Abstract: A syringe assembly including a syringe barrel having a first end, a second end, and a sidewall extending therebetween defining a chamber is disclosed. The syringe assembly includes a stopper disposed within the chamber of the syringe barrel and a plunger rod having an inner member engaged with the stopper and an outer member adapted for telescopic movement with respect to the inner member. The plunger rod is transitionable from a collapsed position, in which a portion of the inner member is nested within the outer member, to an extended position, in which the same portion of the inner member extends outside the outer member. The syringe assembly also includes a stop member configured for cooperation with a portion of the syringe barrel, upon relative movement of the outer member with respect to the inner member, to limit the outward travel of the plunger rod from the syringe barrel.

Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes at least one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has a first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.

Abstract: The present application relates to a disposable auto injector (10) that can be safely operated for automatic injection of a dose of medication and having a housing (12) for accommodation of a syringe (18) with a needle (20), the syringe being movably positioned in the housing between a first position in which position the needle is accommodated inside the housing and a second position in which position the needle protrudes outside the housing (22), a driver configured for applying a force to the syringe thereby moving the syringe from the first position to the second position, and wherein the driver is also configured for applying a force to the syringe thereby moving the syringe from the second position to a retracted position in which position the needle is accommodated inside the housing upon user operation of a release member (42).

Abstract: The present invention relates to a piston rod assembly for a drug delivery device, comprising: a piston rod adapted to be operably engaged with a piston of a cartridge containing a medicament, at least one adjusting member displaceably disposed at the piston rod with respect to the piston rod's long axis, and being interconnected with a distal end section of the piston rod, and at least one interlock means adapted to interact with the adjusting member and/or with the piston rod for mutually locking in position the adjusting member and the piston rod in an arbitrary relative position in order to compensate for tolerances of manufacture and/or of assembly.

Abstract: A replaceable needle assembly is provided for a retractable syringe comprising a barrel and a plunger, whereby the retractable needle can be replaced by a user without affecting the retraction mechanism. A mounting member is removably mountable to the barrel by way of a screw-thread connection and a needle mount is removably coupled to the mounting member. A needle is mounted to the needle mount. The barrel comprises a needle mount retainer that comprises a plurality of fingers that engage the retractable needle mount to prevent inadvertent retraction. The plunger comprises a collapsible seal which maximizes the efficiency of fluid delivery prior to the plunger engaging the retractable needle mount for retraction. An initially compressed spring decompresses to drive retraction of the plunger and the engaged needle mount. A lock formed between the plunger and barrel prevents further use of the plunger after retraction.

Abstract: A retractable syringe, plunger and releasable needle retaining assembly are provided. The retractable syringe typically has a glass barrel and is prefilled with fluid contents before use. The releasable needle retaining system comprises a retractable needle, a needle seal, a retaining member and an ejector member that is operable to release the retractable needle from the retaining member. The retaining member has a mating surface for mounting to a complementary mating surface of an interior wall of a syringe barrel. The plunger comprises a plunger outer, a plunger rod frangibly connected to a controlling member, a spring and a unitary plunger seal capable of engaging the retractable needle, wherein the plunger rod, plunger outer and the controlling member co-operate to releasably maintain the spring in an initially compressed state. After delivery of fluid contents of the syringe, the plunger forces the ejector member to release the retractable needle from the retaining member.

Abstract: The present invention relates to a piston for a cartridge for a drug delivery device comprising: at least one annular sealing surface to radially abut against an inner side wall of a cartridge, a distal surface to confine a drug receiving volume of the cartridge, a thrust receiving surface adapted to receive a thrust exerting plunger of a drug delivery device for displacing the piston in a proximal direction relative to the side wall, wherein the thrust receiving surface comprises numerous centering elements protruding from the thrust receiving surface towards the plunger and wherein the centering elements comprise an outer shape and geometry that matches with a corresponding receptacle of the plunger, and wherein the centering elements are arranged and aligned on the circumference of an imaginary annular or circular structure.

Abstract: A gasket of a prefilled syringe is disclosed, which includes a gasket body and a plunger-mounting member. The gasket body has a plunger-mounting member removal prevention rib formed on an inner surface of the gasket body. The plunger-mounting member has an outer projected part, which engages the plunger-mounting member removal prevention rib of the gasket body, a plurality of elastically deformable inner projected parts which are extended obliquely from an inner portion of a proximal side of the plunger-mounting member toward a central and distal end of the plunger-mounting member, and plunger removal prevention locking parts formed at free ends of the inner projected parts. The plunger has a distal end part capable of entering the plunger-mounting member and an outer projection part which engages the plunger removal prevention locking parts of the plunger-mounting member.

Abstract: An injection device (110) is provided which includes a syringe (122) having a discharge nozzle (118). The syringe is movable between a retracted position in which the discharge nozzle is contained within the housing and an extended position in which the discharge nozzle extends from the housing. A trigger (114) is activatable to allow the contents of the syringe to be discharged through the discharge nozzle. There is also a releasable locking mechanism (116) which, when engaged, prevents the trigger from moving into an active position. The trigger includes a first portion (150) having a cut-out (152) which extends from a first end of the trigger in a direction substantially parallel to the first axis (101). The releasable locking mechanism includes a protrusion (154) along a second axis (181) for communicating with the first portion of the trigger when the releasable locking mechanism is engaged and for communicating with the cut-out when the releasable locking mechanism is disengaged.

Abstract: A system to minimize fluid turbulence inside a tissue cavity during endoscopic procedures. A body tissue cavity of a subject is distended by continuous flow irrigation using a solenoid operated pump on the inflow side and a positive displacement pump, such as a peristaltic pump, on the outflow side, such that the amplitude of the pressure pulsations created by the outflow positive displacement pump inside the said tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method for accurately determining the rate of fluid loss into the subject's body system during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors. The present invention also provides a system of creating and maintaining any desired pressure in a body tissue cavity for any desired cavity outflow rate.

Abstract: A single-use auto-disable syringe device of reduced size utilizes a locking element to prevent re-use of the syringe by locking the plunger rod with respect to the barrel upon completion of an injection stroke. The plunger rod includes a plurality of teeth comprising distally facing shoulders provided on a majority of the length of an elongate portion of the plunger rod and a breakable section configured to break upon the application of excessive axial or torsional force. The breakable section is preferably provided at a distal end of the plunger rod so that a proximal end of the locking element engages the syringe barrel and plunger rod at a position more proximal than the breakable section. In this way, the locking element resists some of the force that would otherwise be applied to the breakable section if the plunger rod were twisted.

Abstract: A syringe including a front end and a rear end. A front portion of the syringe having an axially extending hollow needle that projects from the front end. The rear end of the needle is in fluid communication with a space that extends substantially to the rear end of the syringe. A plunger extends axially and is movable to and fro in the space and is designed such that, when drawn out, it sucks liquid through the needle and, when pressed in, discharges liquid through the needle. A radially projecting flange element in the front portion of the syringe is designed in such a way that it can be gripped between the thumb and middle finger of a user's hand. The syringe is dimensioned so as to permit injection using the index finger of the same hand. A capsule device for at least partially accommodating a syringe. A syringe device.

Abstract: A casing for an injection device of the type having a safety device which prevents operation of the device, incorporating an actuator means by which the safety means of the device can be actuated to allow operation of the device. Also a casing for a medicament container having an opening closed prior to use by a break-off tip, having relatively moveable first and second casing parts, which on relative movement apply a breaking force to the break-off tip. A preferred embodiment includes both such features.

Abstract: A risk of injection liquid contamination due to contact of injection liquid in an injection-liquid filled area in a barrel with the surface in an injection-liquid unfilled area in the barrel by causing a plunger of a prefilled syringe to be inadvertently withdrawn by mishandling which may leads to medical malpractice, is eliminated by the invention. Withdrawal of a plunger 14 is limited by engagement of a barrel 12 in which a withdrawal-limiting member 48 is provided and a the plunger 14 in which a withdrawal-limiting member 54 is provided. As a result of this, contact of the injection liquid L prefilled to a liquid-filled area 32 in the barrel 12 with the surface of a liquid-unfilled area 34 in the barrel by withdrawal of the plunger 14 is prevented.

Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes a one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has as first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.

Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.

Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes a one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has as first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.

Abstract: A retractable syringe (11) and plunger (20) therefore are provided, whereby the plunger comprises a controlling means (62) which facilitates control of the rate of retraction of the retractable needle. By controlling the rate of needle retraction, the likelihood of blood spattering is reduced, thereby improving the user-friendliness and appeal of the retractable syringe. Typically, the syringe is a prefilled syringe. Following plunger depression, a symmetrical ejector member (92) releases the retractable needle (40) from a retaining member (30) to thereby allow retraction of the retractable needle. Needle retraction is facilitated by a biasing means (70), such as a spring or other compressible and/or de-compressible device. The plunger comprises a plunger housing (21), in which is located the controlling means. The controlling means may be a pneumatic air space (324) inside the plunger housing which automatically acts against the retracting needle to thereby control or regulate the rate of retraction.

Abstract: A syringe includes a syringe cylinder, a sealing plug movably disposed within the syringe cylinder, and with a plunger cooperating with the sealing plug. A safety device prevents a sliding back of the sealing plug within the syringe cylinder in any position the sealing plug assumes within the syringe cylinder. The safety device has a locking element which engages at the plunger in any position the plunger assumes within the syringe cylinder. The locking element is attached to a retaining fixture and protrudes from the retaining fixture same such that an attachment point of the locking element is closer to the sealing plug at the retaining fixture than the free end of the locking element opposite of the attachment point.

Abstract: The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle.

Abstract: The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle.

Abstract: A syringe designed with a passive safety locking means to effectively and reliably disallow unintentional displacement of the plunger toward the distal end if the syringe. The safety locking means is designed to affect reliable automatic release on at least two (2) points of engagement of the syringe for its intended use namely the controlled dispensement of generally viscous substances therein.

Abstract: A safety syringe adapted consists of an outer casing that supports a conventional hypodermic needle and an inner casing which supports a blunt cannula that is disposed inside the inner lumen of the hypodermic needle. The inner casing is keyed to the outer casing by one or more pins that engage helical tracks formed along the inner surface of the outer casing. Rotation of the inner casing relative to the outer casing advances the inner casing so that the blunt cannula is moved from a retracted position within the needle to an extended position in which the blunt end of the cannula extends beyond the tip of the needle.

Abstract: A syringe cylinder comprising an interior space, having a stopper that can be displaced in the interior space and delimits an active ingredient space, is proposed. The syringe cylinder is characterized by an indicator device biuniquely indicating a longitudinal movement of the stopper occurring in one direction.

Abstract: A prefilled ready-to-use syringe, including a tubular body having, at its distal end, a tip to take a needle and, at its proximal end, a flange, a piston able to slide inside the tubular body and defining, with the tubular body, an internal working volume at least partially filled with a liquid, a rod for actuating the piston extending beyond the proximal end of the tubular body, characterized in that a rigid cover is attached and fixed in a definitive way to the flange and has a central opening for the free translational passage of the actuating rod, and the said cover forms a stop for the actuating rod in the proximal direction, and a plug is arranged to translate freely in the tubular body between the piston and the proximal end of the body, the plug being resistant to puncturing with a needle.

Abstract: A two-chambered, sequentially injectable syringe is disclosed. The syringe has two concentric barrels, substantially cylindrical in shape. The outer barrel has an open end adapted for receiving an inner barrel/first piston. The inner barrel/first piston contains a flushing liquid. The syringe has a second piston slidably movable in the inner barrel and a latching mechanism that can alternate between a locked configuration and an unlocked configuration. In the locked configuration, the latching mechanism prevents the second piston from substantially all longitudinal movement relative to the inner barrel. In the unlocked configuration, the latching mechanism permits longitudinal motion of the second piston within the inner barrel.

Abstract: A two-chambered, sequentially injectable syringe is disclosed. The syringe has two concentric barrels, substantially cylindrical in shape. The outer barrel has an open end adapted for receiving an inner barrel/first piston. The inner barrel/first piston contains a flushing liquid. The syringe has a second piston slidably movable in the inner barrel and a latching mechanism that can alternate between a locked configuration and an unlocked configuration. In the locked configuration, the latching mechanism prevents the second piston from substantially all longitudinal movement relative to the inner barrel. In the unlocked configuration, the latching mechanism permits longitudinal motion of the second piston within the inner barrel.

Abstract: A syringe (10) has a plunger (20), a barrel (11) and a collar (40, 50) with two pawls (42A, 42B). The plunger has two opposed ratchets (23A, 23B) that align with the one each of the pawls and thereby or impede, withdrawal of the plunger during or following depression of the plunger. The barrel has a collar with an inner (50) and an outer member (40) that are incapable of rotation relative with respect to each other. The outer member has the two pawls (42A, 42B) and two fingers that slidably engage opposed guide slots (28) on the plunger to thereby prevent or minimize rotation of the plunger relative to the collar. The inner member of the collar is operable to prevent engagement of the plunger ratchet by the two pawls until the plunger is depressed.

Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.

Abstract: A centering syringe plunger guide (140) includes a guide body (141) including a proximal end (142) and a distal end (149), a coupling bore (143) extending partially into the guide body (141) from the proximal end (142), a precision guide bore (144) extending partially into the guide body (141) from the coupling bore (143), with the precision guide bore (144) adapted to fit over a barrel precision diameter of a syringe barrel and hold the centering syringe plunger guide (140) in a predetermined substantially coaxial alignment with the syringe barrel, and a guide plunger bore (145) extending completely from the precision guide bore (144) to the distal end (149) of the guide body (141). The guide plunger bore (145) is adapted to receive a syringe plunger and is configured to substantially center the syringe plunger in a plunger bore of the syringe barrel.

Abstract: A spring retainer (60) for a syringe (10) that has a barrel (40), a plunger (20), a spring (90) and a retractable needle (50) that can couple with the plunger for spring-driven retraction of the coupled needle and plunger. The spring retainer has first (70) and second (80) body members that cooperate to releasably maintain the spring in a compressed state until the plunger is coupled to the retractable needle after depression of the plunger to deliver the fluid contents of the syringe. Depression of the plunger triggers rotational disengagement of the first and second body members to allow decompression of the spring which forces retraction of the needle into the barrel. Rotational disengagement of the first and second body members also assists rotation of the plunger into a final, inoperable position.

Abstract: A flush syringe assembly comprises a barrel including a cylindrical side wall having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end including an elongate tip extending distally therefrom having a passageway in fluid communication with the chamber. A plunger including an elongate body portion has a stopper at its distal end. The stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for driving fluid out of the chamber. The distal end of the stopper is configured to collapse while fluid is being driven though the passageway through motion of a plunger and to continue to drive fluid through the passageway after motion of the plunger has stopped.

Abstract: A plunger rod useful for sliding a piston inserted in a syringe barrel has a threaded portion formed at an end of the plunger rod to attach the piston on the plunger rod and a flange formed at an opposite end of the plunger rod. The threaded portion and the flange are integrally connected together by a cylindrical member having an outer diameter such that the cylindrical member can be inserted with contact slidability in the syringe barrel, for example, an outer diameter equal to or slightly smaller than an inner diameter of the syringe barrel.

Abstract: A spray or injection device that includes a casing or a pusher that includes at least one tab radially moveable between a first radial position, in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position and then allow it to return to the first radial position. The pusher or the casing further includes at least one stop between the pusher and casing to delineate the end of a first stroke corresponding to a first dose of medicament, and the beginning of a second stroke corresponding to a second dose of medicament.

Abstract: A syringe has a syringe barrel into which a plunger stopper is inserted during a manufacturing process. A plunger rod is connected to the plunger stopper, and a backstop for preventing inadvertent removal of the plunger stopper from the syringe barrel is arranged at the proximal end of the syringe barrel. The backstop and the plunger rod are configured to form a combined assembly component which is adapted to be mounted to the syringe barrel in a combined manufacturing step. After mounting the combined assembly component to the syringe barrel, the backstop and the plunger rod are separated to allow conventional use of the syringe.

Abstract: An administration instrument for medical use performs injection of a drug solution with stability and with great reliability. The administration instrument includes a needle that does not wobble, thereby alleviating physical and mental pain of the administration patient. The structure includes an injection button that is pressed at an angle that is not parallel to the needle with respect to a direction in which the needle is inserted into the skin. Thus, it is possible to prevent the force of pressing the injection button from being transmitted in a direction of insertion of the needle so that the needle is inserted deeper into the skin than the initial insertion of the needle, thereby achieving administration under a stable state.

Abstract: A casing (50) for an injection device (10) of the type having a safety device which prevents operation of the device (10), incorporating an actuator means (56) by which the safety means of the device (10) can be actuated to allow operation of the device (10). Also a casing (50) for a medicament container having an opening closed prior to use by a break-off tip (135), having relatively moveable first and second casing parts (51, 52), which on relative movement apply a breaking force to the break-off tip (135). A preferred embodiment includes both such features.

Abstract: A syringe assembly having passive disabling structure includes a barrel and a plunger rod assembly. The plunger rod assembly includes a plunger rod and a stopper connected by an indexing locking element. The number of strokes of the syringe plunger before the stopper is locked into the barrel rendering the syringe assembly unusable is determined by the number of detents on the plunger rod and stopper which engage the locking mechanism. Upon completion of the final delivery stroke, any attempt to withdraw the plunger rod from the barrel will cause the locking element to engage the barrel and trap the stopper in the barrel preventing further use of the syringe.

Abstract: To provide a syringe with a needle storage mechanism in which the needle storage mechanism is not activated before use. A safety syringe including an injection barrel 1 having a connecting portion 11 at the distal end and an opening at the proximal end thereof, a needle assembly B having an injection needle 5 and a needle base 6 fixed to the proximal end of the injection needle 5 and being connected to the connecting portion 11, a gasket 2 provided liquid-tightly and slidably in the injection barrel, a plunger 3 being connected to the proximal end of the gasket 2 and joining means 21 provided at the distal portion of the gasket 2 or the plunger 3, and joined means 61 provided at the proximal portion of the needle base 6, wherein a joint preventing means 90 which prevents the joining means 21 and the joined means 61 from being joined unintentionally before use, and allows joining to each other when in use is provided.

Abstract: Syringes and methods of using are described which protect the syringe barrel cavity from contaminants. A syringe is formed with an end cap contaminant shield having an extension wall that is mated with the rearward end opening of the syringe barrel cavity. Alternatively, the end cap contaminant shield can be provided with a flat design without the extending wall and is bonded or molded to the rearward end terminus of the syringe barrel. The end cap contaminant shield designs are provided with an opening defining the shape of the cross-section of the plunger shaft.

Abstract: A device for pre-treating and injecting a liquid specimen includes a first syringe including an open top first tube including a first hole in the bottom and protrusions, a second syringe including an open top second tube including a second hole in the bottom and an inner diameter greater than an outer diameter of the first tube, a second piston movable along an inner wall of the second tube and including a third hole and a communication channel providing fluid communication between the first hole and the third hole, and a joint portion attachable to and detachable from a top of the second tube and including an opening corresponding to a transverse cross-section of the first tube and grooves corresponding to the shape of the protrusions such that the first tube passes through the joint portion when the protrusions are matched with the grooves.

Abstract: Apparatus for sealing a puncture communicating with a blood vessel includes a porous carrier formed from lyophilized hydrogel or other material. The plug may include at least first and second hydrogel precursors and a pH adjusting agent carried by the porous carrier in an unreactive state prior to exposure to an aqueous physiological environment. Once exposed to bodily fluids, the carrier expands as the lyophilized material hydrates to enhance and facilitate rapid hemostasis of the puncture. When the plug is placed into the puncture, the natural wetting of the plug by bodily fluids (e.g., blood) causes the first and second precursors to react and cross-link into an adhesive or “sticky” hydrogel that aids in retaining the plug in place within the puncture.

Abstract: A syringe includes a hollow barrel, a hollow plunger movable within the barrel and a needle assembly secured within and at a distal end of the barrel. The needle assembly includes a needle holder, a resilient member that biases the needle holder toward the proximal end opening of the barrel, and a retaining member releasably secured to the needle holder via a reduced material section. The retaining member maintains the needle holder at the distal end of the barrel against the bias of the resilient member. When the plunger is fully depressed within the barrel, the plunger engages the needle holder such that the retaining member is forced to break away and separate from the needle holder along the reduced material section to facilitate retraction of the needle holder and a needle secured to the needle holder into the retraction cavity disposed within the plunger.

Abstract: A spray or injection device that includes a casing or a pusher that includes at least one tab radially moveable between a first radial position, in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position and then allow it to return to the first radial position. The pusher or the casing further includes at least one stop between the pusher and casing to delineate the end of a first stroke corresponding to a first dose of medicament, and the beginning of a second stroke corresponding to a second dose of medicament.

Abstract: An operable single-use syringe includes a barrel having an inside surface defining a chamber for retaining fluid and an open proximal end. A plunger rod having an elongate body portion and a stopper at its distal end slidably positioned in fluid-tight engagement in the barrel. A locking element is positioned in the barrel between the plunger rod and the inside surface of the barrel. The locking element has a base and two leg members projecting therefrom that are positioned in longitudinal grooves in the plunger rod. The locking element only moves distally in the barrel and prevents re-use of the syringe after its contents have been discharged.

Abstract: An ophthalmic injection device includes a dispensing chamber housing with an inner surface that partially defines a dispensing chamber for holding a substance, a plunger fluidly sealed to the interior surface of the dispensing chamber housing, and a needle fluidly coupled to the dispensing chamber. A temperature control device partially surrounds the dispensing chamber housing and alters a temperature of the substance. A piston is coupled to the plunger at one end and to a spring at the other end. The spring provides a force to drive the piston and the plunger. An actuator is coupled to the lockout bar with which a button is configured to interface. The actuator moves the lockout bar when the substance reaches a temperature, thereby allowing the button to be activated so that the spring provides the force to drive the plunger. An incorporated stop whose measurements may vary allow the expelled dosage to vary accordingly.

Abstract: An injection system includes a syringe, which preferably includes larger and smaller inner diameters, and a plunger. A wiper sidewall of the plunger defines a cavity, into which a plunger shaft of the system is inserted, for moving the plunger, within the syringe, for fluid injection. The plunger includes a feature for engaging the shaft, and the sidewall preferably includes a expandable-contractible portion, in which the feature is formed. When the plunger is initially mounted within the larger inner diameter of the syringe, the portion of the sidewall is expanded and the feature of the plunger does not operably engage the inserted shaft. When the shaft moves the plunger into the smaller inner diameter of the syringe, the portion of the sidewall contracts and the feature operably engages the shaft. An optional deformable end wall of the plunger may be spaced apart from a distal terminal end of the inserted shaft.

Abstract: A spray or injection device that includes a casing or a pusher that includes at least one tab configured to move radially between a first radial position in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The tab includes an opening. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position then to penetrate the opening thereby allowing the tab to return to the first radial position. The pusher or the casing, respectively, further includes at least one stop region against which the tab abuts when the tab is brought into the second radial position by the projection. The stop region occurring just before the projection being opposite the opening.

Abstract: An intravenous catheter introducing device includes a needle hub slidably inserted into a barrel and holding a needle cannula, a biasing member disposed to bias the needle hub to a rear position so as to retract the needle cannula in the barrel, and an easy release unit including an engaging wall segment which is attached to an outer surface of the barrel, two flexible squeezed wall segments which extend from the engaging wall segment and which is squeezable so as to move two latch members to steer clear of a retained end of the needle hub through an access hole in the barrel, thereby permitting the biasing member to bias the needle hub towards the rear position.

Abstract: A disposable injector with a housing (10) in which are arranged at least one mechanical spring energy store (50), at least one cylinder-piston unit that can be filled at least temporarily with an active substance, at least one piston actuation plunger (60) and at least one triggering unit (80). The spring energy store comprises at least one pre-loaded spring element. The spring-loaded piston actuation plunger has at least one traction rod (61) which can be moved transversely, at least in certain regions, and by means of a supporting portion supports the tensioned spring energy store on at least one resting surface (37) of the housing. An actuatable triggering slide device (82) unlocks the disposable injector and releases the supporting portion to allow it to move away from the resting surface.