the wound contacting surface configured for communication with the wound surface of the wound and a passageway between the port and each hole. The vacuum bandage further includes a pack adjacent to the top surface of the member. The pack may include an aperture positioned about the port.

Abstract: A method and apparatus for the introduction to a wound under negative pressure therapy of a wound healing agent, generally comprises a foam pad (11) for insertion substantially into a wound site (12), and a wound drape (13) for sealing enclosure of the foam pad at the wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of fluid drainage. Additionally, the foam pad is predisposed, through grafting or other techniques known to those of ordinary skill in the art, with basic fibroblast growth factor (bFGF), anti-microbial or other factors, also known to those of ordinary skill in the art, for the promotion of increased wound healing.

Abstract: Articles are provided which mask the appearance of stains. The articles utilize a metalized substrate formed from a substrate and a discontinuous metal layer deposited thereon, the metalized substrate having a gloss of at least about 2 gloss units when measured at an angle of illumination of 20°.

Abstract: A wound dressing defines bodyside and backside surfaces. The dressing comprises a backing layer defining a center portion and a border portion surrounding the center portion. An absorbent core is connected to a surface of the backing layer within the center portion The absorbent core may be exposed along a bodyside surface of the wound dressing, or various adhesives and non-adhesive substrates may be applied along a surface of the absorbent core so as to define part of the bodyside surface of the wound dressing.

Abstract: A wound dressing defining skin facing areas having different degrees of skin adherence. The dressing comprises a backing layer defining a center portion and a border portion surrounding the center portion. An absorbent core is connected to a surface of the backing layer within the center portion. The absorbent core may be exposed along a proximal surface of the wound dressing, or various adhesives and non-adhesive substrates may be applied along a proximal surface of the absorbent core.

Abstract: The invention relates to a medical dressing having an elastic material for encircling about a body member, an elastomer attached to the elastic material and adapted to directly contact a wound on the body member, and where the elastomer includes an additive for treating the wound, wherein the elastic material applies compressive force to the elastomer and wound as the elastic material encircles the body member.

Abstract: Filament-reinforced composite fibers made from a plurality of filaments and a matrix are useful in forming medical devices such as sutures and meshes.

Abstract: A packaged article including an adhesive-sided article, such as an adhesive bandage, and packaging formed of top and bottom backing sheets with a release layer disposed either directly on the bottom backing sheet facing the adhesive side of the article or on release paper carried on the bottom backing sheet. The facing surfaces of the top backing sheet and bottom backing sheet peripherally surrounding the adhesive-sided article have cohesive surfaces. An adhesive strip, preferably a double-sided adhesive strip, attaches the non-adhesive side of the adhesive-sided article to the top backing sheet. The top sheet is used as an applicator for placing the article onto a target surface, such as a patient's skin. The cohesive surface of the top sheet surrounding the article does not adhere to the target surface. A release layer applied directly on the bottom backing sheet eliminates additional material and waste.

Abstract: A wound dressing comprising an absorbent pad, an adhesive layer, and a backing layer is described, along with a dressing support layer configured to retain and deliver the wound dressing to a wound, the dressing support layer having a radial configuration that forms a plurality of alternating covered and uncovered portions of the backing layer along the perimeter of the wound dressing.

Abstract: Thus, systems and methods for a debriding wound vacuum may include a sponge for application to a wound, a flexible sheet for covering and sealing the wound, and a bladder. The bladder may be in fluid communication with at least a portion of the sponge. The bladder preferably contains a debridement substance. A negative pressure device may form part of the system and may be used to apply negative pressure via a hollow tube to the sponge. The negative pressure device may be adapted to apply negative pressure to the sponge via the hollow tube in order form a seal between the flexible sheet and the wound. The systems may also include microelectronic mechanical valves for releasing the debridement substance from the bladder.

Abstract: Superabsorbent foam comprising superabsorbent fiber and/or fruit fiber, processes for producing superabsorbent foam having improved wet strength by foaming a crosslinkable aqueous mixture comprising at least 50 mol % neutralized acid-functional monoethylenically unsaturated monomer or at least one basic polymer, crosslinker, superabsorbent synthetic fiber and/or fruit fiber and at least one surfactant and subsequently polymerizing the monomer in the foamed mixture or crosslinking the basic polymer to form a hydrogel foam and use of the thus obtainable foam in hygiene articles to absorb body fluids, in dressing material to cover wounds, as a sealing material, as a packaging material, as a soil improver, as a soil substitute, to dewater sludges, to thicken waterborne paints or coatings in the course of disposing of residual quantities thereof, to dewater water-containing oils or hydrocarbons or as a material for filters in ventilation systems.

Abstract: A wound dressing includes an absorbent core which defines opposed proximal and distal surfaces, and peripheral edges delimiting the proximal and distal surfaces. The absorbent core has a central portion with a first thickness, and a beveled portion surrounding the central portion and extending to the peripheral edges. The beveled portion has a second thickness that is less than the first thickness corresponding to the central portion.

Abstract: A multi-layered wound dressing includes a moisture-retaining portion for enhancing the healing of a wound. The wound dressing includes an intermediate layer that has both water soluble and water insoluble fibers. An apparatus that includes a cutting tool and a reservoir of liquid to pre-moisten a portion of the dressing may be used to manufacture the dressings.

Abstract: Absorbable tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan.

Abstract: Absorbable tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan.

Abstract: A wound dressing apparatus for use in subatmospheric pressure therapy includes an outer member dimensioned for positioning relative to a wound bed and defining an internal reservoir, a port associated with the outer member and in communication with the internal reservoir for applying subatmospheric pressure to the internal reservoir to facilitate treatment of the wound bed and removal of fluid therefrom, an inner member at least partially positionable within the wound bed and confined within the outer member, and an adhesive agent in contact with a peripheral section of the outer member to facilitate attachment of the peripheral section to the periwound tissue. The adhesive agent is preferably substantially devoid of contact with the inner member. In one embodiment, a layer of adhesive material is disposed on the peripheral section of the outer member.

Abstract: A wound dressing comprises a wound-contacting layer composed of a mixture of honey and a moisture-absorbing agent; a water-permeable fabric backing layer; and an intermediate layer comprising water-permeable fabric impregnated with a mixture of honey and a moisture-absorbing agent.

Abstract: Methods for producing biocompatible compositions are provided. The biocompatible compositions include an isocyanate-functional polyurethane prepolymer in combination with a foam control agent. The foam control agent decreases the formation of bubbles and/or foam in the biocompatible composition, thereby enhancing the physical properties of the biocompatible composition. The presence of the foam control agent does not compromise the strength of the biocompatible composition. The compositions prepared by the methods of the present disclosure may be used as adhesives or sealants for medical/surgical uses.

Abstract: A dressing having a flexible sleeve shaped to accommodate a substantially cylindrical body portion, the sleeve having a lining which is substantially non-adherent to the body part being bandaged and having a peripheral securement means which attaches two peripheral portions to each other without those portions being circumferentially adhered to the sleeve portion.

Abstract: A method of the invention is provided for making a wound dressing including an absorbent core having proximal and distal surfaces, and a liquid impervious, vapor permeable backing layer extending over the distal surface of the absorbent core. The backing layer has a portion defining a compliant element disassociated and outwardly extending from the distal surface of the absorbent core. The method includes the steps of securing a border portion of the backing layer to a border portion of the absorbent core located near the periphery thereof, connecting a central portion of the backing layer to a central portion of the absorbent core, and forming the compliant element by drawing a portion of the backing layer away from the absorbent core.

Abstract: The present invention is directed to methods of using implantable bioabsorbable non-woven self-cohered web materials having high degrees of porosity, particularly at anastomotic sites. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.

Abstract: A wound dressing includes an absorbent core having opposed proximal and distal surfaces and a discrete skin adherent, apertured facing layer having a distal surface secured to the proximal surface of the absorbent core. The facing layer includes portions of a proximal surface thereof having different degrees of skin adherence.

Abstract: The invention relates to an absorbent article for application to human or animal skin surfaces in the region of wounds, consisting of an outer covering (2) which is permeable for liquid substances, and of an inner layer (1) which is surrounded by the covering (2) and which consists essentially of a mixture of an amount of strongly osmotically active substances with an amount of osmotically comparatively weak or osmotically inactive substances, such as cellulose. The inner layer (1) is filled with osmotically active substances in such a way that it is possible to exert on a wound, with the wound fluids contained therein, an osmotic pressure via which the wound fluid can be removed from the organism to be treated, and thus it is possible to assist both in the surfaced wound region and in the depth of the tissue a normal interstitial hydration of tissue by directing endogenous fluids in their direction of flow to the patient's skin surface into the absorbent article, and keeping them there.

Abstract: A coating composition is described for the anti-adhesive coating of wound dressings, comprising a nanosol that contains silica and at least one hydrophobic organic silicon compound, anti-adhesive layers prepared therefrom, coated wound dressings and methods for their manufacture.

Abstract: A fabric substrate suitable for lining between a cast and a person. The fabric substrate includes a pair of opposing faces formed by pillar and inlay stitches. The fabric is constructed at least in part of hydrophobic, water-resistant yarns configured to provide enhanced water resistance and sufficient stretch in both a length and width direction to facilitate conforming the undercast liner around the anatomical shape without wrinkling during application. An intermediate tying layer spans between the opposing faces, and the tying layer includes elastic yarns stitched in a V stitch pattern such that the elastic yarns extend between one opposing fabric face and the other face.

Abstract: Systems and methods provide intraluminal delivery of a bandage structure within a body lumen or hollow body organ.

Abstract: The present disclosure relates to a film dressing having a polymer film and an application system for permitting an improved ease of use of said film dressing. The application system is located on the first side of the polymer film and has at least one first and one second supporting film. At least one first grip strip is formed on the first supporting film and at least one second grip strip is formed on the second supporting film. At least the first grip strip has a grip surface that enables the grip strip to be grasped and the first grip strip at least partially overlaps the second grip strip.

Abstract: An absorbent fibrous material comprising fibres prepared by melt spinning, solvent spinning, dry spinning or electro spinning of a polymer composition having a water absorption capacity of at least 10 g/g polymer composition and comprising a thermoplastic hydrophilic block copolymer as well as wound dressings comprising such absorbent fibrous material.

Abstract: An abdominal wound dressing and methods of use are described that enable the application of negative pressure to the wound site in a healing manner while also limiting the formation of adhesions that would prevent the removal of the dressing. The dressing comprises a layer of porous foam material enclosed by sheets of elastomeric material punctuated by a number of appropriately placed holes. Multiple layers of porous foam may also be used. A suction tube connector is provided on an upper surface of a layer of foam for connection to a negative pressure source. At least one layer of foam is enclosed in elastomeric material and is placed in direct contact with the tissue within the open wound. Fluids are drawn by negative pressure through the holes positioned in the elastomeric envelope and through the foam.

Abstract: A wound dressing including an absorbent core defining opposed proximal and distal surfaces, the distal surface of the absorbent core defining a central portion, a border portion and an intermediate portion interposed between the central and border portions. The backing layer defines at least one compliant element disassociated from the distal surface of the absorbent core and including at least one ridge extending outwardly relative to the distal surface of the absorbent core.

Abstract: A medical closure screen device for a separation of first and second tissue portions is provided, which includes a mesh screen comprising tubular vertical risers, vertical strands with barbed filaments, and horizontal spacers connecting the risers and strands in a grid-like configuration. An optional perimeter member partly surrounds the screen and can comprise a perimeter tube fluidically coupled with the vertical risers to form a tubing assembly. Various input/output devices can optionally be connected to the perimeter tube ends for irrigating and/or draining the separation according to methodologies of the present invention. Separation closure, irrigation and drainage methodologies are disclosed utilizing various combinations of closure screens, tubing, sutures, fluid transfer elements and gradient force sources. The use of mechanical forces associated with barbed strands for repositionably securing separated tissues together is disclosed.

Abstract: A flexible medical closure screen for closing a separation of first and second tissue portions is provided, which includes a mesh screen comprising tubular vertical risers, vertical strands with barbed filaments, and horizontal spacers connecting the risers and strands in a grid-like configuration. An optional perimeter member partly surrounds the screen and can comprise a perimeter tube fluidically coupled with the vertical risers to form a tubing assembly. Various input/output devices can optionally be connected to the perimeter tube ends for irrigating and/or draining the separation according to methodologies of the present invention. Separation closure, irrigation and drainage methodologies are disclosed utilizing various combinations of closure screens, tubing, sutures, fluid transfer elements and gradient force sources. The use of mechanical forces associated with barbed strands for repositionably securing separated tissues together is disclosed.

Abstract: A disposable wound measuring device for making simultaneous three-dimensional (length, width and depth) measurements of a wound or ulcer to facilitate wound care assessment and healing that includes a flexible, clear plastic planar card or member superposed on the wound and having a centrally located aperture and concentric circles radially arranged about the aperture, and an elongated depth gauge insertable through the aperture and incrementally adjustable either vertically or obliquely through the aperture and relative to the wound surface and the plastic member for making a wound depth measurement with the depth gauge being retained in position by a plurality of beads equidistantly spaced along the gauge and slightly larger in diameter than the aperture thereby self-retaining the depth gauge in a particular position for making the wound depth measurement.

Abstract: A method of inhibiting and/or treating wounds on a patient's skin includes applying a covering of collodion over an area on the patient's skin which is prone to formation of an ulcer or to a wound on the patient's skin where a wound has formed. The covering of collodion may contain an active ingredient to stimulate healing of the area covered by the collodion.

Abstract: A wound treatment device comprises a wound surface contacting plug (10) and a cover (24) for covering the wound surface (22) and the plug (10), wherein said plug (10) consists of a flat textile isolating material comprising at least one first surface layer (12), one second surface layer (14) and one intermediate space (18) arranged between said surface layers (12, 14). At least the first surface layer (12) is provided with a biocompatible surface and a structure which enables a liquid to pass and prevents a wound tissue from growing in said structure. The intermediate space (18) is provided with isolating threads (16) elastically holding the first surface layer (12) and the second surface layer at a certain distance from each other.

Abstract: A wound dressing defining skin facing areas having different degrees of skin adherence. The dressing comprises a backing layer defining a center portion and a border portion surrounding the center portion. A carrier layer is secured to the border portion of the backing layer within the border portion and includes a first skin adherent facing layer. An absorbent core is connected to a surface of the backing layer within the center portion and a second skin adherent facing layer is disposed along a surface of the absorbent core. The first facing layer has greater skin adhesive properties than the second facing layer.

Abstract: A transcutaneous access shield with an instrument opening and surrounding wall to prevent infection during surgical and other medical procedures. The shield resists the entry of microbes from the skin at the body access point. A shield positioner and skin hook can be used to improve placement of the shield.

Abstract: The present invention relates to a medicinal product with a textile component such as a wound compress having a surface containing a multiplicity of openings arranged in at least two hole patterns. The diameter of one opening of one hole pattern deviates from the diameter of an opening of another hole pattern by about at least a factor of 5. Better wound healing is achieved by adapting the structural and mechanical characteristics of the medicinal product to the characteristics of the target tissue.