Abstract: A syringe including a barrel, a needle subassembly holder positioned in the barrel, and a needle subassembly positioned in the holder. The needle subassembly includes a needle hub releasably connected to the holder and a needle connected to the hub. Further, the syringe includes a piston slidably received by the barrel. The piston includes a piston body and a piston head having a releasable portion temporarily covering a hatchway. The piston also includes a valve positioned proximal of the hatchway and movable between blocking and passing positions. A user may push the piston distally beyond an injected position in which the piston head contacts the holder causing the holder to move distally and the hub to contact the barrel, causing the barrel to bow, thereby storing potential energy.

Abstract: Medical devices having restrictive access, and methods thereof are provided.

Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.

Abstract: A system to minimize fluid turbulence inside a tissue cavity during endoscopic procedures. A body tissue cavity of a subject is distended by continuous flow irrigation using a solenoid operated pump on the inflow side and a positive displacement pump, such as a peristaltic pump, on the outflow side, such that the amplitude of the pressure pulsations created by the outflow positive displacement pump inside the said tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method for accurately determining the rate of fluid loss into the subject's body system during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors. The present invention also provides a system of creating and maintaining any desired pressure in a body tissue cavity for any desired cavity outflow rate.

Abstract: A syringe and a method of using the syringe are disclosed. The syringe includes a longitudinal body having proximal and distal ends and including an aperture between the proximal and distal ends. An injectable material, such as an adhesive bone cement, may be loaded into the body of the syringe through the aperture. After the injectable material is inserted, the aperture may be closed by covering the aperture with an aperture cover. The aperture cover may be configured to slide into a position covering the aperture, or the aperture cover may be placed in a position covering the aperture, such as by pivoting about a hinge. After the aperture is closed, the injectable material may be dispensed from the distal end of the syringe body by depressing a plunger. Depressing the plunger may initiate the closing of the aperture, or the aperture may be closed independently of plunger movement.

Abstract: A liquid medication dispenser includes a housing that has open top and bottom. The housing includes a central channel and a plurality of internal compartments disposed around the central channel. Each internal compartment is configured to hold liquid medication. The central channel is provided with symmetrically disposed bottom apertures configured to open into respective internal compartments. A shaft is configured to rotate and advance within the central channel. The shaft has a bottom hollow portion and at least one lateral aperture thereon configured to align with each one of the bottom channel apertures. The lateral shaft aperture aligns with a respective bottom channel aperture to allow transfer of liquid medication under gravity from the corresponding internal compartment into the bottom hollow portion of the shaft. The bottom hollow portion is apertured at one end to allow for transferred liquid medication to drip out of the dispenser in a controlled fashion.

Abstract: A syringe (12) having: a syringe body (18) in which a passage (28) for the circulation of fluid is defined, the circulatory passage (28) being extended by a main element (20) for fluidic connection to a complementary volume (13); and a movable piston (36) inside the syringe body (18), defining, with the syringe body (18), a chamber for the containment of fluid, opening out through the circulatory passage (28). The syringe body (18) defines a closed space in which the piston (36) is movably mounted. The piston (36) also defines in the closed space an auxiliary return chamber. The syringe body (18) defines a return passage (48) opening out into the auxiliary return chamber (46). The return passage (48) is extended by an auxiliary element (50) for connection to the complementary volume (13).

Abstract: A filler instrument comprises a first chamber section having a first cross sectional area and a second chamber section having a second cross sectional area less than the first cross sectional area. The second chamber section communicates with the first chamber section. The first chamber section includes an inlet for receiving a material into the filler instrument, and the second chamber section includes an outlet for discharging the material from the filler instrument. A first plunger is sized to pass through the first chamber section and not the second chamber section. A second plunger is sized to pass through an interior bore of the first plunger and into the second chamber section. In use, the first plunger displaces material residing in the first chamber section through the second chamber section toward the outlet, and the second plunger displaces material residing in the second chamber section through the outlet.

Abstract: The present invention includes a syringe device that includes an elongated tubular barrel having a first end and a second end, a plunger telescopically received within at least a portion of the barrel, such that a portion of the plunger extends from the first end of the barrel, and a protective sheath positioned adjacent to an external surface of the portion of the plunger, such that the protective sheath encloses the portion of the plunger extending outwardly from the first end of the barrel. The present invention further includes methods of transporting a biological material within the syringe device, and transferring the biological material between a source container and the syringe device.

Abstract: A reagent and related method for use in passivating a biomaterial surface, the reagent including a latent reactive group and a bifunctional aliphatic acid (e.g., fatty acid), in combination with a spacer group linking the latent reactive group to the aliphatic acid in a manner that preserves the desired function of each group. Once bound to the surface, via the latent reactive group, the reagent presents the aliphatic acid to the physiological environment, in vivo, in a manner (e.g., concentration and orientation) sufficient to hold and orient albumin.

Abstract: A disposable syringe (100) comprises an internally hollow syringe body (1) open at the front and rear, a plunger (40) slidable inside the syringe body (1) and provided at the rear with a shaft (50) operated manually through the rear end (80) thereof, an injection needle (10) integral with a needle carrier (11), a supporting body (20), accommodating the needle carrier (11) in a removable manner and engaging with the fore end (2) of the syringe body (1), elastic means (30) disposed under compression between the needle carrier (11) and the supporting body (20), a diaphragm (62) removably mounted in the shaft head (51) to cover a shaft inner chamber and engagement means (60) in the shaft head (51) cooperating with reciprocal engagement means (13) in the needle carrier (11) to cause disengagement of the needle carrier from the supporting body (20), when the plunger (40) reaches an injection stroke end, so that the elastic means (30), expanding, retract the needle carrier (11) which abuts against the diaphragm (62)

Abstract: A safe syringe having been drawn to a negative pressure status by an inner tube inside the plunge, a grip inserted to the top of the plunge that holds against each other with a catch of the syringe; upon completing the injection, the position of the plunge is changed to release the needle from the syringe, and the grip from the plunge for the negative pressure inside the plunge to fast suck the needle into the inner tube of the plunge, thus to be concealed in the plunge to prevent infection by any one due to accidental sting by the needle.

Abstract: The present invention is related with an improved syringe having a novel piston design. The syringe comprises an outer tube or cylinder made of, for example, plastic material, narrowed at its outlet for fitting a detachable hollow needle. Inside the outer tube the novel piston is slidable fitted including at its forward end a coupling defined by a coupling bolt and a retaining head which form part of the piston body. To the coupling a rubber bulb is rotatably fitted including a longitudinal hole for allowing fluids flow from tube to the needle and from the piston to the tube. The forward end of the piston includes an orifice defining fluid communication between the inner volume of the hollow piston and the inner volume of the tube. During the operation the piston can be rotated so as to align the hole of said rubber bulb and said orifice of the piston forward end for defining a fluid channel from the syringe to the hollow needle.

Abstract: An injection syringe for injecting a fluid into the arterial, venous, muscular or cavity structures of a patient via subcutaneous, percutaneous, intravascular and other types of injections comprises a hollow syringe body, a passageway at a distal end of the syringe for passage of fluid into and out of the syringe and a substantially open proximal end for receiving a plunger assembly. The plunger assembly includes a movable plunger assembly. A moveable plunger cooperates with the syringe body and the proximal end of the syringe to define a fluid chamber of variable volume in fluid communication with the passageway. Actuating means actuates movement of the plunger. An elastomeric barrier cooperates with the plunger and the open end of the syringe to define a sterile chamber between the actuating means and the fluid chamber to prevent passage of fluids from the fluid chamber to the actuating means and the passage of contaminants from the open end of the syringe in the fluid chamber.

Abstract: The present invention is a plastic container coated with a multi-layer barrier coating. The multi-layer barrier coating is useful for providing an effective barrier against gas permeability in containers and for extending shelf-life of containers, especially plastic evacuated blood collection devices.

Abstract: The present invention is a plastic container coated with a barrier coating. The barrier coating is useful for providing an effective barrier against gas permeability in containers and for extending shelf-life of containers, especially plastic evacuated blood collection devices.

Abstract: A compound or composition incorporating silver carbonate is disclosed for use in removing excess hydrogen ions in a patient. The silver carbonate reacts with chloride ions which naturally occur in the patient's body fluids to produce a silver chloride precipitate. The chemical reaction producing silver chloride causes the release of hydroxyl, carbonate and/or bicarbonate ions which react with free hydrogen ions to form carbon dioxide and water. The silver carbonate compound or composition may be provided in a blood filtration cartridge, syringe or an orally ingestible form surrounded by a selectively permeable membrane. The membrane is selected to permit movement of ions, as well as carbon dioxide and water molecules therethrough, while preventing the silver carbonate or silver chloride precipitate from being released into the patient.

Abstract: A liquid can be dosed advantageously using a syringe-like device, from a container fitted thereon, by means of a plunger mounted displaceably in a dosing chamber, this dosing chamber being connected to the container via a channnel passing through this plunger, a valve and a channel arranged together with the plunger in a connection tube.

Abstract: A syringe is described which is used in an improved method of vaccinating an animal. The syringe includes a one-piece barrel and needle comprised of a suitable injection molded plastic such as a polycarbonate material with the needle normally being enclosed or shielded by a flexible nasal tip-cap seal. The syringe is filled with a freeze-dried vaccine at the factory and is shipped to the point of use in a sealed pouch. The nasal tip-cap seal is placed in engagement with the cap or cover of a vial containing a diluent such as sterile water. The syringe is moved relative to the vial to cause the needle to pierce through the cover of the vial so that the distal end of the needle is in communication with the interior of the vial. The contents of the vial are then drawn inwardly into the syringe.

Abstract: An IV injection site adapted to receive a blunt cannula. The injection site comprises a housing having a passageway extending inwardly from its outside end, and an elastomeric septum closely received in the passageway of the housing. The septum has a bore extending into the septum from the inside end of the septum but not through the septum, and a slit extending generally in the axial direction into the septum from the outside end of the septum to the bore. When a cannula is introduced through the slit of the septum, the elastomeric material of the septum is displaced into the bore of the septum to sealingly engage the cannula along the bore of the septum.

Abstract: A medical syringe has a plunger bore (1 and 2) that is flexible. A hermetically-sealed glass ampule (3) containing a drug in the form of a liquid referred to generally as a sterile preparation (4) is placed in the plunger bore (1 and 2). When the plunger (1) is pulled outwardly a select distance to expose the flexible plunger bore (2), the glass ampule (3) is broken by hand-squeezing the plunger bore (2) against it. Liquid preparation (4) from the glass ampule (3) is directed through a check-valved orifice (16) at a tip of a resilient piston section (21) of the plunger (1). At the check-valved orifice (16), the preparation (4) enters into a syringe bore (6). There the preparation (4) can be injected through a conventional luer (38-40) and hypodermic needle (37) by the standard practice of depressing the plunger (1) into the syringe (7). Variations are provided for storing ampules of preparation either in or separately from the syringe. Embodiments are described for various adaptations.

Abstract: A pledget containing an anticoagulant for use with a blood sample is provided. The pledget includes a filler material, such as dextran, to increase the volume anticoagulant to minimize interference with free ion measurements in the blood.

Abstract: Process for the preparation in a series of self-injectable syringes characterized mainly by the fact that multiple seal tubes are placed vertically on an appropriate support, that a syringe body is placed vertically in each seal tube, that, into each tubular body thus arranged, a single dose of the medication in solution in a solvent is placed in each seal tube, above the syringe body, a plunger suspended by its pusher in a movable manner, at the lower end of a stopper which can adapt to the seal tube, so that said plunger is essentially in the axis of the syringe body and the lower end of said plunger is located above the upper end of the syringe body, with said stopper being held in a position so that said seal tube is not blocked or is not entirely blocked, to thus obtain an assembly constituting an open system in which the internal space, in the seal tubes and above said solution in the syringe bodies, is connected with the outside of the system, that the lyophilization operation is effected and, at this

Abstract: A method and apparatus for collecting saliva from a test subject comprises providing a flavored absorbent mass, such as a sponge, for mastication and charging with saliva and then expressing the saliva from the mass. Apparatus for this method comprises a barrel-piston arrangement in association with a specimen vial for storage until diagnostic testing.

Abstract: A prepackaged dispensing system for a two part permanent adhesive including an adhesive portion and an activator portion. The adhesive portion is housed in the main hollow body of a syringe-like member between an initially closed discharge means end and a sealing piston initially spaced axially form said discharge means end. A removably capped elongated dispensing container, adapted to contain and dispense the activator portion, is telescopically positioned within the hollow body and engages the piston. The combined total axial length of the piston and dispensing container when aligned exceeds the internal length of the hollow main body whereby axial pressure on said container will move said piston and insures substantially total discharge of said adhesive by movement of said piston to the discharge end of said hollow body.

Abstract: The invention relates to an automatic syringe comprising a combination of a discharge mechanism, a cartridge holder and a cartridge which is slidably accommodated in the cartridge holder. The cartridge comprises an ampoule containing one or more injection liquids, a piston movable in the ampoule and a hypodermic needle which is connected to the front of the ampoule and, if desired, is covered by a sheath to maintain the needle in a sterile condition. The discharge mechanism is provided with a power source which can move the cartridge from an inoperative to an operative condition. Also present are locking means for controlling the actuation of the power source and a safety device for blocking said locking device.The automatic syringe of the invention is characterized in that it comprises a tablet holder which can contain one or more tablets.The invention also relates to a tablet holder for the above syringe.

Abstract: A method and apparatus for collecting saliva from a test subject comprises providing a flavored absorbent mass, such as a sponge, for mastication and charging with saliva and then expressing the saliva from the mass. Apparatus for this method comprises a barrel-piston arrangement in association with a specimen vial for storage until diagnostic testing.