Abstract: An improved, very wieldy anesthetic syringe that allows for precise and repeated injection has a first hydraulic chamber behind a feed piston and a second hydraulic chamber behind the first hydraulic chamber, the hydraulic chambers being connected so as to allow for regulation of the flow resistance. A special receiver for cannulae that have been specifically developed for use with the proposed syringe is also provided.

Abstract: An wound treatment device includes a housing and a treatment tip. The housing retains a volume of treatment fluid. The treatment tip includes a recess, a peripheral edge surrounding the recess, and a fluid channel in view of communication with the recess and the volume of treatment fluid. The recess may be sized to enclose at least a portion of a wound such as an acne member on a person's skin. The recess is sized to retain a volume of the wound treatment fluid when the peripheral edge is sealingly engaged with a skin surface surrounding at least a portion of the wound.

Abstract: A catheter having a drug delivery unit at the distal end thereof. The drug delivery unit includes an actuator capable of assuming an activated and an inactivated configuration. The drug delivery unit also includes a receptacle capable of accepting a therapeutic agent. The actuator and receptacle are in communication with each other such that the actuator transmits force to the receptacle and the receptacle accepts force from the actuator in an activated configuration of the actuator. Also provided is a method of delivering a therapeutic agent to a target site using the catheter of the present invention.

Abstract: An apparatus for making and administering two non-homogenous liquids to target tissue includes a spray comprising two syringes for containing the first and second non-homogenous liquid where the syringes are adapted to be removably coupled to an applicator. The applicator includes a pair of elongated tubes each having a tubular sheath at a proximal end, a distal end and a lumen in which the pair of elongated tubes are disposed. The apparatus includes a regulator module having an inlet port adapted for connection to a source of gas under pressure and a gas outlet port adopted for connection to the gas inlet port of the sheet. A vent gas inlet port is adapted for connection to a vent port of an endoscopic cannula where the regulator vents a quantity of gas from the endoscopic cannula approximately equal to a quantity of gas introduced at the gas inlet port of the sheet.

Abstract: An elongated insertion tube can be provided having a wall having one or multiple layers. A layer of a wall can include composite material having healing agent storage structures that store healing agent material and a catalyst dispersed within a polymer matrix. The layer can be formed so that when force is imparted to the layer, healing agent material stored within a storage structure reacts with a catalyst and polymerizes, to heal damage imparted to the layer.

Abstract: A medication delivery cartridge is described that includes a casing having an internal cavity extending between a proximal end and a distal end of the casing, a plunger translatable within the internal cavity that includes a penetrable fluid outlet, a volume of medicine contained within the internal cavity disposed between the plunger and the proximal end of the casing, and a first penetrable sterility barrier spanning the internal cavity proximate the distal end of the casing. Related apparatus, systems, and methods are also disclosed.

Abstract: A medication delivery system includes an array of cartridge-receiving ports, a medication receiving fluid conduit, and a plurality of dispensing elements. Each port includes a fluid channel terminating at a fluid outlet and is configured to receive one of a plurality of cartridges that each contain a bolus volume of medication. The medication-receiving fluid conduit is fluidically coupled to the fluid outlet of each cartridge-receiving port at a first region and to a system outlet conduit at a second region (which in turn can be coupled to a patient catheter line). Each dispensing element corresponds to a single cartridge-receiving port so that, upon activation of the dispensing element, at least a portion of the bolus volume of medication flows through the fluid outlet of each cartridge-receiving port into the medication-receiving fluid conduit. Related apparatus, systems, and methods are also disclosed.

Abstract: Apparatuses for automatic medicament injection and methods for manufacturing automatic medicament injectors are described herein. In some embodiments, an apparatus includes a housing, a needle, an energy storage member, an actuator, a locking member, and a needle guard. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The energy storage member has a first configuration and a second configuration and is configured to produce a force when moving between its first configuration and its second configuration to move the needle from its first position to its second position. The actuator is configured to move the energy storage member from its first configuration to its second configuration.

Abstract: An apparatus includes a housing, a medicament container and an actuator. The actuator includes a release member and an energy storage member having a first position and a second position. In the first position, the energy storage member has a first potential energy. In the second position the energy storage member has a second potential energy. The energy storage member is configured to convert a portion of the first potential energy into kinetic energy when moved from the first position to the second position to move the medicament container within the housing. The energy storage member has a longitudinal axis offset from a longitudinal axis of the medicament container. The release member is configured to selectively deploy the energy storage member from its first position to its second position.

Abstract: An apparatus for producing medical foam having a foam generation unit including a fluid reservoir, a fluid delivery line and a foam generation tip; and a compressed gas unit including at least one container of compressed gas, a source of electric power, and a gas regulator valve.

Abstract: A system is provided for efficiently gelating and injecting a constant amount of biopolymer powder for effectively using biopolymer in sealing, stanching, and prevention of adhesion of a post-surgical site. Powder transfer line 320 for transferring biopolymer powder atomized with the pressure of noninflammable gas in powder agitating container 220, and transfer lines 310, 330 for separately transferring noninflammable gas and solution separately from the powder transfer line 320, are joined at the tip of nozzle attachment 400 for injecting a mixture of the biopolymer powder and the noninflammable gas, together with the noninflammable gas and the solution.

Abstract: An apparatus includes a cartridge having a liquid drug reservoir configured to hold a liquid drug and a volatile liquid reservoir configured to hold a volatile liquid. The cartridge is configured so that vaporization of at least some of the volatile liquid creates a flow of the liquid drug out of the liquid drug reservoir. The apparatus also includes a flow sensor configured to monitor the flow of the liquid drug, a liquid valve configured to regulate the flow of the liquid drug, and an insertion unit configured to deliver the liquid drug to a person. The cartridge may also include a vaporized gas chamber configured to hold the gas. The gas in the vaporized gas chamber expands and pushes the liquid drug out of the liquid drug reservoir.

Abstract: An object is to provide a medical liquid infusion apparatus suitable for a portable use and capable of suppressing an abrupt change in flow rate even when the environmental temperature rises. A medical liquid infusion apparatus 1 is provided with a driving portion 2 and configured to infuse a medical liquid inside a medical liquid container 3 to a patient by applying a pressure to the medical liquid container 3 using a driving force of the driving portion. The driving portion 2 includes a compressed gas cylinder 4 filled with a compressed gas, and it is configured in such a manner that the driving force is generated by the pressure inside the compressed gas cylinder 4.

Abstract: A device for delivery of a foamable composition to a body cavity includes a pressurized composition reservoir; a hollow body having a longitudinally extending wall and having at least one aperture provided through a wall of said body, the proximal end in fluid communication with the reservoir for receiving a foamable composition from said composition reservoir; and an actuator operatively connected to the composition reservoir for effecting release of a foamable composition from said composition reservoir into a body cavity through said hollow body; wherein said body has a length less than about 125 mm and internal diameter in the range of about 1.5 mm to about 3.5 mm, wherein said length and internal diameter are selected to provide a delivery of at least about 70% of the foamable composition during operation. The foam delivery device can have multiple apertures.

Abstract: A reservoir unit (200) is provided comprising a housing (201) in which a reservoir (250) with a transparent portion (251) is arranged, the housing comprising a window (203) allowing a portion of the reservoir to be inspected. The reservoir unit is adapted to be moved from a first “cold” condition to a second “warm” condition with no visible water condensing on the interior surface of the window portion. Further, a vent (210, 211) is adapted to provide pressure equalization between the interior of the housing and the exterior. In this way it is possible to perform visual inspection of the reservoir at all times without being confused by dew or condensed water drops, e.g. when a prefilled reservoir unit containing a drug which requires storage at a given low temperature, as is the case for insulin-containing drugs, is taken out in ambient temperature.

Abstract: An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration.

Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.

Abstract: A lotion applicator which provides total, even coverage of the back of the user and does not require manual dexterity or stretching, consisting of a door mount, rotor, rotor guide, and one or more pads. The door mount is attached to a vertical surface, preferably a door, but the device can also be mounted to a wall. The user stands with her back against the device and, raising her arms to about shoulder level, grabs a handle attached to the rotor guide and pushes up, thus lifting the rotor guide. The rotor travels with the guide, whereupon one or more pads, which are impregnated with lotion and attached to the rotor in an off-center position, spin along the back of the user, spreading lotion.

Abstract: A vascular access device within an external environment may include a body and a septum at least partially housed within the body, a gas chamber housed within the body and the septum, and a vent adjacent the body capable of facilitating gas transfer between the gas chamber and the external environment. A method of venting a gas chamber within a medical device includes transferring gas between the gas chamber and an external environment of the device through a vent that is adjacent the body of the device.

Abstract: A portable debridement and irrigation device includes a body structure and a disposable spray nozzle structure and spray reduction cup removably mounted thereon. A battery-powered electric pump device is in liquid transmission connection with the disposable spray nozzle device. A removable and replaceable liquid storage container which holds a sterile liquid is held within a storage container receiving chamber formed within the body structure in liquid transmission connection with the electric pump, and a pump engagement switch is operatively interposed between the battery and the electric pump for engaging and disengaging the electric pump. Finally, a pump speed control device with a limiting device for preventing it from proceeding beyond a predetermined operating setting unless the operator intentionally disengages the limiting device is operatively connected to the electric pump for adjusting the operating speed of the pump and thus the outflow speed of liquid from the spray nozzle.

Abstract: The technical field of the invention is that of needleless syringes used for intradermal, subcutaneous or intramuscular injections of active principle for therapeutic purposes. More particularly, the invention concerns a needleless syringe (10) comprising a propelling system, the active principle and an application guide (8), mainly characterised in that the propelling system consists of an impact wave generating device (3) and the active principle is arranged in at least a blind cavity (7) of the downstream surface (6) of a barrier (4) extended by the application guide (8). Thus, the active principle is expelled in the form of streamlined jets, driven at very high speed.

Abstract: The treatment of ungual and subungual diseases is disclosed.

Abstract: The present invention is directed to a modular pressure infuser apparatus adapted to allow a user to modify the configuration of the pressure infuser apparatus by utilizing one or more interchangeable manual and/or automatic pumps to inflate a pressure infuser bag of the pressure infuser apparatus. The modular configuration of the pressure infuser apparatus permits the user to detach and reattach a motorized pump and/or a manual pump to the pressure infuser bag quickly, easily, and efficiently without decreasing the air pressure of the pressure infuser bag. By providing selectively removable pump modules, the user can select the configuration of the pressure infuser apparatus that is best adapted to the needs of the patient. A pressure release valve is configured to regulate the pressure of the pressure infuser bag.

Abstract: An implantable infusion device (10) includes a lightweight, inert housing (12) which contains an infusate (18) for administration to a patient, and an enclosed, gas-impermeable variable volume chamber (30) which contains a pressure source, such as propellant, mechanical spring, or the like. The variable volume chamber may be in the form of a rigid-walled expandable bellows structure or a nonstretchable flexible bag and is attached to the housing so as not to obstruct the entry port for introduction of infusate. A recharging fluid flow path (31) is provided adjacent to where the variable volume chamber is attached to the housing. The infusate is delivered from the device via a catheter in response to expansion of the variable volume chamber against the volume of infusate in the housing. A separate bolus injection port (38) is provided which allows infusate to be safely introduced directly into the catheter and overrides the controlled pressure-driven delivery.

Abstract: The present invention relates to a jet injector system with a hand piece. The present invention generally comprises a power unit, a medicine unit, an energy unit, a supply bottle, and a hand piece. The hand piece and power unit may be separate components connected to each other by a high pressure hose, which gives the user more flexibility. A valve assembly having a ball lock assembly and a needle assembly controls the release of medication from the high pressure hose into the hand piece and out a nozzle into the subject.

Abstract: The present invention provides a fluid injection apparatus for injecting viscous fluids directly from a syringe in which it is commercially delivered. The fluid injection apparatus includes a cylindrical syringe sleeve into which the syringe is inserted from one end with a small hole at the other end of the sleeve through which the syringe needle or cannula protrudes. The apparatus includes a locking head assembly for retaining the syringe in the cylindrical syringe sleeve which includes a top plate and a locking flange which engages with the flange for locking the head assembly to the cylinder. The plunger in the syringe is discarded and when the locking head assembly is placed on the cylindrical syringe sleeve an internal flange with a gasket located on it is inserted into the top of the syringe chamber forming a seal.

Abstract: A veterinary pill/capsule delivery device comprised of a dispensing head for holding a pill or capsule, the dispensing head being attached to the end of a syringe component for ejecting the pill or capsule out from the dispensing head into the animal's mouth while at the same time injecting a quantity of water into the mouth. The syringe component includes a push-rod that protrudes into dispensing head for ejecting the pill/capsule therefrom, plus water release holes near the dispensing head for simultaneously jetting water out of the syringe component into the animal's mouth, thereby compelling the animal to swallow the pill.

Abstract: The invention concerns a needleless syringe (1) comprising a trigger, a gas generator (2) prolonged by a gas expansion chamber (3), a system for retaining particles and an ejection tube (4). The invention is characterised in that the particles are housed outside the ejection tube conduit (4) and the gases cause the particles to reach inside said tube (4) by displacing a plunger (13), prior to speeding them up by wave shock inside the tube (4).

Abstract: The invention provides a continuous liquid infusion device in which liquid syringe and a negative pressure cylinder are separable to use a liquid infused syringe. This continuous liquid infusion device includes: a negative pressure cylinder having a barrel part including an open/close valve at its tip and leg parts extending from a base end thereof; a piston air-tightly fitted in the barrel part and connected to a base end of an outer case covering an outer surface of the barrel part, through slots between the leg parts; a liquid syringe having a liquid infusion/discharge port at its tip, and a base end screwed with the outer case so that the liquid syringe is positioned back to back with the negative pressure cylinder; and a movable unit liquid-tightly fitted to an inner circumference of the tip of the liquid syringe and abutting against a base end of the leg parts.

Abstract: A device and method for providing a suspended agent such as a contrast agent without mechanical resuspension. A volume of agent is divided into sub-volumes in a network configured to suspend and deliver the sub-volumes of agent to a patient when a propellant fluid flows through the network. The invention reduces sedimentation of agents into one or a few aggregates and eliminates a mechanical mixing step. The invention thus provides a uniformly suspended agent, improving patient health and safety and increasing cost and time savings.

Abstract: The present invention is directed to a modular pressure infuser apparatus adapted to allow a user to modify the configuration of the pressure infuser apparatus by utilizing one or more interchangeable manual and/or automatic pumps to inflate a pressure infuser bag of the pressure infuser apparatus. The modular configuration of the pressure infuser apparatus permits the user to detach and reattach a motorized pump and/or a manual pump to the pressure infuser bag quickly, easily, and efficiently without decreasing the air pressure of the pressure infuser bag. By providing selectively removable pump modules, the user can select the configuration of the pressure infuser apparatus that is best adapted to the needs of the patient. A pressure release valve is configured to regulate the pressure of the pressure infuser bag.

Abstract: The present invention is directed to a modular pressure infuser apparatus adapted to allow a user to modify the configuration of the pressure infuser apparatus by utilizing one or more interchangeable manual and/or automatic pumps to inflate a pressure infuser bag of the pressure infuser apparatus. The modular configuration of the pressure infuser apparatus permits the user to detach and reattach a motorized pump and/or a manual pump to the pressure infuser bag quickly, easily, and efficiently without decreasing the air pressure of the pressure infuser bag. By providing selectively removable pump modules, the user can select the configuration of the pressure infuser apparatus that is best adapted to the needs of the patient. A pressure release valve is configured to regulate the pressure of the pressure infuser bag.

Abstract: Disclosed is an injector assembly having driving means for injecting a substance into a subject and locking means for retaining the driving means until a predetermined amount of pressure builds in a cavity near the driving means.

Abstract: The present invention provides a fluid injection apparatus for injecting viscous fluids directly from a syringe in which it is commercially delivered. The fluid injection apparatus includes a cylindrical syringe sleeve into which the syringe is inserted from one end with a small hole at the other end of the sleeve through which the syringe needle or cannula protrudes. The apparatus includes a locking head assembly for retaining the syringe in the cylindrical syringe sleeve which includes a top plate and a locking flange which engages with the flange for locking the head assembly to the cylinder. The plunger in the syringe is discarded and when the locking head assembly is placed on the cylindrical syringe sleeve an internal flange with a gasket located on it is inserted into the top of the syringe chamber forming a seal.

Abstract: A system for injecting DNA-based medications into humans is provided by the present invention. The system includes a needle-free injector with an injection orifice of approximately 0.004 inches for supplying DNA-based medication at an initial pressure of from 3900 to 4300 psi, and then immediately declining to a level of about 2800 to 3800 psi, and then immediately cutting off pressure to terminate the injection. The injector includes an annular adapter for spacing the injection orifice from the skin of the patient. The adapter includes an abutment against which the injector is disposed so that the orifice is spaced approximately 0.76-1.0 inch from the skin of the patient, the adapter having an inner diameter at the distal end of approximately 0.50-0.70 inches.

Abstract: A gas-powered, durable, needle-less hypodermic jet injection device (10, 210) includes a hand-held injector (12, 212) which receives into an injection cylinder a volume of liquid medication to be injected in the form of a high velocity jet capable of penetrating the skin without the use of a hypodermic needle. The injection device provides an injection orifice, and an injection piston. Forceful movement of the injection piston causes a high velocity injection jet of liquid medication to be expelled from the injection cylinder via the injection orifice. The injection device includes features which improve its usability, particularly for users with hands that are possibly weak, feeble, or arthritic, for example; and also includes additional features which improve manufacturability, durability, and cost effectiveness of the device.

Abstract: A transdermal medication delivery device (20) for the remote controlled administration of medications (68, 70, 72) for absorption through the skin of a patient (22) includes a tubes (62) containing the medications (68, 70, 72). Tubes (62) are in fluid communication with valve inlets (76, 82, 88) of valves (74, 80, 86) formed on a micro-electro-mechanical-system-based (MEMS-based) valve chip (64, 162). A medication delivery component (26, 176) in fluid communication with valve outlets (78, 84, 90) of valves (74, 80, 86) has a surface (66, 178) adapted to be in contact with the skin of the patient (22) when in use. A controller (92) is configured to control a flow of the medications (68, 70, 72) through the valves (74, 80, 86), and a wireless communication interface (94), in communication with the controller (92), is configured to receive a medication control message (96) from a remote location (32).

Abstract: A needleless syringe comprising a body containing a lumen, an upstream end of which is, or is arranged to be, connected to a source of gaseous pressure which can suddenly be released into the lumen; the downstream end of the lumen terminating behind a bistable diaphragm which is movable between an inverted position in which it presents outwardly of the body a concavity for containing particles of a therapeutic agent, and an everted, outwardly convex, position; the arrangement being such that, in use, when gas under pressure is released into the lumen, the diaphragm will snap over from its inverted to its everted position and catapult the particles outwardly.

Abstract: An implantable infusion device includes of a disc-shaped housing that is made from a biocompatible material and contains a reservoir. The reservoir defines a chamber that contains at least one flexible diaphragm. A ring is provided in alignment with the peripheral edge of each diaphragm. The ring has a central opening that is aligned with the convolution and central portion of each diaphragm, to allow the diaphragm to flex within the ring. In this manner, the volume on one side of each diaphragm may be varied to correspond to a varying volume of infusion medium. Similarly, the volume within the reservoir chamber on the other side of the diaphragms is varied as the diaphragms flex, to correspond to the expansion and contraction of a propellant medium within the reservoir.

Abstract: A method for injecting a fluid medicament into a patient uses a syringe having a plunger that can be advanced into the syringe chamber. As the plunger is advanced, the medicament is expelled from the chamber through an injection tube that extends from the chamber. Preferably, the injection tube is formed as a cone-shaped funnel with a taper of generally decreasing radius in a distal direction. The steps for the method include creating a gas pocket in the distal portion of the injection tube. Then, as the plunger is advanced into the chamber to accelerate the fluid medicament through the injection tube, the gas pocket allows the accelerating fluid medicament to gain momentum. The change in this momentum as the fluid medicament collides with the skin will generate an impulse force that is manifested as an initial pressure spike. This pressure spike creates a hole in the skin of the patient as the fluid medicament exits the tube.

Abstract: The present invention is directed to a modular pressure infuser apparatus adapted to allow a user to modify the configuration of the pressure infuser apparatus by utilizing one or more interchangeable manual and/or automatic pumps to inflate a pressure infuser bag of the pressure infuser apparatus. The modular configuration of the pressure infuser apparatus permits the user to detach and reattach a motorized pump and/or a manual pump to the pressure infuser bag quickly, easily, and efficiently without decreasing the air pressure of the pressure infuser bag. By providing selectively removable pump modules, the user can select the configuration of the pressure infuser apparatus that is best adapted to the needs of the patient. A pressure release valve is configured to regulate the pressure of the pressure infuser bag.

Abstract: A human growth factor delivery system for use in connection with dermabrasion includes a source of human growth factors in fluid. The growth factor fluid may be applied to the target skin area simultaneously with the step of abrading the skin by a single handpiece. Furthermore, the fluid is caused to penetrate by a combination of the abrasive elements, a vacuum, and a positive pressure applied in bursts, which produces a massaging effect. The fluid source may be contained in a removable cartridge adapted to fit within the handpiece. The fluid is drawn from the cartridge by the vacuum. The vacuum also draws a portion of target skin into a space of the handpiece for contact with an abrasion element. The vacuum furthermore draws excess fluid and removed skin cells into a disposable or reusable canister.

Abstract: A pressurised gas powered actuator comprising a piston (3) operating in a cylinder (1). The stroke of the piston (3) may be reduced by uncovering one or more holes (14, 20) in the cylinder wall to permit the escape of the pressurised gas at a predetermined position along the swept wall of the cylinder. Alternatively, the piston (401) may be connected to a rod (402) which has a gas vent (406) formed therein, the position of the rod (402) with respect to the piston (401) being variable to adjust the stroke of the piston (401).

Abstract: A needle-less injector suitable for injecting fluid through a surface includes a housing, a driver, an engine and a trigger. The housing contains a fluid and the engine contains a compressed gas. Upon application of sufficient force to the trigger, the compressed gas is released from the engine forcing the driver through the interior of the housing, expelling the liquid from the housing at a speed sufficient to pierce an injection surface. In one embodiment, the needle-less injector includes a mechanism for mitigating the kickback associated with releasing compressed gas from the engine. In another embodiment, the housing includes finger rests that provide stability and resistance to activate the device. In another embodiment, the engine is fitted with a reusable valve.

Abstract: In accordance with the current invention, a needle-free injection system includes a cap that has a first seal for sealing an injection orifice when the cap is engaged with an injection end of the system. The cap also includes a push-rod for facilitating priming of the system when engaged with a priming end of the system. The system also includes a push-rod engaging mechanism disposed at the priming end of the system for receiving the push-rod for priming the system. The system further includes a gas cylinder for supplying pressurized gas for injecting, via the injection orifice, an injectate initially disposed within a storage chamber, and a sealing system for preventing the pressurized gas from ejecting the injectate from the system prior to actuation of the system. Actuation of the system is achieved via a slidable trigger plate.

Abstract: The microneedle devices disclosed herein in some embodiments include a substrate; one or more microneedles; a reservoir for delivery of drugs; a gas source, and, optionally, pump(s), sensor(s), and/or microprocessor(s) to control the interaction of the foregoing.

Abstract: The invention provides a continuous liquid infusion device in which liquid syringe and a negative pressure cylinder are separable to use a liquid infused syringe. This continuous liquid infusion device includes: a negative pressure cylinder having a barrel part including an open/close valve at its tip and leg parts extending from a base end thereof; a piston air-tightly fitted in the barrel part and connected to a base end of an outer case covering an outer surface of the barrel part, through slots between the leg parts; a liquid syringe having a liquid infusion/discharge port at its tip, and a base end screwed with the outer case so that the liquid syringe is positioned back to back with the negative pressure cylinder; and a movable unit liquid-tightly fitted to an inner circumference of the tip of the liquid syringe and abutting against a base end of the leg parts.

Abstract: A device for transdermal delivery of a composition includes a housing partitioned into a delivery chamber arranged to contain the composition and a detonation chamber mechanically coupled to the delivery chamber. The detonation chamber is intended to contain an energetic material producing an impulse transient in response to a detonating stimulus. The housing is coupled to an energy coupling element, or detonator, for communicating energy provided by an external energy source into the detonating stimulus in the detonation chamber. The detonator can detonate the energetic material by causing an electrical discharge or spark within the detonation chamber. The detonator can be a piezoelectric film in electrical communication with the energetic material.

Abstract: The present invention relates to a jet injector system with a hand piece. The present invention generally comprises a power unit, a medicine unit, an energy unit, a supply bottle, and a hand piece. The hand piece and power unit may be separate components connected to each other by a high pressure hose, which gives the user more flexibility. A valve assembly having a ball lock assembly and a needle assembly controls the release of medication from the high pressure hose into the hand piece and out a nozzle into the subject.

Abstract: A dental instrument includes a pneumatic pressure intensifier that supplies a handpiece having an orifice to generate a high velocity liquid jet. A pneumatic system includes valves to supply the pressure intensifier and control the output to the handpiece. A jet forming assembly includes an orifice mount in the handpiece, and a guide tube assembly secured to the orifice mount. The guide tube assembly is variably positioned to select the minimum distance from the jet orifice to the tissue target, so that the jet force may be controlled.