Abstract: The invention relates to an assembly that includes an infusion set and a patch intended for receiving a pump for the transcutaneous administration of a product, said patch including an adhesive portion and a non-adhesive portion, the assembly being characterized in that said set includes patch-guiding elements and sliding elements intended for sliding along the guiding elements.

Abstract: An autoinjector device includes an elongate housing containing a syringe or cartridge having an internal piston for expressing a dose from the syringe or cartridge. A drive mechanism includes a drive member engaging the piston and a drive spring acting on the drive member. A side-operated trigger arrangement includes a retention element movably mounted in the housing from a retaining position in which the drive member is kept in a cocked condition, and a release position in which the drive member may more forwardly under spring pressure. An outer sleeve is mounted on the housing movable between a position in which the retention element is prevented from moving to release the plunger, and a position in which the retention member moves freely. The outer sleeve includes a trigger wall portion which may be depressed to move the retention element once the retention element is free to move, releasing the plunger.

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

Abstract: A drug delivery system is provided including a drug expelling structure adapted to expel a set dose from a drug-filled cartridge, the expelling structure including a rotational member adapted to rotate relative to a housing and corresponding to a set and/or expelled dose, the system including a sensor adapted to detect a set and/or an expelled dose. The sensor includes a first portion mounted to and rotating with the rotational member, and a second portion including a second rotary sensor part mounted non-rotationally relative to the housing. The first portion includes electronic circuitry, and a first rotary sensor part, and the second portion includes a second rotary sensor part mounted non-rotationally relative to the housing. The first and second rotary sensor parts rotate relative to each other during setting and/or expelling of a dose of drug.

Abstract: A device introduced small volumes of fluid for delivery to a patient through a fluid line. The device includes a first arm adapted to receive a syringe and a second arm fluidly connected to an upstream reservoir that defines an internal volume adapted to receive a volume of fluid. The device includes a fluid obstruction mechanism configured to selectably block flow of fluid from the reservoir toward the patient, wherein the fluid obstruction mechanism transitions between a first state that permits fluid flow from the reservoir toward the patient and a second state that directs fluid flow from the syringe into the reservoir while blocking fluid flow from the reservoir toward the patient.

Abstract: Certain exemplary embodiments comprise can comprise an auto-injector, which can comprise: a vial configured to store and/or contain an injectable medicament, the vial defining a vial longitudinal axis, and a housing comprising the vial. In various embodiments, the injectable medicament can be a medicine, medication, drug, pharmaceutical, prescriptive, agent, antidote, anti-venom, hormone, stimulant, vasodilator, anesthetic, and/or nutritional supplement that is substantially ready for injection.

Abstract: Various handheld medical dispensing configurations and methods including the following. Handheld medical dispensing system comprises a syringe, which has a plunger, releasably mounted to syringe actuation apparatus, the apparatus having an actuator configured such that it can move the plunger more than once to dispense a plurality of amounts of substance from the syringe. A method of dispensing fluid from a syringe comprises holding a medical substance delivery system including a syringe, which has a needle, and which is secured to syringe actuation apparatus configured to dispense predetermined amounts of the substance from the syringe, penetrating the needle at one patient site and using the apparatus to deliver a predetermined amount of the substance, and penetrating the needle at another patient site and using the apparatus to deliver a predetermined amount of the substance.

Abstract: The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

Abstract: The present invention relates to a variable metered amount airless applicator with cartridge. Examples of such an applicator include, for example, syringes and gun-shaped applicators. A variable amount selector is a feature of an embodiment of the applicator. The applicator can be attached to a variety of pass-through devices.

Abstract: An injection device (210) is described. A housing (212) receives a syringe and includes a return spring (226) for biasing the syringe from an extended position in which its needle (218) extends from the housing (212) to a retracted position in which the it does not. A drive spring (230) acts on a first drive element (232) and a second drive element (234) acts upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the needle. The first drive element (232) is capable of movement relative to the second (234) once a nominal decoupling position has been reached. A release mechanism is activated when the first drive element (234) is further advanced to a nominal release position, to release the syringe (214) from the action of the drive spring (230), whereupon the return spring (226) restores the syringe (214) to its retracted position.

Abstract: The present invention concerns an injection device with a housing adapted to receive a syringe having a discharge nozzle, the housing having an indicator opening. There is a trigger and a forward drive arranged to act upon the syringe on actuation of the trigger to advance the syringe from a retracted position to an extended position thereby discharging the contents of the syringe through the discharge nozzle. A support member is in contacting juxtaposition with the housing and a return drive is supported by the support member and arranged to act upon the syringe after the contents of the syringe has been discharged so that the syringe can be withdrawn from the extended position to the retracted position. Advantageously, the support member is arranged in the housing so that the second drive does not obscure an inspection of the contents of the syringe through the indicator opening. Hence, it can be clearly determined whether the contents of the syringe have been expelled from the syringe.

Abstract: The invention relates to injection device, which device comprises an outer housing (1), a syringe body (10) and a needle shield (30). Both the syringe body (10) and the needle shield (30) are telescopically movable mounted to the housing (1) such that the needle shield (30) is movable relatively to the housing (1) between a first position and a second position, and the syringe body (10) is movable in relation to the housing (1) between an extended position and a retracted position.

Abstract: An infusion system for delivery of therapeutic fluids from a remote source into a patient's body. The system has an infusion assembly, a rotating pivot joint member, a fluid connector assembly, and a sealing assembly retained within the infusion assembly between the housing of the infusion assembly and the rotating pivot joint member. The seal reduces leakage of fluids. The rotating joint may be pivoted to three distinct positions to allow for emplacement on the patient, delivery of the therapeutic fluid to the patient, and protected, sealed closure of the fluid channels to avoid patient fluid backflow.

Abstract: An auto-injector for injecting a fluid medicament into a patient from a pre-filled syringe requires a disposable cassette that is selectively engageable with the reusable injector. The syringe is latched onto the cassette, and the cassette is then engaged with the injector. Activation of the injector causes a first motor to move the syringe so its needle is extended from a concealed position inside the cassette for injection of the medicament. A second motor on the injector is then activated to expel fluid medicament from the syringe. Then, the first motor is again activated to withdraw the syringe into the cassette for disposal of the cassette/syringe after an injection.

Abstract: The present invention relates to a dose setting mechanism for a drug delivery device and a method of using same. The mechanism comprises a drug delivery device housing, a dose dial component positioned in the housing and rotatable during dose setting and dose delivery, a clutch rotatable during dose setting and non-rotatable during dose delivery having, preferably located at a distal end, clutch teeth, and a clutch ring engaged with the housing in a first rotatable configuration and in a second non-rotatable configuration.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate case arranged to be held by a user, a tubular chassis telescopable in the case and biased against the case so as to protrude from the case, a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, a trigger button which is initially abutted against the case thus preventing actuation, wherein the chassis is arranged to translate into the case against the bias when pressed against an injection site, wherein the trigger button is at least initially coupled to the chassis in such a manner that the trigger button emerges from the case when the chassis is being pressed against the injection site so as to allow actuation by being translated towards the case for starting an injection cycle.

Abstract: A piston rod for a drug delivery device comprises a main body and an engagement means for engaging the piston rod with a part of the drug delivery device. The engagement means are retractable relatively the main body for enabling a disengagement of the engagement means from the part of the drug delivery device.

Abstract: The present invention relates to an injection device for automatic torsion spring driven injection of a liquid drug. The injection device is of the type wherein a telescopically movable needle shield (20) activates the release of the torque of the torsion spring to drive the injection when the needle shield is moved from its extended position to a retracted position. The injection device is provided with a needle interface (30) carrying the injection needle, which needle interface is provided with means (32) preventing axial movement of the shield when no injection needle is mounted. Further, other means are provided to restrain the needle shield in the retracted position when the injection device is its “zero” position such that a user has access to the injection needle in order to exchange the injection needle.

Abstract: A method of decoding encoded information is presented where one or more sensors are controlled to periodically check for motion of a movable component of a drug delivery device having encoded information thereon. If motion of the movable component is detected, preventing a first encoded information reading and decoding process from being performed, when motion of the movable component is not detected, performing the first encoded information reading and decoding process.

Abstract: A device for delivering medication is presented. The device has a conduit with an upstream end and a downstream end. The downstream end of the conduit delivers the medication. The device has a housing with an open end and an end forming a flat substrate. The housing receives a vial containing a liquid and having a stopper. The device also has a valve for releasing the liquid from the vial into the conduit. The valve can be opened and closed by a user of the device. To release the liquid a piston is utilized to exert pressure on the stopper of the vial and the liquid is dispensed through a needle into the conduit.

Abstract: The invention relates to an injection device including an injector and an ampoule unit for the needle-free injection of a medium. A needle-free injection device has a first chamber with an interior that opens into a nozzle, and has a second chamber with an interior that is separated from the interior of the first chamber. The interiors of the two chambers are connectable to each other, thus allowing a mixing and/or reaction of the media located in the chambers. In the first chamber, a powdery medium can be accommodated, and in the second chamber, a fluid medium is can be accommodated. The fluid medium can be transported into the first chamber for the mixing/reaction of the two media.

Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.

Abstract: An infusion pump assembly is disclosed. The infusion pump assembly includes a locking tab and a pump barrel inside a pump barrel housing, where the pump barrel accommodates a reservoir assembly. The reservoir assembly includes a reservoir and a plunger rod. The infusion pump assembly also includes a locking disc at a terminus of the pump barrel. The locking disc includes a clearance hole for the plunger rod. The locking disc also includes at least one locking tab notch in close proximity with the locking tab. The locking tab is in moveable engagement with the locking tab notch, and the reservoir moves the locking tab from a locked position to an unlocked position when the plunger rod is inserted through clearance hole. The locking disc rotates upon torque being applied to the reservoir assembly, the locking disc rotating from a non-loaded position to a loaded position with respect to the plunger rod and a drive screw.

Abstract: An arrangement for coupling a plunger to either a syringe or a stopper arranged in the syringe. The arrangement includes a syringe holder which is slidably arranged in a housing. The syringe holder is provided with at least one resilient syringe holder arm arranged distally, the syringe holder arm having an inclined surface for bearing against a shoulder, which is arranged at the plunger. The syringe holder arm is supportable by an inner surface of the housing in order to prevent it from being flexed outward in a first position. A widened portion is provided in the housing for allowing the syringe holder arm to flex outwards and disconnect from the plunger when in a more proximal position so as to switch load of the plunger from the syringe to the stopper.

Abstract: An exemplary embodiment of the present disclosure can provide an injector including a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

Abstract: A drug delivery device includes a cartridge (211) for storing a medicament and a needle (203) communicating with the cartridge (211) for injecting a medicament dose. A rack (241) is movably disposed in the cartridge (211) and is engageable with a stopper (213) for expelling the medicament dose from the cartridge (211). A lever assembly (231) has a lever arm (233) connected to a lever gear (230). The lever gear (232) is engaged with the rack (241) such that rotation of the lever arm (233) rotates the lever gear (232) during injection of the medicament dose, thereby moving the rack (241) and stopper (213) through the cartridge (211) to deliver the medicament dose.

Abstract: One variation of a dynamic tactile interface includes a tactile layer defining a peripheral region and a deformable region adjacent the peripheral region; a substrate coupled to the peripheral region, a fluid conduit adjacent the deformable region, a fluid channel fluidly coupled to the fluid conduit, and a via fluidly coupled to the fluid channel and passing through the back surface; a bladder fluidly coupled to the via and the substrate; a structure adjacent a first side of the bladder; and a platen adjacent a second side of the bladder opposite the first side and compressing the bladder against the structure substantially perpendicular the longitudinal axis of the bladder and substantially parallel the substrate to displace fluid from the bladder and into the fluid channel to transition the deformable region from a retracted setting into an expanded setting.

Abstract: A cylinder-piston unit, with at least one cylinder accommodating an injection solution, at least one piston, and an adhesive coating arranged in the area of the free end face of the cylinder. The cylinder has a bottom portion, on which a discharge tube is arranged. An adhesive disc, which is displaceable in the direction of the center line of the cylinder-piston unit between an installation position and an application position, is arranged on the discharge tube and/or on the bottom portion. On its end face directed away from the bottom portion, the adhesive disc has an adhesive coating. In the storage position, the adhesive disc has at least one sealing element or a sealing area for closing the discharge tube, the effect of which sealing element or sealing area is no longer present in the application position.

Abstract: An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.

Abstract: The subject invention provides a drug delivery device for injecting medicament which includes: a tubular reservoir; a stopper slidably disposed in the reservoir; a spring for moving the stopper in the reservoir; at least one needle, the needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, the lumen being in direct or indirect communication with the reservoir; a needle driver for displacing the needle; and, an actuator. Activation of the actuator causes the spring to move the stopper and the needle driver to displace the needle. The needle moves relative to, and separately from, the reservoir with the needle being displaced. Advantageously, with the subject invention, a drug delivery device is provided wherein a needle is moved, relative to the reservoir, in being displaced for injection. This permits control of the needle displacement separate from the reservoir.

Abstract: Automatic injection device includes a housing, a syringe, a plunger, and a syringe carrier. The housing includes a barrel. The barrel includes an elongated window to allow viewing of contents inside the housing. The syringe is disposed within the housing and has a reservoir. The plunger is at least partially disposed within the syringe and includes a visual indicator. The syringe carrier is disposed within the housing and configured to contain the syringe and displace the syringe within the housing between a first position and a second position. The syringe carrier has a first opening and a second opening. The first opening is configured to align with the window and the reservoir when the syringe carrier is in the first position, and the second opening is configured to align with the window and the visual indicator when the syringe carrier is in the second position.

Abstract: The invention relates to a device for inserting needles, including a body defined by a proximal end and a distal end, a mounting movably mounted inside the body, at least one needle secured to the mounting, a drive means suitable for driving the mounting towards said distal end, said mounting comprising a distal surface onto which the needle projects, said distal end comprising a contact area intended for contacting the tissue, the mounting being configured so as to reach a position, after activating the driving means, in which the distal surface thereof, relative to said proximal end, is more distant than said contact area, wherein the device is further configured so as to enable a gradual passive return movement of the mounting once said position has been reached.

Abstract: A drive assembly for a medication delivery device is provided, comprising a piston rod which is movable from a start position to an end position for medication delivery and resettable from the end position to the start position. The drive assembly further comprises a guide member, being in engagement with the piston rod, and an impeding element for impeding a movement of the guide member during a reset of the piston rod and thereby impeding the reset of the piston rod. Furthermore, a medication delivery device comprising the drive assembly is disclosed.

Abstract: The dynamic tactile interface includes: a tactile layer defining a peripheral region and a deformable region adjacent the peripheral region and operable between a retracted setting and an expanded setting; a substrate including an attachment surface and coupled to the peripheral region and defining a fluid conduit adjacent the deformable region and a fluid channel fluidly coupled to the fluid conduit; a border region proximal a periphery of the substrate and defining a cavity configured to receive an instrument, the cavity supporting the instrument in a first configuration and releasing the instrument in a second configuration; and a bladder fluidly coupled to the fluid channel and coupled to the cavity, the instrument compressing a portion of the bladder in the first configuration to displace fluid from the bladder into the fluid channel to transition the deformable region from the retracted setting to the expanded setting.

Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.

Abstract: An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

Abstract: An exemplary embodiment of injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

Abstract: Describe is an auto-injector comprising a syringe carrier arranged to retain a syringe, a plunger arranged to displace a stopper within the syringe, a feedback component retainable in a first position and biased towards a second position, a pin disposed on the feedback component, and an exterior component having a bore. The feedback component moves from the first position to the second position when the plunger during displacement of the stopper reaches a predetermined position. The pin enters the bore when the feedback component is in the second position.

Abstract: A method of treating diseased ethmoid sinuses in a patient with a therapeutic agent includes providing an injection device comprising an elongate member having a proximal end, a distal tip or end, and a lumen extending between the distal tip or end and the proximal end, the proximal end being operatively coupled to a source of the therapeutic agent. The distal tip or end of the injection device is inserted at least partially within an interior portion of an ethmoid air cell. The therapeutic agent is then injected into the interior portion of the ethmoid air cell using the injection device, the therapeutic agent being delivered via the lumen in the elongate member.

Abstract: A portable medicament dispensing device having a mechanism which is not susceptible to jamming for dispensing the medication to a user. The device employs employs a coupling for coupling the relative motion between reciprocating body members housing the ancillary components and a barrel plunger associated with the syringe. One embodiment provides a pivoting coupling whereas an alternate uses a rack and pinion system. The advantage of simplifying such mechanisms results in a structure which has smooth unemcumbered motion with fewer parts to avoid mechanical jamming during use.

Abstract: A safety needle is provided. The safety needle includes a substantially hollow body and a needle assembly that includes a needle supported on a needle hub. The needle hub is movable in relation to the hollow body from an advanced position wherein a sharp tip of the needle extends from the hollow body to a retracted position wherein the sharp tip of the needle is positioned within the hollow body. The safety needle also includes a spring biased retraction mechanism that includes a constant force spring operatively connected to the needle hub. The constant force spring is a generally flat strip of prestressed material that is formed into constant coils around itself. The constant force spring is configured to bias the needle hub towards the retracted position wherein the spring provides a substantially constant force to the needle assembly while the needle assembly moves from the advanced position to the retracted position.

Abstract: A medicament delivery device has an elongated housing; a medicament container carrier for a medicament container to which a medicament delivery member is attached, the carrier being slidable in the housing; a trigger unit; a cover unit coaxial and slidable in the housing; a release mechanism adapted to be actuated partly by the trigger unit and partly by movement of the cover unit; a preloaded drive unit releasably connected to the carrier and controlled by the release mechanism for advancing the carrier to a predetermined proximal position in relation to the housing at which the drive unit becomes disconnected from the carrier for advancing a slidable stopper in the container and thereby dispensing the medicament; and a braking mechanism acting between the preloaded drive unit and the release mechanism for controlling the speed of the preloaded drive unit when advancing the slidable stopper in the container.

Abstract: An automatic injection device (100) adapted to automatically eject a dose of a medicament by automatically inserting a needle (112) into the skin of a user, ejecting a dose of a medicament through the needle, and subsequently retracting the needle into a housing (122) of the device.

Abstract: A medical instrument includes a handpiece, a tank portion for housing a fluid, a plunger that changes a volume or pressure of an inside of the tank portion to suction the fluid into the tank portion or discharge the fluid from the tank portion, and an operating unit for operating the plunger. The handpiece includes a grip portion at the front end, and an operation member of the operating unit is disposed on a side of the grip portion.

Abstract: The present invention relates to a medicament delivery device (10) comprising a housing (12, 14); a medicament container (22) arranged inside the housing; a medicament delivery drive unit comprising a plunger rod (28) acting on said medicament container (22) and a power force (26) capable of driving said plunger rod (28) for delivering a dose of medicament. The invention is characterised in a delivery controller (30) comprising a manually operable release mechanism (30, 36) for releasing said plunger rod (28) and said power source (26) for delivering a dose of medicament and a manually operable control speed mechanism (30, 38) capable of controlling the speed of the released plunger rod and thereby the medicament delivery speed.

Abstract: An injection device for use with a syringe having a syringe body, a needle coupled thereto, and a plunger moveable through the body to eject medication from the syringe through the needle, includes a housing defining an inner space for holding a syringe and facilitating movement thereof from a first position in which the needle is contained fully within the housing and a second position in which the needle projects from the housing, and a drive member located within the inner space so that in use the drive member can engage the plunger of a syringe held within the housing. The device further includes a force applicator located within the inner space for providing a force to the drive member so as to move the syringe from the first to the second position and thereafter to move the plunger through the syringe body, a trigger mechanism, and a damper.

Abstract: A medicament delivery device includes a body having a proximal end and a distal end, in turn comprising a distal housing part, and a medicament container holder, adapted to receive a medicament container; a dose setting drum for setting a dose when rotated in a first direction and for delivering a dose when rotated in a second direction, and a drive drum sleeve selectively operably connectable to a piston plunger for delivering a dose.

Abstract: Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the catheter are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.

Abstract: An auto-injector for delivering a liquid medicament (M) is presented having an elongate housing having a loading bay configured to receive a packaged syringe, wherein the loading bay is configured to be laterally accessible for inserting or removing the packaged syringe, wherein a sliding door is slidably arranged over the housing in a manner to reveal the loading bay in a distal position and to cover the loading bay in a proximal position.

Abstract: An apparatus includes a housing, a needle, a first energy storage member and a second energy storage member. The needle is movably disposed within the housing and is configured to be to be placed in fluid communication with a medicament container. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The first energy storage member is disposed within the housing, and is configured to produce a first force when actuated. The second energy storage member is disposed within the housing, and is configured to be actuated in response to the first force to produce a second force to move the needle from the first needle position to the second needle position.