Abstract: A syringe assembly includes a plate-shaped seal member that seals a distal opening of a distal nozzle portion of a syringe; and a tubular cover member. The cover member has a base portion and a mounting portion. The mounting portion has two claw portions, two first column portions arranged on both sides of one of the two claw portions, and two second column portions arranged on both sides of the other of the two claw portions. An outer peripheral portion of the mounting portion has two outer peripheral notch portions. An inner peripheral portion of the mounting portion has two inner peripheral recessed portions.

Abstract: An apparatus for entirely removing a medical sharp from a holder to which it is connected, including a body (102), a heating unit (104) disposed in the body, a receiving unit (114) fixedly disposed in the body and configured to receive the holder, and a collet (122) movably disposed within the body and configured to receive the medical sharp. The apparatus also includes a first biasing member (130) disposed within the body, and a user interface (136) coupled to the collet and configured to displace the collet away from the receiving unit, actuate the first biasing member to increase a bias on the collet toward the receiving unit, and actuate the heating unit.

Abstract: Provided is an apparatus, system, and method for a nested syringe assembly. The nested syringe assembly includes a first syringe having a cylindrical body defining an inner diameter and a second syringe having a cylindrical body defining an outer diameter. The outer diameter of the second syringe is less than the inner diameter of the first syringe. At least a portion of the cylindrical body of the second syringe is disposed within the cylindrical body of the first syringe.

Abstract: The present invention relates to a device for measuring, recording, and acting in response to changes in air pressures encountered through the lumen of a connected needle. The device signals when it has been powered and signals when the device recognizes both pressures and pressure change rates indicative of synovial cavity joint penetration, such as knee joint penetration. Synovial cavity pressures detected and acted upon may either be supra- (positive) or sub-atmospheric (negative). Internal light emitting diodes and a laptop connected display are demonstrated as signaling and communication mechanisms. Methods for delivering medicaments into human and animal intra-articular cavities or joints such as synovial cavities are provided. Furthermore, methods for facilitating the diagnoses of joint effusion also are provided.

Abstract: An injector includes a needle movable from a retracted position to an injection position. A rotary biasing assembly is stabilized in a stored energy state and releasable into an energy releasing state and includes a cam. A cam follower couples the rotary biasing assembly with the needle and is configured to transform rotation of the rotary biasing assembly in the energy releasing state thereof into translation of the needle from the retracted position to the injection position. An activation switch is rotatable from an unactivated position, stabilizing the rotary biasing assembly in the stored energy state thereof, to an activated position, releasing the rotary biasing assembly into the energy releasing state thereof. An activation button is movably mounted to the injector housing and is translatable from an unactuated position to an actuated position, whereby the translation rotates the activation switch from the unactivated position to the activated position thereof.

Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

Abstract: A syringe having an enteral collar with a vent is disclosed. The syringe may also include a plug which reversibly covers the vent. Other embodiments relate to the use of the syringe. The vent allows fluid within the region between the enteral collar and the tip to be removed.

Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device includes a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector defines a sterile fluid flowpath between the container and the insertion mechanism. A cannula initially disposed about the needle is included.

Abstract: The invention is directed to a method for using a polymer composition for connecting a first object to a second object, wherein the method comprises, the step of applying a polymer composition to at least part of the surface of at least one of the first object or second object; connecting the first object and the second object at the surface where the polymer composition is applied and irradiating the polymer composition using UV-radiation over a first time period, obtaining a UV radiated polymer composition; irradiating the UV radiated polymer composition with gamma-radiation over a second time period obtaining a gamma radiated polymer. The invention also relates to a system of a plastic object and a metal object connected by the method of the invention.

Abstract: A cannula includes a bowl portion with at least one depression in its outer surface, a tube portion, and a plurality of welds located at the at least one depression and joining the bowl portion to the tube portion. The plurality of welds may be discrete welds spaced from one another along a circumferential direction of the cannula. The weld joining a cannula bowl portion and a tube portion may be spaced from the distal end of the bowl portion. Various exemplary embodiments further contemplate methods of manufacturing a cannula by welding a tube portion and a bowl portion. Welding may occur, for example, in at least one depression of the bowl portion to form discrete welds spaced from one another along a circumferential direction of the cannula. In another example, welding may occur at a location spaced from and proximal to a distal end of the bowl portion.

Abstract: A needle and syringe system that provides ultra-low dosage waste and automatic needlestick protection. A syringe assembly is provided that contains a barrel and a plunger. A tubular spacer is disposed in the barrel. A needle head assembly is provided that includes a collar and a needle. A safety slide is positioned between the needle and the collar. The safety slide has a sheathing tube that surrounds part of the needle. The safety slide can move relative the needle. In a first position, the sheathing tube does not extend beyond the sharpened end of the needle. In a second position, the sheathing tube extends beyond the sharpened end of the needle. When advanced, the plunger head moves the tubular spacer. The tubular spacer passes over the base of the needle and presses against the safety slide. The safety slide is moved from the first position to the second position.

Abstract: A fluid delivery device and system is operable to fluidly couple a pair of fluid delivery conduits. One embodiment includes a fluid delivery device sized to meet ANSI/AAMI ID54:1996(R) 2005 and not mate with ANSI/HIMA MD70.1 or ISO 594/1 and ISO 594/2 standards for intravenous ports and connectors to prevent accidental intravenous delivery of fluids intended for enteral delivery. The system includes at least one of a locking tab and a stop flange configured to not mate with matching connectors not configured to satisfy the enteral feeding standards and not specifically configured to mate with the fluid delivery device.

Abstract: A syringe having barrel and a non-luer tip that is not connectable to an intravenous device is disclosed. The syringe as an enteral collar engagement feature adjacent the distal end of the syringe barrel. The syringe has an enteral collar having a distal end and proximal end, the proximal end having a syringe engagement feature complementary to and engagable with the enteral collar engagement feature.

Abstract: A syringe comprising a syringe barrel having a distal end, a distal tip, an open proximal end, a barrel sidewall extending between the distal end to the open proximal end and defining a chamber, the barrel sidewall having a barrel sidewall thickness t, the distal end of the syringe barrel including a distal wall is disclosed. The syringe includes a connector integrally formed with and extending distally from the syringe barrel at the distal wall, the connector including a collar disposed coaxially around an elongate tip in fluid communication with the barrel to form a channel between the elongate tip and the collar, the collar including an inside surface, an outside surface and a plurality of ribs extending radially outwardly from the outside surface and separated by spaces, each of the plurality of ribs having a height H and a width W, wherein there is a ratio of the height H to the barrel sidewall thickness tin a range of 0.75 and 1.

Abstract: A low-waste needle and syringe assembly for injecting a fluid into a patient is provided. The syringe has hatch marks printed on the outer wall of the body to indicate the amount of fluid and/or the concentration of the fluid contained in a fluid chamber of the syringe. A syringe tip defining a substantially frusto-conical interior void extends from an end wall of the syringe. A needle hub holds a needle and is configured so that the hub can be selectively and securedly attached to the syringe. A frusto-conical member of the needle hub matingly engages the frusto-conical void of the syringe tip when the hub is secured to the syringe, forming a fluid-tight seal. A plunger positioned in the fluid chamber can be depressed by a user, and a piston cap attached to the plunger urges fluid in the chamber out of the chamber through the syringe tip and into the needle. The piston cap matingly engages the end wall of the syringe so that substantially all fluid is urged from the chamber to the needle.

Abstract: A needle actuator assembly for a drug delivery system includes a housing, a needle having retracted and extended positions, a needle actuator body received within the housing and configured to move from a pre-use position where the needle is in the retracted position to a use position where the needle is in the extended position and to a post-use position where the needle is in the retracted position, with the needle actuator having a button contact surface, and an actuator button received by the housing.

Abstract: A needle changing device for use on a medication delivery device includes an engagement element that is configured to engage the medication delivery device and pierce a septum of the medication delivery device, a needle holder connected to the engagement element, the needle holder having a needle changing septum having a reservoir, the reservoir being in continuous fluid communication with the engagement element, and a plurality of needles configured to pierce the needle changing septum, wherein when the needle holder is in a first position, the plurality of needles are disengaged from the reservoir of the needle changing septum, and when the needle holder is in a second position, one of the plurality of needles enters into fluid communication with the reservoir of the needle changing septum and is partially exposed outside the needle changing device for medicament delivery.

Abstract: An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle.

Abstract: Embodiments of the present invention disclose a device for removing adipose tissue with a needle(s), comprising a needle hub that comprises at least one needle that contains between 1-1000 holes around the circumference of the needle barrel which allows passage of adipose tissue and other lipoaspirate, and an adipose tissue collection and purification device comprising a plurality of self-contained syringes wherein each of the syringes comprises an inner syringe included within an outer syringe and wherein a filter is attached inside the outer syringe barrel, the filter having a mesh pore size between 30 micro meters and 1000 micro meters, the device being attached to a needle hub. The present invention further provides a system for closed adipose tissue harvesting, purification, and grafting, comprising an adipose tissue removal component, a collection and purification component, and a grafting component. Methods of using the devices or system are also disclosed.

Abstract: Embodiments of the present invention disclose a device for removing adipose tissue, comprising a self-contained syringe device comprising an inner syringe included within an outer syringe and wherein a filter is attached inside the outer syringe barrel; wherein the filter comprises a filter material that prevents premature filter collapse where the filter material is optionally coated to increase stiffness, and wherein liposuctioned adipose tissue is collected and purified inside the syringes. Methods of using the devices or system are also disclosed.

Abstract: A positioning device with sensing capacities is provided, which facilitates needle or catheter introduction into a body tissue or cavity and is configured to sense the types of encountered tissue. Using the epidural access procedure as an example, device and method designs are presented, which enable the sensing of needle entrance to the epidural space and anchoring of the cannula within the ligamentum flavum tissue to prevent puncturing of the dura mater. In case of tissue sensing by an expandable balloon, balloon fluid pressure and volume are used to indicate tissue and cavity characteristics encountered during the procedure. Device embodiments, device construction methods and treatment methods are provided.

Abstract: The present invention relates to a medical device protection assembly and to a respective medical device. The protection assembly comprises at least one reorientation member being connectable with a medical device and being operable to orient the medical device into a predefined orientation in the event the medical device is subject to a free-fall.

Abstract: An aspiration probe tip for use in surgical procedures includes a body defining a first channel therein for aspirating material therethrough from a surgical region along a first vector. The body includes a straight portion connected to a first end and a curved portion connecting the straight portion to a second end. A fluid sleeve surrounds at least a portion of the body and defines a second channel between the fluid sleeve and the body for injecting a fluid into the surgical region along a second vector. An end of the fluid sleeve securely fits over the body to substantially seal the end of the fluid sleeve. The fluid sleeve further defines an aperture for injecting fluid along the second vector from the second channel into the surgical region.

Abstract: A surgical system combines a cannula and an instrument in a manner that allows small gauge instruments to be used effectively, with little or no bending with respect to the manipulating proximal side of the instrument. Such design overcomes the shortcomings of prior art, and applies to various microsurgical procedures, including ophthalmology, allowing the use of smaller endo-photocoagulation probes, illumination probes, combination probes, vitrectors, scissors, manipulators, picks, diathermy, and others. By using smaller gauge, patient recovery is expected to be faster.

Abstract: A retractable self-destructing safety syringe with pre-attached needle including a barrel, an inner needle base disposed in a barrel neck at an end of the barrel body, and an elastic engagement mechanism formed between the barrel neck and the inner needle base is provided. An asymmetric elastic locking member having an elastic function is disposed at the end of the plunger, with which a sleeve-type retractable locking member on the needle base can be interlocked by the elastic function. After being retracted into the barrel body, the needle base together with the needle will be forced to deflect to one side under an asymmetric force, and the needle therefore will be forced to incline in a direction nearly a 45 degree angle toward to one side of the inner wall of the barrel and is blocked by the barrel neck, so that the needle and the needle base could not be pushed out the barrel neck again and self-destruction of the syringe is truly achieved.

Abstract: A device is presented for injection of a product into an injection site, comprising: a container provided with a needle, a housing receiving the container, and a needle shield releasably coupled with the container. The device also includes a retaining arrangement provided at or near the distal end of the device, designed for preventing the container from moving distally with respect to the housing until the needle shield is removed from the container.

Abstract: An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle.

Abstract: An intradermal injection device comprising a unitary body having an open distal end and a proximal end having a skin engaging surface defined thereon, a reservoir defined between the proximal and distal ends for accommodating a drug substance, and a channel defined at the proximal end of the unitary body and extending through, and distally from, the skin engaging surface to the reservoir. A needle cannula having a sharpened proximal end and a distal end may be provided in the channel. The needle cannula is secured in the channel with the distal end being in communication with the reservoir and the proximal end of the needle cannula extending from the skin engaging surface a distance in the range of about 0.5 mm to 3.0 mm such that the skin engaging surface limits penetration of the proximal end of the needle cannula to the dermis layer of the skin of a patient.

Abstract: A device having a housing; a cannula projecting forwardly from the housing; a connector useful for attaching the device to a fluid source or receptacle; a fluid flow path establishing fluid communication between the cannula and the connector; a retraction mechanism biasing the cannula away from its projecting position; and an actuator supported by the housing and configured to modify the fluid flow path so as to terminate fluid flow through the device, seal off the fluid flow path, and release the retraction mechanism to retract the cannula into the housing. The subject device is particularly preferred for use in the medical field, for example, as part of an infusion set or as a collection device for blood, or other fluids or flowable matter.

Abstract: An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle.

Abstract: A probe head is disclosed that is detachable from a probe body containing electronics. The probe head includes a housing enclosing a sensor and at least part of an electrical connector electrically coupled to the sensor. The housing has a coupling member positioned to detachably connect the housing to the probe body, and when the probe head and probe body are coupled, the electrical connector electrically couples the sensor to the electronics within the probe body. The probe head may be disposable.

Abstract: A pen needle assembly having a hub with an increased surface area that contacts a patient's skin is provided. The increased contact area of the hub with the patient's skin during injection of a cannula decreases the pressure exerted against the patient's skin, thereby increasing the comfort of the patient. A bonding adhesive is disposed on an outer surface of the hub, thereby decreasing the required curing time of the adhesive. Additionally, the increased contact area, between the cannula adhesive and hub increases the strength of the bond therebetween.

Abstract: A plunger, a needle assembly and a retractable syringe comprising same are provided. The plunger comprises a plunger member and a plunger outer having a lock spring that prevents or impedes movement of the plunger member after needle retraction. The plunger further comprises another locking member for engaging the barrel to prevent or impede further movement of the plunger outer after delivery of fluid contents. The plunger member has a plunger seal which engages a retractable needle of the needle assembly for retraction. The retractable needle comprises a cannula and needle body with a plurality of fluid channels that co-operate with a fluid conduit of the plunger seal to efficiently direct fluid to the cannula. A needle retainer comprises a plurality of barbed arms releasably coupled to the needle body, whereby an ejector with tabs facilitates release of the retractable needle from the needle retainer to allow compressed spring-driven retraction.

Abstract: Various needle tip storage and removal devices are disclosed which include a housing with a separate storage compartment and removal compartment for receiving a needle tip. The removal compartment is designed to hold securely a used needle tip. The removal compartment may have a one way snap engagement and/or a movable closure element.

Abstract: Systems and methods for placement of an introducer needle into the subclavian vein. A needle for subclavian vein penetration includes a straight needle portion, a bent needle portion, and a hub. The bent portion allows for needle placement with minimized chance of complications. The needle and hub form a lumen through which a guide wire can be placed. The bent needle portion has an inner diameter substantially similar to the inner diameter of the straight needle portion to reduce resistance due to movement of the guide wire.

Abstract: Medical device assemblies having a connection mechanism for securely connecting a hub to fluid storage containers in a luer slip relationship are described. An exemplary medical device includes a hub forming a cavity, a second indicating element disposed within the cavity that engages the hub. Additional features of the medical device include a second indicating element contoured to form a line contact with the hub. In a specific configuration, the hub includes a first indicating element attached to the hub and extending proximally into the cavity having a protrusion. In a more specific configuration, the medical device includes a fluid storage container that has an indication system for visually indicating optimal fluid-tight engagement of the hub and the fluid storage container.

Abstract: A syringe adapter for use on multiple sized syringes comprising: a neck, where the neck is capable of connecting to a syringe; a flange positioned just below the neck; a base portion positioned abutting the flange positioned just below the flange; and a tapered sleeve below the flange. The syringe adaptor may further include a cap that inserts into the neck of the syringe adaptor during non-use. In one particular embodiment, the cap includes a top flat portion and a stem that goes into the neck. Also, the syringe adaptor may include a cover that fits over the tapered sleeve during non-use.

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

Abstract: The present invention provides a safety syringe which resolves a problem in the prior art whereby the needle assembly does not engage the plunger properly due to limitations in the syringe protrusion molding. The syringe of the present invention comprises: a cylinder which has a space therein to contain fluid and forms a fluid discharging portion at one end; a plunger which is inserted inside the cylinder and slid in a longitudinal direction; a piston which is associated with the upper portion of the plunger in order to make airtight contact between the plunger and the cylinder; a syringe needle assembly which is equipped at the upper portion of the cylinder and affixes a syringe needle. The syringe needle assembly is inserted into and contained inside the cylinder after use and is then disposed. In the needle assembly, plural needle supports comprising a first connector and a second connector are extended to the lower portion.

Abstract: A Luer securement device comprising a Luer adapter having a septum and a catheter hood, the Luer adapter further having a wedge seal for receiving a base portion of a catheter. The Luer securement device further includes an inserter body in which is slidably housed a catheter threader having a probe which is configured to advance a base portion of a catheter through the septum thereby seating the base portion of the catheter into the wedge seal of the Luer adapter as a tip portion of the catheter is inserted into a patient. The catheter threader further includes a needle adapter having a needle which is threaded through the probe and the catheter to assist in inserting the catheter into the patient. Following insertion of the catheter, the catheter threader is retracted within the inserter body thereby withdrawing the needle from the catheter and shielding a sharpened tip of the needle within at least one of the inserter body and the catheter threader.

Abstract: Medical device assemblies having a connection mechanism for securely connecting a hub to fluid storage containers in a luer slip relationship are described. An exemplary medical device includes a hub forming a cavity, a second indicating element disposed within the cavity that engages the hub. Additional features of the medical device include a second indicating element contoured to form a line contact with the hub. In a specific configuration, the hub includes a first indicating element attached to the hub and extending proximally into the cavity having a protrusion. In a more specific configuration, the medical device includes a fluid storage container that has an indication system for visually indicating optimal fluid-tight engagement of the hub and the fluid storage container.

Abstract: The present invention relates to a delivery member attachment device (10) comprising a neck (12) having an inner space intended to accommodate a connection part of a medicament container, which neck (12) is intended to receive a delivery member (30) for creating a passage between the medicament container via the connection part and through the delivery member, that said neck (12) is arranged with threads (14) arranged to engage with corresponding threads (34) of an attachment part (32 of said delivery member (30), and wherein said neck (12) further is arranged with a number of slits (16) providing a number of tongues (18) between said slits, and wherein said tongues (18) are arranged to flex inwards, when a delivery member (30) is to be attached, to allow an axial pushing of said attachment part (32) onto, and in engagement with, said neck (12).

Abstract: The present invention relates to a method of producing syringes. Said method comprises fixing a needle to a syringe body by use of an adhesive followed by subjecting the syringes thus obtained to heat treatment. The invention further relates to a method of reducing leachables and/or extractables in prefilled syringes, said method comprising heat treating pre-fabricated syringes at a temperature of at least 40° C. before filling.

Abstract: An adapter and syringe assembly is described in this application which includes a syringe and an adapter for anti-rotation, removal resistant connection to the syringe. The syringe has a body defining a fluid reservoir, a plunger assembly including a plunger head dimensioned to be slidably received within the reservoir, a fluid outlet, and a first coupling member. The adapter has a body portion defining a fluid channel, a collar portion, and a second coupling member configured to engage the first coupling member to secure the adapter to the syringe. The syringe includes at least one rib and a surface of the collar includes at least one protrusion. The at least one rib and the at least one protrusion are configured and positioned to interact to facilitate attachment of the adapter to the syringe but to resist detachment of the oral dose tip adapter from the syringe. The body portion of the adapter may define an oral dose tip or a needle hub assembly.

Abstract: Described is a needle assembly comprising a needle hub adapted to mount at least one medical needle. According to the invention, the needle hub is designed as a releasable clamping element which interchangeably holds the medical needle wherein the releasable clamping element is adapted to mount the medical needle in a non-positive locking manner and/or a positive locking manner in a holding position.

Abstract: A needle assembly for a medical device comprising a needle cannula which is mounted in a hub connectable to a medical device, and which needle assembly comprises releasable locking means which co-operates with the connection means of the hub such that the needle cap is locked to the hub when the releasable locking means is not released. Once the locking means is released by activation of the connection means, the needle cap is unlocked from the hub. The activation of the locking means is preferably done automatically when the needle assembly is attached to the medical device.

Abstract: A medical connector includes a body defining a lumen for fluid flow through the medical connector. The medical connector includes a luer member and an annular member disposed about the luer member. The annular member includes internal and/or external engagement structures. The medical connector may be provided on the outlet of a syringe or on a catheter. A fluid path is disclosed including a first section and a second section. The first and second sections may each include a medical connector to provide a removable connection with a syringe and a catheter, respectively. The medical connector may provide a removable connection between the first and second sections. A fluid delivery system is disclosed including an injector, a syringe operatively associated with the injector, and a fluid path connecting the syringe and a source of injection. The medical connector may provide a removable connection between the syringe and fluid path.

Abstract: Described is a needle assembly attachment and removal device comprising a case having a base and a longitudinal axis (L), a carriage axially movable with the case from a first position to a second position, a carrier rotatably coupled to the carriage and adapted to hold a needle assembly, and a gearing arrangement rotatably coupled to the carriage and adapted to rotate the carrier in a first rotational direction as the carriage moves from the first position to the second position and in a second rotational direction as the carriage moves from the second position to the first position.

Abstract: The invention relates to a glass syringe-side assembly element for providing an interface element between a glass syringe including on its front side a syringe cone part with a syringe needle and including on its rear side a flange part and a glass syringe operating means, where the assembly element can be arranged on the outer contour of the glass syringe, and where the assembly element can be secured to the assembly element relative to the syringe needle in front of the flange part on the glass syringe such that a reference point of the assembly element is always at a defined distance from the needle tip of the syringe needle.

Abstract: A cannula assembly (10) comprising a hub (76) and a cannula (12) mounted in the hub (76). The cannula defines an inner space (36). The cannula comprises a distal end (16) and a proximal end (18). A first medicament (40) is provided in the inner space of the cannula. In one arrangement, the hub of the cannula assembly is configured to be coupled to an injection device (26). The cannula assembly may be removably or permanently coupled to the injection device containing a second medicament (17).