Abstract: A catheter insertion device includes a hollow needle attached to a needle base. A compression spring mechanically biases the needle base away from a plunger. A catheter is configured to be contactable by the plunger when the plunger moves in a forward direction. An expandable chamber is in fluidic and/or pneumatic communication with the hollow needle. The plunger inserts the catheter when a vacuum formed in the expandable chamber by the compression spring pushing the plunger away from the needle base is released by a fluid and/or a gas entering the hollow needle at a distal skin-piercing end as it punctures a vein or artery. A generally hollow housing includes an annularly-shaped seal relief formed as an inside surface where in a stored position a second circumferential seal captured by the plunger is not in contact with the inside surface of the generally hollow housing.

Abstract: A dental dispenser that receives a cartridge and a blunt tip applicator for the safe and controlled extrusion and placement of dental materials such as non-injectable anesthetics.

Abstract: An injection needle assembly is presented having an injection needle; a tubular needle holder having distal engagement means and proximal engagement means; a tubular cap having proximal outer engagement means and proximal inner engagement means; a tubular needle cover having first engagement means arranged to cooperate with the proximal engagement means, and second engagement means arranged to cooperate with the proximal outer engagement means of the cap. A needle cover is arranged to be displaced from a first position wherein the second engagement means and the proximal outer engagement means prevents the needle cover and the needle holder to be axially displaced by a linear displacement, to a second position wherein the needle cover and the needle holder are distally displaced where the needle holder can be displaced distally, but not proximally.

Abstract: A drug delivery device is provided herein, the device including a reservoir for containing a medicament. The medicament includes a suspension of solids in a liquid carrier. The device also includes a needle having a distal end for injection into a patient, a proximal end in communication with the reservoir, and a lumen extending between the distal and proximal ends. A path is defined from the reservoir to the distal end of the needle through the lumen, the path having an inner diameter that decreases in a proximal to distal direction along at least a portion thereof. Advantageously, with the subject invention, a flow path may be defined which provides a more gradual transition in diameter from the reservoir to a distal tip of the needle. In this manner, changes in velocity of the suspension may be less abrupt than in the prior art, thus better maintaining solid particles in the suspension.

Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).

Abstract: An injection device has a dispensing chamber housing, a plunger, and a temperature control device. The dispensing chamber housing has a first part and a second part. The first part is thermally coupled to a needle. The second part is thermally coupled to the first part. The second part has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with an inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering a temperature of the substance in the dispensing chamber. The second part has a greater thermal coefficient than the first part.

Abstract: A power injector syringe assembly (110) is disclosed. The power injector syringe assembly (110) includes a power injector syringe (112) and coupling (130) that are permanently joined. The coupling (130) includes a wedge-shaped mounting flange (144) to facilitate installation of the assembly (110) on a syringe mount (200) of a power injector. The coupling (130) also includes at least one coupling member (150) to facilitate removal of the assembly (110) from the syringe mount (200).

Abstract: The invention relates to an injection device for the needle-free injection of a medium. Said injection device comprises an injector device and an ampoule unit, said ampoule unit comprising a base (4) holding the medium to be injected. Said base comprises a jacket (5) which exerts pressure on the base, and jacket completely enveloping the base in the longitudinal axial direction.

Abstract: An actuating mechanism for a hypodermic syringe comprises a flexible tongue (48) allowing the actuating mechanism to be bent to receive a cartridge (10) of injectant closed at its forward end with a septum (14) and at its rearward end with a slidable bung (18). The forward end of the cartridge (10) is fitted into a socket (36) wherein the tail (34a) of a hypodermic needle (34) pierces the septum (14) to access the injectant. With the cartridge (10) fitted, the tongue (48) is straightened, and a spring clip (50) holds the cartridge (10) in position. A plunger (38) can then be depressed, though a guide (42), to drive the bung (18) forward and make the injection. The cartridge (10), which may be a conventional cartridge of any kind, keeps the assembly rigid in use, and the whole assembly is disposed of after a single use, without dismantling.

Abstract: An apparatus that includes two syringes, or a “double barrel syringe,” includes one syringe that injects or infuses while the other syringe aspirates. In the double barrel syringe, injection and aspiration may be effected by a single action. The double barrel syringe may include a handle with two members. A first member of such a handle includes one arm that pivotally couples to a plunger of a first syringe and another arm that pivotally couples to a barrel of a second syringe. A second member of the handle includes one arm that pivotally couples to a barrel of the first syringe and another arm that pivotally couples to a plunger of the second syringe. Methods for injecting or infusing simultaneously with aspirating are also disclosed.

Abstract: The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.

Abstract: A device for delivery of biologic materials, comprising: a cartridge having at least two cylinder bores for fluids to be delivered, wherein each cylinder includes an exit port for a fluid, a plunger within each cylinder for pushing the fluids out of the cylinder, a housing adapted to receive the cartridge, wherein the housing or cartridge includes an adaptor to receive and lock a manifold that operably connects to the exit ports of the cartridge, at least two toothed rams, wherein each toothed ram is at least partially within a cylinder bore, a trigger connected to the housing, wherein the trigger includes a toothed drive rack, a toothed wheel assembly that cooperates with the toothed drive rack and with the toothed rams, as well as methods of making the device, methods of using the device to treat discs, kits including the device.

Abstract: An ophthalmic injection device has a dispensing chamber housing, a plunger, an actuator for driving the plunger, a temperature control device, and a temperature release mechanism. The dispensing chamber housing has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering the temperature of the substance in the dispensing chamber. The temperature release mechanism is in a locked position when the substance is outside the proper temperature range and an unlocked position when the substance is in the proper temperature range.

Abstract: An injection device for injecting selectable amounts of a substance includes an activating mechanism including an axially moveable operating button which can rotated in a resting position only, a tubular drive element non-rotatably connected to the operating button, an axially fixed and non-rotatable guiding element, and an axially moveable driven member held non-rotatably in the device. A rotational grid is operationally between rotatable and non-rotatable components of the injection device such that the operating button can be moved two rotational directions when in the resting position whereby a selected amount of the substance to be injected can be selectively varied. For example, a dosage inadvertently selected too large by rotating the operating button too far in one direction can, in accordance with the present invention, be reduced by rotating the operating button in the opposite direction.

Abstract: An apparatus that includes two syringes, or a “double barrel syringe,” includes one syringe that injects or infuses while the other syringe aspirates. The double barrel syringe is a hand-held, hand-operated device with which injection and aspiration may be effected by a single action. The double barrel syringe may include a handle with two member. A first member includes one arm that pivotally couples to a plunger of a first syringe and another arm that pivotally couples to a barrel of a second syringe. A second member of the handle includes one arm that pivotally couples to a barrel of the first syringe and another arm that pivotally couples to a plunger of the second syringe. Methods for injecting or infusing simultaneously with aspirating are also disclosed.

Abstract: The present invention relates to a volume-adjustable micro-injection device. The device includes a base structure having a syringe positioning structure and a grip, in which the syringe positioning structure can flexibly accommodate injection syringes with different volumes; a holding structure capable of flexibly adjusting an injection angle of syringe content for easier operation; a qualitative controller capable of accurately controlling injection volume; a pressure pushing structure to hold and push a plunger; an injection controller interlinked with the qualitative controller and the pressure pushing structure; and an eject structure facilitating simple operation and easy replacement of injection syringes.

Abstract: A hand-held power syringe. The power syringe includes a handle with pivotally connected first and second members. The first member is also pivotally connectable to a syringe barrel, while the second member is pivotally connectable to a syringe plunger. These three pivotal connections provide leverage for forcing high viscosity fluids into and out of a receptacle of the syringe barrel. One or both of the first and second members of the handle may be bent to facilitate a user's gripping and movement of the first and second handle members. The power syringe may be used in any suitable injection, infusion, or sample-obtaining application, including angiography and angioplasty.

Abstract: Adjustable body penetrating blades of a min-retractor are inserted, closed together, into a small incision in an abdominal cavity, spread to widen the incision and a trocar tube is installed in the cavity by clamping between the blades enabling performance of a laparoscopic procedure in conjunction with other trocars inserted into other incisions. Rapid reversal of the laparoscopic procedure is achieved by moving the blades apart, releasing the trocar, and swinging distal ends of the blades apart expanding an inner operating window. A stand having a flexible positioning arm attached to the min-applicator maintains the min-retractor elevated after withdrawal of the trocar and loss of pneumoperitoneum pressure from insufflation. The blades of the mini-retractor gripping the tube of the trocar define between them a scalpel access opening to skin on respective opposite sides enabling enlargement of the incision with the retractor and trocar installed in the abdominal cavity.

Abstract: A right angle safety needle has a base to which an arm is hingedly mounted at a proximal portion. The base has an opening at its distal portion wherethrough the vertical portion of the right angle needle extends. A well is formed adjacent the opening and a dam is provided on the side of the well away from the opening. To retract the needle from the opening, the horizontal portion of the needle, which may be encased in an arm, is rotated about the upright to which it is hingedly connected so that the needle is pivoted upwards and withdrawn from the opening. Once the tip of the needle clears the opening, due to the tip of the needle being offset from the body of the needle and the fact that the needle tends to flex forward, the tip of the needle is entrapped in the well adjacent to the opening. The dam forward of the well provides a backstop for any further forward movement of the tip of the needle, thereby fixedly retaining the needle within the well.

Abstract: Two separate compositions, one containing multiple doses of an anhydrous first composition that includes a first active ingredient that is hydrolytically unstable and which provides a benefit to the skin of a user; and a second aqueous composition which may or may not contain a second active ingredient. are packaged within and dispensed from a common dispenser. By packaging these two compositions in this manner, long shelflife, good aesthetics and convenient dispensing and application are provided.

Abstract: An injection device has a housing (42) for receiving a container (50) having a liquid (49; 226′). In said container (50), a piston (90) is displaceably arranged so that by means of pressure upon the distal end of said piston (90), liquid can be expelled from the container (50). Arranged displaceably in the housing (42) is a tappet (92), which is configured for contact against the distal end of the piston (90) and which enables transfer of a force to the piston (90) in the proximal direction. Associated with the tappet (92) and displaceable relative thereto is a member (91) which at its proximal end region can be joined to the piston (90) in such a way that it enables the transfer of a force in the proximal direction and the transfer of a force in the distal direction to the piston (90).

Abstract: The pressure jacket systems of the invention are used to permit the front loading and removal of a syringe from an injector and include a first jacket segment and a second jacket segment surrounding the exterior surface of the syringe, interior surfaces comformable to the exterior surface of the syringe, a mechanism which allows movement of the first jacket segment in relation to the second jacket segment to permit insertion and removal of the syringe from the pressure jacket, and a mechanism for securing the first and second jacket segments in a fixed relationship upon insertion of the syringe.

Abstract: An apparatus for delivering fluid, or power syringe, comprises a base, a lever, and a syringe. The syringe has a reservoir adapted for holding a quantity of fluid and a plunger disposed within the reservoir and adapted for movement therein. The reservoir features a clip on one end which releasably secures the end of the reservoir to the base and an inwardly facing annular flange on the second end which substantially prevents the plunger from being removed from the reservoir and substantially prevents leakage. The base of the apparatus features an extension beyond the end of the reservoir containing the clip, thereby providing stability to the apparatus during operation. The plunger features a clip on one end which releasably secures the plunger to the lever.

Abstract: A medicament container has a body having an open mouth defining an axis, a pierceable plug engaged over and sealing the mouth, a ring engaged around the mouth and over the plug and formed with a hole through which an outer surface of the plug is exposed, and a cap engageable around the mouth over the ring and plug. The cap holds an elastomeric element bearing elastically through the hole against the plug outer surface.

Abstract: A closed delivery system is described for the handling of injectable biological products and vaccines used in the treatment and prevention of livestock diseases. This system embodies a multidose prefilled disposable cartridge and a metered pistolgrip syringe body. The cartridge is breech loaded into the syringe body and the product is dispensed from the cartridge by a unique drag link mechanism as a means for advancing the plunger rod and forcing the vaccine from the cartridge into the flesh of the animal being treated. Each prefilled cartridge is disposed of after it is emptied and no cleaning is required. A color coding system between the multidose, prefilled, disposable cartridges and the syringe bodies insure that proper dosages are given and that products are not mixed up or confused by the technicians administering the products.

Abstract: A syringe apparatus includes a housing having upper and lower end portions and a hollow interior. A rotary cam position inside the hollow interior has a projecting portion for operating a cartridge when the apparatus is used. The housing has a rotary bearing for supporting the cam. A syringe cartridge (single chamber or dual chamber) removably fits the housing interior, the cartridge including a barrel with at least one chamber for containing medicine to be dispensed and a dispensing orifice. The cartridge includes a piston having an upper plunger that engages the cam. The piston slides within the barrel chamber forcing contained medicine through the dispensing orifice (e.g., needle) during use. The upper plunger end of the piston engages the rotary cam during dispensing. The cam is movable between first and second positions, the second position being a dispensing position that positions the projecting portion of the cam at the piston. A spring urges the cam to rotate from the first to the second position.

Abstract: A power syringe (10) for use in medical procedures, such as angiography, delivers air or fluid, such as contrast medium, to a patient at operator controlled rates and pressures. In one embodiment, mechanical advantage is created by first and second arms (22, 26) which are interconnected with each other, the base, and the plunger (20). The proximal end of the syringe contains a track (44) that the plunger follows in normal fashion in and out of the reservoir. The track is bevelled from proximal to distal end to create a path with variable resistance. A mechanical stop (42) is at the proximal end of the track to control the length of travel of plunger and secondary mechanical arm. Markings (18) on reservoir (12) indicate the volume of fluid or air in the reservoir. Mechanical arm length, tracking length, and distance to plunger stop will vary with size of syringe to generate appropriate flow and power.

Abstract: Disclosed is a closed system for the handling of injectable biological products and vaccines used in the treatment and prevention of livestock diseases. This system embodies a prefilled disposable cartridge (44) with disposable needle (48) attached and a metered pistolgrip syringe. The cartridge (44) is breech loaded into the syringe and the product is dispensed from the cartridge by a unique drag link (22) mechanism as a means for advancing the plunger rod (36) and forcing the vaccine from the cartridge (44) into the flesh of animal being treated. Each prefilled cartridge is disposed of after it is emptied and no cleaning is required. A color coding system between the prefilled cartridges 44 and the and the syringe bodies insure that proper dosages are given and that different products are not mixed up or confused with each other by the technicians dispensing the biological products.

Abstract: A one-piece disposable syringe system is disclosed including a conventional syringe having a glass barrel that is prefilled with a measured dose of pharmaceutical and a syringe support and disposal jacket that is adapted to hold the syringe in an injection mode to facilitate the administration of an injection of the pharmaceutical from the barrel and surround the syringe in a disposal mode to form a compact package and thereby facilitate the safe handling and disposal of the syringe while avoiding an accidental needle stick and the possible spread of contagious disease. The syringe support and disposal jacket has lower and upper body members that are rotatably connected together by an integral living hinge.

Abstract: An improved intravascular catheter placement device for semi-automatic insertion, i.e. manually triggered self-propelled insertion, of an intravascular catheter into the interior of a blood vessel comprising a hollow needle, an intravascular catheter concentric with said hollow needle, a chamber in communication with said hollow needle wherein the pressure within said chamber is a vacuum pressure and self-propelling means for moving said catheter into a blood vessel upon penetration of the wall of the blood vessel by the tip of the hollow needle.The self-propelling means acting upon the catheter is manually actuated by the operator of the device upon visualization of the backflow of blood occurring upon penetration of the blood vessel by the tip of the needle, said backflow of blood being accelerated into said chamber by the vacuum pressure present within said chamber.

Abstract: A medicine dispensing device including a slotted housing, a front end, a rear end, at least one threaded portion in the vicinity of the rear end, a dosage ampoule fitting in the vicinity of the front end and a discharge conduit for connection with a discharge ampoule. A hollow screw-threaded device receives the ampoule therein. The screw-threaded device is received by the rear end of the housing. The screw-threaded device includes an exterior surface provided with a threaded surface engaging the at least one threaded portion for securing the ampoule within the housing. A medicine discharge and metering device for metering and discharging the contents of the ampoule is received within the screw-threaded device and is movable in a direction of a longitudinal axis thereof.

Abstract: An improved intravascular catheter placement device, for the automatic insertion of intravascular catheter into the interior of blood vessels comprising a needle, an intravascular catheter concentric to the needle, and self-propelling means for moving said catheter into a blood vessel upon needle penetration of the wall of the blood vessel. The self-propelling means is actuated by means for sensing penetration of a blood vessel.

Abstract: An adapter is provided for enabling the single-handed use of a syringe for aspiration. An assembly including such an adapter is also provided. The adapter includes an elongate body portion including a first end portion which functions as a thumb pad and a second end portion secured to the syringe barrel. A winged member is secured to the syringe plunger and includes a pair of flanges extending outside the adapter. The syringe plunger may be retracted using only one hand by pulling the flanges of the winged member with the index and middle fingers while maintaining the thumb upon the first end portion of the adapter.

Abstract: A syringe holder for administering the contents of prefilled cartridge-cannula units comprises generally a cartridge holding barrel rotatably connected to a push rod guiding sleeve, and a push rod slidably mounted in the sleeve.

Abstract: A squeezing finger pressure is exerted on a trigger mechanism carried by a finger-grip portion of a hypodermic syringe. The depressed trigger mechanism displaces a V-shaped lock spring inwardly, moving a bight portion of the spring out from locking engagement with a lock opening. This frees a compressed compression spring allowing it to drive an internal bushing, a cartridge within a barrel portion of the syringe, a second bushing at the front end of the syringe, and a needle forwardly together, relative to the finger-grip body and the barrel of the syringe. This is done for the purpose of penetrating a needle into tissue in which an injection is to be made.

Abstract: The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising dial-up cam arranged to receive and engage with a dial-up key, wherein the dial-up cam and the dial-up key are adapted to, upon rotation of a dose setting member in a first direction, cooperate to strain the torsion spring of the injection device, and a dial-down cam arranged to receive and engage with a dial-down key, wherein the dial-down cam and the dial-down key are adapted to, upon rotation of the dose setting member in a second direction, cooperate to release the torsion spring of the injection device, the second rotation direction being opposite to the first rotation direction.