Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates to an infusion device comprising a housing (10, 12); a compartment inside said housing for positioning a medicament container (78), an infusion needle (124) arranged to said housing, being connectable to said medicament container for delivering a dose of medicament, a piston plunger (72) arranged in said housing capable of acting on said medicament container for delivering a dose of medicament, mechanical drive means capable of acting on said piston plunger for delivering a dose of medicament. The invention is characterised in that said piston plunger comprises a number of distinct segments (82) being inter-connectable to each other for forming an elongated piston plunger.

Abstract: The invention relates to an injection device comprising a housing, a container holder arranged within said housing, the container holder being configured for accommodating a medicament container having a needle attached to one end thereof and a stopper sealingly and slidable arranged inside the medicament container at the other end thereof, a plunger rod being arranged with a proximal end thereof contactable with said stopper, a first and a second energy accumulating member arranged in the interior of the housing of the injection device and adapted to accumulate and store energy, plunger drive means being slidable arranged in relation to the plunger rod, being rotationally locked to the plunger rod and being rotatable in relation to the housing, the plunger drive means being operationally associated with the first energy accumulating member, a container driver arranged for being connectable to the container holder and threadedly connected to the plunger rod, the container driver being operationally associated

Abstract: Injection systems comprising a powered injector and one or more hazardous agents are disclosed.

Abstract: An injection device comprises a syringe extendible against a spring bias from a retracted position in a housing to a projecting injecting position. A spring biased plunger has collapsible elbows which, when the plunger is released, initially engage the end of the syringe to drive it to the projecting position, whereupon arresting of the syringe movement causes the elbows to collapse inside the syringe to allow the plunger to engage and drive the bung.

Abstract: A medicament delivery device includes a housing; a drive force mechanism slidable in the housing's distal part; a member connected to the drive force mechanism for holding it in a loaded state and axially movable in relation to the distal part a predetermined distance by the housing's proximal part when the parts are moved toward each other; and an actuation member to be biased in relation to the distal part from a non-operating position partially protruding from the distal part to an operating position confined within the distal part. The actuation member can release the drive force mechanism from its loaded state, and is resiliently connected to the distal part such that it is always recoiled after being biased regardless of whether the actuation mechanism is released. The drive force mechanism is released only after the holding member moves and the actuation member is biased from non-operating to operating position.

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: An infusion pump unit includes a housing sized to allow the pump unit to be carried as a portable unit. The housing contains a controllable pumping system for pumping fluid. The pump actuator is lighter, smaller, quieter and less power consuming.

Abstract: A pump apparatus that exerts a constant force on a bag of fluid to provide a uniform flow rate compared to elastomeric pumps. The apparatus comprises a first and a second block member positioned over a plate, which are moveable to define an opening to receive a wedge member attached on the plate. The block members are coupled by a resilient means that is extendable when the wedge member is urged into the opening. The extended resilient means is retractable such that the plate exerts a constant force on the bag to expel fluid in a uniform flow rate.

Abstract: Electronic pill (1, 11, 21) comprising a plurality of medicine reservoirs (2, 12, 22), each of the reservoirs comprising a discharge opening (3, 13, 23) covered by a removable cover (6, 16, 26). The pill comprises at least one actuator responsive to control circuitry for removing the cover from the discharge opening (3, 13, 23). The actuator can for example be a spring loaded piston (4) breaking a foil cover when dispensing the medicament. 5 Alternatively, the cover can be a rotatable disk (16) or cylinder (26) with an opening (17, 27) which can be brought in line with the discharge opening of a reservoir under the action of the actuator.

Abstract: A two-dose autoinjector for a medicament wherein the locking and releasing of the drive spring of the autoinjector is controlled through stepped guides with ramps for two successive slidings of slides operated by the spring and connected with the syringe and plunger. The guides and the slides are pivotable relative to one another and the sliding direction, while the syringe can only slide axially. To enable or disable the sliding of the slides within the guides an angularly angularly mobile arming member is provided formed with a guide track substantially equal to that of the stationary member where the guides are formed.

Abstract: A mechanical driver comprising a wedge shaped member operatively coupled to a shape memory alloy such that the shape memory alloy is able to displace the wedge shaped member in an essentially linear direction. The wedge shaped member is in constant contact with a lever arranged so that it can rotate about a fixed pivot point. A piston is arranged such that it is constant contact with the lever at a point between the pivot point of the lever and the contact point between the lever and the wedge shaped member. Return springs are provided to return the piston, lever and wedge shaped member to their respective start positions. Activation of the shape memory alloy displaces the wedge shaped member along its linear direction and this causes the lever to be deflected about its pivot point and the piston to be deflected in an essentially linear direction that is perpendicular to the linear direction of travel of the wedge shaped member.

Abstract: A disposable auto injector (10) having a housing for accommodation of a syringe (18) with a needle movably positioned in the housing between a first position in which the needle is inside the housing and a second position in which the needle protrudes outside the housing, a driver (22) positioned laterally in relation to the syringe and configured for applying a force to the syringe thereby moving the syringe from the first position to the second position, a first injection lock configured in a locked state for preventing syringe movement from the first position to the second position and an injection trigger member (16) configured for releasing the first injection lock to an unlocked state wherein the first injection lock comprises a rotatable release shaft (34) configured for rotation between a first angular position in which it prevents movement of the syringe from the first position to the second position and a second angular position in which position does not prevent movement of the syringe from the fir

Abstract: A drive mechanism having integrated status indication includes a drive housing, a status switch interconnect, a drive biasing member, a piston, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the drive biasing member is configured to bear upon an interface surface of the piston. Drive mechanism may include an incremental status stem having a stem interconnect, wherein the stem resides within the drive housing and the piston, and wherein the stem has an interconnect which engages one or more contacts on the piston to provide incremental feedback. A drug delivery pump with integrated status indication includes a housing and an assembly platform, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection, a power and control system, and the drive mechanism having a drug container may be mounted.

Abstract: A disposable syringe assembly for use in an autoinjector device, or manually includes a syringe housing which receives the syringe barrel and which is restrained against longitudinal movement with respect thereto, a shield portion mounted for generally telescopic movement relative to the syringe housing between a retracted position and an extended position in which in use it shields the syringe needle, and a lock out arrangement activated as the shield moves towards its extended position to prevent retraction therefrom. When fitted in an autoinjector the autoinjector may include drive mechanism for moving the shield portion to its locked out extended position, whereby, on completion of an injection operation, the disposable syringe assembly may be removed from the autoinjector in a shielded condition for subsequent disposal.

Abstract: An autoinjection device includes a main body 12 in the front end of which is slideably mounted a drawer or front body portion 14. The drawer can be opened to remove or insert a syringe. Closing the drawer while pressing a multifunction button 22 primes the drive mechanism 54, 58 by latching it against trigger latch 66. Pressing the button 22 again while urging the front end causes the drawer to release the trigger latch 66. After the injection the drawer shrouds the used needle and can be released only by pressing the button 22.

Abstract: An injection device for injecting injection material, comprising: an elastic deformable element (3) able to exert a pushing force on a piston (20) of a syringe (2) so as to eject a quantity of injection material out of the syringe (2); a stopper (4) for retaining the extension of said spring (3) when the stopper is in a first position (A) and for releasing the extension of said elastic deformable element when the stopper is in a second position (B); an electric actuator (5) for moving the stopper (4) from its first position to its second position or from its second position to its first position.

Abstract: An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration.

Abstract: The filling status of a drug reservoir in a drug pump devices may be determined with mechanical and/or magnetic position sensor associated with a reservoir boundary.

Abstract: A spring force assembly for biasing a displaceable stopper of a liquid medicament cartridge including a spring element arranged along a longitudinal axis, with brace elements and coupling elements, with the coupling elements restricting the distance between the brace elements which also restricts the possible expansion of the spring element.

Abstract: A pen-type injector for receiving a medication containing member. The injector comprises a housing 1 and a torsion spring 4 contained within the housing and coupled to a drive member 8. A dose setting knob 2 is coupled to the spring 4, and rotatably coupled to the housing 1 such that rotation of the knob relative to the housing in a first direction results in compression or twisting of the spring. A user actuable trigger 12 is provided for releasing the spring 4 to push the drive member 8 through the housing 1. A user actuable button 6 is coupled to the housing 1 for axial motion relative thereto, said button 6 being coupled to the torsion spring 4 to cause the spring to unwind or expand in discrete steps with each press of the button.

Abstract: The present invention provides for an autoinjector that registers off a distal end of a syringe to provide for a more accurate needle insertion depth. The autoinjector employs an automatically deployable frontal buttress for registration of the distal end or shoulder of the syringe.

Abstract: Described is an injection device for administering a dose of a medicament (M) comprising a carrier adapted to contain a syringe having a hollow injection needle and a stopper, a drive spring, a plunger adapted to forward load of the drive spring to the stopper, and a noise component adapted to generate an audible and/or tactile feedback by impacting a component of the injection device when the stopper is located at a proximal end of the syringe. In a first state, a resilient arm on the plunger is maintained in engagement with the noise component by the carrier. In a second state, the arm disengages the noise component and deflects at least partially into an aperture in the carrier.

Abstract: The ear irrigation device for the removal of earwax integrates a fluid injector assembly with a fluid container (2) which is loaded and discharged by means of a guided rod (3) and plunger (4) assembly with bidirectional linear sliding through its inside, arranged in the container (2), which it divides into a front chamber (2a) and a rear chamber (2b), an actuating element (5) to move the rod-plunger assembly (3, 4) to said retracted position, a retaining element (13) to retain it, and a nozzle portion (6) for discharging by ejection the fluid of the front chamber (2a) of the container (2) having been provided. A handgrip (7) with a trigger (8) controls the retaining element (13) to release the rod-plunger assembly (3, 4) and allow it to move towards said extended position. The rod (3) of the plunger (4) is hollow and houses a fixed axial guide element (10) and a spring (12) coaxial to the axial element (10).

Abstract: A medicament delivery device includes a housing with a circle-segment-shaped compartment for a drive unit that moves at least one stopper in a medicament container and that includes a support wheel and central hub on which first and second parallel disks are fixedly attached and interconnected by an abutment cross-wall; spherical members between the abutment wall and adjacent the stopper; a clock spring within the hub with an outer end connected to the hub and an inner end connected to a one-direction-rotatable tubular hub coaxially arranged around a shaft fixedly attached to a housing part; and an activation member connected to the first disk by a hold-and-release mechanism. When the activation member is not depressed, the wheel and spring are held in a tensioned static state, and when the activation member is depressed, the spring and wheel are released and the spherical members are forced against the stopper.

Abstract: The present invention relates to a disposable auto injector that can be safely operated for automatic injection of a dose of medication and having a housing for accommodation of a syringe with a needle, the syringe being movably positioned in the housing between a first position in which position the needle is accommodated inside the housing and a second position in which position the needle protrudes outside the housing, a mechanical driver anchored to the housing at a first anchor location for applying a force to the syringe thereby moving the syringe from the first position to the second position, and wherein the mechanical driver is also configured for applying a force to the syringe by anchoring the mechanical driver to a different second anchor location.

Abstract: A dose reset mechanism for a medicament delivery device with a housing and a medicament container includes a dose setting member in the housing for setting a dose when it is rotated and for resetting the dose when it is rotated in the opposite direction. The dose setting member has a drive member connected to a plunger rod such that when the drive member rotates, the rod moves axially; and a connection member between the dose setting member and the drive member. A ratchet mechanism enables the connection member to rotate when the dose setting member rotates for setting a dose but not to move in the opposite direction. At least one dose reset member and at least one blocking member are connected to the ratchet mechanism such that the connection member and drive member are released when a dose knob is turned in the opposite direction.

Abstract: An automatic syringe pump is disclosed that includes at least four subsystems: mechanical power, electronic timing, mechanical power transfer, and user interface subsystems. In some embodiments, an occlusion detection subsystem is also present. The mechanical power subsystem's main includes a constant force spring capable of storing the energy needed to reliable depressed several different sizes of a syringe. The electronic timing subsystem may include components including a ratchet, pawls, flippers, stepper motor, and microcontroller. These components are used together to regulated the release of the energy stored in the constant force spring. The mechanical power transfer subsystem may include components including a rack and pinion which translates the rotational motion of the drive shaft from the constant force spring into linear motion to depress the syringe. Finally, the user interface subsystem may include components including the microcontroller, Arduino backpack, and syringe tray.

Abstract: An adapter for use with an appliance for administering an injectable product, the adapter serving to create a product connection between a catheter and a product container that can be inserted into the appliance, and including a thread for screwing the adapter to the appliance, a stop for fixing the container in the longitudinal direction of the thread, an attachment piece to which the catheter may be connected, and a product channel that extends through the attachment piece and the thread.

Abstract: Embodiments of the invention include a medicament device configured to provide stepwise instructions for using the device to a user in a particular sequence is provided. The device includes a reusable housing configured to receive a container, the reusable housing including a control interface, the control interface including at least one responsive member reactive to a user input, an actuation member configured to interact with the container, a signal output component associated with the reusable housing; and circuitry associated with the reusable housing configured to control a provision of the stepwise instructions to the user in the particular sequence.

Abstract: A reloadable auto injector for epinephrine injection is provided. A syringe driver applies a force to the syringe to move the syringe together with plunger rod tube, plunger rod and plunger rod driver from the first position to the second position. In the second position, the locking member is unlocked and releases the plunger rod to thereby activate the plunger rod driver to advance the plunger rod in the syringe for delivering of medicament. A reload handle is connected to the syringe assembly so that user operation of the reload handle retracts the syringe to the first position and simultaneously reload the syringe driver to thereby ready the auto injector for delivering a further dose of medicament.

Abstract: The invention relates to a device (1) for automatic injection of a product into an injection site, said device (1) further comprising a needle (6) and a needle shield (2) for protection of said needle (6) prior to use of said device, and a housing (300) receiving the container (50) and a deshielder (8) for removing said needle shield (2) from said device (1), said deshielder (8) being coupled to said needle shield (2) and being mounted on the housing (300) in a separable manner, for example through breakable or snap-fit means, said deshielder (8) comprising tamper evidence means that are activated by the removal of at least one part of said deshielder (8). Said at least one part of said deshielder (8) can be removed from the housing (300) by exerting a traction force equal or less to 30 N.

Abstract: The invention provides an accessory (10) for a Loss of Resistance Syringe (20), the accessory comprising a coiled spring (12) attachable to the exterior of the syringe for biasing the plunger (22) towards the barrel (24) of the syringe. When the plunger of the syringe is withdrawn, the spring is subjected to a compressive force against which it will act. In use, as the syringe enters the epidural space, a loss of resistance will allow the spring to pull the plunger back towards the barrel of the syringe, and alerting the user not to push the needle any further.

Abstract: An automatic injection apparatus including a delay mechanism for properly delivering medication prior to the needled syringe of the apparatus being retracted. In one form, the delay mechanism includes a shuttle for the syringe, a follower, a locking member, a damping compound between the follower and a supporting surface to dampen rotation of the follower relative to the shuttle, and a dual functioning biasing member acting between the shuttle and the follower. When the locking member moves to a release position during an injection, the dual functioning biasing member first provides a torsional force to force the follower to rotate relative to the shuttle from a latching position to an unlatching position, and then the dual functioning biasing member provides an axial force to force the shuttle axially relative to the follower to move the shuttle for retracting the syringe needle into the housing of the apparatus after injection.

Abstract: An actuation mechanism for an automatic injector includes a first actuation spring, a first actuation pill, a second actuation spring, and a second actuation pill. In an initial configuration the first actuation spring resides in a compressed, energized state substantially within an upper portion of first actuation pill and the second actuation spring resides in a compressed, energized state between the first actuation pill and the second actuation pill. An automatic injector includes a housing, an activation mechanism, an actuation mechanism, and a syringe cartridge having a plunger and a needle assembly. A retractable syringe may be utilized as a syringe cartridge, such as a prefilled retractable syringe with integrated safety features which retract the needle after use. The automatic injector may be utilized to inject the needle, deliver a drug treatment, and activate retraction of the needle. Methods of assembly and operation are also provided.

Abstract: The present invention provides a disposable trumpet valve tube cassette assembly, as well as, a surgical irrigation instrument that includes a probe assembly, a pump, a removable pump cartridge, and a socket. The probe assembly provides passage of fluids for irrigating the body interior and for evacuating matter from the body interior. The pump provides for pumping irrigation fluid through the probe assembly into the body interior. A pump cartridge defines a pumping chamber. Electronic control circuitry includes an electronics controller and a trumpet valve switch interface. The electronics controller includes a pulse generator that generates pulses, the duty cycle of the pulses controlling the speed of the motor. The trumpet valve switch interface is in electronic connection to a switch, the interface providing a signal to the controller.

Abstract: A method for providing a substantially painless injection of medication into a patient, including inserting an injection needle having an outside diameter greater than 0.20 mm and less than about 0.38 mm, and injecting a medicament through the needle and into the patient at a substantially constant volumetric flow rate of about 0.05 ?L/s to about 50 ?L/s that provides a painless injection. The method does not require the use of an anesthetic or that the medical personnel to spend a substantial amount of time performing the injection procedure, is relatively simple and inexpensive to perform and operate, and provides a relatively high degree of safety for both the medical personnel and for the patient.

Abstract: Exemplary embodiments provide firing mechanism assemblies that minimize or eliminate a misfire of an automatic injection device that causes a delay in the delivery of an injection. Exemplary embodiments provide automatic injection devices including firing mechanism assemblies that minimize or eliminate a misfire that causes a delay in the delivery of an injection. Exemplary embodiments provide methods for minimizing or eliminating misfire that causes a delay in delivery of an injection in automatic injection devices. Exemplary embodiments provide methods for using automatic injection devices that are free of a misfire that causes delay in delivery of a therapeutic substance into a patient's body.

Abstract: A one-time use device to deliver preservative-free follicle stimulating hormone (FSH) solution is disclosed. The device includes a needle covered by a sliding needle shield, which covers the needle in all modes of the device. The device can be placed into a ready-to-use position in four or fewer user steps. The device has a knob for setting a desired dose of FSH. The knob includes longitudinally spaced elements respectively corresponding to the lock position and the seven or fewer discrete dosing positions. The device locks after one use and cannot be reused thereafter.

Abstract: An automatic injection apparatus including a delay mechanism for properly delivering medication prior to the needled syringe of the apparatus being retracted. In one form, the delay mechanism includes a shuttle (170) for the syringe, a follower (250), a locking member, a damping compound between the follower and a supporting surface (308) to dampen rotation of the follower relative to the shuttle, and a dual functioning biasing member (290) acting between the shuttle and the follower. When the locking member moves to a release position during an injection, the dual functioning biasing member first provides a torsional force to force the follower to rotate relative to the shuttle from a latching position to an unlatching position, and then the dual functioning biasing member provides an axial force to force the shuttle axially relative to the follower to move the shuttle for retracting the syringe needle into the housing of the apparatus after injection.

Abstract: The invention relates to an intraruminal sustained release capsule which is capable of delivering a sustained release dose of a first medicament to an animal, as well as either or both of a dump dose of a second medicament or mineral, and an exit dose of a third medicament or mineral. The capsule can have a dissolvable overcap molded from plasticized starch enabling a dump dose of medicament to be held between the overcap and one end of the capsule. A piston within the body of the capsule can be modified to enable it to accommodate an exit dose of medicament within its hollow interior which is aligned with an aperture at the end of the capsule which enables release of the medicaments to the rumen. After insertion of the capsule in the animal the overcap (if present) dissolves and separates from the capsule to release the dump dose of medicament. The sustained release medicament is then dispensed via the apertured end, followed by the release of the exit dose of medicament (if present).

Abstract: An injection device comprising an outer housing adapted to receive a syringe for holding a volume of a medicament, said syringe comprising a barrel, a needle at one end of the barrel, and a plunger, axially moveable within the barrel, the needle and barrel being such that at least part of the needle is axially moveable in and out of said outer housing but is biased to be normally wholly inside said housing. The injection device further comprises an inner housing intermediate the outer housing and at least part of the barrel and/or plunger, an energy source in communication with the inner housing, and blocking means capable of preventing said inner housing moving axially under the influence of said energy source.

Abstract: A system for the metering and delivery of small discrete volumes of liquid is comprised of a small or minimal number of inexpensive components. One such component is a movable member, such as a miniature precision reciprocating displacement pump head, which is driven by an actuator that comprises a shape memory alloy material. The operating mechanism of the system is of little or minimal complexity. The system facilitates the precise metering and delivery of the small discrete volumes of liquid. Potential applications for the system include subcutaneous, long-term, automated drug delivery, for example, the delivery of insulin to a person with diabetes. In such an application, the small, simple and inexpensive nature of the invention would allow for its use as both a portable and a disposable system.

Abstract: The present invention relates to a medical injection device (1) for use in combination with a medicament filled cartridge (2), the injection device being provided with a spring-assisted injecting mechanism where energy released from the spring moves a plunger (3) of a held cartridge (2). Sensor circuitry is adapted to detect speed related data during injection so at to detect an abnormal speed condition, such as a needle blocking condition, a priming condition or an air purge condition. The invention also relates to a medical injection device comprising sensor circuitry and user communicating means to provide a recommended needle retraction waiting period which is dependent on the speed of injection.

Abstract: The invention relates to an injection device comprising a housing, a container holder arranged within said housing, the container holder being configured for accommodating a medicament container having a needle attached to one end thereof and a stopper sealingly and slidable arranged inside the medicament container at the other end thereof, a drive unit comprising a plunger rod and plunger drive means, the plunger drive means being slidable arranged in relation to the plunger rod, being rotationally locked to the plunger rod and being rotatable in relation to the housing, said drive unit further comprising a first energy accumulating member arranged in the interior of the housing of the injection device and adapted to accumulate and store energy, wherein said plunger drive means is operationally associated with said first energy accumulating member, wherein the plunger drive means is releasable such that due to an output torque from said first energy accumulating member, the plunger drive means are allowed to

Abstract: The present invention relates to a device for automatic injection of a product comprising a container, a needle and a piston. The device includes a housing receiving the container, the container being movable with respect to the housing between an initial position and an insertion position, distally spaced relative to the initial position; a safety shield coupled to the housing and movable with respect thereto between a rest position, an activation position, proximally spaced relative to the rest position, and a safety position, distally spaced with respect to the rest position; biasing feature for causing the movement of the safety shield to the safety position; triggering feature for causing the container to move from its initial position to its insertion position, the triggering feature being releasable by movement of the safety shield to the activation position; and, isolating feature for isolating the safety shield from the biasing feature when the safety shield is moved to its activation position.

Abstract: An automatic retractable syringe includes a tubular body on which a syringe opening is provided; a piston body in whose pressing portion a vent hole VA is formed and in whose shaft portion a vent passage passing from the vent hole VA through inside to the front end portion is formed; and a spring which returns the pressed piston body to its original position. When the pressing portion is pressed by a thumb or other finger plugging the vent hole VA to move the piston body forward, air is supplied from the syringe opening. Subsequently, when the thumb or other finger is released, air flows into the tubular body through the vent hole VA and the vent passage, and the piston body automatically returns to its original position by the spring. Therefore, air can be consecutively supplied by repeatedly pressing the pressing portion.

Abstract: An infusion pump unit includes a housing sized to allow the pump unit to be carried as a portable unit. The housing contains a controllable pumping system for pumping fluid. The pump actuator is lighter, smaller, quieter and less power consuming.

Abstract: The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

Abstract: An autoinjector having an external shell (1022), a reservoir, a piston, a needle, a piston rod (1005) that is displaceable between a loaded position and an injection position in which the piston rod has displaced the piston of the reservoir to inject the fluid product through the needle, an injection spring (1008) to stress the piston rod towards the injection position, and a mobile element (1004; 1006), the piston rod displaceable relative to the mobile element. The autoinjector also includes an indication device (1500) having a key (1120), and a head part (1122). The mobile element including a deformable tab (1510; 1520), the head part cooperating prior to injection with the deformable tab to prevent any radial deformation, blocking the mobile element relative to the external shell. The piston rod, on completion of injection, exerting traction on the head part causing displacement of the key and enabling radial deformation of the deformable tab and axial displacement of the mobile element.